Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY |
| Enrichment Score (ES) | 0.46176496 |
| Normalized Enrichment Score (NES) | 1.0564415 |
| Nominal p-value | 0.30875576 |
| FDR q-value | 0.30994478 |
| FWER p-Value | 0.802 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 125 | 3.424 | 0.0606 | Yes |
| 2 | SBNO2 | strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158] | 171 | 3.167 | 0.1186 | Yes |
| 3 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 197 | 3.054 | 0.1749 | Yes |
| 4 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 241 | 2.828 | 0.2266 | Yes |
| 5 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 289 | 2.631 | 0.2745 | Yes |
| 6 | SRXN1 | sulfiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:16132] | 519 | 2.043 | 0.3065 | Yes |
| 7 | SELENOS | selenoprotein S [Source:HGNC Symbol;Acc:HGNC:30396] | 535 | 2.029 | 0.3440 | Yes |
| 8 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 577 | 1.967 | 0.3797 | Yes |
| 9 | ABCC1 | ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51] | 806 | 1.619 | 0.4038 | Yes |
| 10 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 1415 | 1.142 | 0.4087 | Yes |
| 11 | EGLN2 | egl-9 family hypoxia inducible factor 2 [Source:HGNC Symbol;Acc:HGNC:14660] | 1520 | 1.098 | 0.4264 | Yes |
| 12 | G6PD | glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057] | 1879 | 0.951 | 0.4345 | Yes |
| 13 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 2039 | 0.885 | 0.4467 | Yes |
| 14 | SCAF4 | SR-related CTD associated factor 4 [Source:HGNC Symbol;Acc:HGNC:19304] | 2396 | 0.754 | 0.4512 | Yes |
| 15 | LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 [Source:HGNC Symbol;Acc:HGNC:17955] | 2819 | 0.632 | 0.4516 | Yes |
| 16 | MSRA | methionine sulfoxide reductase A [Source:HGNC Symbol;Acc:HGNC:7377] | 2873 | 0.620 | 0.4618 | Yes |
| 17 | GSR | glutathione-disulfide reductase [Source:HGNC Symbol;Acc:HGNC:4623] | 3600 | 0.461 | 0.4508 | No |
| 18 | NQO1 | NAD(P)H quinone dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:2874] | 3857 | 0.414 | 0.4516 | No |
| 19 | MGST1 | microsomal glutathione S-transferase 1 [Source:HGNC Symbol;Acc:HGNC:7061] | 4118 | 0.370 | 0.4515 | No |
| 20 | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3434] | 4498 | 0.309 | 0.4470 | No |
| 21 | ATOX1 | antioxidant 1 copper chaperone [Source:HGNC Symbol;Acc:HGNC:798] | 6131 | 0.073 | 0.4044 | No |
| 22 | HHEX | hematopoietically expressed homeobox [Source:HGNC Symbol;Acc:HGNC:4901] | 6347 | 0.047 | 0.3994 | No |
| 23 | PRDX2 | peroxiredoxin 2 [Source:HGNC Symbol;Acc:HGNC:9353] | 6632 | 0.010 | 0.3919 | No |
| 24 | GPX3 | glutathione peroxidase 3 [Source:HGNC Symbol;Acc:HGNC:4555] | 9805 | 0.000 | 0.3063 | No |
| 25 | PDLIM1 | PDZ and LIM domain 1 [Source:HGNC Symbol;Acc:HGNC:2067] | 17780 | 0.000 | 0.0910 | No |
| 26 | IPCEF1 | interaction protein for cytohesin exchange factors 1 [Source:HGNC Symbol;Acc:HGNC:21204] | 17942 | 0.000 | 0.0867 | No |
| 27 | MPO | myeloperoxidase [Source:HGNC Symbol;Acc:HGNC:7218] | 19014 | 0.000 | 0.0578 | No |
| 28 | NDUFB4 | NADH:ubiquinone oxidoreductase subunit B4 [Source:HGNC Symbol;Acc:HGNC:7699] | 22907 | 0.000 | -0.0473 | No |
| 29 | STK25 | serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404] | 28598 | -0.139 | -0.1983 | No |
| 30 | SOD1 | superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179] | 29098 | -0.201 | -0.2080 | No |
| 31 | PRNP | prion protein [Source:HGNC Symbol;Acc:HGNC:9449] | 29563 | -0.261 | -0.2157 | No |
| 32 | FTL | ferritin light chain [Source:HGNC Symbol;Acc:HGNC:3999] | 29693 | -0.277 | -0.2140 | No |
| 33 | GLRX2 | glutaredoxin 2 [Source:HGNC Symbol;Acc:HGNC:16065] | 30937 | -0.442 | -0.2393 | No |
| 34 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 31617 | -0.551 | -0.2473 | No |
| 35 | GCLC | glutamate-cysteine ligase catalytic subunit [Source:HGNC Symbol;Acc:HGNC:4311] | 31927 | -0.598 | -0.2445 | No |
| 36 | FES | FES proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3657] | 32268 | -0.669 | -0.2412 | No |
| 37 | PTPA | protein phosphatase 2 phosphatase activator [Source:HGNC Symbol;Acc:HGNC:9308] | 32372 | -0.692 | -0.2310 | No |
| 38 | HMOX2 | heme oxygenase 2 [Source:HGNC Symbol;Acc:HGNC:5014] | 32546 | -0.733 | -0.2220 | No |
| 39 | TXNRD2 | thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155] | 32703 | -0.769 | -0.2118 | No |
| 40 | OXSR1 | oxidative stress responsive kinase 1 [Source:HGNC Symbol;Acc:HGNC:8508] | 32777 | -0.787 | -0.1991 | No |
| 41 | NDUFS2 | NADH:ubiquinone oxidoreductase core subunit S2 [Source:HGNC Symbol;Acc:HGNC:7708] | 33917 | -1.085 | -0.2096 | No |
| 42 | NDUFA6 | NADH:ubiquinone oxidoreductase subunit A6 [Source:HGNC Symbol;Acc:HGNC:7690] | 33936 | -1.092 | -0.1896 | No |
| 43 | PRDX6 | peroxiredoxin 6 [Source:HGNC Symbol;Acc:HGNC:16753] | 34017 | -1.120 | -0.1709 | No |
| 44 | CAT | catalase [Source:HGNC Symbol;Acc:HGNC:1516] | 35287 | -1.669 | -0.1739 | No |
| 45 | PFKP | phosphofructokinase, platelet [Source:HGNC Symbol;Acc:HGNC:8878] | 35790 | -1.990 | -0.1503 | No |
| 46 | LSP1 | lymphocyte specific protein 1 [Source:HGNC Symbol;Acc:HGNC:6707] | 35962 | -2.127 | -0.1152 | No |
| 47 | MBP | myelin basic protein [Source:HGNC Symbol;Acc:HGNC:6925] | 36333 | -2.463 | -0.0792 | No |
| 48 | CDKN2D | cyclin dependent kinase inhibitor 2D [Source:HGNC Symbol;Acc:HGNC:1790] | 36368 | -2.504 | -0.0333 | No |
| 49 | GPX4 | glutathione peroxidase 4 [Source:HGNC Symbol;Acc:HGNC:4556] | 36597 | -2.824 | 0.0133 | No |
