Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | BROWNE_INTERFERON_RESPONSIVE_GENES |
| Enrichment Score (ES) | 0.8548365 |
| Normalized Enrichment Score (NES) | 2.0680923 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 6 | 4.960 | 0.0352 | Yes |
| 2 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 23 | 4.827 | 0.0691 | Yes |
| 3 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 31 | 4.755 | 0.1028 | Yes |
| 4 | OASL | 2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] | 33 | 4.742 | 0.1365 | Yes |
| 5 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 35 | 4.721 | 0.1701 | Yes |
| 6 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 48 | 4.592 | 0.2025 | Yes |
| 7 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 55 | 4.511 | 0.2344 | Yes |
| 8 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 56 | 4.507 | 0.2665 | Yes |
| 9 | ISG20 | interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] | 65 | 4.413 | 0.2977 | Yes |
| 10 | TLR3 | toll like receptor 3 [Source:HGNC Symbol;Acc:HGNC:11849] | 76 | 4.252 | 0.3277 | Yes |
| 11 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 82 | 4.215 | 0.3576 | Yes |
| 12 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 85 | 4.196 | 0.3874 | Yes |
| 13 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 92 | 4.151 | 0.4168 | Yes |
| 14 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 112 | 4.003 | 0.4448 | Yes |
| 15 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 128 | 3.919 | 0.4723 | Yes |
| 16 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 134 | 3.887 | 0.4998 | Yes |
| 17 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 160 | 3.711 | 0.5256 | Yes |
| 18 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 201 | 3.473 | 0.5492 | Yes |
| 19 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 202 | 3.471 | 0.5739 | Yes |
| 20 | TREX1 | three prime repair exonuclease 1 [Source:HGNC Symbol;Acc:HGNC:12269] | 214 | 3.397 | 0.5978 | Yes |
| 21 | TRIM21 | tripartite motif containing 21 [Source:HGNC Symbol;Acc:HGNC:11312] | 273 | 3.123 | 0.6185 | Yes |
| 22 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 285 | 3.080 | 0.6401 | Yes |
| 23 | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:15925] | 318 | 2.927 | 0.6601 | Yes |
| 24 | MYD88 | MYD88 innate immune signal transduction adaptor [Source:HGNC Symbol;Acc:HGNC:7562] | 322 | 2.909 | 0.6807 | Yes |
| 25 | TDRD7 | tudor domain containing 7 [Source:HGNC Symbol;Acc:HGNC:30831] | 396 | 2.620 | 0.6974 | Yes |
| 26 | TRIM14 | tripartite motif containing 14 [Source:HGNC Symbol;Acc:HGNC:16283] | 403 | 2.596 | 0.7157 | Yes |
| 27 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 520 | 2.305 | 0.7290 | Yes |
| 28 | PSMB9 | proteasome 20S subunit beta 9 [Source:HGNC Symbol;Acc:HGNC:9546] | 527 | 2.297 | 0.7452 | Yes |
| 29 | PSMB8 | proteasome 20S subunit beta 8 [Source:HGNC Symbol;Acc:HGNC:9545] | 582 | 2.169 | 0.7592 | Yes |
| 30 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 606 | 2.135 | 0.7737 | Yes |
| 31 | THEMIS2 | thymocyte selection associated family member 2 [Source:HGNC Symbol;Acc:HGNC:16839] | 608 | 2.134 | 0.7889 | Yes |
| 32 | UBE2L6 | ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490] | 618 | 2.114 | 0.8037 | Yes |
| 33 | HLA-F | major histocompatibility complex, class I, F [Source:HGNC Symbol;Acc:HGNC:4963] | 643 | 2.075 | 0.8178 | Yes |
| 34 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 687 | 2.005 | 0.8309 | Yes |
| 35 | CASP1 | caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499] | 759 | 1.884 | 0.8424 | Yes |
| 36 | BAZ1A | bromodomain adjacent to zinc finger domain 1A [Source:HGNC Symbol;Acc:HGNC:960] | 1114 | 1.462 | 0.8433 | Yes |
| 37 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 1267 | 1.338 | 0.8487 | Yes |
| 38 | SP110 | SP110 nuclear body protein [Source:HGNC Symbol;Acc:HGNC:5401] | 1374 | 1.263 | 0.8548 | Yes |
| 39 | WARS1 | tryptophanyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12729] | 2535 | 0.724 | 0.8287 | No |
| 40 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 3904 | 0.378 | 0.7944 | No |
| 41 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 4523 | 0.265 | 0.7796 | No |
| 42 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 4623 | 0.248 | 0.7787 | No |
| 43 | SP100 | SP100 nuclear antigen [Source:HGNC Symbol;Acc:HGNC:11206] | 5503 | 0.120 | 0.7558 | No |
| 44 | CYTH1 | cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501] | 6258 | 0.015 | 0.7355 | No |
| 45 | TYMP | thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148] | 10216 | 0.000 | 0.6287 | No |
| 46 | IFI30 | IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398] | 11456 | 0.000 | 0.5952 | No |
| 47 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12430 | 0.000 | 0.5689 | No |
| 48 | APOBEC3G | apolipoprotein B mRNA editing enzyme catalytic subunit 3G [Source:HGNC Symbol;Acc:HGNC:17357] | 12454 | 0.000 | 0.5683 | No |
| 49 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12458 | 0.000 | 0.5682 | No |
| 50 | IL15RA | interleukin 15 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5978] | 14095 | 0.000 | 0.5240 | No |
| 51 | TRIM22 | tripartite motif containing 22 [Source:HGNC Symbol;Acc:HGNC:16379] | 15256 | 0.000 | 0.4927 | No |
| 52 | NMI | N-myc and STAT interactor [Source:HGNC Symbol;Acc:HGNC:7854] | 19186 | 0.000 | 0.3866 | No |
| 53 | IDO1 | indoleamine 2,3-dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:6059] | 20032 | 0.000 | 0.3638 | No |
| 54 | IFI6 | interferon alpha inducible protein 6 [Source:HGNC Symbol;Acc:HGNC:4054] | 20543 | 0.000 | 0.3500 | No |
| 55 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22675 | 0.000 | 0.2924 | No |
| 56 | IFIT5 | interferon induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:HGNC:13328] | 22992 | 0.000 | 0.2839 | No |
| 57 | PLAAT4 | phospholipase A and acyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:9869] | 24770 | 0.000 | 0.2359 | No |
| 58 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 26886 | 0.000 | 0.1788 | No |
| 59 | PDZD2 | PDZ domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18486] | 27412 | -0.050 | 0.1649 | No |
| 60 | ZBTB20 | zinc finger and BTB domain containing 20 [Source:HGNC Symbol;Acc:HGNC:13503] | 31299 | -0.607 | 0.0643 | No |
| 61 | RABGAP1L | RAB GTPase activating protein 1 like [Source:HGNC Symbol;Acc:HGNC:24663] | 32131 | -0.793 | 0.0475 | No |
| 62 | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1 [Source:HGNC Symbol;Acc:HGNC:15864] | 32255 | -0.821 | 0.0500 | No |
| 63 | RGL1 | ral guanine nucleotide dissociation stimulator like 1 [Source:HGNC Symbol;Acc:HGNC:30281] | 32369 | -0.851 | 0.0530 | No |
| 64 | KIF5C | kinesin family member 5C [Source:HGNC Symbol;Acc:HGNC:6325] | 34833 | -1.687 | -0.0015 | No |
| 65 | LMO2 | LIM domain only 2 [Source:HGNC Symbol;Acc:HGNC:6642] | 35242 | -1.913 | 0.0011 | No |
| 66 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36586 | -3.138 | -0.0128 | No |
| 67 | GMPR | guanosine monophosphate reductase [Source:HGNC Symbol;Acc:HGNC:4376] | 36880 | -3.710 | 0.0057 | No |
