Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | HECKER_IFNB1_TARGETS |
| Enrichment Score (ES) | 0.89823645 |
| Normalized Enrichment Score (NES) | 2.2448814 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 6 | 4.960 | 0.0327 | Yes |
| 2 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 8 | 4.948 | 0.0655 | Yes |
| 3 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 23 | 4.827 | 0.0971 | Yes |
| 4 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 24 | 4.813 | 0.1291 | Yes |
| 5 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 31 | 4.755 | 0.1604 | Yes |
| 6 | OASL | 2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] | 33 | 4.742 | 0.1918 | Yes |
| 7 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 35 | 4.721 | 0.2231 | Yes |
| 8 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 48 | 4.592 | 0.2533 | Yes |
| 9 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 55 | 4.511 | 0.2830 | Yes |
| 10 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 56 | 4.507 | 0.3129 | Yes |
| 11 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [Source:HGNC Symbol;Acc:HGNC:26072] | 59 | 4.474 | 0.3425 | Yes |
| 12 | DHX58 | DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517] | 64 | 4.416 | 0.3717 | Yes |
| 13 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 82 | 4.215 | 0.3992 | Yes |
| 14 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 85 | 4.196 | 0.4269 | Yes |
| 15 | DDX58 | DExD/H-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:19102] | 100 | 4.102 | 0.4538 | Yes |
| 16 | SIGLEC1 | sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127] | 108 | 4.052 | 0.4804 | Yes |
| 17 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 112 | 4.003 | 0.5069 | Yes |
| 18 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 134 | 3.887 | 0.5321 | Yes |
| 19 | SAMD9 | sterile alpha motif domain containing 9 [Source:HGNC Symbol;Acc:HGNC:1348] | 139 | 3.871 | 0.5577 | Yes |
| 20 | PARP12 | poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919] | 140 | 3.863 | 0.5833 | Yes |
| 21 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 144 | 3.824 | 0.6086 | Yes |
| 22 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 149 | 3.787 | 0.6336 | Yes |
| 23 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 160 | 3.711 | 0.6579 | Yes |
| 24 | EPSTI1 | epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] | 167 | 3.662 | 0.6820 | Yes |
| 25 | STAP1 | signal transducing adaptor family member 1 [Source:HGNC Symbol;Acc:HGNC:24133] | 193 | 3.520 | 0.7047 | Yes |
| 26 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 198 | 3.495 | 0.7278 | Yes |
| 27 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 213 | 3.401 | 0.7499 | Yes |
| 28 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 254 | 3.217 | 0.7702 | Yes |
| 29 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 285 | 3.080 | 0.7898 | Yes |
| 30 | PNPT1 | polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166] | 292 | 3.064 | 0.8099 | Yes |
| 31 | PARP9 | poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118] | 309 | 2.964 | 0.8292 | Yes |
| 32 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 474 | 2.407 | 0.8407 | Yes |
| 33 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 520 | 2.305 | 0.8548 | Yes |
| 34 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 606 | 2.135 | 0.8666 | Yes |
| 35 | DTX3L | deltex E3 ubiquitin ligase 3L [Source:HGNC Symbol;Acc:HGNC:30323] | 681 | 2.018 | 0.8780 | Yes |
| 36 | PDZK1IP1 | PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887] | 874 | 1.693 | 0.8840 | Yes |
| 37 | LAP3 | leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] | 1012 | 1.542 | 0.8906 | Yes |
| 38 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 1156 | 1.433 | 0.8962 | Yes |
| 39 | SH3BGRL2 | SH3 domain binding glutamate rich protein like 2 [Source:HGNC Symbol;Acc:HGNC:15567] | 1389 | 1.252 | 0.8982 | Yes |
| 40 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 1842 | 0.989 | 0.8926 | No |
| 41 | MYL9 | myosin light chain 9 [Source:HGNC Symbol;Acc:HGNC:15754] | 2462 | 0.745 | 0.8808 | No |
| 42 | ITGA2B | integrin subunit alpha 2b [Source:HGNC Symbol;Acc:HGNC:6138] | 2868 | 0.617 | 0.8739 | No |
| 43 | HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 [Source:HGNC Symbol;Acc:HGNC:24368] | 2985 | 0.582 | 0.8747 | No |
| 44 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 3097 | 0.559 | 0.8754 | No |
| 45 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 3904 | 0.378 | 0.8561 | No |
| 46 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 4195 | 0.324 | 0.8504 | No |
| 47 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 4523 | 0.265 | 0.8433 | No |
| 48 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 4623 | 0.248 | 0.8423 | No |
| 49 | MMP25 | matrix metallopeptidase 25 [Source:HGNC Symbol;Acc:HGNC:14246] | 4710 | 0.234 | 0.8415 | No |
| 50 | CYP4F3 | cytochrome P450 family 4 subfamily F member 3 [Source:HGNC Symbol;Acc:HGNC:2646] | 4760 | 0.225 | 0.8417 | No |
| 51 | HES4 | hes family bHLH transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:24149] | 7210 | 0.000 | 0.7755 | No |
| 52 | ARG1 | arginase 1 [Source:HGNC Symbol;Acc:HGNC:663] | 7306 | 0.000 | 0.7729 | No |
| 53 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 7733 | 0.000 | 0.7614 | No |
| 54 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 9164 | 0.000 | 0.7228 | No |
| 55 | FCER1A | Fc fragment of IgE receptor Ia [Source:HGNC Symbol;Acc:HGNC:3609] | 9888 | 0.000 | 0.7032 | No |
| 56 | TYMP | thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148] | 10216 | 0.000 | 0.6944 | No |
| 57 | RTP4 | receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992] | 10503 | 0.000 | 0.6867 | No |
| 58 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12122 | 0.000 | 0.6429 | No |
| 59 | APOBEC3A | apolipoprotein B mRNA editing enzyme catalytic subunit 3A [Source:HGNC Symbol;Acc:HGNC:17343] | 12465 | 0.000 | 0.6337 | No |
| 60 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12467 | 0.000 | 0.6337 | No |
| 61 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 13043 | 0.000 | 0.6181 | No |
| 62 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 15793 | 0.000 | 0.5438 | No |
| 63 | GP9 | glycoprotein IX platelet [Source:HGNC Symbol;Acc:HGNC:4444] | 17052 | 0.000 | 0.5098 | No |
| 64 | SERPING1 | serpin family G member 1 [Source:HGNC Symbol;Acc:HGNC:1228] | 17676 | 0.000 | 0.4930 | No |
| 65 | SPON2 | spondin 2 [Source:HGNC Symbol;Acc:HGNC:11253] | 18820 | 0.000 | 0.4621 | No |
| 66 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19309 | 0.000 | 0.4489 | No |
| 67 | CHI3L1 | chitinase 3 like 1 [Source:HGNC Symbol;Acc:HGNC:1932] | 19698 | 0.000 | 0.4384 | No |
| 68 | C1QB | complement C1q B chain [Source:HGNC Symbol;Acc:HGNC:1242] | 19968 | 0.000 | 0.4311 | No |
| 69 | C1QA | complement C1q A chain [Source:HGNC Symbol;Acc:HGNC:1241] | 19969 | 0.000 | 0.4311 | No |
| 70 | C1QC | complement C1q C chain [Source:HGNC Symbol;Acc:HGNC:1245] | 19984 | 0.000 | 0.4308 | No |
| 71 | FFAR2 | free fatty acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:4501] | 20530 | 0.000 | 0.4160 | No |
| 72 | IFI6 | interferon alpha inducible protein 6 [Source:HGNC Symbol;Acc:HGNC:4054] | 20543 | 0.000 | 0.4157 | No |
| 73 | CMTM5 | CKLF like MARVEL transmembrane domain containing 5 [Source:HGNC Symbol;Acc:HGNC:19176] | 21846 | 0.000 | 0.3805 | No |
| 74 | CMTM2 | CKLF like MARVEL transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19173] | 21859 | 0.000 | 0.3802 | No |
| 75 | TRBV27 | T cell receptor beta variable 27 [Source:HGNC Symbol;Acc:HGNC:12208] | 22440 | 0.000 | 0.3645 | No |
| 76 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22675 | 0.000 | 0.3582 | No |
| 77 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22684 | 0.000 | 0.3580 | No |
| 78 | IFIT5 | interferon induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:HGNC:13328] | 22992 | 0.000 | 0.3497 | No |
| 79 | KCNJ15 | potassium inwardly rectifying channel subfamily J member 15 [Source:HGNC Symbol;Acc:HGNC:6261] | 23599 | 0.000 | 0.3333 | No |
| 80 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 23675 | 0.000 | 0.3313 | No |
| 81 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 24238 | 0.000 | 0.3161 | No |
| 82 | CABP5 | calcium binding protein 5 [Source:HGNC Symbol;Acc:HGNC:13714] | 24485 | 0.000 | 0.3094 | No |
| 83 | ZBP1 | Z-DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:16176] | 25572 | 0.000 | 0.2801 | No |
| 84 | MS4A4A | membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371] | 25691 | 0.000 | 0.2769 | No |
| 85 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 26886 | 0.000 | 0.2446 | No |
| 86 | RPS23 | ribosomal protein S23 [Source:HGNC Symbol;Acc:HGNC:10410] | 29504 | -0.325 | 0.1760 | No |
| 87 | SCO2 | synthesis of cytochrome C oxidase 2 [Source:HGNC Symbol;Acc:HGNC:10604] | 29607 | -0.341 | 0.1755 | No |
| 88 | TREML1 | triggering receptor expressed on myeloid cells like 1 [Source:HGNC Symbol;Acc:HGNC:20434] | 30906 | -0.541 | 0.1440 | No |
| 89 | JUP | junction plakoglobin [Source:HGNC Symbol;Acc:HGNC:6207] | 31244 | -0.597 | 0.1389 | No |
| 90 | MGAM | maltase-glucoamylase [Source:HGNC Symbol;Acc:HGNC:7043] | 32075 | -0.780 | 0.1216 | No |
| 91 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 32277 | -0.825 | 0.1217 | No |
| 92 | PROS1 | protein S [Source:HGNC Symbol;Acc:HGNC:9456] | 33784 | -1.263 | 0.0894 | No |
