Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | CROONQUIST_NRAS_SIGNALING_DN |
| Enrichment Score (ES) | -0.848956 |
| Normalized Enrichment Score (NES) | -1.7157505 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SBNO2 | strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158] | 1268 | 1.337 | -0.0260 | No |
| 2 | HMGA1 | high mobility group AT-hook 1 [Source:HGNC Symbol;Acc:HGNC:5010] | 1626 | 1.102 | -0.0289 | No |
| 3 | GNAI1 | G protein subunit alpha i1 [Source:HGNC Symbol;Acc:HGNC:4384] | 2152 | 0.858 | -0.0378 | No |
| 4 | EIF5 | eukaryotic translation initiation factor 5 [Source:HGNC Symbol;Acc:HGNC:3299] | 2274 | 0.811 | -0.0361 | No |
| 5 | SNRPA1 | small nuclear ribonucleoprotein polypeptide A' [Source:HGNC Symbol;Acc:HGNC:11152] | 3064 | 0.566 | -0.0539 | No |
| 6 | MYRF | myelin regulatory factor [Source:HGNC Symbol;Acc:HGNC:1181] | 3781 | 0.406 | -0.0708 | No |
| 7 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12467 | 0.000 | -0.3054 | No |
| 8 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25804 | 0.000 | -0.6656 | No |
| 9 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 31272 | -0.602 | -0.8096 | No |
| 10 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 31585 | -0.666 | -0.8139 | No |
| 11 | PLOD2 | procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 [Source:HGNC Symbol;Acc:HGNC:9082] | 32437 | -0.865 | -0.8316 | No |
| 12 | CSE1L | chromosome segregation 1 like [Source:HGNC Symbol;Acc:HGNC:2431] | 32730 | -0.941 | -0.8337 | No |
| 13 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33245 | -1.087 | -0.8409 | No |
| 14 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33258 | -1.093 | -0.8345 | No |
| 15 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33793 | -1.266 | -0.8412 | Yes |
| 16 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33887 | -1.300 | -0.8357 | Yes |
| 17 | POLD3 | DNA polymerase delta 3, accessory subunit [Source:HGNC Symbol;Acc:HGNC:20932] | 34278 | -1.445 | -0.8374 | Yes |
| 18 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34588 | -1.576 | -0.8360 | Yes |
| 19 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34938 | -1.741 | -0.8348 | Yes |
| 20 | CDC25C | cell division cycle 25C [Source:HGNC Symbol;Acc:HGNC:1727] | 34956 | -1.749 | -0.8245 | Yes |
| 21 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35043 | -1.792 | -0.8158 | Yes |
| 22 | BRD8 | bromodomain containing 8 [Source:HGNC Symbol;Acc:HGNC:19874] | 35047 | -1.793 | -0.8049 | Yes |
| 23 | CHAF1A | chromatin assembly factor 1 subunit A [Source:HGNC Symbol;Acc:HGNC:1910] | 35073 | -1.810 | -0.7944 | Yes |
| 24 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 35148 | -1.850 | -0.7851 | Yes |
| 25 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35386 | -2.005 | -0.7792 | Yes |
| 26 | RAD51C | RAD51 paralog C [Source:HGNC Symbol;Acc:HGNC:9820] | 35456 | -2.055 | -0.7684 | Yes |
| 27 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35573 | -2.135 | -0.7584 | Yes |
| 28 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35579 | -2.138 | -0.7454 | Yes |
| 29 | CDC6 | cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744] | 35675 | -2.217 | -0.7344 | Yes |
| 30 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 35735 | -2.266 | -0.7221 | Yes |
| 31 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35816 | -2.333 | -0.7099 | Yes |
| 32 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35837 | -2.347 | -0.6960 | Yes |
| 33 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35874 | -2.384 | -0.6823 | Yes |
| 34 | CHEK1 | checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925] | 35897 | -2.409 | -0.6682 | Yes |
| 35 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 35899 | -2.411 | -0.6534 | Yes |
| 36 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35901 | -2.411 | -0.6386 | Yes |
| 37 | STIL | STIL centriolar assembly protein [Source:HGNC Symbol;Acc:HGNC:10879] | 35955 | -2.459 | -0.6249 | Yes |
| 38 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36076 | -2.578 | -0.6123 | Yes |
| 39 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 36108 | -2.616 | -0.5971 | Yes |
| 40 | GALE | UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116] | 36127 | -2.643 | -0.5814 | Yes |
| 41 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36139 | -2.657 | -0.5653 | Yes |
| 42 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 36141 | -2.658 | -0.5490 | Yes |
| 43 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 36164 | -2.684 | -0.5332 | Yes |
| 44 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36206 | -2.726 | -0.5175 | Yes |
| 45 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 36261 | -2.777 | -0.5019 | Yes |
| 46 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36279 | -2.795 | -0.4852 | Yes |
| 47 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36339 | -2.870 | -0.4692 | Yes |
| 48 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36371 | -2.891 | -0.4523 | Yes |
| 49 | TRAIP | TRAF interacting protein [Source:HGNC Symbol;Acc:HGNC:30764] | 36449 | -2.976 | -0.4361 | Yes |
| 50 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36483 | -3.006 | -0.4185 | Yes |
| 51 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36491 | -3.015 | -0.4002 | Yes |
| 52 | GPX4 | glutathione peroxidase 4 [Source:HGNC Symbol;Acc:HGNC:4556] | 36555 | -3.099 | -0.3828 | Yes |
| 53 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36592 | -3.140 | -0.3645 | Yes |
| 54 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36611 | -3.176 | -0.3455 | Yes |
| 55 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36630 | -3.207 | -0.3263 | Yes |
| 56 | SPC25 | SPC25 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24031] | 36665 | -3.258 | -0.3072 | Yes |
| 57 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36667 | -3.270 | -0.2872 | Yes |
| 58 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 36692 | -3.321 | -0.2674 | Yes |
| 59 | PTP4A3 | protein tyrosine phosphatase 4A3 [Source:HGNC Symbol;Acc:HGNC:9636] | 36707 | -3.354 | -0.2472 | Yes |
| 60 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36709 | -3.356 | -0.2266 | Yes |
| 61 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 36770 | -3.470 | -0.2069 | Yes |
| 62 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36833 | -3.603 | -0.1865 | Yes |
| 63 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36868 | -3.675 | -0.1648 | Yes |
| 64 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36876 | -3.698 | -0.1423 | Yes |
| 65 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36917 | -3.817 | -0.1199 | Yes |
| 66 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36922 | -3.842 | -0.0964 | Yes |
| 67 | CHEK2 | checkpoint kinase 2 [Source:HGNC Symbol;Acc:HGNC:16627] | 36929 | -3.880 | -0.0728 | Yes |
| 68 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36955 | -3.967 | -0.0491 | Yes |
| 69 | WEE1 | WEE1 G2 checkpoint kinase [Source:HGNC Symbol;Acc:HGNC:12761] | 36989 | -4.089 | -0.0249 | Yes |
| 70 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37060 | -4.490 | 0.0008 | Yes |
