Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | RB_DN.V1_DN |
| Enrichment Score (ES) | 0.55876195 |
| Normalized Enrichment Score (NES) | 1.4516081 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.047733873 |
| FWER p-Value | 0.14 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CISH | cytokine inducible SH2 containing protein [Source:HGNC Symbol;Acc:HGNC:1984] | 6 | 4.858 | 0.0444 | Yes |
| 2 | TNC | tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] | 7 | 4.846 | 0.0889 | Yes |
| 3 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 34 | 4.388 | 0.1285 | Yes |
| 4 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 37 | 4.297 | 0.1678 | Yes |
| 5 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 91 | 3.660 | 0.2000 | Yes |
| 6 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 109 | 3.552 | 0.2321 | Yes |
| 7 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 111 | 3.533 | 0.2645 | Yes |
| 8 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 183 | 3.113 | 0.2912 | Yes |
| 9 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 307 | 2.582 | 0.3116 | Yes |
| 10 | CHAC1 | ChaC glutathione specific gamma-glutamylcyclotransferase 1 [Source:HGNC Symbol;Acc:HGNC:28680] | 475 | 2.152 | 0.3268 | Yes |
| 11 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 485 | 2.127 | 0.3461 | Yes |
| 12 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 530 | 2.034 | 0.3636 | Yes |
| 13 | HSPA5 | heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238] | 541 | 2.024 | 0.3819 | Yes |
| 14 | ATF5 | activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790] | 610 | 1.899 | 0.3974 | Yes |
| 15 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 657 | 1.811 | 0.4128 | Yes |
| 16 | CD9 | CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709] | 709 | 1.741 | 0.4274 | Yes |
| 17 | PSMB10 | proteasome 20S subunit beta 10 [Source:HGNC Symbol;Acc:HGNC:9538] | 713 | 1.734 | 0.4432 | Yes |
| 18 | SLC7A5 | solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063] | 913 | 1.510 | 0.4517 | Yes |
| 19 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 1007 | 1.423 | 0.4623 | Yes |
| 20 | MMP13 | matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159] | 1021 | 1.417 | 0.4749 | Yes |
| 21 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 1294 | 1.218 | 0.4787 | Yes |
| 22 | ANKFY1 | ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20763] | 1397 | 1.150 | 0.4865 | Yes |
| 23 | DYNLL1 | dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476] | 1649 | 1.049 | 0.4894 | Yes |
| 24 | DDX3Y | DEAD-box helicase 3 Y-linked [Source:HGNC Symbol;Acc:HGNC:2699] | 1747 | 1.006 | 0.4960 | Yes |
| 25 | PPP2R1B | protein phosphatase 2 scaffold subunit Abeta [Source:HGNC Symbol;Acc:HGNC:9303] | 1894 | 0.947 | 0.5007 | Yes |
| 26 | BCCIP | BRCA2 and CDKN1A interacting protein [Source:HGNC Symbol;Acc:HGNC:978] | 2004 | 0.898 | 0.5060 | Yes |
| 27 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 2011 | 0.895 | 0.5141 | Yes |
| 28 | NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 [Source:HGNC Symbol;Acc:HGNC:7733] | 2084 | 0.864 | 0.5200 | Yes |
| 29 | CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Source:HGNC Symbol;Acc:HGNC:1769] | 2259 | 0.798 | 0.5227 | Yes |
| 30 | PRKAR1A | protein kinase cAMP-dependent type I regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9388] | 2272 | 0.794 | 0.5296 | Yes |
| 31 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 2405 | 0.750 | 0.5329 | Yes |
| 32 | DDIT3 | DNA damage inducible transcript 3 [Source:HGNC Symbol;Acc:HGNC:2726] | 2638 | 0.683 | 0.5329 | Yes |
| 33 | BASP1 | brain abundant membrane attached signal protein 1 [Source:HGNC Symbol;Acc:HGNC:957] | 2732 | 0.655 | 0.5364 | Yes |
| 34 | LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [Source:HGNC Symbol;Acc:HGNC:15606] | 2865 | 0.622 | 0.5386 | Yes |
| 35 | P4HA1 | prolyl 4-hydroxylase subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8546] | 2923 | 0.607 | 0.5426 | Yes |
| 36 | SH3BP5L | SH3 binding domain protein 5 like [Source:HGNC Symbol;Acc:HGNC:29360] | 3120 | 0.564 | 0.5425 | Yes |
| 37 | STARD3NL | STARD3 N-terminal like [Source:HGNC Symbol;Acc:HGNC:19169] | 3121 | 0.564 | 0.5476 | Yes |
| 38 | AGRN | agrin [Source:HGNC Symbol;Acc:HGNC:329] | 3176 | 0.550 | 0.5512 | Yes |
| 39 | DDIT4 | DNA damage inducible transcript 4 [Source:HGNC Symbol;Acc:HGNC:24944] | 3288 | 0.525 | 0.5531 | Yes |
| 40 | UBA5 | ubiquitin like modifier activating enzyme 5 [Source:HGNC Symbol;Acc:HGNC:23230] | 3293 | 0.524 | 0.5578 | Yes |
| 41 | NFIL3 | nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:HGNC:7787] | 3427 | 0.494 | 0.5587 | Yes |
| 42 | EFL1 | elongation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25789] | 3583 | 0.465 | 0.5588 | Yes |
| 43 | CAP1 | cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040] | 3826 | 0.420 | 0.5561 | No |
| 44 | ARL1 | ADP ribosylation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:692] | 3883 | 0.410 | 0.5583 | No |
| 45 | TMEM42 | transmembrane protein 42 [Source:HGNC Symbol;Acc:HGNC:28444] | 4354 | 0.330 | 0.5486 | No |
| 46 | MSMO1 | methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545] | 5025 | 0.226 | 0.5326 | No |
| 47 | PDCD6 | programmed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765] | 5265 | 0.191 | 0.5279 | No |
| 48 | LMAN1 | lectin, mannose binding 1 [Source:HGNC Symbol;Acc:HGNC:6631] | 5930 | 0.095 | 0.5108 | No |
| 49 | WNT3 | Wnt family member 3 [Source:HGNC Symbol;Acc:HGNC:12782] | 6123 | 0.075 | 0.5063 | No |
| 50 | EIF4E | eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:HGNC:3287] | 6158 | 0.071 | 0.5060 | No |
| 51 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 6273 | 0.055 | 0.5034 | No |
| 52 | TLL1 | tolloid like 1 [Source:HGNC Symbol;Acc:HGNC:11843] | 6379 | 0.041 | 0.5010 | No |
| 53 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 6478 | 0.032 | 0.4986 | No |
| 54 | NKAP | NFKB activating protein [Source:HGNC Symbol;Acc:HGNC:29873] | 6533 | 0.024 | 0.4974 | No |
| 55 | LAMC2 | laminin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:6493] | 6663 | 0.005 | 0.4939 | No |
| 56 | CALCB | calcitonin related polypeptide beta [Source:HGNC Symbol;Acc:HGNC:1438] | 9079 | 0.000 | 0.4286 | No |
| 57 | LCE5A | late cornified envelope 5A [Source:HGNC Symbol;Acc:HGNC:16614] | 9709 | 0.000 | 0.4116 | No |
| 58 | RASL11B | RAS like family 11 member B [Source:HGNC Symbol;Acc:HGNC:23804] | 10049 | 0.000 | 0.4024 | No |
| 59 | ADAM12 | ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190] | 10236 | 0.000 | 0.3974 | No |
| 60 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 10305 | 0.000 | 0.3955 | No |
| 61 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 11243 | 0.000 | 0.3702 | No |
| 62 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 11363 | 0.000 | 0.3670 | No |
| 63 | C10orf99 | chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428] | 11404 | 0.000 | 0.3659 | No |
| 64 | S100A16 | S100 calcium binding protein A16 [Source:HGNC Symbol;Acc:HGNC:20441] | 11954 | 0.000 | 0.3510 | No |
| 65 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 12029 | 0.000 | 0.3490 | No |
| 66 | AGR3 | anterior gradient 3, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:24167] | 12338 | 0.000 | 0.3407 | No |
| 67 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12704 | 0.000 | 0.3308 | No |
| 68 | MOXD1 | monooxygenase DBH like 1 [Source:HGNC Symbol;Acc:HGNC:21063] | 13236 | 0.000 | 0.3165 | No |
| 69 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 14026 | 0.000 | 0.2951 | No |
| 70 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16450 | 0.000 | 0.2296 | No |
| 71 | H19 | H19 imprinted maternally expressed transcript [Source:HGNC Symbol;Acc:HGNC:4713] | 17182 | 0.000 | 0.2098 | No |
| 72 | S1PR5 | sphingosine-1-phosphate receptor 5 [Source:HGNC Symbol;Acc:HGNC:14299] | 18000 | 0.000 | 0.1877 | No |
| 73 | BNC1 | basonuclin 1 [Source:HGNC Symbol;Acc:HGNC:1081] | 19252 | 0.000 | 0.1539 | No |
| 74 | GJB2 | gap junction protein beta 2 [Source:HGNC Symbol;Acc:HGNC:4284] | 20928 | 0.000 | 0.1086 | No |
| 75 | F2RL1 | F2R like trypsin receptor 1 [Source:HGNC Symbol;Acc:HGNC:3538] | 21172 | 0.000 | 0.1020 | No |
| 76 | LRRC4 | leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586] | 22778 | 0.000 | 0.0586 | No |
| 77 | C18orf32 | chromosome 18 open reading frame 32 [Source:HGNC Symbol;Acc:HGNC:31690] | 24525 | 0.000 | 0.0113 | No |
| 78 | CST9 | cystatin 9 [Source:HGNC Symbol;Acc:HGNC:13261] | 24730 | 0.000 | 0.0058 | No |
| 79 | FHL1 | four and a half LIM domains 1 [Source:HGNC Symbol;Acc:HGNC:3702] | 25835 | 0.000 | -0.0240 | No |
| 80 | SLCO2A1 | solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955] | 26608 | 0.000 | -0.0449 | No |
| 81 | ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10870] | 26987 | 0.000 | -0.0551 | No |
| 82 | CELSR1 | cadherin EGF LAG seven-pass G-type receptor 1 [Source:HGNC Symbol;Acc:HGNC:1850] | 27609 | -0.022 | -0.0717 | No |
| 83 | RPS2 | ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404] | 27818 | -0.048 | -0.0769 | No |
| 84 | FEZ2 | fasciculation and elongation protein zeta 2 [Source:HGNC Symbol;Acc:HGNC:3660] | 27853 | -0.052 | -0.0774 | No |
| 85 | RHOV | ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313] | 27872 | -0.056 | -0.0773 | No |
| 86 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 28211 | -0.096 | -0.0856 | No |
| 87 | TMEM50B | transmembrane protein 50B [Source:HGNC Symbol;Acc:HGNC:1280] | 28401 | -0.120 | -0.0896 | No |
| 88 | DNAJC4 | DnaJ heat shock protein family (Hsp40) member C4 [Source:HGNC Symbol;Acc:HGNC:5271] | 28430 | -0.121 | -0.0893 | No |
| 89 | SARAF | store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789] | 28534 | -0.132 | -0.0908 | No |
| 90 | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1 [Source:HGNC Symbol;Acc:HGNC:217] | 28549 | -0.134 | -0.0900 | No |
| 91 | CREB3L2 | cAMP responsive element binding protein 3 like 2 [Source:HGNC Symbol;Acc:HGNC:23720] | 28693 | -0.150 | -0.0925 | No |
| 92 | GOSR2 | golgi SNAP receptor complex member 2 [Source:HGNC Symbol;Acc:HGNC:4431] | 29385 | -0.235 | -0.1090 | No |
| 93 | MYORG | myogenesis regulating glycosidase (putative) [Source:HGNC Symbol;Acc:HGNC:19918] | 29487 | -0.249 | -0.1095 | No |
| 94 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 29711 | -0.279 | -0.1129 | No |
| 95 | SMIM3 | small integral membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:30248] | 30232 | -0.341 | -0.1239 | No |
| 96 | IRX4 | iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6129] | 30457 | -0.372 | -0.1265 | No |
| 97 | CAV1 | caveolin 1 [Source:HGNC Symbol;Acc:HGNC:1527] | 30881 | -0.434 | -0.1340 | No |
| 98 | H2BC14 | H2B clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4750] | 30961 | -0.447 | -0.1320 | No |
| 99 | CYTH1 | cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501] | 31008 | -0.455 | -0.1291 | No |
| 100 | UROS | uroporphyrinogen III synthase [Source:HGNC Symbol;Acc:HGNC:12592] | 31190 | -0.483 | -0.1296 | No |
| 101 | ANKRD40 | ankyrin repeat domain 40 [Source:HGNC Symbol;Acc:HGNC:28233] | 31248 | -0.491 | -0.1266 | No |
| 102 | COL18A1 | collagen type XVIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2195] | 31325 | -0.503 | -0.1240 | No |
| 103 | TMCC3 | transmembrane and coiled-coil domain family 3 [Source:HGNC Symbol;Acc:HGNC:29199] | 31599 | -0.549 | -0.1264 | No |
| 104 | ANXA11 | annexin A11 [Source:HGNC Symbol;Acc:HGNC:535] | 31890 | -0.591 | -0.1288 | No |
| 105 | SQLE | squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279] | 32039 | -0.622 | -0.1271 | No |
| 106 | UNC119B | unc-119 lipid binding chaperone B [Source:HGNC Symbol;Acc:HGNC:16488] | 32365 | -0.691 | -0.1295 | No |
| 107 | PMVK | phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141] | 32578 | -0.739 | -0.1285 | No |
| 108 | MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24693] | 32653 | -0.758 | -0.1235 | No |
| 109 | TRAPPC12 | trafficking protein particle complex 12 [Source:HGNC Symbol;Acc:HGNC:24284] | 33017 | -0.846 | -0.1256 | No |
| 110 | SEC23A | Sec23 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10701] | 33360 | -0.937 | -0.1262 | No |
| 111 | SLC7A3 | solute carrier family 7 member 3 [Source:HGNC Symbol;Acc:HGNC:11061] | 33413 | -0.951 | -0.1189 | No |
| 112 | FAM102A | family with sequence similarity 102 member A [Source:HGNC Symbol;Acc:HGNC:31419] | 33614 | -1.006 | -0.1151 | No |
| 113 | CDC42SE2 | CDC42 small effector 2 [Source:HGNC Symbol;Acc:HGNC:18547] | 33794 | -1.052 | -0.1103 | No |
| 114 | CTNNAL1 | catenin alpha like 1 [Source:HGNC Symbol;Acc:HGNC:2512] | 33971 | -1.105 | -0.1049 | No |
| 115 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 34272 | -1.206 | -0.1020 | No |
| 116 | H2BC4 | H2B clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4757] | 34488 | -1.289 | -0.0959 | No |
| 117 | NSDHL | NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398] | 34776 | -1.408 | -0.0908 | No |
| 118 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 35569 | -1.827 | -0.0954 | No |
| 119 | ANXA6 | annexin A6 [Source:HGNC Symbol;Acc:HGNC:544] | 35766 | -1.976 | -0.0826 | No |
| 120 | PLXNA2 | plexin A2 [Source:HGNC Symbol;Acc:HGNC:9100] | 36634 | -2.879 | -0.0796 | No |
| 121 | LIFR | LIF receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6597] | 36640 | -2.888 | -0.0533 | No |
| 122 | NDRG1 | N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679] | 36838 | -3.276 | -0.0285 | No |
| 123 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36995 | -3.849 | 0.0026 | No |
