Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | ISHIDA_E2F_TARGETS |
| Enrichment Score (ES) | -0.8795691 |
| Normalized Enrichment Score (NES) | -1.701201 |
| Nominal p-value | 0.0 |
| FDR q-value | 6.0963517E-5 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ANXA8L1 | annexin A8 like 1 [Source:HGNC Symbol;Acc:HGNC:23334] | 21890 | 0.000 | -0.5910 | No |
| 2 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 31585 | -0.666 | -0.8477 | No |
| 3 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 32355 | -0.847 | -0.8621 | No |
| 4 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 32439 | -0.866 | -0.8578 | No |
| 5 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33245 | -1.087 | -0.8714 | Yes |
| 6 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33258 | -1.093 | -0.8635 | Yes |
| 7 | CDT1 | chromatin licensing and DNA replication factor 1 [Source:HGNC Symbol;Acc:HGNC:24576] | 33599 | -1.201 | -0.8637 | Yes |
| 8 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33793 | -1.266 | -0.8594 | Yes |
| 9 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33887 | -1.300 | -0.8521 | Yes |
| 10 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 34079 | -1.367 | -0.8470 | Yes |
| 11 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 34333 | -1.473 | -0.8428 | Yes |
| 12 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 34963 | -1.752 | -0.8466 | Yes |
| 13 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35043 | -1.792 | -0.8353 | Yes |
| 14 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 35063 | -1.804 | -0.8223 | Yes |
| 15 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 35120 | -1.833 | -0.8100 | Yes |
| 16 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 35735 | -2.266 | -0.8096 | Yes |
| 17 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 35868 | -2.378 | -0.7953 | Yes |
| 18 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35901 | -2.411 | -0.7780 | Yes |
| 19 | SGO1 | shugoshin 1 [Source:HGNC Symbol;Acc:HGNC:25088] | 36030 | -2.528 | -0.7625 | Yes |
| 20 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 36079 | -2.583 | -0.7444 | Yes |
| 21 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36187 | -2.707 | -0.7270 | Yes |
| 22 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 36261 | -2.777 | -0.7081 | Yes |
| 23 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 36266 | -2.780 | -0.6873 | Yes |
| 24 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 36267 | -2.781 | -0.6664 | Yes |
| 25 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36339 | -2.870 | -0.6468 | Yes |
| 26 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 36346 | -2.873 | -0.6254 | Yes |
| 27 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36371 | -2.891 | -0.6043 | Yes |
| 28 | LBR | lamin B receptor [Source:HGNC Symbol;Acc:HGNC:6518] | 36420 | -2.952 | -0.5835 | Yes |
| 29 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36425 | -2.957 | -0.5614 | Yes |
| 30 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36491 | -3.015 | -0.5405 | Yes |
| 31 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36591 | -3.140 | -0.5196 | Yes |
| 32 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36592 | -3.140 | -0.4960 | Yes |
| 33 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36606 | -3.169 | -0.4726 | Yes |
| 34 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36622 | -3.191 | -0.4490 | Yes |
| 35 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36630 | -3.207 | -0.4251 | Yes |
| 36 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36667 | -3.270 | -0.4015 | Yes |
| 37 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36680 | -3.288 | -0.3771 | Yes |
| 38 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36695 | -3.325 | -0.3526 | Yes |
| 39 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36709 | -3.356 | -0.3277 | Yes |
| 40 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36724 | -3.390 | -0.3026 | Yes |
| 41 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 36770 | -3.470 | -0.2778 | Yes |
| 42 | ANLN | anillin actin binding protein [Source:HGNC Symbol;Acc:HGNC:14082] | 36818 | -3.574 | -0.2522 | Yes |
| 43 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36833 | -3.603 | -0.2255 | Yes |
| 44 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36863 | -3.662 | -0.1988 | Yes |
| 45 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36868 | -3.675 | -0.1713 | Yes |
| 46 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36870 | -3.679 | -0.1437 | Yes |
| 47 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36891 | -3.747 | -0.1161 | Yes |
| 48 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36916 | -3.817 | -0.0881 | Yes |
| 49 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36935 | -3.893 | -0.0594 | Yes |
| 50 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36955 | -3.967 | -0.0301 | Yes |
| 51 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37060 | -4.490 | 0.0008 | Yes |
