Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | HALLMARK_PEROXISOME |
| Enrichment Score (ES) | -0.58311564 |
| Normalized Enrichment Score (NES) | -1.242411 |
| Nominal p-value | 0.07692308 |
| FDR q-value | 0.22389714 |
| FWER p-Value | 0.956 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit [Source:HGNC Symbol;Acc:HGNC:3433] | 119 | 3.448 | 0.0286 | No |
| 2 | ATXN1 | ataxin 1 [Source:HGNC Symbol;Acc:HGNC:10548] | 121 | 3.447 | 0.0605 | No |
| 3 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 241 | 2.828 | 0.0834 | No |
| 4 | ACSL4 | acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571] | 476 | 2.149 | 0.0969 | No |
| 5 | PRDX5 | peroxiredoxin 5 [Source:HGNC Symbol;Acc:HGNC:9355] | 829 | 1.590 | 0.1021 | No |
| 6 | SLC25A19 | solute carrier family 25 member 19 [Source:HGNC Symbol;Acc:HGNC:14409] | 992 | 1.438 | 0.1110 | No |
| 7 | CNBP | CCHC-type zinc finger nucleic acid binding protein [Source:HGNC Symbol;Acc:HGNC:13164] | 1232 | 1.262 | 0.1162 | No |
| 8 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 1415 | 1.142 | 0.1218 | No |
| 9 | TSPO | translocator protein [Source:HGNC Symbol;Acc:HGNC:1158] | 1586 | 1.075 | 0.1272 | No |
| 10 | CDK7 | cyclin dependent kinase 7 [Source:HGNC Symbol;Acc:HGNC:1778] | 1738 | 1.010 | 0.1324 | No |
| 11 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 2011 | 0.895 | 0.1333 | No |
| 12 | DHRS3 | dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693] | 2376 | 0.762 | 0.1305 | No |
| 13 | YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta [Source:HGNC Symbol;Acc:HGNC:12853] | 2935 | 0.605 | 0.1210 | No |
| 14 | CRABP2 | cellular retinoic acid binding protein 2 [Source:HGNC Symbol;Acc:HGNC:2339] | 3136 | 0.560 | 0.1208 | No |
| 15 | BCL10 | BCL10 immune signaling adaptor [Source:HGNC Symbol;Acc:HGNC:989] | 3363 | 0.508 | 0.1194 | No |
| 16 | ERCC3 | ERCC excision repair 3, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3435] | 3562 | 0.468 | 0.1184 | No |
| 17 | VPS4B | vacuolar protein sorting 4 homolog B [Source:HGNC Symbol;Acc:HGNC:10895] | 3735 | 0.434 | 0.1177 | No |
| 18 | ALB | albumin [Source:HGNC Symbol;Acc:HGNC:399] | 3850 | 0.415 | 0.1185 | No |
| 19 | CACNA1B | calcium voltage-gated channel subunit alpha1 B [Source:HGNC Symbol;Acc:HGNC:1389] | 4255 | 0.347 | 0.1108 | No |
| 20 | HRAS | HRas proto-oncogene, GTPase [Source:HGNC Symbol;Acc:HGNC:5173] | 4988 | 0.233 | 0.0931 | No |
| 21 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 5113 | 0.214 | 0.0918 | No |
| 22 | PEX14 | peroxisomal biogenesis factor 14 [Source:HGNC Symbol;Acc:HGNC:8856] | 5118 | 0.214 | 0.0936 | No |
| 23 | ACOX1 | acyl-CoA oxidase 1 [Source:HGNC Symbol;Acc:HGNC:119] | 5197 | 0.201 | 0.0934 | No |
| 24 | PEX11A | peroxisomal biogenesis factor 11 alpha [Source:HGNC Symbol;Acc:HGNC:8852] | 5214 | 0.199 | 0.0948 | No |
| 25 | PABPC1 | poly(A) binding protein cytoplasmic 1 [Source:HGNC Symbol;Acc:HGNC:8554] | 5757 | 0.121 | 0.0812 | No |
| 26 | NUDT19 | nudix hydrolase 19 [Source:HGNC Symbol;Acc:HGNC:32036] | 6064 | 0.081 | 0.0737 | No |
| 27 | IDI1 | isopentenyl-diphosphate delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:5387] | 6112 | 0.076 | 0.0732 | No |
| 28 | PEX5 | peroxisomal biogenesis factor 5 [Source:HGNC Symbol;Acc:HGNC:9719] | 6360 | 0.045 | 0.0669 | No |
| 29 | EPHX2 | epoxide hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3402] | 8285 | 0.000 | 0.0149 | No |
| 30 | EHHADH | enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3247] | 8300 | 0.000 | 0.0145 | No |
| 31 | GSTK1 | glutathione S-transferase kappa 1 [Source:HGNC Symbol;Acc:HGNC:16906] | 9966 | 0.000 | -0.0305 | No |
| 32 | SLC27A2 | solute carrier family 27 member 2 [Source:HGNC Symbol;Acc:HGNC:10996] | 11191 | 0.000 | -0.0636 | No |
| 33 | ESR2 | estrogen receptor 2 [Source:HGNC Symbol;Acc:HGNC:3468] | 12201 | 0.000 | -0.0909 | No |
| 34 | STS | steroid sulfatase [Source:HGNC Symbol;Acc:HGNC:11425] | 12674 | 0.000 | -0.1037 | No |
| 35 | TTR | transthyretin [Source:HGNC Symbol;Acc:HGNC:12405] | 12933 | 0.000 | -0.1106 | No |
| 36 | HSD11B2 | hydroxysteroid 11-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5209] | 14572 | 0.000 | -0.1549 | No |
| 37 | CEL | carboxyl ester lipase [Source:HGNC Symbol;Acc:HGNC:1848] | 15883 | 0.000 | -0.1903 | No |
| 38 | DIO1 | iodothyronine deiodinase 1 [Source:HGNC Symbol;Acc:HGNC:2883] | 15942 | 0.000 | -0.1919 | No |
| 39 | SERPINA6 | serpin family A member 6 [Source:HGNC Symbol;Acc:HGNC:1540] | 17816 | 0.000 | -0.2425 | No |
| 40 | SEMA3C | semaphorin 3C [Source:HGNC Symbol;Acc:HGNC:10725] | 17880 | 0.000 | -0.2442 | No |
| 41 | UGT2B17 | UDP glucuronosyltransferase family 2 member B17 [Source:HGNC Symbol;Acc:HGNC:12547] | 18202 | 0.000 | -0.2529 | No |
| 42 | SULT2B1 | sulfotransferase family 2B member 1 [Source:HGNC Symbol;Acc:HGNC:11459] | 23773 | 0.000 | -0.4035 | No |
| 43 | CRABP1 | cellular retinoic acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2338] | 24046 | 0.000 | -0.4109 | No |
| 44 | SCGB1A1 | secretoglobin family 1A member 1 [Source:HGNC Symbol;Acc:HGNC:12523] | 24233 | 0.000 | -0.4159 | No |
| 45 | HAO2 | hydroxyacid oxidase 2 [Source:HGNC Symbol;Acc:HGNC:4810] | 24895 | 0.000 | -0.4338 | No |
| 46 | FABP6 | fatty acid binding protein 6 [Source:HGNC Symbol;Acc:HGNC:3561] | 26859 | 0.000 | -0.4868 | No |
| 47 | ABCC8 | ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59] | 27462 | 0.000 | -0.5031 | No |
| 48 | PEX2 | peroxisomal biogenesis factor 2 [Source:HGNC Symbol;Acc:HGNC:9717] | 27657 | -0.028 | -0.5081 | No |
| 49 | PEX13 | peroxisomal biogenesis factor 13 [Source:HGNC Symbol;Acc:HGNC:8855] | 28788 | -0.161 | -0.5372 | No |
| 50 | NR1I2 | nuclear receptor subfamily 1 group I member 2 [Source:HGNC Symbol;Acc:HGNC:7968] | 28908 | -0.179 | -0.5387 | No |
| 51 | SOD1 | superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179] | 29098 | -0.201 | -0.5420 | No |
| 52 | ACOT8 | acyl-CoA thioesterase 8 [Source:HGNC Symbol;Acc:HGNC:15919] | 29187 | -0.211 | -0.5424 | No |
| 53 | ITGB1BP1 | integrin subunit beta 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23927] | 29575 | -0.263 | -0.5505 | No |
| 54 | CTBP1 | C-terminal binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2494] | 29659 | -0.273 | -0.5502 | No |
| 55 | FIS1 | fission, mitochondrial 1 [Source:HGNC Symbol;Acc:HGNC:21689] | 29744 | -0.282 | -0.5498 | No |
| 56 | ACSL1 | acyl-CoA synthetase long chain family member 1 [Source:HGNC Symbol;Acc:HGNC:3569] | 29772 | -0.285 | -0.5479 | No |
| 57 | ABCB9 | ATP binding cassette subfamily B member 9 [Source:HGNC Symbol;Acc:HGNC:50] | 30100 | -0.324 | -0.5538 | No |
| 58 | CLN8 | CLN8 transmembrane ER and ERGIC protein [Source:HGNC Symbol;Acc:HGNC:2079] | 30152 | -0.331 | -0.5521 | No |
| 59 | PEX6 | peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859] | 30816 | -0.425 | -0.5661 | No |
| 60 | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 [Source:HGNC Symbol;Acc:HGNC:11104] | 30883 | -0.434 | -0.5639 | No |
| 61 | ISOC1 | isochorismatase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24254] | 31027 | -0.458 | -0.5635 | No |
| 62 | RDH11 | retinol dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:17964] | 31032 | -0.458 | -0.5594 | No |
| 63 | SIAH1 | siah E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:10857] | 31382 | -0.510 | -0.5641 | No |
| 64 | CTPS1 | CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519] | 32014 | -0.617 | -0.5755 | No |
| 65 | ACSL5 | acyl-CoA synthetase long chain family member 5 [Source:HGNC Symbol;Acc:HGNC:16526] | 32053 | -0.625 | -0.5707 | No |
| 66 | HSD17B11 | hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960] | 32512 | -0.724 | -0.5764 | Yes |
| 67 | ABCB1 | ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] | 32690 | -0.765 | -0.5741 | Yes |
| 68 | GNPAT | glyceronephosphate O-acyltransferase [Source:HGNC Symbol;Acc:HGNC:4416] | 33016 | -0.845 | -0.5751 | Yes |
| 69 | SLC23A2 | solute carrier family 23 member 2 [Source:HGNC Symbol;Acc:HGNC:10973] | 33089 | -0.864 | -0.5691 | Yes |
| 70 | SLC25A17 | solute carrier family 25 member 17 [Source:HGNC Symbol;Acc:HGNC:10987] | 33254 | -0.909 | -0.5651 | Yes |
| 71 | ABCD3 | ATP binding cassette subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:67] | 33393 | -0.948 | -0.5601 | Yes |
| 72 | IDE | insulin degrading enzyme [Source:HGNC Symbol;Acc:HGNC:5381] | 33623 | -1.010 | -0.5569 | Yes |
| 73 | LONP2 | lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:HGNC:20598] | 34093 | -1.143 | -0.5591 | Yes |
| 74 | HMGCL | 3-hydroxy-3-methylglutaryl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:5005] | 34187 | -1.175 | -0.5507 | Yes |
| 75 | RXRG | retinoid X receptor gamma [Source:HGNC Symbol;Acc:HGNC:10479] | 34207 | -1.182 | -0.5403 | Yes |
| 76 | MLYCD | malonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150] | 34395 | -1.250 | -0.5338 | Yes |
| 77 | SLC25A4 | solute carrier family 25 member 4 [Source:HGNC Symbol;Acc:HGNC:10990] | 34421 | -1.257 | -0.5229 | Yes |
| 78 | FDPS | farnesyl diphosphate synthase [Source:HGNC Symbol;Acc:HGNC:3631] | 34580 | -1.326 | -0.5149 | Yes |
| 79 | DLG4 | discs large MAGUK scaffold protein 4 [Source:HGNC Symbol;Acc:HGNC:2903] | 35167 | -1.606 | -0.5159 | Yes |
| 80 | HSD17B4 | hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213] | 35205 | -1.627 | -0.5019 | Yes |
| 81 | SCP2 | sterol carrier protein 2 [Source:HGNC Symbol;Acc:HGNC:10606] | 35242 | -1.647 | -0.4876 | Yes |
| 82 | CAT | catalase [Source:HGNC Symbol;Acc:HGNC:1516] | 35287 | -1.669 | -0.4734 | Yes |
| 83 | RETSAT | retinol saturase [Source:HGNC Symbol;Acc:HGNC:25991] | 35330 | -1.689 | -0.4589 | Yes |
| 84 | CRAT | carnitine O-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2342] | 35473 | -1.778 | -0.4463 | Yes |
| 85 | PEX11B | peroxisomal biogenesis factor 11 beta [Source:HGNC Symbol;Acc:HGNC:8853] | 35613 | -1.860 | -0.4329 | Yes |
| 86 | ECI2 | enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601] | 35615 | -1.861 | -0.4157 | Yes |
| 87 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35626 | -1.864 | -0.3988 | Yes |
| 88 | ABCD1 | ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61] | 35837 | -2.026 | -0.3857 | Yes |
| 89 | CADM1 | cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5951] | 35879 | -2.062 | -0.3678 | Yes |
| 90 | IDH2 | isocitrate dehydrogenase (NADP(+)) 2 [Source:HGNC Symbol;Acc:HGNC:5383] | 35965 | -2.127 | -0.3504 | Yes |
| 91 | ALDH9A1 | aldehyde dehydrogenase 9 family member A1 [Source:HGNC Symbol;Acc:HGNC:412] | 35971 | -2.128 | -0.3309 | Yes |
| 92 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 36138 | -2.271 | -0.3144 | Yes |
| 93 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 36247 | -2.372 | -0.2954 | Yes |
| 94 | DHCR24 | 24-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2859] | 36334 | -2.463 | -0.2750 | Yes |
| 95 | ABCB4 | ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45] | 36344 | -2.475 | -0.2523 | Yes |
| 96 | ACAA1 | acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82] | 36407 | -2.554 | -0.2304 | Yes |
| 97 | ELOVL5 | ELOVL fatty acid elongase 5 [Source:HGNC Symbol;Acc:HGNC:21308] | 36424 | -2.579 | -0.2070 | Yes |
| 98 | ABCC5 | ATP binding cassette subfamily C member 5 [Source:HGNC Symbol;Acc:HGNC:56] | 36574 | -2.793 | -0.1853 | Yes |
| 99 | ECH1 | enoyl-CoA hydratase 1 [Source:HGNC Symbol;Acc:HGNC:3149] | 36596 | -2.823 | -0.1597 | Yes |
| 100 | HSD3B7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 [Source:HGNC Symbol;Acc:HGNC:18324] | 36746 | -3.084 | -0.1353 | Yes |
| 101 | CLN6 | CLN6 transmembrane ER protein [Source:HGNC Symbol;Acc:HGNC:2077] | 36868 | -3.343 | -0.1077 | Yes |
| 102 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36967 | -3.703 | -0.0761 | Yes |
| 103 | IDH1 | isocitrate dehydrogenase (NADP(+)) 1 [Source:HGNC Symbol;Acc:HGNC:5382] | 36979 | -3.774 | -0.0415 | Yes |
| 104 | ABCD2 | ATP binding cassette subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:66] | 37086 | -4.814 | 0.0001 | Yes |
