Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | HALLMARK_ANGIOGENESIS |
| Enrichment Score (ES) | 0.5510043 |
| Normalized Enrichment Score (NES) | 1.1846743 |
| Nominal p-value | 0.16260162 |
| FDR q-value | 0.14028566 |
| FWER p-Value | 0.426 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SPP1 | secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255] | 136 | 3.345 | 0.1326 | Yes |
| 2 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 172 | 3.156 | 0.2602 | Yes |
| 3 | ITGAV | integrin subunit alpha V [Source:HGNC Symbol;Acc:HGNC:6150] | 264 | 2.714 | 0.3683 | Yes |
| 4 | CCND2 | cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583] | 686 | 1.780 | 0.4295 | Yes |
| 5 | LPL | lipoprotein lipase [Source:HGNC Symbol;Acc:HGNC:6677] | 719 | 1.722 | 0.4987 | Yes |
| 6 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 972 | 1.450 | 0.5510 | Yes |
| 7 | PTK2 | protein tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:9611] | 3916 | 0.404 | 0.4880 | No |
| 8 | FGFR1 | fibroblast growth factor receptor 1 [Source:HGNC Symbol;Acc:HGNC:3688] | 4566 | 0.299 | 0.4827 | No |
| 9 | LRPAP1 | LDL receptor related protein associated protein 1 [Source:HGNC Symbol;Acc:HGNC:6701] | 6182 | 0.066 | 0.4418 | No |
| 10 | APOH | apolipoprotein H [Source:HGNC Symbol;Acc:HGNC:616] | 7199 | 0.000 | 0.4144 | No |
| 11 | TNFRSF21 | TNF receptor superfamily member 21 [Source:HGNC Symbol;Acc:HGNC:13469] | 9565 | 0.000 | 0.3505 | No |
| 12 | KCNJ8 | potassium inwardly rectifying channel subfamily J member 8 [Source:HGNC Symbol;Acc:HGNC:6269] | 10143 | 0.000 | 0.3350 | No |
| 13 | POSTN | periostin [Source:HGNC Symbol;Acc:HGNC:16953] | 10547 | 0.000 | 0.3241 | No |
| 14 | PRG2 | proteoglycan 2, pro eosinophil major basic protein [Source:HGNC Symbol;Acc:HGNC:9362] | 11779 | 0.000 | 0.2909 | No |
| 15 | MSX1 | msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391] | 12742 | 0.000 | 0.2649 | No |
| 16 | VTN | vitronectin [Source:HGNC Symbol;Acc:HGNC:12724] | 13490 | 0.000 | 0.2447 | No |
| 17 | OLR1 | oxidized low density lipoprotein receptor 1 [Source:HGNC Symbol;Acc:HGNC:8133] | 16808 | 0.000 | 0.1552 | No |
| 18 | SERPINA5 | serpin family A member 5 [Source:HGNC Symbol;Acc:HGNC:8723] | 17819 | 0.000 | 0.1280 | No |
| 19 | LUM | lumican [Source:HGNC Symbol;Acc:HGNC:6724] | 18761 | 0.000 | 0.1026 | No |
| 20 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19425 | 0.000 | 0.0847 | No |
| 21 | PF4 | platelet factor 4 [Source:HGNC Symbol;Acc:HGNC:8861] | 19955 | 0.000 | 0.0704 | No |
| 22 | PGLYRP1 | peptidoglycan recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:8904] | 20787 | 0.000 | 0.0480 | No |
| 23 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 21359 | 0.000 | 0.0326 | No |
| 24 | SLCO2A1 | solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955] | 26608 | 0.000 | -0.1091 | No |
| 25 | APP | amyloid beta precursor protein [Source:HGNC Symbol;Acc:HGNC:620] | 27669 | -0.030 | -0.1364 | No |
| 26 | THBD | thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784] | 27809 | -0.047 | -0.1383 | No |
| 27 | COL5A2 | collagen type V alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2210] | 28104 | -0.081 | -0.1429 | No |
| 28 | COL3A1 | collagen type III alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2201] | 28182 | -0.092 | -0.1412 | No |
| 29 | STC1 | stanniocalcin 1 [Source:HGNC Symbol;Acc:HGNC:11373] | 28490 | -0.129 | -0.1443 | No |
| 30 | VEGFA | vascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680] | 28797 | -0.162 | -0.1459 | No |
| 31 | VCAN | versican [Source:HGNC Symbol;Acc:HGNC:2464] | 30920 | -0.440 | -0.1853 | No |
| 32 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 31262 | -0.494 | -0.1743 | No |
| 33 | VAV2 | vav guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:12658] | 32107 | -0.632 | -0.1713 | No |
| 34 | JAG1 | jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188] | 35522 | -1.803 | -0.1900 | No |
| 35 | NRP1 | neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004] | 36356 | -2.490 | -0.1111 | No |
| 36 | JAG2 | jagged canonical Notch ligand 2 [Source:HGNC Symbol;Acc:HGNC:6189] | 36814 | -3.212 | 0.0074 | No |
