Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | RB_P107_DN.V1_UP |
| Enrichment Score (ES) | -0.72022146 |
| Normalized Enrichment Score (NES) | -1.5557348 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.017960718 |
| FWER p-Value | 0.022 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 99 | 3.625 | 0.0198 | No |
| 2 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 218 | 2.944 | 0.0349 | No |
| 3 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 246 | 2.791 | 0.0515 | No |
| 4 | FBN1 | fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603] | 422 | 2.289 | 0.0610 | No |
| 5 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 778 | 1.647 | 0.0616 | No |
| 6 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 1083 | 1.377 | 0.0619 | No |
| 7 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 1171 | 1.309 | 0.0677 | No |
| 8 | TRPV2 | transient receptor potential cation channel subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:18082] | 1952 | 0.917 | 0.0523 | No |
| 9 | TAGLN | transgelin [Source:HGNC Symbol;Acc:HGNC:11553] | 3635 | 0.453 | 0.0096 | No |
| 10 | FANCL | FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748] | 3669 | 0.448 | 0.0115 | No |
| 11 | H1-10 | H1.10 linker histone [Source:HGNC Symbol;Acc:HGNC:4722] | 4492 | 0.310 | -0.0089 | No |
| 12 | BGN | biglycan [Source:HGNC Symbol;Acc:HGNC:1044] | 5319 | 0.183 | -0.0301 | No |
| 13 | SPIRE2 | spire type actin nucleation factor 2 [Source:HGNC Symbol;Acc:HGNC:30623] | 5610 | 0.139 | -0.0371 | No |
| 14 | RBPMS2 | RNA binding protein, mRNA processing factor 2 [Source:HGNC Symbol;Acc:HGNC:19098] | 5649 | 0.135 | -0.0372 | No |
| 15 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 5781 | 0.117 | -0.0401 | No |
| 16 | BLVRB | biliverdin reductase B [Source:HGNC Symbol;Acc:HGNC:1063] | 5933 | 0.095 | -0.0436 | No |
| 17 | FBLN5 | fibulin 5 [Source:HGNC Symbol;Acc:HGNC:3602] | 6322 | 0.050 | -0.0537 | No |
| 18 | CES5A | carboxylesterase 5A [Source:HGNC Symbol;Acc:HGNC:26459] | 7084 | 0.000 | -0.0743 | No |
| 19 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 8456 | 0.000 | -0.1114 | No |
| 20 | CDH2 | cadherin 2 [Source:HGNC Symbol;Acc:HGNC:1759] | 9773 | 0.000 | -0.1470 | No |
| 21 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9978 | 0.000 | -0.1526 | No |
| 22 | ABAT | 4-aminobutyrate aminotransferase [Source:HGNC Symbol;Acc:HGNC:23] | 10844 | 0.000 | -0.1760 | No |
| 23 | FBLN2 | fibulin 2 [Source:HGNC Symbol;Acc:HGNC:3601] | 11548 | 0.000 | -0.1950 | No |
| 24 | LYPD1 | LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28431] | 12290 | 0.000 | -0.2150 | No |
| 25 | BICC1 | BicC family RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19351] | 12663 | 0.000 | -0.2251 | No |
| 26 | SLIT3 | slit guidance ligand 3 [Source:HGNC Symbol;Acc:HGNC:11087] | 12809 | 0.000 | -0.2290 | No |
| 27 | CDKN1C | cyclin dependent kinase inhibitor 1C [Source:HGNC Symbol;Acc:HGNC:1786] | 12851 | 0.000 | -0.2301 | No |
| 28 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 13113 | 0.000 | -0.2372 | No |
| 29 | COL1A2 | collagen type I alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2198] | 13114 | 0.000 | -0.2372 | No |
| 30 | TMEM119 | transmembrane protein 119 [Source:HGNC Symbol;Acc:HGNC:27884] | 13688 | 0.000 | -0.2527 | No |
| 31 | TMEM45B | transmembrane protein 45B [Source:HGNC Symbol;Acc:HGNC:25194] | 14930 | 0.000 | -0.2863 | No |
| 32 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 16132 | 0.000 | -0.3188 | No |
| 33 | SI | sucrase-isomaltase [Source:HGNC Symbol;Acc:HGNC:10856] | 16354 | 0.000 | -0.3247 | No |
| 34 | EFS | embryonal Fyn-associated substrate [Source:HGNC Symbol;Acc:HGNC:16898] | 16423 | 0.000 | -0.3266 | No |
| 35 | COL16A1 | collagen type XVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2193] | 16560 | 0.000 | -0.3303 | No |
| 36 | BEX2 | brain expressed X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30933] | 16654 | 0.000 | -0.3328 | No |
| 37 | SRPX2 | sushi repeat containing protein X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30668] | 17552 | 0.000 | -0.3570 | No |
| 38 | COL6A2 | collagen type VI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2212] | 18719 | 0.000 | -0.3886 | No |
| 39 | COL6A1 | collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211] | 18720 | 0.000 | -0.3886 | No |
| 40 | FKBP10 | FKBP prolyl isomerase 10 [Source:HGNC Symbol;Acc:HGNC:18169] | 18975 | 0.000 | -0.3955 | No |
| 41 | KHDRBS3 | KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117] | 19635 | 0.000 | -0.4133 | No |
| 42 | LOXL1 | lysyl oxidase like 1 [Source:HGNC Symbol;Acc:HGNC:6665] | 19768 | 0.000 | -0.4169 | No |
| 43 | COL5A1 | collagen type V alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2209] | 20319 | 0.000 | -0.4317 | No |
| 44 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 21123 | 0.000 | -0.4535 | No |
| 45 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 21359 | 0.000 | -0.4598 | No |
| 46 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 21876 | 0.000 | -0.4738 | No |
| 47 | COX6B2 | cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380] | 24332 | 0.000 | -0.5402 | No |
| 48 | TSSC4 | tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;Acc:HGNC:12386] | 24634 | 0.000 | -0.5484 | No |
| 49 | SNCG | synuclein gamma [Source:HGNC Symbol;Acc:HGNC:11141] | 25702 | 0.000 | -0.5772 | No |
| 50 | KCNA1 | potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218] | 27633 | -0.025 | -0.6293 | No |
| 51 | NAA40 | N-alpha-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845] | 28515 | -0.131 | -0.6523 | No |
| 52 | TEK | TEK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11724] | 28904 | -0.178 | -0.6617 | No |
| 53 | DYNLT1 | dynein light chain Tctex-type 1 [Source:HGNC Symbol;Acc:HGNC:11697] | 29485 | -0.249 | -0.6758 | No |
| 54 | TCFL5 | transcription factor like 5 [Source:HGNC Symbol;Acc:HGNC:11646] | 29752 | -0.282 | -0.6813 | No |
| 55 | CA2 | carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] | 29806 | -0.289 | -0.6809 | No |
| 56 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 30127 | -0.328 | -0.6876 | No |
| 57 | ANAPC11 | anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452] | 30385 | -0.362 | -0.6923 | No |
| 58 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30480 | -0.375 | -0.6925 | No |
| 59 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 30692 | -0.405 | -0.6957 | No |
| 60 | SAMD10 | sterile alpha motif domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16129] | 30862 | -0.432 | -0.6976 | No |
| 61 | MRGPRF | MAS related GPR family member F [Source:HGNC Symbol;Acc:HGNC:24828] | 30892 | -0.435 | -0.6956 | No |
| 62 | MFGE8 | milk fat globule EGF and factor V/VIII domain containing [Source:HGNC Symbol;Acc:HGNC:7036] | 31127 | -0.470 | -0.6991 | No |
| 63 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 31262 | -0.494 | -0.6996 | No |
| 64 | PIDD1 | p53-induced death domain protein 1 [Source:HGNC Symbol;Acc:HGNC:16491] | 31528 | -0.536 | -0.7035 | No |
| 65 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 31537 | -0.537 | -0.7003 | No |
| 66 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 31617 | -0.551 | -0.6991 | No |
| 67 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 31752 | -0.570 | -0.6991 | No |
| 68 | PTMA | prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623] | 31862 | -0.586 | -0.6985 | No |
| 69 | CDH11 | cadherin 11 [Source:HGNC Symbol;Acc:HGNC:1750] | 32326 | -0.683 | -0.7067 | No |
| 70 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32680 | -0.764 | -0.7115 | No |
| 71 | IPO9 | importin 9 [Source:HGNC Symbol;Acc:HGNC:19425] | 32871 | -0.808 | -0.7117 | No |
| 72 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 32902 | -0.817 | -0.7074 | No |
| 73 | ORC6 | origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151] | 33074 | -0.861 | -0.7067 | No |
| 74 | NELFE | negative elongation factor complex member E [Source:HGNC Symbol;Acc:HGNC:13974] | 33217 | -0.898 | -0.7050 | No |
| 75 | HEXD | hexosaminidase D [Source:HGNC Symbol;Acc:HGNC:26307] | 33782 | -1.049 | -0.7137 | Yes |
| 76 | FANCA | FA complementation group A [Source:HGNC Symbol;Acc:HGNC:3582] | 33866 | -1.073 | -0.7093 | Yes |
| 77 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 34110 | -1.145 | -0.7088 | Yes |
| 78 | PCOLCE | procollagen C-endopeptidase enhancer [Source:HGNC Symbol;Acc:HGNC:8738] | 34111 | -1.146 | -0.7016 | Yes |
| 79 | TRPM1 | transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146] | 34155 | -1.163 | -0.6956 | Yes |
| 80 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 34224 | -1.190 | -0.6900 | Yes |
| 81 | GINS4 | GINS complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:28226] | 34681 | -1.364 | -0.6939 | Yes |
| 82 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 34764 | -1.403 | -0.6874 | Yes |
| 83 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 34852 | -1.446 | -0.6808 | Yes |
| 84 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 34892 | -1.469 | -0.6727 | Yes |
| 85 | DCLRE1A | DNA cross-link repair 1A [Source:HGNC Symbol;Acc:HGNC:17660] | 34985 | -1.505 | -0.6659 | Yes |
| 86 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 34998 | -1.516 | -0.6568 | Yes |
| 87 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35050 | -1.543 | -0.6486 | Yes |
| 88 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 35084 | -1.562 | -0.6398 | Yes |
| 89 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 35321 | -1.686 | -0.6357 | Yes |
| 90 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 35364 | -1.711 | -0.6262 | Yes |
| 91 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 35419 | -1.743 | -0.6169 | Yes |
| 92 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 35422 | -1.744 | -0.6061 | Yes |
| 93 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35525 | -1.805 | -0.5977 | Yes |
| 94 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 35533 | -1.810 | -0.5866 | Yes |
| 95 | RPA2 | replication protein A2 [Source:HGNC Symbol;Acc:HGNC:10290] | 35535 | -1.811 | -0.5754 | Yes |
| 96 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 35643 | -1.882 | -0.5666 | Yes |
| 97 | PRIM2 | DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370] | 35686 | -1.917 | -0.5558 | Yes |
| 98 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35722 | -1.939 | -0.5448 | Yes |
| 99 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 35900 | -2.083 | -0.5366 | Yes |
| 100 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 35993 | -2.147 | -0.5258 | Yes |
| 101 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35994 | -2.147 | -0.5125 | Yes |
| 102 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35995 | -2.149 | -0.4991 | Yes |
| 103 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 35999 | -2.149 | -0.4859 | Yes |
| 104 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36041 | -2.186 | -0.4734 | Yes |
| 105 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36164 | -2.301 | -0.4624 | Yes |
| 106 | PAQR4 | progestin and adipoQ receptor family member 4 [Source:HGNC Symbol;Acc:HGNC:26386] | 36217 | -2.340 | -0.4493 | Yes |
| 107 | ETHE1 | ETHE1 persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287] | 36229 | -2.350 | -0.4350 | Yes |
| 108 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36274 | -2.405 | -0.4213 | Yes |
| 109 | POLE | DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177] | 36417 | -2.569 | -0.4092 | Yes |
| 110 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36434 | -2.597 | -0.3935 | Yes |
| 111 | RHEBL1 | RHEB like 1 [Source:HGNC Symbol;Acc:HGNC:21166] | 36520 | -2.717 | -0.3789 | Yes |
| 112 | RFC2 | replication factor C subunit 2 [Source:HGNC Symbol;Acc:HGNC:9970] | 36539 | -2.738 | -0.3624 | Yes |
| 113 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36551 | -2.763 | -0.3456 | Yes |
| 114 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36566 | -2.776 | -0.3287 | Yes |
| 115 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36589 | -2.814 | -0.3118 | Yes |
| 116 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36636 | -2.885 | -0.2952 | Yes |
| 117 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36676 | -2.954 | -0.2779 | Yes |
| 118 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 36728 | -3.048 | -0.2603 | Yes |
| 119 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36769 | -3.134 | -0.2420 | Yes |
| 120 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36808 | -3.196 | -0.2232 | Yes |
| 121 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36816 | -3.214 | -0.2034 | Yes |
| 122 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36860 | -3.318 | -0.1840 | Yes |
| 123 | WDHD1 | WD repeat and HMG-box DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23170] | 36875 | -3.369 | -0.1634 | Yes |
| 124 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36936 | -3.599 | -0.1427 | Yes |
| 125 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36962 | -3.693 | -0.1205 | Yes |
| 126 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 37009 | -3.919 | -0.0974 | Yes |
| 127 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 37014 | -3.953 | -0.0730 | Yes |
| 128 | TCF19 | transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11629] | 37022 | -3.987 | -0.0484 | Yes |
| 129 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 37030 | -4.032 | -0.0236 | Yes |
| 130 | VEGFB | vascular endothelial growth factor B [Source:HGNC Symbol;Acc:HGNC:12681] | 37033 | -4.057 | 0.0015 | Yes |
