Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | HALLMARK_CHOLESTEROL_HOMEOSTASIS |
| Enrichment Score (ES) | -0.5126668 |
| Normalized Enrichment Score (NES) | -1.0530665 |
| Nominal p-value | 0.3721212 |
| FDR q-value | 0.66600704 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ERRFI1 | ERBB receptor feedback inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:18185] | 153 | 3.258 | 0.0305 | No |
| 2 | ACTG1 | actin gamma 1 [Source:HGNC Symbol;Acc:HGNC:144] | 204 | 3.029 | 0.0614 | No |
| 3 | S100A11 | S100 calcium binding protein A11 [Source:HGNC Symbol;Acc:HGNC:10488] | 411 | 2.327 | 0.0806 | No |
| 4 | ATF3 | activating transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:785] | 496 | 2.102 | 0.1007 | No |
| 5 | ATF5 | activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790] | 610 | 1.899 | 0.1178 | No |
| 6 | CD9 | CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709] | 709 | 1.741 | 0.1337 | No |
| 7 | LPL | lipoprotein lipase [Source:HGNC Symbol;Acc:HGNC:6677] | 719 | 1.722 | 0.1518 | No |
| 8 | TNFRSF12A | TNF receptor superfamily member 12A [Source:HGNC Symbol;Acc:HGNC:18152] | 757 | 1.678 | 0.1686 | No |
| 9 | CHKA | choline kinase alpha [Source:HGNC Symbol;Acc:HGNC:1937] | 823 | 1.600 | 0.1839 | No |
| 10 | ALCAM | activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400] | 933 | 1.494 | 0.1968 | No |
| 11 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 981 | 1.443 | 0.2109 | No |
| 12 | HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:5006] | 1164 | 1.314 | 0.2200 | No |
| 13 | LDLR | low density lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:6547] | 1805 | 0.984 | 0.2131 | No |
| 14 | ANTXR2 | ANTXR cell adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:21732] | 1806 | 0.983 | 0.2236 | No |
| 15 | GLDC | glycine decarboxylase [Source:HGNC Symbol;Acc:HGNC:4313] | 1855 | 0.965 | 0.2326 | No |
| 16 | TRIB3 | tribbles pseudokinase 3 [Source:HGNC Symbol;Acc:HGNC:16228] | 1981 | 0.907 | 0.2388 | No |
| 17 | GNAI1 | G protein subunit alpha i1 [Source:HGNC Symbol;Acc:HGNC:4384] | 2109 | 0.853 | 0.2445 | No |
| 18 | ANXA5 | annexin A5 [Source:HGNC Symbol;Acc:HGNC:543] | 2569 | 0.702 | 0.2395 | No |
| 19 | HSD17B7 | hydroxysteroid 17-beta dehydrogenase 7 [Source:HGNC Symbol;Acc:HGNC:5215] | 2881 | 0.617 | 0.2377 | No |
| 20 | PPARG | peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236] | 3003 | 0.589 | 0.2407 | No |
| 21 | NFIL3 | nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:HGNC:7787] | 3427 | 0.494 | 0.2345 | No |
| 22 | CTNNB1 | catenin beta 1 [Source:HGNC Symbol;Acc:HGNC:2514] | 4451 | 0.316 | 0.2103 | No |
| 23 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 4730 | 0.275 | 0.2057 | No |
| 24 | CYP51A1 | cytochrome P450 family 51 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2649] | 4873 | 0.251 | 0.2045 | No |
| 25 | IDI1 | isopentenyl-diphosphate delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:5387] | 6112 | 0.076 | 0.1719 | No |
| 26 | TMEM97 | transmembrane protein 97 [Source:HGNC Symbol;Acc:HGNC:28106] | 6397 | 0.039 | 0.1646 | No |
| 27 | FBXO6 | F-box protein 6 [Source:HGNC Symbol;Acc:HGNC:13585] | 7187 | 0.000 | 0.1433 | No |
| 28 | GPX8 | glutathione peroxidase 8 (putative) [Source:HGNC Symbol;Acc:HGNC:33100] | 9808 | 0.000 | 0.0725 | No |
| 29 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9978 | 0.000 | 0.0680 | No |
| 30 | ADH4 | alcohol dehydrogenase 4 (class II), pi polypeptide [Source:HGNC Symbol;Acc:HGNC:252] | 11386 | 0.000 | 0.0300 | No |
| 31 | ANXA13 | annexin A13 [Source:HGNC Symbol;Acc:HGNC:536] | 14484 | 0.000 | -0.0537 | No |
| 32 | AVPR1A | arginine vasopressin receptor 1A [Source:HGNC Symbol;Acc:HGNC:895] | 16707 | 0.000 | -0.1137 | No |
| 33 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 18875 | 0.000 | -0.1723 | No |
| 34 | PLAUR | plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:HGNC:9053] | 25686 | 0.000 | -0.3562 | No |
| 35 | MAL2 | mal, T cell differentiation protein 2 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:13634] | 27307 | 0.000 | -0.4000 | No |
| 36 | SEMA3B | semaphorin 3B [Source:HGNC Symbol;Acc:HGNC:10724] | 28286 | -0.106 | -0.4253 | No |
| 37 | FASN | fatty acid synthase [Source:HGNC Symbol;Acc:HGNC:3594] | 28611 | -0.141 | -0.4326 | No |
| 38 | GUSB | glucuronidase beta [Source:HGNC Symbol;Acc:HGNC:4696] | 29751 | -0.282 | -0.4603 | No |
| 39 | SC5D | sterol-C5-desaturase [Source:HGNC Symbol;Acc:HGNC:10547] | 31541 | -0.538 | -0.5029 | No |
| 40 | CPEB2 | cytoplasmic polyadenylation element binding protein 2 [Source:HGNC Symbol;Acc:HGNC:21745] | 31902 | -0.593 | -0.5064 | Yes |
| 41 | NIBAN1 | niban apoptosis regulator 1 [Source:HGNC Symbol;Acc:HGNC:16784] | 31931 | -0.599 | -0.5007 | Yes |
| 42 | FABP5 | fatty acid binding protein 5 [Source:HGNC Symbol;Acc:HGNC:3560] | 31974 | -0.609 | -0.4954 | Yes |
| 43 | SQLE | squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279] | 32039 | -0.622 | -0.4905 | Yes |
| 44 | STX5 | syntaxin 5 [Source:HGNC Symbol;Acc:HGNC:11440] | 32366 | -0.692 | -0.4920 | Yes |
| 45 | HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 [Source:HGNC Symbol;Acc:HGNC:5007] | 32513 | -0.725 | -0.4882 | Yes |
| 46 | PMVK | phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141] | 32578 | -0.739 | -0.4821 | Yes |
| 47 | STARD4 | StAR related lipid transfer domain containing 4 [Source:HGNC Symbol;Acc:HGNC:18058] | 32742 | -0.778 | -0.4782 | Yes |
| 48 | MVK | mevalonate kinase [Source:HGNC Symbol;Acc:HGNC:7530] | 32831 | -0.800 | -0.4721 | Yes |
| 49 | LSS | lanosterol synthase [Source:HGNC Symbol;Acc:HGNC:6708] | 32834 | -0.800 | -0.4636 | Yes |
| 50 | ATXN2 | ataxin 2 [Source:HGNC Symbol;Acc:HGNC:10555] | 33345 | -0.934 | -0.4674 | Yes |
| 51 | SREBF2 | sterol regulatory element binding transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11290] | 33418 | -0.952 | -0.4592 | Yes |
| 52 | FDFT1 | farnesyl-diphosphate farnesyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:3629] | 34144 | -1.159 | -0.4665 | Yes |
| 53 | FDPS | farnesyl diphosphate synthase [Source:HGNC Symbol;Acc:HGNC:3631] | 34580 | -1.326 | -0.4642 | Yes |
| 54 | NSDHL | NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398] | 34776 | -1.408 | -0.4544 | Yes |
| 55 | PDK3 | pyruvate dehydrogenase kinase 3 [Source:HGNC Symbol;Acc:HGNC:8811] | 35007 | -1.521 | -0.4445 | Yes |
| 56 | CBS | cystathionine beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550] | 35042 | -1.539 | -0.4290 | Yes |
| 57 | LGALS3 | galectin 3 [Source:HGNC Symbol;Acc:HGNC:6563] | 35297 | -1.674 | -0.4181 | Yes |
| 58 | EBP | EBP cholestenol delta-isomerase [Source:HGNC Symbol;Acc:HGNC:3133] | 35416 | -1.741 | -0.4027 | Yes |
| 59 | JAG1 | jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188] | 35522 | -1.803 | -0.3864 | Yes |
| 60 | ALDOC | aldolase, fructose-bisphosphate C [Source:HGNC Symbol;Acc:HGNC:418] | 35692 | -1.920 | -0.3705 | Yes |
| 61 | ABCA2 | ATP binding cassette subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:32] | 35882 | -2.064 | -0.3537 | Yes |
| 62 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 35984 | -2.141 | -0.3336 | Yes |
| 63 | PCYT2 | phosphate cytidylyltransferase 2, ethanolamine [Source:HGNC Symbol;Acc:HGNC:8756] | 35986 | -2.143 | -0.3109 | Yes |
| 64 | ETHE1 | ETHE1 persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287] | 36229 | -2.350 | -0.2924 | Yes |
| 65 | ACAT2 | acetyl-CoA acetyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:94] | 36271 | -2.402 | -0.2680 | Yes |
| 66 | FADS2 | fatty acid desaturase 2 [Source:HGNC Symbol;Acc:HGNC:3575] | 36326 | -2.453 | -0.2433 | Yes |
| 67 | MVD | mevalonate diphosphate decarboxylase [Source:HGNC Symbol;Acc:HGNC:7529] | 36400 | -2.546 | -0.2182 | Yes |
| 68 | ECH1 | enoyl-CoA hydratase 1 [Source:HGNC Symbol;Acc:HGNC:3149] | 36596 | -2.823 | -0.1935 | Yes |
| 69 | TP53INP1 | tumor protein p53 inducible nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:18022] | 36654 | -2.909 | -0.1641 | Yes |
| 70 | DHCR7 | 7-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2860] | 36693 | -2.986 | -0.1333 | Yes |
| 71 | TM7SF2 | transmembrane 7 superfamily member 2 [Source:HGNC Symbol;Acc:HGNC:11863] | 36733 | -3.055 | -0.1019 | Yes |
| 72 | PNRC1 | proline rich nuclear receptor coactivator 1 [Source:HGNC Symbol;Acc:HGNC:17278] | 36804 | -3.188 | -0.0699 | Yes |
| 73 | ACSS2 | acyl-CoA synthetase short chain family member 2 [Source:HGNC Symbol;Acc:HGNC:15814] | 36887 | -3.410 | -0.0358 | Yes |
| 74 | SCD | stearoyl-CoA desaturase [Source:HGNC Symbol;Acc:HGNC:10571] | 37001 | -3.880 | 0.0024 | Yes |
