Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_GAQ_versus_WT_NA.greenbergcls.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | HALLMARK_SPERMATOGENESIS |
| Enrichment Score (ES) | -0.6197356 |
| Normalized Enrichment Score (NES) | -1.3580917 |
| Nominal p-value | 0.014925373 |
| FDR q-value | 0.10463499 |
| FWER p-Value | 0.454 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DPEP3 | dipeptidase 3 [Source:HGNC Symbol;Acc:HGNC:23029] | 273 | 2.684 | 0.0255 | No |
| 2 | IL13RA2 | interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975] | 883 | 1.542 | 0.0279 | No |
| 3 | PGS1 | phosphatidylglycerophosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:30029] | 1194 | 1.294 | 0.0354 | No |
| 4 | CNIH2 | cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744] | 1452 | 1.125 | 0.0423 | No |
| 5 | TLE4 | TLE family member 4, transcriptional corepressor [Source:HGNC Symbol;Acc:HGNC:11840] | 1563 | 1.082 | 0.0525 | No |
| 6 | CCT6B | chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621] | 1943 | 0.921 | 0.0536 | No |
| 7 | ELOVL3 | ELOVL fatty acid elongase 3 [Source:HGNC Symbol;Acc:HGNC:18047] | 2128 | 0.845 | 0.0590 | No |
| 8 | STAM2 | signal transducing adaptor molecule 2 [Source:HGNC Symbol;Acc:HGNC:11358] | 2436 | 0.741 | 0.0597 | No |
| 9 | PAPOLB | poly(A) polymerase beta [Source:HGNC Symbol;Acc:HGNC:15970] | 2555 | 0.707 | 0.0652 | No |
| 10 | CSNK2A2 | casein kinase 2 alpha 2 [Source:HGNC Symbol;Acc:HGNC:2459] | 3473 | 0.485 | 0.0463 | No |
| 11 | AGFG1 | ArfGAP with FG repeats 1 [Source:HGNC Symbol;Acc:HGNC:5175] | 3758 | 0.432 | 0.0440 | No |
| 12 | POMC | proopiomelanocortin [Source:HGNC Symbol;Acc:HGNC:9201] | 3809 | 0.422 | 0.0478 | No |
| 13 | RAD17 | RAD17 checkpoint clamp loader component [Source:HGNC Symbol;Acc:HGNC:9807] | 4149 | 0.365 | 0.0431 | No |
| 14 | CLVS1 | clavesin 1 [Source:HGNC Symbol;Acc:HGNC:23139] | 4325 | 0.335 | 0.0425 | No |
| 15 | PACRG | parkin coregulated [Source:HGNC Symbol;Acc:HGNC:19152] | 4783 | 0.266 | 0.0334 | No |
| 16 | TSN | translin [Source:HGNC Symbol;Acc:HGNC:12379] | 4832 | 0.258 | 0.0352 | No |
| 17 | NAA11 | N-alpha-acetyltransferase 11, NatA catalytic subunit [Source:HGNC Symbol;Acc:HGNC:28125] | 4835 | 0.257 | 0.0383 | No |
| 18 | TCP11 | t-complex 11 [Source:HGNC Symbol;Acc:HGNC:11658] | 5068 | 0.221 | 0.0347 | No |
| 19 | TEKT2 | tektin 2 [Source:HGNC Symbol;Acc:HGNC:11725] | 5103 | 0.216 | 0.0365 | No |
| 20 | PIAS2 | protein inhibitor of activated STAT 2 [Source:HGNC Symbol;Acc:HGNC:17311] | 5108 | 0.215 | 0.0390 | No |
| 21 | TUBA3C | tubulin alpha 3c [Source:HGNC Symbol;Acc:HGNC:12408] | 5298 | 0.186 | 0.0362 | No |
| 22 | ARL4A | ADP ribosylation factor like GTPase 4A [Source:HGNC Symbol;Acc:HGNC:695] | 5355 | 0.177 | 0.0368 | No |
| 23 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 5550 | 0.147 | 0.0334 | No |
| 24 | CLGN | calmegin [Source:HGNC Symbol;Acc:HGNC:2060] | 5570 | 0.144 | 0.0346 | No |
| 25 | ACTL7B | actin like 7B [Source:HGNC Symbol;Acc:HGNC:162] | 5996 | 0.088 | 0.0242 | No |
| 26 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 6135 | 0.073 | 0.0214 | No |
| 27 | PSMG1 | proteasome assembly chaperone 1 [Source:HGNC Symbol;Acc:HGNC:3043] | 6303 | 0.051 | 0.0175 | No |
| 28 | MAST2 | microtubule associated serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:19035] | 6652 | 0.007 | 0.0081 | No |
| 29 | SCG5 | secretogranin V [Source:HGNC Symbol;Acc:HGNC:10816] | 6919 | 0.000 | 0.0009 | No |
| 30 | SCG3 | secretogranin III [Source:HGNC Symbol;Acc:HGNC:13707] | 6921 | 0.000 | 0.0009 | No |
| 31 | ADCYAP1 | adenylate cyclase activating polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:241] | 7710 | 0.000 | -0.0204 | No |
| 32 | ART3 | ADP-ribosyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:725] | 7814 | 0.000 | -0.0232 | No |
| 33 | CCNA1 | cyclin A1 [Source:HGNC Symbol;Acc:HGNC:1577] | 7918 | 0.000 | -0.0260 | No |
| 34 | ZC2HC1C | zinc finger C2HC-type containing 1C [Source:HGNC Symbol;Acc:HGNC:20354] | 8599 | 0.000 | -0.0444 | No |
| 35 | HOXB1 | homeobox B1 [Source:HGNC Symbol;Acc:HGNC:5111] | 9141 | 0.000 | -0.0590 | No |
| 36 | ADAM2 | ADAM metallopeptidase domain 2 [Source:HGNC Symbol;Acc:HGNC:198] | 9217 | 0.000 | -0.0611 | No |
| 37 | ADAD1 | adenosine deaminase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30713] | 9368 | 0.000 | -0.0651 | No |
| 38 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 9387 | 0.000 | -0.0656 | No |
| 39 | CRISP2 | cysteine rich secretory protein 2 [Source:HGNC Symbol;Acc:HGNC:12024] | 9427 | 0.000 | -0.0667 | No |
| 40 | NPY5R | neuropeptide Y receptor Y5 [Source:HGNC Symbol;Acc:HGNC:7958] | 9434 | 0.000 | -0.0668 | No |
| 41 | DMRT1 | doublesex and mab-3 related transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:2934] | 9893 | 0.000 | -0.0792 | No |
| 42 | TULP2 | TUB like protein 2 [Source:HGNC Symbol;Acc:HGNC:12424] | 10438 | 0.000 | -0.0939 | No |
| 43 | CFTR | CF transmembrane conductance regulator [Source:HGNC Symbol;Acc:HGNC:1884] | 10469 | 0.000 | -0.0947 | No |
| 44 | LDHC | lactate dehydrogenase C [Source:HGNC Symbol;Acc:HGNC:6544] | 11385 | 0.000 | -0.1195 | No |
| 45 | PRM2 | protamine 2 [Source:HGNC Symbol;Acc:HGNC:9448] | 11826 | 0.000 | -0.1314 | No |
| 46 | SEPTIN4 | septin 4 [Source:HGNC Symbol;Acc:HGNC:9165] | 12004 | 0.000 | -0.1362 | No |
| 47 | JAM3 | junctional adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:15532] | 12343 | 0.000 | -0.1453 | No |
| 48 | THEG | theg spermatid protein [Source:HGNC Symbol;Acc:HGNC:13706] | 12954 | 0.000 | -0.1618 | No |
| 49 | TNP2 | transition protein 2 [Source:HGNC Symbol;Acc:HGNC:11952] | 15136 | 0.000 | -0.2209 | No |
| 50 | TNP1 | transition protein 1 [Source:HGNC Symbol;Acc:HGNC:11951] | 15138 | 0.000 | -0.2209 | No |
| 51 | HTR5A | 5-hydroxytryptamine receptor 5A [Source:HGNC Symbol;Acc:HGNC:5300] | 15746 | 0.000 | -0.2373 | No |
| 52 | MTNR1A | melatonin receptor 1A [Source:HGNC Symbol;Acc:HGNC:7463] | 15945 | 0.000 | -0.2427 | No |
| 53 | DCC | DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC:2701] | 16124 | 0.000 | -0.2475 | No |
| 54 | GAPDHS | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [Source:HGNC Symbol;Acc:HGNC:24864] | 16575 | 0.000 | -0.2597 | No |
| 55 | AKAP4 | A-kinase anchoring protein 4 [Source:HGNC Symbol;Acc:HGNC:374] | 16721 | 0.000 | -0.2636 | No |
| 56 | DMC1 | DNA meiotic recombinase 1 [Source:HGNC Symbol;Acc:HGNC:2927] | 16961 | 0.000 | -0.2701 | No |
| 57 | TKTL1 | transketolase like 1 [Source:HGNC Symbol;Acc:HGNC:11835] | 17274 | 0.000 | -0.2785 | No |
| 58 | HBZ | hemoglobin subunit zeta [Source:HGNC Symbol;Acc:HGNC:4835] | 17315 | 0.000 | -0.2796 | No |
| 59 | SYCP1 | synaptonemal complex protein 1 [Source:HGNC Symbol;Acc:HGNC:11487] | 17873 | 0.000 | -0.2947 | No |
| 60 | DNAJB8 | DnaJ heat shock protein family (Hsp40) member B8 [Source:HGNC Symbol;Acc:HGNC:23699] | 18518 | 0.000 | -0.3121 | No |
| 61 | IL12RB2 | interleukin 12 receptor subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:5972] | 19602 | 0.000 | -0.3414 | No |
| 62 | PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor [Source:HGNC Symbol;Acc:HGNC:17301] | 20723 | 0.000 | -0.3717 | No |
| 63 | SHE | Src homology 2 domain containing E [Source:HGNC Symbol;Acc:HGNC:27004] | 20838 | 0.000 | -0.3748 | No |
| 64 | H1-6 | H1.6 linker histone, cluster member [Source:HGNC Symbol;Acc:HGNC:4720] | 22773 | 0.000 | -0.4271 | No |
| 65 | MEP1B | meprin A subunit beta [Source:HGNC Symbol;Acc:HGNC:7020] | 23271 | 0.000 | -0.4406 | No |
| 66 | ACRV1 | acrosomal vesicle protein 1 [Source:HGNC Symbol;Acc:HGNC:127] | 23461 | 0.000 | -0.4457 | No |
| 67 | TSSK2 | testis specific serine kinase 2 [Source:HGNC Symbol;Acc:HGNC:11401] | 24569 | 0.000 | -0.4756 | No |
| 68 | SNAP91 | synaptosome associated protein 91 [Source:HGNC Symbol;Acc:HGNC:14986] | 24693 | 0.000 | -0.4790 | No |
| 69 | CST8 | cystatin 8 [Source:HGNC Symbol;Acc:HGNC:2480] | 24731 | 0.000 | -0.4800 | No |
| 70 | ODF1 | outer dense fiber of sperm tails 1 [Source:HGNC Symbol;Acc:HGNC:8113] | 26412 | 0.000 | -0.5254 | No |
| 71 | ZNRF4 | zinc and ring finger 4 [Source:HGNC Symbol;Acc:HGNC:17726] | 26450 | 0.000 | -0.5264 | No |
| 72 | ACE | angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] | 27095 | 0.000 | -0.5438 | No |
| 73 | MAP7 | microtubule associated protein 7 [Source:HGNC Symbol;Acc:HGNC:6869] | 27375 | 0.000 | -0.5514 | No |
| 74 | SLC2A5 | solute carrier family 2 member 5 [Source:HGNC Symbol;Acc:HGNC:11010] | 27451 | 0.000 | -0.5534 | No |
| 75 | OAZ3 | ornithine decarboxylase antizyme 3 [Source:HGNC Symbol;Acc:HGNC:8097] | 27843 | -0.051 | -0.5634 | No |
| 76 | NEFH | neurofilament heavy [Source:HGNC Symbol;Acc:HGNC:7737] | 27845 | -0.051 | -0.5628 | No |
| 77 | PHKG2 | phosphorylase kinase catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:8931] | 27921 | -0.062 | -0.5640 | No |
| 78 | GPR182 | G protein-coupled receptor 182 [Source:HGNC Symbol;Acc:HGNC:13708] | 28018 | -0.069 | -0.5658 | No |
| 79 | YBX2 | Y-box binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17948] | 28025 | -0.070 | -0.5651 | No |
| 80 | COIL | coilin [Source:HGNC Symbol;Acc:HGNC:2184] | 28052 | -0.073 | -0.5649 | No |
| 81 | ACRBP | acrosin binding protein [Source:HGNC Symbol;Acc:HGNC:17195] | 28210 | -0.096 | -0.5680 | No |
| 82 | GAD1 | glutamate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:4092] | 28217 | -0.097 | -0.5670 | No |
| 83 | GSTM3 | glutathione S-transferase mu 3 [Source:HGNC Symbol;Acc:HGNC:4635] | 28301 | -0.108 | -0.5679 | No |
| 84 | TALDO1 | transaldolase 1 [Source:HGNC Symbol;Acc:HGNC:11559] | 28337 | -0.112 | -0.5675 | No |
| 85 | PEBP1 | phosphatidylethanolamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8630] | 28754 | -0.156 | -0.5768 | No |
| 86 | MLLT10 | MLLT10 histone lysine methyltransferase DOT1L cofactor [Source:HGNC Symbol;Acc:HGNC:16063] | 28820 | -0.165 | -0.5765 | No |
| 87 | IP6K1 | inositol hexakisphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:18360] | 28931 | -0.182 | -0.5773 | No |
| 88 | DDX25 | DEAD-box helicase 25 [Source:HGNC Symbol;Acc:HGNC:18698] | 28975 | -0.188 | -0.5761 | No |
| 89 | MLF1 | myeloid leukemia factor 1 [Source:HGNC Symbol;Acc:HGNC:7125] | 29172 | -0.209 | -0.5789 | No |
| 90 | ALOX15 | arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433] | 29204 | -0.214 | -0.5771 | No |
| 91 | DDX4 | DEAD-box helicase 4 [Source:HGNC Symbol;Acc:HGNC:18700] | 30337 | -0.355 | -0.6034 | No |
| 92 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 30682 | -0.404 | -0.6077 | No |
| 93 | PDHA2 | pyruvate dehydrogenase E1 subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8807] | 30717 | -0.409 | -0.6036 | No |
| 94 | CLPB | caseinolytic mitochondrial matrix peptidase chaperone subunit B [Source:HGNC Symbol;Acc:HGNC:30664] | 31104 | -0.468 | -0.6083 | No |
| 95 | HSPA1L | heat shock protein family A (Hsp70) member 1 like [Source:HGNC Symbol;Acc:HGNC:5234] | 31526 | -0.536 | -0.6132 | Yes |
| 96 | ZPBP | zona pellucida binding protein [Source:HGNC Symbol;Acc:HGNC:15662] | 31610 | -0.551 | -0.6087 | Yes |
| 97 | BRAF | B-Raf proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1097] | 31623 | -0.552 | -0.6022 | Yes |
| 98 | MTOR | mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942] | 31699 | -0.564 | -0.5973 | Yes |
| 99 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31738 | -0.568 | -0.5914 | Yes |
| 100 | VDAC3 | voltage dependent anion channel 3 [Source:HGNC Symbol;Acc:HGNC:12674] | 31891 | -0.591 | -0.5883 | Yes |
| 101 | SIRT1 | sirtuin 1 [Source:HGNC Symbol;Acc:HGNC:14929] | 32222 | -0.658 | -0.5891 | Yes |
| 102 | CHFR | checkpoint with forkhead and ring finger domains [Source:HGNC Symbol;Acc:HGNC:20455] | 32258 | -0.666 | -0.5819 | Yes |
| 103 | RPL39L | ribosomal protein L39 like [Source:HGNC Symbol;Acc:HGNC:17094] | 32556 | -0.734 | -0.5809 | Yes |
| 104 | PRKAR2A | protein kinase cAMP-dependent type II regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9391] | 33166 | -0.885 | -0.5866 | Yes |
| 105 | PHF7 | PHD finger protein 7 [Source:HGNC Symbol;Acc:HGNC:18458] | 33235 | -0.903 | -0.5773 | Yes |
| 106 | GFI1 | growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237] | 33288 | -0.920 | -0.5675 | Yes |
| 107 | PARP2 | poly(ADP-ribose) polymerase 2 [Source:HGNC Symbol;Acc:HGNC:272] | 33450 | -0.960 | -0.5601 | Yes |
| 108 | IDE | insulin degrading enzyme [Source:HGNC Symbol;Acc:HGNC:5381] | 33623 | -1.010 | -0.5523 | Yes |
| 109 | SPATA6 | spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309] | 33727 | -1.039 | -0.5424 | Yes |
| 110 | PGK2 | phosphoglycerate kinase 2 [Source:HGNC Symbol;Acc:HGNC:8898] | 33806 | -1.055 | -0.5316 | Yes |
| 111 | NOS1 | nitric oxide synthase 1 [Source:HGNC Symbol;Acc:HGNC:7872] | 33989 | -1.113 | -0.5228 | Yes |
| 112 | SLC12A2 | solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911] | 34055 | -1.132 | -0.5107 | Yes |
| 113 | ZC3H14 | zinc finger CCCH-type containing 14 [Source:HGNC Symbol;Acc:HGNC:20509] | 34170 | -1.167 | -0.4995 | Yes |
| 114 | NF2 | neurofibromin 2 [Source:HGNC Symbol;Acc:HGNC:7773] | 35116 | -1.578 | -0.5057 | Yes |
| 115 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 35128 | -1.584 | -0.4866 | Yes |
| 116 | GSG1 | germ cell associated 1 [Source:HGNC Symbol;Acc:HGNC:19716] | 35210 | -1.633 | -0.4688 | Yes |
| 117 | HSPA2 | heat shock protein family A (Hsp70) member 2 [Source:HGNC Symbol;Acc:HGNC:5235] | 35350 | -1.702 | -0.4517 | Yes |
| 118 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 35561 | -1.824 | -0.4350 | Yes |
| 119 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35605 | -1.855 | -0.4134 | Yes |
| 120 | GMCL1 | germ cell-less 1, spermatogenesis associated [Source:HGNC Symbol;Acc:HGNC:23843] | 35608 | -1.857 | -0.3907 | Yes |
| 121 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35653 | -1.889 | -0.3687 | Yes |
| 122 | NPHP1 | nephrocystin 1 [Source:HGNC Symbol;Acc:HGNC:7905] | 35762 | -1.973 | -0.3475 | Yes |
| 123 | IFT88 | intraflagellar transport 88 [Source:HGNC Symbol;Acc:HGNC:20606] | 35765 | -1.974 | -0.3233 | Yes |
| 124 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35787 | -1.989 | -0.2995 | Yes |
| 125 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35922 | -2.100 | -0.2774 | Yes |
| 126 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36013 | -2.163 | -0.2533 | Yes |
| 127 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36101 | -2.242 | -0.2281 | Yes |
| 128 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36160 | -2.294 | -0.2016 | Yes |
| 129 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36164 | -2.301 | -0.1735 | Yes |
| 130 | TOPBP1 | DNA topoisomerase II binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17008] | 36291 | -2.418 | -0.1472 | Yes |
| 131 | PCSK4 | proprotein convertase subtilisin/kexin type 4 [Source:HGNC Symbol;Acc:HGNC:8746] | 36306 | -2.431 | -0.1178 | Yes |
| 132 | HSPA4L | heat shock protein family A (Hsp70) member 4 like [Source:HGNC Symbol;Acc:HGNC:17041] | 36392 | -2.539 | -0.0890 | Yes |
| 133 | STRBP | spermatid perinuclear RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16462] | 36395 | -2.541 | -0.0579 | Yes |
| 134 | TNNI3 | troponin I3, cardiac type [Source:HGNC Symbol;Acc:HGNC:11947] | 36431 | -2.591 | -0.0271 | Yes |
| 135 | LPIN1 | lipin 1 [Source:HGNC Symbol;Acc:HGNC:13345] | 36952 | -3.659 | 0.0037 | Yes |
