Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | ZHONG_PFC_C2_UNKNOWN_NPC |
| Enrichment Score (ES) | -0.8263953 |
| Normalized Enrichment Score (NES) | -1.7166628 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1757 | 1.003 | -0.0384 | No |
| 2 | CNOT7 | CCR4-NOT transcription complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:14101] | 3441 | 0.490 | -0.0795 | No |
| 3 | TUBB6 | tubulin beta 6 class V [Source:HGNC Symbol;Acc:HGNC:20776] | 4617 | 0.292 | -0.1086 | No |
| 4 | KDM4A | lysine demethylase 4A [Source:HGNC Symbol;Acc:HGNC:22978] | 5436 | 0.164 | -0.1292 | No |
| 5 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 5637 | 0.136 | -0.1334 | No |
| 6 | CALB2 | calbindin 2 [Source:HGNC Symbol;Acc:HGNC:1435] | 9093 | 0.000 | -0.2267 | No |
| 7 | AC091057.1 | OTU deubiquitinase 7A pseudogene [Source:NCBI gene (formerly Entrezgene);Acc:100288637] | 13038 | 0.000 | -0.3333 | No |
| 8 | NDST4 | N-deacetylase and N-sulfotransferase 4 [Source:HGNC Symbol;Acc:HGNC:20779] | 13726 | 0.000 | -0.3519 | No |
| 9 | DNALI1 | dynein axonemal light intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:14353] | 17876 | 0.000 | -0.4639 | No |
| 10 | ZNF649 | zinc finger protein 649 [Source:HGNC Symbol;Acc:HGNC:25741] | 21417 | 0.000 | -0.5596 | No |
| 11 | AMBN | ameloblastin [Source:HGNC Symbol;Acc:HGNC:452] | 24595 | 0.000 | -0.6454 | No |
| 12 | MFAP2 | microfibril associated protein 2 [Source:HGNC Symbol;Acc:HGNC:7033] | 25517 | 0.000 | -0.6703 | No |
| 13 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29642 | -0.271 | -0.7793 | No |
| 14 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 29922 | -0.301 | -0.7841 | No |
| 15 | ITCH | itchy E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13890] | 31068 | -0.462 | -0.8109 | No |
| 16 | TRIM59 | tripartite motif containing 59 [Source:HGNC Symbol;Acc:HGNC:30834] | 31562 | -0.543 | -0.8193 | Yes |
| 17 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 31715 | -0.565 | -0.8183 | Yes |
| 18 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31738 | -0.568 | -0.8138 | Yes |
| 19 | TROAP | trophinin associated protein [Source:HGNC Symbol;Acc:HGNC:12327] | 32139 | -0.639 | -0.8188 | Yes |
| 20 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 32260 | -0.666 | -0.8161 | Yes |
| 21 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 32450 | -0.711 | -0.8148 | Yes |
| 22 | PIF1 | PIF1 5'-to-3' DNA helicase [Source:HGNC Symbol;Acc:HGNC:26220] | 32881 | -0.811 | -0.8191 | Yes |
| 23 | G2E3 | G2/M-phase specific E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:20338] | 32916 | -0.821 | -0.8126 | Yes |
| 24 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33320 | -0.929 | -0.8151 | Yes |
| 25 | DEPDC1 | DEP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22949] | 33362 | -0.938 | -0.8078 | Yes |
| 26 | RANGAP1 | Ran GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9854] | 33597 | -1.000 | -0.8051 | Yes |
| 27 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 33672 | -1.025 | -0.7979 | Yes |
| 28 | REEP4 | receptor accessory protein 4 [Source:HGNC Symbol;Acc:HGNC:26176] | 33683 | -1.029 | -0.7889 | Yes |
| 29 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 33831 | -1.063 | -0.7833 | Yes |
| 30 | ARL6IP1 | ADP ribosylation factor like GTPase 6 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:697] | 33946 | -1.095 | -0.7765 | Yes |
| 31 | ARHGAP11A | Rho GTPase activating protein 11A [Source:HGNC Symbol;Acc:HGNC:15783] | 33954 | -1.099 | -0.7668 | Yes |
| 32 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 34058 | -1.132 | -0.7593 | Yes |
| 33 | CKAP2L | cytoskeleton associated protein 2 like [Source:HGNC Symbol;Acc:HGNC:26877] | 34271 | -1.206 | -0.7542 | Yes |
| 34 | LDHA | lactate dehydrogenase A [Source:HGNC Symbol;Acc:HGNC:6535] | 34313 | -1.221 | -0.7443 | Yes |
| 35 | FAM83D | family with sequence similarity 83 member D [Source:HGNC Symbol;Acc:HGNC:16122] | 34349 | -1.234 | -0.7342 | Yes |
| 36 | CIT | citron rho-interacting serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1985] | 34537 | -1.308 | -0.7274 | Yes |
| 37 | MIS18BP1 | MIS18 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:20190] | 34784 | -1.411 | -0.7214 | Yes |
| 38 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34791 | -1.414 | -0.7088 | Yes |
| 39 | PRR11 | proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] | 34834 | -1.438 | -0.6970 | Yes |
| 40 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 34837 | -1.440 | -0.6840 | Yes |
| 41 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 34877 | -1.459 | -0.6720 | Yes |
| 42 | NDE1 | nudE neurodevelopment protein 1 [Source:HGNC Symbol;Acc:HGNC:17619] | 34911 | -1.475 | -0.6596 | Yes |
| 43 | TUBA1C | tubulin alpha 1c [Source:HGNC Symbol;Acc:HGNC:20768] | 35017 | -1.527 | -0.6486 | Yes |
| 44 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 35249 | -1.649 | -0.6400 | Yes |
| 45 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 35259 | -1.656 | -0.6254 | Yes |
| 46 | MZT1 | mitotic spindle organizing protein 1 [Source:HGNC Symbol;Acc:HGNC:33830] | 35397 | -1.730 | -0.6135 | Yes |
| 47 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 35419 | -1.743 | -0.5983 | Yes |
| 48 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35520 | -1.803 | -0.5848 | Yes |
| 49 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 35561 | -1.824 | -0.5694 | Yes |
| 50 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35605 | -1.855 | -0.5539 | Yes |
| 51 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35626 | -1.864 | -0.5376 | Yes |
| 52 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35787 | -1.989 | -0.5240 | Yes |
| 53 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 35841 | -2.029 | -0.5072 | Yes |
| 54 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 35900 | -2.083 | -0.4900 | Yes |
| 55 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36013 | -2.163 | -0.4735 | Yes |
| 56 | CEP70 | centrosomal protein 70 [Source:HGNC Symbol;Acc:HGNC:29972] | 36035 | -2.183 | -0.4544 | Yes |
| 57 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36153 | -2.285 | -0.4370 | Yes |
| 58 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36160 | -2.294 | -0.4165 | Yes |
| 59 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36192 | -2.319 | -0.3964 | Yes |
| 60 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36214 | -2.336 | -0.3760 | Yes |
| 61 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36276 | -2.406 | -0.3559 | Yes |
| 62 | PHF19 | PHD finger protein 19 [Source:HGNC Symbol;Acc:HGNC:24566] | 36300 | -2.429 | -0.3347 | Yes |
| 63 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36323 | -2.449 | -0.3132 | Yes |
| 64 | SPDL1 | spindle apparatus coiled-coil protein 1 [Source:HGNC Symbol;Acc:HGNC:26010] | 36351 | -2.483 | -0.2916 | Yes |
| 65 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36364 | -2.499 | -0.2694 | Yes |
| 66 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 36372 | -2.507 | -0.2470 | Yes |
| 67 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36393 | -2.540 | -0.2246 | Yes |
| 68 | CDCA2 | cell division cycle associated 2 [Source:HGNC Symbol;Acc:HGNC:14623] | 36433 | -2.595 | -0.2023 | Yes |
| 69 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36453 | -2.630 | -0.1791 | Yes |
| 70 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 36576 | -2.796 | -0.1572 | Yes |
| 71 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36589 | -2.814 | -0.1322 | Yes |
| 72 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36625 | -2.872 | -0.1073 | Yes |
| 73 | KNSTRN | kinetochore localized astrin (SPAG5) binding protein [Source:HGNC Symbol;Acc:HGNC:30767] | 36672 | -2.949 | -0.0820 | Yes |
| 74 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36673 | -2.950 | -0.0554 | Yes |
| 75 | NEIL3 | nei like DNA glycosylase 3 [Source:HGNC Symbol;Acc:HGNC:24573] | 36877 | -3.375 | -0.0305 | Yes |
| 76 | PSRC1 | proline and serine rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:24472] | 37027 | -4.019 | 0.0017 | Yes |
