Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | MORI_IMMATURE_B_LYMPHOCYTE_DN |
| Enrichment Score (ES) | -0.8325555 |
| Normalized Enrichment Score (NES) | -1.7069353 |
| Nominal p-value | 0.0 |
| FDR q-value | 7.9252575E-5 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434] | 1696 | 1.057 | -0.0401 | No |
| 2 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 1913 | 0.953 | -0.0408 | No |
| 3 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 2429 | 0.759 | -0.0506 | No |
| 4 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 2534 | 0.725 | -0.0495 | No |
| 5 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 2687 | 0.672 | -0.0500 | No |
| 6 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 3730 | 0.414 | -0.0759 | No |
| 7 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 4156 | 0.331 | -0.0856 | No |
| 8 | PREP | prolyl endopeptidase [Source:HGNC Symbol;Acc:HGNC:9358] | 4260 | 0.310 | -0.0867 | No |
| 9 | RAG1 | recombination activating 1 [Source:HGNC Symbol;Acc:HGNC:9831] | 12512 | 0.000 | -0.3097 | No |
| 10 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16663 | 0.000 | -0.4219 | No |
| 11 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18322 | 0.000 | -0.4667 | No |
| 12 | RAMP1 | receptor activity modifying protein 1 [Source:HGNC Symbol;Acc:HGNC:9843] | 20183 | 0.000 | -0.5170 | No |
| 13 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 26724 | 0.000 | -0.6937 | No |
| 14 | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 [Source:HGNC Symbol;Acc:HGNC:11101] | 27640 | -0.073 | -0.7181 | No |
| 15 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29215 | -0.283 | -0.7591 | No |
| 16 | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100] | 29961 | -0.391 | -0.7771 | No |
| 17 | ACTN4 | actinin alpha 4 [Source:HGNC Symbol;Acc:HGNC:166] | 30048 | -0.404 | -0.7772 | No |
| 18 | CBX1 | chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551] | 30674 | -0.502 | -0.7914 | No |
| 19 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 31053 | -0.567 | -0.7986 | No |
| 20 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 31243 | -0.597 | -0.8004 | No |
| 21 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 31272 | -0.602 | -0.7979 | No |
| 22 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 32355 | -0.847 | -0.8226 | No |
| 23 | HAUS3 | HAUS augmin like complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:28719] | 32723 | -0.939 | -0.8274 | Yes |
| 24 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 32913 | -0.991 | -0.8272 | Yes |
| 25 | PCK2 | phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725] | 33003 | -1.017 | -0.8241 | Yes |
| 26 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33245 | -1.087 | -0.8247 | Yes |
| 27 | HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 [Source:HGNC Symbol;Acc:HGNC:24941] | 33262 | -1.095 | -0.8193 | Yes |
| 28 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 33394 | -1.135 | -0.8167 | Yes |
| 29 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 33447 | -1.152 | -0.8118 | Yes |
| 30 | RBBP4 | RB binding protein 4, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9887] | 33550 | -1.187 | -0.8082 | Yes |
| 31 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33793 | -1.266 | -0.8079 | Yes |
| 32 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33887 | -1.300 | -0.8034 | Yes |
| 33 | UCK2 | uridine-cytidine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12562] | 33935 | -1.318 | -0.7975 | Yes |
| 34 | LGALS1 | galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561] | 33993 | -1.340 | -0.7918 | Yes |
| 35 | SLC16A1 | solute carrier family 16 member 1 [Source:HGNC Symbol;Acc:HGNC:10922] | 34136 | -1.387 | -0.7881 | Yes |
| 36 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 34252 | -1.433 | -0.7835 | Yes |
| 37 | HMGB1 | high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983] | 34443 | -1.518 | -0.7804 | Yes |
| 38 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 34963 | -1.752 | -0.7850 | Yes |
| 39 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35043 | -1.792 | -0.7774 | Yes |
| 40 | CKAP5 | cytoskeleton associated protein 5 [Source:HGNC Symbol;Acc:HGNC:28959] | 35058 | -1.801 | -0.7681 | Yes |
| 41 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 35063 | -1.804 | -0.7584 | Yes |
| 42 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 35148 | -1.850 | -0.7507 | Yes |
| 43 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 35345 | -1.974 | -0.7453 | Yes |
| 44 | XRCC6 | X-ray repair cross complementing 6 [Source:HGNC Symbol;Acc:HGNC:4055] | 35393 | -2.008 | -0.7357 | Yes |
| 45 | TUBA1B | tubulin alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809] | 35542 | -2.109 | -0.7283 | Yes |
| 46 | CENPL | centromere protein L [Source:HGNC Symbol;Acc:HGNC:17879] | 35664 | -2.208 | -0.7196 | Yes |
| 47 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 35735 | -2.266 | -0.7093 | Yes |
| 48 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35874 | -2.384 | -0.7001 | Yes |
| 49 | CHEK1 | checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925] | 35897 | -2.409 | -0.6877 | Yes |
| 50 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35901 | -2.411 | -0.6747 | Yes |
| 51 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36000 | -2.501 | -0.6639 | Yes |
| 52 | TUBB | tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778] | 36013 | -2.511 | -0.6506 | Yes |
| 53 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36076 | -2.578 | -0.6383 | Yes |
| 54 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 36079 | -2.583 | -0.6244 | Yes |
| 55 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 36108 | -2.616 | -0.6110 | Yes |
| 56 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 36174 | -2.692 | -0.5982 | Yes |
| 57 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36206 | -2.726 | -0.5843 | Yes |
| 58 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 36266 | -2.780 | -0.5709 | Yes |
| 59 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 36267 | -2.781 | -0.5559 | Yes |
| 60 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36279 | -2.795 | -0.5411 | Yes |
| 61 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 36300 | -2.818 | -0.5264 | Yes |
| 62 | KIFC1 | kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389] | 36332 | -2.865 | -0.5117 | Yes |
| 63 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36339 | -2.870 | -0.4964 | Yes |
| 64 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36358 | -2.884 | -0.4812 | Yes |
| 65 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36371 | -2.891 | -0.4659 | Yes |
| 66 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36425 | -2.957 | -0.4514 | Yes |
| 67 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36491 | -3.015 | -0.4368 | Yes |
| 68 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36535 | -3.075 | -0.4214 | Yes |
| 69 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36586 | -3.138 | -0.4058 | Yes |
| 70 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36592 | -3.140 | -0.3889 | Yes |
| 71 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36607 | -3.171 | -0.3722 | Yes |
| 72 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36622 | -3.191 | -0.3553 | Yes |
| 73 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36630 | -3.207 | -0.3381 | Yes |
| 74 | GSN | gelsolin [Source:HGNC Symbol;Acc:HGNC:4620] | 36652 | -3.230 | -0.3212 | Yes |
| 75 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36667 | -3.270 | -0.3039 | Yes |
| 76 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36674 | -3.282 | -0.2863 | Yes |
| 77 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36680 | -3.288 | -0.2687 | Yes |
| 78 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36695 | -3.325 | -0.2511 | Yes |
| 79 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36709 | -3.356 | -0.2333 | Yes |
| 80 | PTGR1 | prostaglandin reductase 1 [Source:HGNC Symbol;Acc:HGNC:18429] | 36730 | -3.399 | -0.2155 | Yes |
| 81 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003] | 36790 | -3.513 | -0.1981 | Yes |
| 82 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36821 | -3.579 | -0.1795 | Yes |
| 83 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36863 | -3.662 | -0.1608 | Yes |
| 84 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36870 | -3.679 | -0.1411 | Yes |
| 85 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36891 | -3.747 | -0.1214 | Yes |
| 86 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36894 | -3.758 | -0.1011 | Yes |
| 87 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36922 | -3.842 | -0.0811 | Yes |
| 88 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36935 | -3.893 | -0.0604 | Yes |
| 89 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36949 | -3.950 | -0.0393 | Yes |
| 90 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36955 | -3.967 | -0.0180 | Yes |
| 91 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36971 | -4.005 | 0.0032 | Yes |
