Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | REACTOME_FCGR_ACTIVATION |
| Enrichment Score (ES) | 0.8895378 |
| Normalized Enrichment Score (NES) | 2.2026172 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | FGR | FGR proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3697] | 219 | 3.368 | 0.1840 | Yes |
| 2 | HCK | HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] | 229 | 3.311 | 0.3704 | Yes |
| 3 | SRC | SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283] | 333 | 2.867 | 0.5292 | Yes |
| 4 | LYN | LYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6735] | 341 | 2.816 | 0.6878 | Yes |
| 5 | FCGR2A | Fc fragment of IgG receptor IIa [Source:HGNC Symbol;Acc:HGNC:3616] | 478 | 2.400 | 0.8195 | Yes |
| 6 | FYN | FYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4037] | 1770 | 1.022 | 0.8422 | Yes |
| 7 | SYK | spleen associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11491] | 2370 | 0.775 | 0.8698 | Yes |
| 8 | FCGR1A | Fc fragment of IgG receptor Ia [Source:HGNC Symbol;Acc:HGNC:3613] | 3513 | 0.458 | 0.8647 | Yes |
| 9 | YES1 | YES proto-oncogene 1, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:12841] | 3539 | 0.452 | 0.8895 | Yes |
| 10 | CD247 | CD247 molecule [Source:HGNC Symbol;Acc:HGNC:1677] | 4504 | 0.268 | 0.8786 | No |
| 11 | IGHV2-70 | immunoglobulin heavy variable 2-70 [Source:HGNC Symbol;Acc:HGNC:5577] | 6508 | 0.000 | 0.8245 | No |
| 12 | IGHV1-69 | immunoglobulin heavy variable 1-69 [Source:HGNC Symbol;Acc:HGNC:5558] | 7271 | 0.000 | 0.8039 | No |
| 13 | IGHV1-46 | immunoglobulin heavy variable 1-46 [Source:HGNC Symbol;Acc:HGNC:5554] | 7300 | 0.000 | 0.8031 | No |
| 14 | IGLV7-43 | immunoglobulin lambda variable 7-43 [Source:HGNC Symbol;Acc:HGNC:5929] | 7928 | 0.000 | 0.7862 | No |
| 15 | IGKV2-28 | immunoglobulin kappa variable 2-28 [Source:HGNC Symbol;Acc:HGNC:5783] | 7938 | 0.000 | 0.7860 | No |
| 16 | IGKV2-30 | immunoglobulin kappa variable 2-30 [Source:HGNC Symbol;Acc:HGNC:5785] | 7948 | 0.000 | 0.7857 | No |
| 17 | IGHV3-7 | immunoglobulin heavy variable 3-7 [Source:HGNC Symbol;Acc:HGNC:5620] | 9107 | 0.000 | 0.7544 | No |
| 18 | IGHV4-59 | immunoglobulin heavy variable 4-59 [Source:HGNC Symbol;Acc:HGNC:5654] | 11130 | 0.000 | 0.6998 | No |
| 19 | IGHV4-34 | immunoglobulin heavy variable 4-34 [Source:HGNC Symbol;Acc:HGNC:5650] | 11143 | 0.000 | 0.6995 | No |
| 20 | IGHV4-39 | immunoglobulin heavy variable 4-39 [Source:HGNC Symbol;Acc:HGNC:5651] | 11144 | 0.000 | 0.6995 | No |
| 21 | FCGR3A | Fc fragment of IgG receptor IIIa [Source:HGNC Symbol;Acc:HGNC:3619] | 11414 | 0.000 | 0.6922 | No |
| 22 | IGLV3-19 | immunoglobulin lambda variable 3-19 [Source:HGNC Symbol;Acc:HGNC:5903] | 11687 | 0.000 | 0.6849 | No |
| 23 | IGLV3-25 | immunoglobulin lambda variable 3-25 [Source:HGNC Symbol;Acc:HGNC:5908] | 11691 | 0.000 | 0.6848 | No |
| 24 | IGLV3-27 | immunoglobulin lambda variable 3-27 [Source:HGNC Symbol;Acc:HGNC:5910] | 11693 | 0.000 | 0.6848 | No |
| 25 | IGLV3-21 | immunoglobulin lambda variable 3-21 [Source:HGNC Symbol;Acc:HGNC:5905] | 11694 | 0.000 | 0.6848 | No |
| 26 | IGLV3-1 | immunoglobulin lambda variable 3-1 [Source:HGNC Symbol;Acc:HGNC:5896] | 12547 | 0.000 | 0.6618 | No |
| 27 | IGKV1-39 | immunoglobulin kappa variable 1-39 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5740] | 12553 | 0.000 | 0.6616 | No |
| 28 | IGKV1-33 | immunoglobulin kappa variable 1-33 [Source:HGNC Symbol;Acc:HGNC:5737] | 12563 | 0.000 | 0.6614 | No |
| 29 | IGKV1-16 | immunoglobulin kappa variable 1-16 [Source:HGNC Symbol;Acc:HGNC:5732] | 12581 | 0.000 | 0.6609 | No |
| 30 | IGKV1-17 | immunoglobulin kappa variable 1-17 [Source:HGNC Symbol;Acc:HGNC:5733] | 12582 | 0.000 | 0.6609 | No |
| 31 | IGKV1-12 | immunoglobulin kappa variable 1-12 [Source:HGNC Symbol;Acc:HGNC:5730] | 12583 | 0.000 | 0.6609 | No |
| 32 | IGKV2D-28 | immunoglobulin kappa variable 2D-28 [Source:HGNC Symbol;Acc:HGNC:5799] | 12705 | 0.000 | 0.6577 | No |
| 33 | IGKV2D-30 | immunoglobulin kappa variable 2D-30 [Source:HGNC Symbol;Acc:HGNC:5801] | 12714 | 0.000 | 0.6574 | No |
| 34 | IGKV2D-40 | immunoglobulin kappa variable 2D-40 [Source:HGNC Symbol;Acc:HGNC:5804] | 12718 | 0.000 | 0.6574 | No |
| 35 | IGKV5-2 | immunoglobulin kappa variable 5-2 [Source:HGNC Symbol;Acc:HGNC:5835] | 13885 | 0.000 | 0.6259 | No |
| 36 | IGLV2-8 | immunoglobulin lambda variable 2-8 [Source:HGNC Symbol;Acc:HGNC:5895] | 14895 | 0.000 | 0.5986 | No |
| 37 | IGLV2-11 | immunoglobulin lambda variable 2-11 [Source:HGNC Symbol;Acc:HGNC:5887] | 16166 | 0.000 | 0.5643 | No |
| 38 | IGLV2-14 | immunoglobulin lambda variable 2-14 [Source:HGNC Symbol;Acc:HGNC:5888] | 16167 | 0.000 | 0.5643 | No |
| 39 | IGLV2-23 | immunoglobulin lambda variable 2-23 [Source:HGNC Symbol;Acc:HGNC:5890] | 16173 | 0.000 | 0.5642 | No |
| 40 | IGHG4 | immunoglobulin heavy constant gamma 4 (G4m marker) [Source:HGNC Symbol;Acc:HGNC:5528] | 17083 | 0.000 | 0.5396 | No |
| 41 | IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) [Source:HGNC Symbol;Acc:HGNC:5525] | 17086 | 0.000 | 0.5396 | No |
| 42 | IGHG2 | immunoglobulin heavy constant gamma 2 (G2m marker) [Source:HGNC Symbol;Acc:HGNC:5526] | 17087 | 0.000 | 0.5396 | No |
| 43 | IGLC3 | immunoglobulin lambda constant 3 (Kern-Oz+ marker) [Source:HGNC Symbol;Acc:HGNC:5857] | 17635 | 0.000 | 0.5248 | No |
| 44 | IGLC2 | immunoglobulin lambda constant 2 [Source:HGNC Symbol;Acc:HGNC:5856] | 17639 | 0.000 | 0.5247 | No |
| 45 | IGHV3-23 | immunoglobulin heavy variable 3-23 [Source:HGNC Symbol;Acc:HGNC:5588] | 17887 | 0.000 | 0.5180 | No |
| 46 | IGHV3-30 | immunoglobulin heavy variable 3-30 [Source:HGNC Symbol;Acc:HGNC:5591] | 17905 | 0.000 | 0.5176 | No |
| 47 | IGHV3-33 | immunoglobulin heavy variable 3-33 [Source:HGNC Symbol;Acc:HGNC:5596] | 17908 | 0.000 | 0.5175 | No |
| 48 | IGHV3-11 | immunoglobulin heavy variable 3-11 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5580] | 17947 | 0.000 | 0.5165 | No |
| 49 | IGHV3-13 | immunoglobulin heavy variable 3-13 [Source:HGNC Symbol;Acc:HGNC:5581] | 17950 | 0.000 | 0.5164 | No |
| 50 | IGHV3-48 | immunoglobulin heavy variable 3-48 [Source:HGNC Symbol;Acc:HGNC:5606] | 18124 | 0.000 | 0.5118 | No |
| 51 | IGHV3-53 | immunoglobulin heavy variable 3-53 [Source:HGNC Symbol;Acc:HGNC:5610] | 18133 | 0.000 | 0.5116 | No |
| 52 | IGKV1-5 | immunoglobulin kappa variable 1-5 [Source:HGNC Symbol;Acc:HGNC:5741] | 18183 | 0.000 | 0.5102 | No |
| 53 | IGKV4-1 | immunoglobulin kappa variable 4-1 [Source:HGNC Symbol;Acc:HGNC:5834] | 19165 | 0.000 | 0.4837 | No |
| 54 | IGKV1D-39 | immunoglobulin kappa variable 1D-39 [Source:HGNC Symbol;Acc:HGNC:5756] | 22598 | 0.000 | 0.3910 | No |
| 55 | IGKV1D-33 | immunoglobulin kappa variable 1D-33 [Source:HGNC Symbol;Acc:HGNC:5753] | 22600 | 0.000 | 0.3910 | No |
| 56 | IGKV1D-16 | immunoglobulin kappa variable 1D-16 [Source:HGNC Symbol;Acc:HGNC:5748] | 22632 | 0.000 | 0.3902 | No |
| 57 | IGKV1D-12 | immunoglobulin kappa variable 1D-12 [Source:HGNC Symbol;Acc:HGNC:5746] | 22639 | 0.000 | 0.3900 | No |
| 58 | CD3G | CD3g molecule [Source:HGNC Symbol;Acc:HGNC:1675] | 22763 | 0.000 | 0.3867 | No |
| 59 | IGLV6-57 | immunoglobulin lambda variable 6-57 [Source:HGNC Symbol;Acc:HGNC:5927] | 22869 | 0.000 | 0.3839 | No |
| 60 | IGKV3D-20 | immunoglobulin kappa variable 3D-20 [Source:HGNC Symbol;Acc:HGNC:5825] | 23577 | 0.000 | 0.3648 | No |
| 61 | IGLV1-40 | immunoglobulin lambda variable 1-40 [Source:HGNC Symbol;Acc:HGNC:5877] | 24281 | 0.000 | 0.3458 | No |
| 62 | IGLV1-47 | immunoglobulin lambda variable 1-47 [Source:HGNC Symbol;Acc:HGNC:5880] | 24282 | 0.000 | 0.3458 | No |
| 63 | IGLV1-44 | immunoglobulin lambda variable 1-44 [Source:HGNC Symbol;Acc:HGNC:5879] | 24283 | 0.000 | 0.3458 | No |
| 64 | IGLV1-51 | immunoglobulin lambda variable 1-51 [Source:HGNC Symbol;Acc:HGNC:5882] | 24296 | 0.000 | 0.3454 | No |
| 65 | IGKV3-15 | immunoglobulin kappa variable 3-15 [Source:HGNC Symbol;Acc:HGNC:5816] | 24804 | 0.000 | 0.3317 | No |
| 66 | IGKV3-11 | immunoglobulin kappa variable 3-11 [Source:HGNC Symbol;Acc:HGNC:5815] | 24810 | 0.000 | 0.3316 | No |
| 67 | IGKV3-20 | immunoglobulin kappa variable 3-20 [Source:HGNC Symbol;Acc:HGNC:5817] | 24835 | 0.000 | 0.3310 | No |
| 68 | IGHV1-2 | immunoglobulin heavy variable 1-2 [Source:HGNC Symbol;Acc:HGNC:5550] | 26520 | 0.000 | 0.2855 | No |
| 69 | IGHV2-5 | immunoglobulin heavy variable 2-5 [Source:HGNC Symbol;Acc:HGNC:5576] | 26925 | 0.000 | 0.2746 | No |
