Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | KONG_E2F3_TARGETS |
| Enrichment Score (ES) | -0.83973426 |
| Normalized Enrichment Score (NES) | -1.7315972 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GAS5 | growth arrest specific 5 [Source:HGNC Symbol;Acc:HGNC:16355] | 1221 | 1.374 | -0.0259 | No |
| 2 | NR1D1 | nuclear receptor subfamily 1 group D member 1 [Source:HGNC Symbol;Acc:HGNC:7962] | 1488 | 1.181 | -0.0270 | No |
| 3 | E2F3 | E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115] | 1924 | 0.946 | -0.0339 | No |
| 4 | SRSF7 | serine and arginine rich splicing factor 7 [Source:HGNC Symbol;Acc:HGNC:10789] | 2059 | 0.892 | -0.0329 | No |
| 5 | IGF2BP1 | insulin like growth factor 2 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:28866] | 3116 | 0.555 | -0.0586 | No |
| 6 | MED1 | mediator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:9234] | 3246 | 0.520 | -0.0594 | No |
| 7 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 3730 | 0.414 | -0.0703 | No |
| 8 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 4156 | 0.331 | -0.0801 | No |
| 9 | NUP50 | nucleoporin 50 [Source:HGNC Symbol;Acc:HGNC:8065] | 5384 | 0.137 | -0.1126 | No |
| 10 | TAL2 | TAL bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11557] | 6143 | 0.032 | -0.1329 | No |
| 11 | H4C15 | H4 clustered histone 15 [Source:HGNC Symbol;Acc:HGNC:29607] | 12641 | 0.000 | -0.3085 | No |
| 12 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16663 | 0.000 | -0.4172 | No |
| 13 | MYB | MYB proto-oncogene, transcription factor [Source:HGNC Symbol;Acc:HGNC:7545] | 19032 | 0.000 | -0.4812 | No |
| 14 | PRL | prolactin [Source:HGNC Symbol;Acc:HGNC:9445] | 19957 | 0.000 | -0.5062 | No |
| 15 | PSORS1C2 | psoriasis susceptibility 1 candidate 2 [Source:HGNC Symbol;Acc:HGNC:17199] | 20602 | 0.000 | -0.5236 | No |
| 16 | F13A1 | coagulation factor XIII A chain [Source:HGNC Symbol;Acc:HGNC:3531] | 22575 | 0.000 | -0.5769 | No |
| 17 | GP1BA | glycoprotein Ib platelet subunit alpha [Source:HGNC Symbol;Acc:HGNC:4439] | 23034 | 0.000 | -0.5893 | No |
| 18 | FBXO45 | F-box protein 45 [Source:HGNC Symbol;Acc:HGNC:29148] | 28880 | -0.239 | -0.7460 | No |
| 19 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29215 | -0.283 | -0.7536 | No |
| 20 | MAPK8 | mitogen-activated protein kinase 8 [Source:HGNC Symbol;Acc:HGNC:6881] | 29409 | -0.314 | -0.7572 | No |
| 21 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 30241 | -0.434 | -0.7774 | No |
| 22 | RPL12 | ribosomal protein L12 [Source:HGNC Symbol;Acc:HGNC:10302] | 30653 | -0.499 | -0.7860 | No |
| 23 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 30731 | -0.511 | -0.7854 | No |
| 24 | RPRD1B | regulation of nuclear pre-mRNA domain containing 1B [Source:HGNC Symbol;Acc:HGNC:16209] | 30912 | -0.542 | -0.7875 | No |
| 25 | TAF1D | TATA-box binding protein associated factor, RNA polymerase I subunit D [Source:HGNC Symbol;Acc:HGNC:28759] | 32404 | -0.860 | -0.8233 | No |
| 26 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 32718 | -0.936 | -0.8270 | No |
| 27 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32856 | -0.976 | -0.8256 | No |
| 28 | CBX2 | chromobox 2 [Source:HGNC Symbol;Acc:HGNC:1552] | 32969 | -1.006 | -0.8235 | No |
| 29 | HLX | H2.0 like homeobox [Source:HGNC Symbol;Acc:HGNC:4978] | 33572 | -1.193 | -0.8336 | Yes |
| 30 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33793 | -1.266 | -0.8330 | Yes |
| 31 | FAM111A | family with sequence similarity 111 member A [Source:HGNC Symbol;Acc:HGNC:24725] | 33810 | -1.273 | -0.8269 | Yes |
| 32 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 34079 | -1.367 | -0.8270 | Yes |
| 33 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 34252 | -1.433 | -0.8243 | Yes |
| 34 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 34311 | -1.461 | -0.8183 | Yes |
| 35 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 34333 | -1.473 | -0.8113 | Yes |
| 36 | CDC7 | cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745] | 34380 | -1.492 | -0.8048 | Yes |
| 37 | CENPQ | centromere protein Q [Source:HGNC Symbol;Acc:HGNC:21347] | 34493 | -1.537 | -0.7999 | Yes |
| 38 | RBL1 | RB transcriptional corepressor like 1 [Source:HGNC Symbol;Acc:HGNC:9893] | 34541 | -1.558 | -0.7931 | Yes |
| 39 | RBBP8 | RB binding protein 8, endonuclease [Source:HGNC Symbol;Acc:HGNC:9891] | 34577 | -1.572 | -0.7860 | Yes |
| 40 | RPL3 | ribosomal protein L3 [Source:HGNC Symbol;Acc:HGNC:10332] | 34892 | -1.713 | -0.7856 | Yes |
| 41 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34938 | -1.741 | -0.7778 | Yes |
| 42 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 34963 | -1.752 | -0.7695 | Yes |
| 43 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35043 | -1.792 | -0.7623 | Yes |
| 44 | USP1 | ubiquitin specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:12607] | 35179 | -1.867 | -0.7564 | Yes |
| 45 | DEPDC1 | DEP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22949] | 35388 | -2.006 | -0.7516 | Yes |
| 46 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 35484 | -2.073 | -0.7435 | Yes |
| 47 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35573 | -2.135 | -0.7349 | Yes |
| 48 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35579 | -2.138 | -0.7240 | Yes |
| 49 | CDC6 | cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744] | 35675 | -2.217 | -0.7151 | Yes |
| 50 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 35735 | -2.266 | -0.7050 | Yes |
| 51 | ERCC6L | ERCC excision repair 6 like, spindle assembly checkpoint helicase [Source:HGNC Symbol;Acc:HGNC:20794] | 35759 | -2.287 | -0.6938 | Yes |
| 52 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35816 | -2.333 | -0.6833 | Yes |
| 53 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35837 | -2.347 | -0.6717 | Yes |
| 54 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35901 | -2.411 | -0.6609 | Yes |
| 55 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 35923 | -2.431 | -0.6490 | Yes |
| 56 | SPDL1 | spindle apparatus coiled-coil protein 1 [Source:HGNC Symbol;Acc:HGNC:26010] | 35981 | -2.483 | -0.6377 | Yes |
| 57 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 36079 | -2.583 | -0.6270 | Yes |
| 58 | NCAPG2 | non-SMC condensin II complex subunit G2 [Source:HGNC Symbol;Acc:HGNC:21904] | 36148 | -2.663 | -0.6151 | Yes |
| 59 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 36174 | -2.692 | -0.6019 | Yes |
| 60 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36187 | -2.707 | -0.5882 | Yes |
| 61 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36206 | -2.726 | -0.5746 | Yes |
| 62 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 36227 | -2.746 | -0.5610 | Yes |
| 63 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 36266 | -2.780 | -0.5477 | Yes |
| 64 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36279 | -2.795 | -0.5336 | Yes |
| 65 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 36300 | -2.818 | -0.5196 | Yes |
| 66 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36303 | -2.820 | -0.5051 | Yes |
| 67 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36339 | -2.870 | -0.4912 | Yes |
| 68 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 36346 | -2.873 | -0.4765 | Yes |
| 69 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36358 | -2.884 | -0.4619 | Yes |
| 70 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36371 | -2.891 | -0.4473 | Yes |
| 71 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36376 | -2.899 | -0.4325 | Yes |
| 72 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36383 | -2.908 | -0.4176 | Yes |
| 73 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 36418 | -2.951 | -0.4033 | Yes |
| 74 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 36430 | -2.964 | -0.3883 | Yes |
| 75 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36483 | -3.006 | -0.3742 | Yes |
| 76 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 36516 | -3.057 | -0.3593 | Yes |
| 77 | FIGNL1 | fidgetin like 1 [Source:HGNC Symbol;Acc:HGNC:13286] | 36523 | -3.064 | -0.3436 | Yes |
| 78 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36535 | -3.075 | -0.3281 | Yes |
| 79 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 36576 | -3.129 | -0.3130 | Yes |
| 80 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36586 | -3.138 | -0.2970 | Yes |
| 81 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36591 | -3.140 | -0.2809 | Yes |
| 82 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36592 | -3.140 | -0.2647 | Yes |
| 83 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36611 | -3.176 | -0.2488 | Yes |
| 84 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36622 | -3.191 | -0.2326 | Yes |
| 85 | SPC25 | SPC25 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24031] | 36665 | -3.258 | -0.2169 | Yes |
| 86 | PSIP1 | PC4 and SFRS1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9527] | 36675 | -3.284 | -0.2002 | Yes |
| 87 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36709 | -3.356 | -0.1838 | Yes |
| 88 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36724 | -3.390 | -0.1667 | Yes |
| 89 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36811 | -3.559 | -0.1506 | Yes |
| 90 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36857 | -3.648 | -0.1330 | Yes |
| 91 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 36862 | -3.659 | -0.1142 | Yes |
| 92 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36868 | -3.675 | -0.0954 | Yes |
| 93 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36870 | -3.679 | -0.0764 | Yes |
| 94 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36882 | -3.715 | -0.0576 | Yes |
| 95 | BRCA1 | BRCA1 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1100] | 36897 | -3.766 | -0.0385 | Yes |
| 96 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36955 | -3.967 | -0.0196 | Yes |
| 97 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37060 | -4.490 | 0.0008 | Yes |
