Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | ZHONG_PFC_C8_ORG_PROLIFERATING |
| Enrichment Score (ES) | -0.7937675 |
| Normalized Enrichment Score (NES) | -1.5940709 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0030701242 |
| FWER p-Value | 0.054 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MT2A | metallothionein 2A [Source:HGNC Symbol;Acc:HGNC:7406] | 893 | 1.532 | -0.0069 | No |
| 2 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1757 | 1.003 | -0.0190 | No |
| 3 | EMP3 | epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335] | 1903 | 0.944 | -0.0123 | No |
| 4 | TUBB6 | tubulin beta 6 class V [Source:HGNC Symbol;Acc:HGNC:20776] | 4617 | 0.292 | -0.0823 | No |
| 5 | GAS2L3 | growth arrest specific 2 like 3 [Source:HGNC Symbol;Acc:HGNC:27475] | 5144 | 0.210 | -0.0941 | No |
| 6 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 5637 | 0.136 | -0.1059 | No |
| 7 | CCNA1 | cyclin A1 [Source:HGNC Symbol;Acc:HGNC:1577] | 7918 | 0.000 | -0.1675 | No |
| 8 | NMU | neuromedin U [Source:HGNC Symbol;Acc:HGNC:7859] | 19313 | 0.000 | -0.4752 | No |
| 9 | SFRP2 | secreted frizzled related protein 2 [Source:HGNC Symbol;Acc:HGNC:10777] | 23636 | 0.000 | -0.5919 | No |
| 10 | CRNDE | colorectal neoplasia differentially expressed [Source:HGNC Symbol;Acc:HGNC:37078] | 28012 | -0.069 | -0.7093 | No |
| 11 | UNC50 | unc-50 inner nuclear membrane RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16046] | 29431 | -0.242 | -0.7448 | No |
| 12 | NOTCH2NLA | notch 2 N-terminal like A [Source:HGNC Symbol;Acc:HGNC:31862] | 29531 | -0.257 | -0.7446 | No |
| 13 | ITGB1BP1 | integrin subunit beta 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23927] | 29575 | -0.263 | -0.7428 | No |
| 14 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 29922 | -0.301 | -0.7488 | No |
| 15 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 30362 | -0.359 | -0.7566 | No |
| 16 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31738 | -0.568 | -0.7874 | Yes |
| 17 | TXNDC12 | thioredoxin domain containing 12 [Source:HGNC Symbol;Acc:HGNC:24626] | 31909 | -0.595 | -0.7853 | Yes |
| 18 | TROAP | trophinin associated protein [Source:HGNC Symbol;Acc:HGNC:12327] | 32139 | -0.639 | -0.7843 | Yes |
| 19 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 32260 | -0.666 | -0.7801 | Yes |
| 20 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 32450 | -0.711 | -0.7772 | Yes |
| 21 | HSD17B11 | hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960] | 32512 | -0.724 | -0.7707 | Yes |
| 22 | ANXA2 | annexin A2 [Source:HGNC Symbol;Acc:HGNC:537] | 32754 | -0.781 | -0.7685 | Yes |
| 23 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33320 | -0.929 | -0.7733 | Yes |
| 24 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 33672 | -1.025 | -0.7713 | Yes |
| 25 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 33831 | -1.063 | -0.7636 | Yes |
| 26 | ARL6IP1 | ADP ribosylation factor like GTPase 6 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:697] | 33946 | -1.095 | -0.7544 | Yes |
| 27 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 34058 | -1.132 | -0.7447 | Yes |
| 28 | LGALS1 | galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561] | 34169 | -1.167 | -0.7345 | Yes |
| 29 | TMEM256 | transmembrane protein 256 [Source:HGNC Symbol;Acc:HGNC:28618] | 34358 | -1.236 | -0.7258 | Yes |
| 30 | ODF2 | outer dense fiber of sperm tails 2 [Source:HGNC Symbol;Acc:HGNC:8114] | 34740 | -1.395 | -0.7204 | Yes |
| 31 | PRR11 | proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] | 34834 | -1.438 | -0.7068 | Yes |
| 32 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 34837 | -1.440 | -0.6906 | Yes |
| 33 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 34877 | -1.459 | -0.6753 | Yes |
| 34 | TUBA1C | tubulin alpha 1c [Source:HGNC Symbol;Acc:HGNC:20768] | 35017 | -1.527 | -0.6619 | Yes |
| 35 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35050 | -1.543 | -0.6455 | Yes |
| 36 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35085 | -1.562 | -0.6289 | Yes |
| 37 | KIF18A | kinesin family member 18A [Source:HGNC Symbol;Acc:HGNC:29441] | 35217 | -1.634 | -0.6141 | Yes |
| 38 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35320 | -1.686 | -0.5979 | Yes |
| 39 | MZT1 | mitotic spindle organizing protein 1 [Source:HGNC Symbol;Acc:HGNC:33830] | 35397 | -1.730 | -0.5805 | Yes |
| 40 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 35551 | -1.818 | -0.5642 | Yes |
| 41 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35605 | -1.855 | -0.5449 | Yes |
| 42 | CRYZ | crystallin zeta [Source:HGNC Symbol;Acc:HGNC:2419] | 35636 | -1.876 | -0.5246 | Yes |
| 43 | PLIN3 | perilipin 3 [Source:HGNC Symbol;Acc:HGNC:16893] | 35737 | -1.950 | -0.5054 | Yes |
| 44 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35787 | -1.989 | -0.4844 | Yes |
| 45 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 35841 | -2.029 | -0.4631 | Yes |
| 46 | CEP70 | centrosomal protein 70 [Source:HGNC Symbol;Acc:HGNC:29972] | 36035 | -2.183 | -0.4438 | Yes |
| 47 | CKAP2 | cytoskeleton associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1990] | 36065 | -2.205 | -0.4198 | Yes |
| 48 | CCDC34 | coiled-coil domain containing 34 [Source:HGNC Symbol;Acc:HGNC:25079] | 36072 | -2.209 | -0.3952 | Yes |
| 49 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36101 | -2.242 | -0.3708 | Yes |
| 50 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36160 | -2.294 | -0.3466 | Yes |
| 51 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36214 | -2.336 | -0.3218 | Yes |
| 52 | RP2 | RP2 activator of ARL3 GTPase [Source:HGNC Symbol;Acc:HGNC:10274] | 36263 | -2.396 | -0.2962 | Yes |
| 53 | DEPDC1B | DEP domain containing 1B [Source:HGNC Symbol;Acc:HGNC:24902] | 36275 | -2.406 | -0.2695 | Yes |
| 54 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36276 | -2.406 | -0.2425 | Yes |
| 55 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 36372 | -2.507 | -0.2169 | Yes |
| 56 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36393 | -2.540 | -0.1889 | Yes |
| 57 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36453 | -2.630 | -0.1610 | Yes |
| 58 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 36576 | -2.796 | -0.1329 | Yes |
| 59 | KNSTRN | kinetochore localized astrin (SPAG5) binding protein [Source:HGNC Symbol;Acc:HGNC:30767] | 36672 | -2.949 | -0.1024 | Yes |
| 60 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36673 | -2.950 | -0.0693 | Yes |
| 61 | SMTN | smoothelin [Source:HGNC Symbol;Acc:HGNC:11126] | 36780 | -3.151 | -0.0368 | Yes |
| 62 | PSRC1 | proline and serine rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:24472] | 37027 | -4.019 | 0.0017 | Yes |
