Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | CHR17Q12 |
| Enrichment Score (ES) | 0.5277272 |
| Normalized Enrichment Score (NES) | 1.4154382 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.25515902 |
| FWER p-Value | 0.488 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 0 | 4.989 | 0.0547 | Yes |
| 2 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 37 | 4.718 | 0.1055 | Yes |
| 3 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 60 | 4.454 | 0.1537 | Yes |
| 4 | SLFN5 | schlafen family member 5 [Source:HGNC Symbol;Acc:HGNC:28286] | 61 | 4.443 | 0.2025 | Yes |
| 5 | SLFN13 | schlafen family member 13 [Source:HGNC Symbol;Acc:HGNC:26481] | 121 | 3.965 | 0.2444 | Yes |
| 6 | SLFN11 | schlafen family member 11 [Source:HGNC Symbol;Acc:HGNC:26633] | 152 | 3.780 | 0.2850 | Yes |
| 7 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 274 | 3.106 | 0.3158 | Yes |
| 8 | RFFL | ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:24821] | 471 | 2.417 | 0.3370 | Yes |
| 9 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 644 | 2.075 | 0.3551 | Yes |
| 10 | STARD3 | StAR related lipid transfer domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17579] | 675 | 2.025 | 0.3765 | Yes |
| 11 | UNC45B | unc-45 myosin chaperone B [Source:HGNC Symbol;Acc:HGNC:14304] | 839 | 1.740 | 0.3912 | Yes |
| 12 | LASP1 | LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513] | 1028 | 1.520 | 0.4027 | Yes |
| 13 | CWC25 | CWC25 spliceosome associated protein homolog [Source:HGNC Symbol;Acc:HGNC:25989] | 1143 | 1.439 | 0.4154 | Yes |
| 14 | DHRS11 | dehydrogenase/reductase 11 [Source:HGNC Symbol;Acc:HGNC:28639] | 1263 | 1.339 | 0.4269 | Yes |
| 15 | TCAP | titin-cap [Source:HGNC Symbol;Acc:HGNC:11610] | 1281 | 1.328 | 0.4410 | Yes |
| 16 | CDK12 | cyclin dependent kinase 12 [Source:HGNC Symbol;Acc:HGNC:24224] | 1557 | 1.145 | 0.4461 | Yes |
| 17 | NLE1 | notchless homolog 1 [Source:HGNC Symbol;Acc:HGNC:19889] | 1569 | 1.139 | 0.4583 | Yes |
| 18 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 1595 | 1.124 | 0.4700 | Yes |
| 19 | AP2B1 | adaptor related protein complex 2 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:563] | 1827 | 0.998 | 0.4747 | Yes |
| 20 | MIEN1 | migration and invasion enhancer 1 [Source:HGNC Symbol;Acc:HGNC:28230] | 1993 | 0.922 | 0.4803 | Yes |
| 21 | ZNHIT3 | zinc finger HIT-type containing 3 [Source:HGNC Symbol;Acc:HGNC:12309] | 2245 | 0.819 | 0.4825 | Yes |
| 22 | HEATR9 | HEAT repeat containing 9 [Source:HGNC Symbol;Acc:HGNC:26548] | 2366 | 0.776 | 0.4878 | Yes |
| 23 | ZNF830 | zinc finger protein 830 [Source:HGNC Symbol;Acc:HGNC:28291] | 2404 | 0.764 | 0.4952 | Yes |
| 24 | PGAP3 | post-GPI attachment to proteins phospholipase 3 [Source:HGNC Symbol;Acc:HGNC:23719] | 2492 | 0.736 | 0.5009 | Yes |
| 25 | MYO19 | myosin XIX [Source:HGNC Symbol;Acc:HGNC:26234] | 2503 | 0.733 | 0.5087 | Yes |
| 26 | SRCIN1 | SRC kinase signaling inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:29506] | 2682 | 0.674 | 0.5112 | Yes |
| 27 | CCT6B | chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621] | 2763 | 0.647 | 0.5162 | Yes |
| 28 | SOCS7 | suppressor of cytokine signaling 7 [Source:HGNC Symbol;Acc:HGNC:29846] | 2928 | 0.596 | 0.5183 | Yes |
| 29 | PEX12 | peroxisomal biogenesis factor 12 [Source:HGNC Symbol;Acc:HGNC:8854] | 3080 | 0.562 | 0.5204 | Yes |
| 30 | PSMB3 | proteasome 20S subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:9540] | 3100 | 0.557 | 0.5259 | Yes |
| 31 | MED1 | mediator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:9234] | 3246 | 0.520 | 0.5277 | Yes |
| 32 | E2F3P1 | E2F transcription factor 3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:3116] | 3691 | 0.422 | 0.5203 | No |
| 33 | LIG3 | DNA ligase 3 [Source:HGNC Symbol;Acc:HGNC:6600] | 3802 | 0.401 | 0.5218 | No |
| 34 | FBXO47 | F-box protein 47 [Source:HGNC Symbol;Acc:HGNC:31969] | 4024 | 0.355 | 0.5197 | No |
| 35 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 4987 | 0.192 | 0.4958 | No |
| 36 | ARL5C | ADP ribosylation factor like GTPase 5C [Source:HGNC Symbol;Acc:HGNC:31111] | 5424 | 0.130 | 0.4854 | No |
| 37 | GGNBP2 | gametogenetin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19357] | 5621 | 0.107 | 0.4813 | No |
| 38 | PIGW | phosphatidylinositol glycan anchor biosynthesis class W [Source:HGNC Symbol;Acc:HGNC:23213] | 5641 | 0.104 | 0.4819 | No |
| 39 | AATF | apoptosis antagonizing transcription factor [Source:HGNC Symbol;Acc:HGNC:19235] | 5715 | 0.094 | 0.4809 | No |
| 40 | YWHAEP7 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:49437] | 5717 | 0.094 | 0.4819 | No |
| 41 | HNF1B | HNF1 homeobox B [Source:HGNC Symbol;Acc:HGNC:11630] | 5793 | 0.084 | 0.4808 | No |
| 42 | RPL19 | ribosomal protein L19 [Source:HGNC Symbol;Acc:HGNC:10312] | 6306 | 0.009 | 0.4671 | No |
| 43 | TAF15 | TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547] | 6314 | 0.008 | 0.4670 | No |
| 44 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 6399 | 0.000 | 0.4647 | No |
| 45 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 6400 | 0.000 | 0.4647 | No |
| 46 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6401 | 0.000 | 0.4647 | No |
| 47 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6421 | 0.000 | 0.4642 | No |
| 48 | CCL16 | C-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:10614] | 6424 | 0.000 | 0.4641 | No |
| 49 | CCL15 | C-C motif chemokine ligand 15 [Source:HGNC Symbol;Acc:HGNC:10613] | 6426 | 0.000 | 0.4641 | No |
| 50 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6430 | 0.000 | 0.4640 | No |
| 51 | TBC1D3 | TBC1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:19031] | 7563 | 0.000 | 0.4334 | No |
| 52 | LYZL6 | lysozyme like 6 [Source:HGNC Symbol;Acc:HGNC:29614] | 7870 | 0.000 | 0.4251 | No |
| 53 | ASIC2 | acid sensing ion channel subunit 2 [Source:HGNC Symbol;Acc:HGNC:99] | 7922 | 0.000 | 0.4237 | No |
| 54 | MIR2909 | microRNA 2909 [Source:HGNC Symbol;Acc:HGNC:38372] | 9077 | 0.000 | 0.3925 | No |
| 55 | RASL10B | RAS like family 10 member B [Source:HGNC Symbol;Acc:HGNC:30295] | 9801 | 0.000 | 0.3729 | No |
| 56 | GRB7 | growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567] | 9866 | 0.000 | 0.3712 | No |
| 57 | AA06 | uncharacterized LOC100506677 [Source:NCBI gene (formerly Entrezgene);Acc:100506677] | 10163 | 0.000 | 0.3632 | No |
| 58 | PNMT | phenylethanolamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:9160] | 10542 | 0.000 | 0.3530 | No |
| 59 | C17orf50 | chromosome 17 open reading frame 50 [Source:HGNC Symbol;Acc:HGNC:29581] | 11675 | 0.000 | 0.3223 | No |
| 60 | C17orf78 | chromosome 17 open reading frame 78 [Source:HGNC Symbol;Acc:HGNC:26831] | 11701 | 0.000 | 0.3217 | No |
| 61 | C17orf98 | chromosome 17 open reading frame 98 [Source:HGNC Symbol;Acc:HGNC:34492] | 11723 | 0.000 | 0.3211 | No |
| 62 | ERBB2 | erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430] | 11956 | 0.000 | 0.3148 | No |
| 63 | SNHG30 | small nucleolar RNA host gene 30 [Source:HGNC Symbol;Acc:HGNC:52836] | 12154 | 0.000 | 0.3095 | No |
| 64 | SLFN14 | schlafen family member 14 [Source:HGNC Symbol;Acc:HGNC:32689] | 12209 | 0.000 | 0.3080 | No |
| 65 | RNU6-1192P | RNA, U6 small nuclear 1192, pseudogene [Source:HGNC Symbol;Acc:HGNC:48155] | 12857 | 0.000 | 0.2905 | No |
| 66 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14670 | 0.000 | 0.2415 | No |
| 67 | SLC35G3 | solute carrier family 35 member G3 [Source:HGNC Symbol;Acc:HGNC:26848] | 15907 | 0.000 | 0.2081 | No |
| 68 | RN7SL301P | RNA, 7SL, cytoplasmic 301, pseudogene [Source:HGNC Symbol;Acc:HGNC:46317] | 15978 | 0.000 | 0.2062 | No |
| 69 | SNORA21 | small nucleolar RNA, H/ACA box 21 [Source:HGNC Symbol;Acc:HGNC:32611] | 16053 | 0.000 | 0.2042 | No |
| 70 | C17orf102 | chromosome 17 open reading frame 102 [Source:HGNC Symbol;Acc:HGNC:34412] | 16521 | 0.000 | 0.1915 | No |
| 71 | RNU6-866P | RNA, U6 small nuclear 866, pseudogene [Source:HGNC Symbol;Acc:HGNC:47829] | 16990 | 0.000 | 0.1789 | No |
| 72 | RNA5SP440 | RNA, 5S ribosomal pseudogene 440 [Source:HGNC Symbol;Acc:HGNC:43340] | 17202 | 0.000 | 0.1732 | No |
| 73 | RNA5SP439 | RNA, 5S ribosomal pseudogene 439 [Source:HGNC Symbol;Acc:HGNC:43339] | 17236 | 0.000 | 0.1723 | No |
| 74 | RNA5SP438 | RNA, 5S ribosomal pseudogene 438 [Source:HGNC Symbol;Acc:HGNC:43338] | 17237 | 0.000 | 0.1723 | No |
| 75 | CCL15-CCL14 | CCL15-CCL14 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44436] | 17349 | 0.000 | 0.1693 | No |
| 76 | SNORD7 | small nucleolar RNA, C/D box 7 [Source:HGNC Symbol;Acc:HGNC:32704] | 17386 | 0.000 | 0.1683 | No |
| 77 | PPP1R1B | protein phosphatase 1 regulatory inhibitor subunit 1B [Source:HGNC Symbol;Acc:HGNC:9287] | 17547 | 0.000 | 0.1640 | No |
| 78 | LRRC37A9P | leucine rich repeat containing 37 member A9, pseudogene [Source:HGNC Symbol;Acc:HGNC:43813] | 17592 | 0.000 | 0.1628 | No |
| 79 | RNU6-489P | RNA, U6 small nuclear 489, pseudogene [Source:HGNC Symbol;Acc:HGNC:47452] | 18369 | 0.000 | 0.1418 | No |
| 80 | RNU6-233P | RNA, U6 small nuclear 233, pseudogene [Source:HGNC Symbol;Acc:HGNC:47196] | 18771 | 0.000 | 0.1309 | No |
| 81 | NEUROD2 | neuronal differentiation 2 [Source:HGNC Symbol;Acc:HGNC:7763] | 19120 | 0.000 | 0.1215 | No |
| 82 | LINC01989 | long intergenic non-protein coding RNA 1989 [Source:HGNC Symbol;Acc:HGNC:52821] | 20235 | 0.000 | 0.0914 | No |
| 83 | LINC02079 | long intergenic non-protein coding RNA 2079 [Source:HGNC Symbol;Acc:HGNC:52927] | 21433 | 0.000 | 0.0590 | No |
| 84 | TBC1D3K | TBC1 domain family member 3K [Source:HGNC Symbol;Acc:HGNC:51245] | 22052 | 0.000 | 0.0423 | No |
| 85 | TBC1D3L | TBC1 domain family member 3L [Source:HGNC Symbol;Acc:HGNC:51246] | 22053 | 0.000 | 0.0423 | No |
| 86 | TBC1D3B | TBC1 domain family member 3B [Source:HGNC Symbol;Acc:HGNC:27011] | 22058 | 0.000 | 0.0421 | No |
| 87 | TBC1D3E | TBC1 domain family member 3E [Source:HGNC Symbol;Acc:HGNC:27071] | 22060 | 0.000 | 0.0421 | No |
| 88 | TBC1D3F | TBC1 domain family member 3F [Source:HGNC Symbol;Acc:HGNC:18257] | 22061 | 0.000 | 0.0421 | No |
| 89 | TBC1D3C | TBC1 domain family member 3C [Source:HGNC Symbol;Acc:HGNC:24889] | 22063 | 0.000 | 0.0421 | No |
| 90 | TBC1D3D | TBC1 domain family member 3D [Source:HGNC Symbol;Acc:HGNC:28944] | 22064 | 0.000 | 0.0421 | No |
| 91 | TBC1D3I | TBC1 domain family member 3I [Source:HGNC Symbol;Acc:HGNC:32709] | 22065 | 0.000 | 0.0421 | No |
| 92 | TBC1D3J | TBC1 domain family member 3J [Source:HGNC Symbol;Acc:HGNC:51247] | 22067 | 0.000 | 0.0421 | No |
| 93 | TBC1D3G | TBC1 domain family member 3G [Source:HGNC Symbol;Acc:HGNC:29860] | 22069 | 0.000 | 0.0420 | No |
| 94 | TBC1D3H | TBC1 domain family member 3H [Source:HGNC Symbol;Acc:HGNC:30708] | 22070 | 0.000 | 0.0420 | No |
| 95 | TMEM132E | transmembrane protein 132E [Source:HGNC Symbol;Acc:HGNC:26991] | 22292 | 0.000 | 0.0361 | No |
| 96 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22675 | 0.000 | 0.0257 | No |
| 97 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22677 | 0.000 | 0.0257 | No |
| 98 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22684 | 0.000 | 0.0255 | No |
| 99 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 22685 | 0.000 | 0.0255 | No |
| 100 | FNDC8 | fibronectin type III domain containing 8 [Source:HGNC Symbol;Acc:HGNC:25286] | 25498 | 0.000 | -0.0506 | No |
| 101 | RNU6-840P | RNA, U6 small nuclear 840, pseudogene [Source:HGNC Symbol;Acc:HGNC:47803] | 25603 | 0.000 | -0.0534 | No |
| 102 | GAS2L2 | growth arrest specific 2 like 2 [Source:HGNC Symbol;Acc:HGNC:24846] | 26422 | 0.000 | -0.0755 | No |
| 103 | MIR4734 | microRNA 4734 [Source:HGNC Symbol;Acc:HGNC:41572] | 26835 | 0.000 | -0.0866 | No |
| 104 | MIR4726 | microRNA 4726 [Source:HGNC Symbol;Acc:HGNC:41722] | 26852 | 0.000 | -0.0871 | No |
| 105 | MIR4728 | microRNA 4728 [Source:HGNC Symbol;Acc:HGNC:41632] | 26855 | 0.000 | -0.0871 | No |
| 106 | MIR4727 | microRNA 4727 [Source:HGNC Symbol;Acc:HGNC:41709] | 26856 | 0.000 | -0.0871 | No |
| 107 | LRRC37A11P | leucine rich repeat containing 37 member A11, pseudogene [Source:HGNC Symbol;Acc:HGNC:43815] | 27102 | 0.000 | -0.0938 | No |
| 108 | LHX1 | LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6593] | 27461 | -0.056 | -0.1028 | No |
| 109 | EPOP | elongin BC and polycomb repressive complex 2 associated protein [Source:HGNC Symbol;Acc:HGNC:34493] | 27689 | -0.080 | -0.1081 | No |
| 110 | RPL23 | ribosomal protein L23 [Source:HGNC Symbol;Acc:HGNC:10316] | 28044 | -0.127 | -0.1163 | No |
| 111 | ARHGAP23 | Rho GTPase activating protein 23 [Source:HGNC Symbol;Acc:HGNC:29293] | 28446 | -0.178 | -0.1252 | No |
| 112 | TOMM20P2 | TOMM20 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:50519] | 30639 | -0.497 | -0.1790 | No |
| 113 | LINC00672 | long intergenic non-protein coding RNA 672 [Source:HGNC Symbol;Acc:HGNC:44353] | 30967 | -0.551 | -0.1818 | No |
| 114 | MLLT6 | MLLT6, PHD finger containing [Source:HGNC Symbol;Acc:HGNC:7138] | 31293 | -0.606 | -0.1840 | No |
| 115 | CISD3 | CDGSH iron sulfur domain 3 [Source:HGNC Symbol;Acc:HGNC:27578] | 31443 | -0.637 | -0.1810 | No |
| 116 | SYNRG | synergin gamma [Source:HGNC Symbol;Acc:HGNC:557] | 31784 | -0.712 | -0.1824 | No |
| 117 | MRM1 | mitochondrial rRNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26202] | 31921 | -0.743 | -0.1780 | No |
| 118 | PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase type 2 beta [Source:HGNC Symbol;Acc:HGNC:8998] | 32886 | -0.984 | -0.1933 | No |
| 119 | MMP28 | matrix metallopeptidase 28 [Source:HGNC Symbol;Acc:HGNC:14366] | 32940 | -0.999 | -0.1837 | No |
| 120 | HMGB1P24 | high mobility group box 1 pseudogene 24 [Source:HGNC Symbol;Acc:HGNC:39115] | 34085 | -1.367 | -0.1997 | No |
| 121 | GPR179 | G protein-coupled receptor 179 [Source:HGNC Symbol;Acc:HGNC:31371] | 34293 | -1.453 | -0.1894 | No |
| 122 | CACNB1 | calcium voltage-gated channel auxiliary subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:1401] | 34297 | -1.454 | -0.1735 | No |
| 123 | RAD51D | RAD51 paralog D [Source:HGNC Symbol;Acc:HGNC:9823] | 34425 | -1.512 | -0.1603 | No |
| 124 | MRPL45 | mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651] | 34527 | -1.551 | -0.1461 | No |
| 125 | ACACA | acetyl-CoA carboxylase alpha [Source:HGNC Symbol;Acc:HGNC:84] | 34549 | -1.561 | -0.1295 | No |
| 126 | RDM1 | RAD52 motif containing 1 [Source:HGNC Symbol;Acc:HGNC:19950] | 35042 | -1.792 | -0.1232 | No |
| 127 | DDX52 | DExD-box helicase 52 [Source:HGNC Symbol;Acc:HGNC:20038] | 35169 | -1.861 | -0.1062 | No |
| 128 | PLXDC1 | plexin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20945] | 35457 | -2.055 | -0.0914 | No |
| 129 | TADA2A | transcriptional adaptor 2A [Source:HGNC Symbol;Acc:HGNC:11531] | 35536 | -2.107 | -0.0704 | No |
| 130 | PCGF2 | polycomb group ring finger 2 [Source:HGNC Symbol;Acc:HGNC:12929] | 36323 | -2.849 | -0.0604 | No |
| 131 | FBXL20 | F-box and leucine rich repeat protein 20 [Source:HGNC Symbol;Acc:HGNC:24679] | 36625 | -3.198 | -0.0335 | No |
| 132 | STAC2 | SH3 and cysteine rich domain 2 [Source:HGNC Symbol;Acc:HGNC:23990] | 37012 | -4.197 | 0.0021 | No |
