Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | HALLMARK_MYC_TARGETS_V2 |
| Enrichment Score (ES) | 0.5828758 |
| Normalized Enrichment Score (NES) | 1.3910378 |
| Nominal p-value | 0.018867925 |
| FDR q-value | 0.02926074 |
| FWER p-Value | 0.097 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 30 | 4.483 | 0.0587 | Yes |
| 2 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 94 | 3.654 | 0.1055 | Yes |
| 3 | GRWD1 | glutamate rich WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:21270] | 293 | 2.620 | 0.1350 | Yes |
| 4 | IPO4 | importin 4 [Source:HGNC Symbol;Acc:HGNC:19426] | 341 | 2.489 | 0.1667 | Yes |
| 5 | RRP9 | ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16829] | 401 | 2.357 | 0.1964 | Yes |
| 6 | NOP2 | NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867] | 506 | 2.082 | 0.2213 | Yes |
| 7 | RRP12 | ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100] | 516 | 2.054 | 0.2483 | Yes |
| 8 | UTP20 | UTP20 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:17897] | 529 | 2.034 | 0.2750 | Yes |
| 9 | NIP7 | nucleolar pre-rRNA processing protein NIP7 [Source:HGNC Symbol;Acc:HGNC:24328] | 559 | 1.986 | 0.3006 | Yes |
| 10 | NOP16 | NOP16 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:26934] | 656 | 1.813 | 0.3221 | Yes |
| 11 | MYBBP1A | MYB binding protein 1a [Source:HGNC Symbol;Acc:HGNC:7546] | 891 | 1.535 | 0.3361 | Yes |
| 12 | MRTO4 | MRT4 homolog, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:18477] | 900 | 1.527 | 0.3562 | Yes |
| 13 | BYSL | bystin like [Source:HGNC Symbol;Acc:HGNC:1157] | 950 | 1.477 | 0.3745 | Yes |
| 14 | HK2 | hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923] | 1013 | 1.421 | 0.3917 | Yes |
| 15 | DDX18 | DEAD-box helicase 18 [Source:HGNC Symbol;Acc:HGNC:2741] | 1202 | 1.288 | 0.4037 | Yes |
| 16 | WDR43 | WD repeat domain 43 [Source:HGNC Symbol;Acc:HGNC:28945] | 1242 | 1.257 | 0.4193 | Yes |
| 17 | SRM | spermidine synthase [Source:HGNC Symbol;Acc:HGNC:11296] | 1252 | 1.254 | 0.4357 | Yes |
| 18 | PUS1 | pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:15508] | 1337 | 1.186 | 0.4492 | Yes |
| 19 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 1401 | 1.148 | 0.4627 | Yes |
| 20 | PPRC1 | PPARG related coactivator 1 [Source:HGNC Symbol;Acc:HGNC:30025] | 1444 | 1.129 | 0.4766 | Yes |
| 21 | FARSA | phenylalanyl-tRNA synthetase subunit alpha [Source:HGNC Symbol;Acc:HGNC:3592] | 1462 | 1.121 | 0.4910 | Yes |
| 22 | MPHOSPH10 | M-phase phosphoprotein 10 [Source:HGNC Symbol;Acc:HGNC:7213] | 1516 | 1.100 | 0.5042 | Yes |
| 23 | NOP56 | NOP56 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:15911] | 1736 | 1.010 | 0.5117 | Yes |
| 24 | IMP4 | IMP U3 small nucleolar ribonucleoprotein 4 [Source:HGNC Symbol;Acc:HGNC:30856] | 1838 | 0.969 | 0.5218 | Yes |
| 25 | HSPE1 | heat shock protein family E (Hsp10) member 1 [Source:HGNC Symbol;Acc:HGNC:5269] | 1970 | 0.910 | 0.5304 | Yes |
| 26 | RCL1 | RNA terminal phosphate cyclase like 1 [Source:HGNC Symbol;Acc:HGNC:17687] | 2021 | 0.892 | 0.5409 | Yes |
| 27 | TCOF1 | treacle ribosome biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:11654] | 2196 | 0.820 | 0.5471 | Yes |
| 28 | HSPD1 | heat shock protein family D (Hsp60) member 1 [Source:HGNC Symbol;Acc:HGNC:5261] | 2348 | 0.770 | 0.5532 | Yes |
| 29 | PHB | prohibitin [Source:HGNC Symbol;Acc:HGNC:8912] | 2412 | 0.748 | 0.5614 | Yes |
| 30 | WDR74 | WD repeat domain 74 [Source:HGNC Symbol;Acc:HGNC:25529] | 2685 | 0.666 | 0.5629 | Yes |
| 31 | SLC19A1 | solute carrier family 19 member 1 [Source:HGNC Symbol;Acc:HGNC:10937] | 2874 | 0.620 | 0.5661 | Yes |
| 32 | PES1 | pescadillo ribosomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8848] | 3036 | 0.581 | 0.5694 | Yes |
| 33 | LAS1L | LAS1 like ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:25726] | 3162 | 0.553 | 0.5734 | Yes |
| 34 | GNL3 | G protein nucleolar 3 [Source:HGNC Symbol;Acc:HGNC:29931] | 3263 | 0.530 | 0.5778 | Yes |
| 35 | NOC4L | nucleolar complex associated 4 homolog [Source:HGNC Symbol;Acc:HGNC:28461] | 3328 | 0.516 | 0.5829 | Yes |
| 36 | AIMP2 | aminoacyl tRNA synthetase complex interacting multifunctional protein 2 [Source:HGNC Symbol;Acc:HGNC:20609] | 3666 | 0.448 | 0.5797 | No |
| 37 | NOLC1 | nucleolar and coiled-body phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15608] | 4474 | 0.314 | 0.5621 | No |
| 38 | NPM1 | nucleophosmin 1 [Source:HGNC Symbol;Acc:HGNC:7910] | 5153 | 0.209 | 0.5466 | No |
| 39 | TBRG4 | transforming growth factor beta regulator 4 [Source:HGNC Symbol;Acc:HGNC:17443] | 5172 | 0.205 | 0.5488 | No |
| 40 | TMEM97 | transmembrane protein 97 [Source:HGNC Symbol;Acc:HGNC:28106] | 6397 | 0.039 | 0.5163 | No |
| 41 | PRMT3 | protein arginine methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30163] | 6559 | 0.020 | 0.5122 | No |
| 42 | PPAN | peter pan homolog [Source:HGNC Symbol;Acc:HGNC:9227] | 28224 | -0.098 | -0.0715 | No |
| 43 | NDUFAF4 | NADH:ubiquinone oxidoreductase complex assembly factor 4 [Source:HGNC Symbol;Acc:HGNC:21034] | 30095 | -0.323 | -0.1177 | No |
| 44 | TFB2M | transcription factor B2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:18559] | 30499 | -0.378 | -0.1236 | No |
| 45 | RABEPK | Rab9 effector protein with kelch motifs [Source:HGNC Symbol;Acc:HGNC:16896] | 30510 | -0.380 | -0.1188 | No |
| 46 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 31026 | -0.458 | -0.1266 | No |
| 47 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 32153 | -0.642 | -0.1485 | No |
| 48 | SUPV3L1 | Suv3 like RNA helicase [Source:HGNC Symbol;Acc:HGNC:11471] | 32391 | -0.696 | -0.1457 | No |
| 49 | SLC29A2 | solute carrier family 29 member 2 [Source:HGNC Symbol;Acc:HGNC:11004] | 32827 | -0.800 | -0.1468 | No |
| 50 | CDK4 | cyclin dependent kinase 4 [Source:HGNC Symbol;Acc:HGNC:1773] | 34787 | -1.412 | -0.1809 | No |
| 51 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 34837 | -1.440 | -0.1631 | No |
| 52 | EXOSC5 | exosome component 5 [Source:HGNC Symbol;Acc:HGNC:24662] | 35126 | -1.583 | -0.1499 | No |
| 53 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35681 | -1.914 | -0.1394 | No |
| 54 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35722 | -1.939 | -0.1148 | No |
| 55 | MAP3K6 | mitogen-activated protein kinase kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6858] | 36168 | -2.302 | -0.0962 | No |
| 56 | CBX3 | chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553] | 36439 | -2.607 | -0.0689 | No |
| 57 | UNG | uracil DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:12572] | 36823 | -3.229 | -0.0364 | No |
| 58 | SORD | sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184] | 36842 | -3.281 | 0.0067 | No |
