Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | HALLMARK_INTERFERON_ALPHA_RESPONSE |
| Enrichment Score (ES) | 0.77479327 |
| Normalized Enrichment Score (NES) | 1.9389359 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 37 | 4.297 | 0.0277 | Yes |
| 2 | OASL | 2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] | 48 | 4.133 | 0.0551 | Yes |
| 3 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 53 | 4.050 | 0.0820 | Yes |
| 4 | DHX58 | DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517] | 63 | 3.992 | 0.1085 | Yes |
| 5 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 77 | 3.799 | 0.1335 | Yes |
| 6 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 85 | 3.724 | 0.1582 | Yes |
| 7 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 86 | 3.723 | 0.1831 | Yes |
| 8 | TRAFD1 | TRAF-type zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24808] | 92 | 3.659 | 0.2074 | Yes |
| 9 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [Source:HGNC Symbol;Acc:HGNC:26072] | 93 | 3.654 | 0.2318 | Yes |
| 10 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 101 | 3.606 | 0.2557 | Yes |
| 11 | IFIH1 | interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873] | 126 | 3.418 | 0.2779 | Yes |
| 12 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 133 | 3.364 | 0.3002 | Yes |
| 13 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 143 | 3.299 | 0.3220 | Yes |
| 14 | ISG20 | interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] | 155 | 3.255 | 0.3435 | Yes |
| 15 | PARP12 | poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919] | 184 | 3.113 | 0.3635 | Yes |
| 16 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 220 | 2.934 | 0.3822 | Yes |
| 17 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 246 | 2.791 | 0.4002 | Yes |
| 18 | GBP4 | guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480] | 274 | 2.682 | 0.4174 | Yes |
| 19 | EPSTI1 | epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] | 281 | 2.657 | 0.4349 | Yes |
| 20 | SAMD9 | sterile alpha motif domain containing 9 [Source:HGNC Symbol;Acc:HGNC:1348] | 285 | 2.640 | 0.4525 | Yes |
| 21 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 317 | 2.547 | 0.4687 | Yes |
| 22 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 358 | 2.459 | 0.4840 | Yes |
| 23 | TRIM25 | tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932] | 364 | 2.441 | 0.5002 | Yes |
| 24 | PNPT1 | polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166] | 395 | 2.373 | 0.5153 | Yes |
| 25 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 397 | 2.367 | 0.5311 | Yes |
| 26 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 467 | 2.166 | 0.5437 | Yes |
| 27 | ADAR | adenosine deaminase RNA specific [Source:HGNC Symbol;Acc:HGNC:225] | 469 | 2.163 | 0.5581 | Yes |
| 28 | TRIM21 | tripartite motif containing 21 [Source:HGNC Symbol;Acc:HGNC:11312] | 474 | 2.153 | 0.5724 | Yes |
| 29 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 491 | 2.110 | 0.5860 | Yes |
| 30 | IFITM2 | interferon induced transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:5413] | 510 | 2.076 | 0.5994 | Yes |
| 31 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 533 | 2.033 | 0.6124 | Yes |
| 32 | IRF9 | interferon regulatory factor 9 [Source:HGNC Symbol;Acc:HGNC:6131] | 553 | 1.992 | 0.6252 | Yes |
| 33 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 557 | 1.990 | 0.6384 | Yes |
| 34 | PROCR | protein C receptor [Source:HGNC Symbol;Acc:HGNC:9452] | 567 | 1.978 | 0.6514 | Yes |
| 35 | OGFR | opioid growth factor receptor [Source:HGNC Symbol;Acc:HGNC:15768] | 603 | 1.914 | 0.6632 | Yes |
| 36 | PARP9 | poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118] | 615 | 1.895 | 0.6756 | Yes |
| 37 | UBA7 | ubiquitin like modifier activating enzyme 7 [Source:HGNC Symbol;Acc:HGNC:12471] | 623 | 1.886 | 0.6880 | Yes |
| 38 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 755 | 1.679 | 0.6957 | Yes |
| 39 | CMTR1 | cap methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:21077] | 788 | 1.640 | 0.7058 | Yes |
| 40 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 871 | 1.549 | 0.7139 | Yes |
| 41 | MOV10 | Mov10 RISC complex RNA helicase [Source:HGNC Symbol;Acc:HGNC:7200] | 899 | 1.527 | 0.7234 | Yes |
| 42 | TDRD7 | tudor domain containing 7 [Source:HGNC Symbol;Acc:HGNC:30831] | 1005 | 1.424 | 0.7301 | Yes |
| 43 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 1007 | 1.423 | 0.7396 | Yes |
| 44 | TRIM26 | tripartite motif containing 26 [Source:HGNC Symbol;Acc:HGNC:12962] | 1117 | 1.351 | 0.7456 | Yes |
| 45 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 1308 | 1.207 | 0.7486 | Yes |
| 46 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 1404 | 1.146 | 0.7537 | Yes |
| 47 | UBE2L6 | ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490] | 1406 | 1.146 | 0.7613 | Yes |
| 48 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 1571 | 1.078 | 0.7641 | Yes |
| 49 | PSMA3 | proteasome 20S subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:9532] | 1864 | 0.962 | 0.7626 | Yes |
| 50 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 1993 | 0.902 | 0.7652 | Yes |
| 51 | CASP8 | caspase 8 [Source:HGNC Symbol;Acc:HGNC:1509] | 1997 | 0.900 | 0.7711 | Yes |
| 52 | CD47 | CD47 molecule [Source:HGNC Symbol;Acc:HGNC:1682] | 2078 | 0.867 | 0.7747 | Yes |
| 53 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 2405 | 0.750 | 0.7709 | Yes |
| 54 | PSMB8 | proteasome 20S subunit beta 8 [Source:HGNC Symbol;Acc:HGNC:9545] | 2453 | 0.737 | 0.7746 | Yes |
| 55 | CASP1 | caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499] | 2817 | 0.632 | 0.7690 | Yes |
| 56 | TRIM14 | tripartite motif containing 14 [Source:HGNC Symbol;Acc:HGNC:16283] | 2885 | 0.616 | 0.7713 | Yes |
| 57 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 2954 | 0.600 | 0.7735 | Yes |
| 58 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 3194 | 0.547 | 0.7707 | Yes |
| 59 | SP110 | SP110 nuclear body protein [Source:HGNC Symbol;Acc:HGNC:5401] | 3221 | 0.539 | 0.7736 | Yes |
| 60 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 3306 | 0.522 | 0.7748 | Yes |
| 61 | TRIM5 | tripartite motif containing 5 [Source:HGNC Symbol;Acc:HGNC:16276] | 3652 | 0.450 | 0.7685 | No |
| 62 | LAP3 | leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] | 3705 | 0.440 | 0.7700 | No |
| 63 | WARS1 | tryptophanyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12729] | 3863 | 0.413 | 0.7685 | No |
| 64 | TENT5A | terminal nucleotidyltransferase 5A [Source:HGNC Symbol;Acc:HGNC:18345] | 3985 | 0.392 | 0.7679 | No |
| 65 | B2M | beta-2-microglobulin [Source:HGNC Symbol;Acc:HGNC:914] | 4373 | 0.327 | 0.7596 | No |
| 66 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 4423 | 0.319 | 0.7604 | No |
| 67 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 4730 | 0.275 | 0.7540 | No |
| 68 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 4881 | 0.250 | 0.7516 | No |
| 69 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 6039 | 0.084 | 0.7209 | No |
| 70 | SELL | selectin L [Source:HGNC Symbol;Acc:HGNC:10720] | 7522 | 0.000 | 0.6808 | No |
| 71 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 9070 | 0.000 | 0.6390 | No |
| 72 | BATF2 | basic leucine zipper ATF-like transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:25163] | 9186 | 0.000 | 0.6359 | No |
| 73 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 9525 | 0.000 | 0.6268 | No |
| 74 | RTP4 | receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992] | 10801 | 0.000 | 0.5923 | No |
| 75 | IFI30 | IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398] | 11754 | 0.000 | 0.5666 | No |
| 76 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12704 | 0.000 | 0.5409 | No |
| 77 | IL4R | interleukin 4 receptor [Source:HGNC Symbol;Acc:HGNC:6015] | 14056 | 0.000 | 0.5044 | No |
| 78 | IL7 | interleukin 7 [Source:HGNC Symbol;Acc:HGNC:6023] | 17753 | 0.000 | 0.4045 | No |
| 79 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18909 | 0.000 | 0.3733 | No |
| 80 | NMI | N-myc and STAT interactor [Source:HGNC Symbol;Acc:HGNC:7854] | 19308 | 0.000 | 0.3625 | No |
| 81 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 24539 | 0.000 | 0.2211 | No |
| 82 | NCOA7 | nuclear receptor coactivator 7 [Source:HGNC Symbol;Acc:HGNC:21081] | 27555 | -0.014 | 0.1397 | No |
| 83 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 29711 | -0.279 | 0.0833 | No |
| 84 | PSMB9 | proteasome 20S subunit beta 9 [Source:HGNC Symbol;Acc:HGNC:9546] | 29896 | -0.298 | 0.0804 | No |
| 85 | C1S | complement C1s [Source:HGNC Symbol;Acc:HGNC:1247] | 30184 | -0.335 | 0.0748 | No |
| 86 | IRF1 | interferon regulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:6116] | 31490 | -0.528 | 0.0431 | No |
| 87 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 32280 | -0.671 | 0.0262 | No |
| 88 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 32838 | -0.801 | 0.0165 | No |
| 89 | ELF1 | E74 like ETS transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3316] | 33062 | -0.858 | 0.0162 | No |
| 90 | SLC25A28 | solute carrier family 25 member 28 [Source:HGNC Symbol;Acc:HGNC:23472] | 33270 | -0.914 | 0.0168 | No |
| 91 | NUB1 | negative regulator of ubiquitin like proteins 1 [Source:HGNC Symbol;Acc:HGNC:17623] | 33835 | -1.064 | 0.0086 | No |
| 92 | IRF2 | interferon regulatory factor 2 [Source:HGNC Symbol;Acc:HGNC:6117] | 34229 | -1.191 | 0.0060 | No |
| 93 | MVB12A | multivesicular body subunit 12A [Source:HGNC Symbol;Acc:HGNC:25153] | 34417 | -1.256 | 0.0093 | No |
| 94 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 34633 | -1.342 | 0.0124 | No |
| 95 | CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase [Source:HGNC Symbol;Acc:HGNC:2158] | 36088 | -2.229 | -0.0120 | No |
| 96 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 36209 | -2.333 | 0.0004 | No |
| 97 | GMPR | guanosine monophosphate reductase [Source:HGNC Symbol;Acc:HGNC:4376] | 36901 | -3.502 | 0.0051 | No |
