Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | REACTOME_INTERLEUKIN_10_SIGNALING |
| Enrichment Score (ES) | 0.91807514 |
| Normalized Enrichment Score (NES) | 2.0938413 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 0 | 4.989 | 0.0633 | Yes |
| 2 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 1 | 4.975 | 0.1264 | Yes |
| 3 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 2 | 4.972 | 0.1895 | Yes |
| 4 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 4 | 4.962 | 0.2524 | Yes |
| 5 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 7 | 4.952 | 0.3152 | Yes |
| 6 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 12 | 4.922 | 0.3775 | Yes |
| 7 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 13 | 4.920 | 0.4399 | Yes |
| 8 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 37 | 4.718 | 0.4992 | Yes |
| 9 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 48 | 4.592 | 0.5571 | Yes |
| 10 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 49 | 4.576 | 0.6152 | Yes |
| 11 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 51 | 4.548 | 0.6729 | Yes |
| 12 | PTAFR | platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582] | 264 | 3.168 | 0.7073 | Yes |
| 13 | IL10 | interleukin 10 [Source:HGNC Symbol;Acc:HGNC:5962] | 377 | 2.677 | 0.7383 | Yes |
| 14 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 525 | 2.303 | 0.7635 | Yes |
| 15 | STAT3 | signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364] | 550 | 2.237 | 0.7912 | Yes |
| 16 | TNFRSF1A | TNF receptor superfamily member 1A [Source:HGNC Symbol;Acc:HGNC:11916] | 575 | 2.183 | 0.8183 | Yes |
| 17 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 663 | 2.046 | 0.8419 | Yes |
| 18 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 722 | 1.944 | 0.8650 | Yes |
| 19 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 732 | 1.930 | 0.8892 | Yes |
| 20 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 1425 | 1.226 | 0.8861 | Yes |
| 21 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 1595 | 1.124 | 0.8958 | Yes |
| 22 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 1607 | 1.113 | 0.9096 | Yes |
| 23 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1775 | 1.020 | 0.9181 | Yes |
| 24 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 2862 | 0.618 | 0.8966 | No |
| 25 | TYK2 | tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12440] | 3146 | 0.548 | 0.8959 | No |
| 26 | CCR1 | C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602] | 4244 | 0.312 | 0.8703 | No |
| 27 | IL12B | interleukin 12B [Source:HGNC Symbol;Acc:HGNC:5970] | 4823 | 0.216 | 0.8574 | No |
| 28 | JAK1 | Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190] | 6189 | 0.025 | 0.8209 | No |
| 29 | IL10RA | interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964] | 6317 | 0.007 | 0.8175 | No |
| 30 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6420 | 0.000 | 0.8148 | No |
| 31 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6431 | 0.000 | 0.8145 | No |
| 32 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6434 | 0.000 | 0.8145 | No |
| 33 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 13734 | 0.000 | 0.6174 | No |
| 34 | CCL3L1 | C-C motif chemokine ligand 3 like 1 [Source:HGNC Symbol;Acc:HGNC:10628] | 14669 | 0.000 | 0.5922 | No |
| 35 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14670 | 0.000 | 0.5922 | No |
| 36 | IL1R1 | interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993] | 15868 | 0.000 | 0.5599 | No |
| 37 | IL1R2 | interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994] | 15869 | 0.000 | 0.5599 | No |
| 38 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18143 | 0.000 | 0.4985 | No |
| 39 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19309 | 0.000 | 0.4671 | No |
| 40 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19318 | 0.000 | 0.4669 | No |
| 41 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22684 | 0.000 | 0.3760 | No |
| 42 | CD80 | CD80 molecule [Source:HGNC Symbol;Acc:HGNC:1700] | 22855 | 0.000 | 0.3715 | No |
| 43 | CSF2 | colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434] | 24228 | 0.000 | 0.3344 | No |
| 44 | FCER2 | Fc fragment of IgE receptor II [Source:HGNC Symbol;Acc:HGNC:3612] | 25697 | 0.000 | 0.2948 | No |
| 45 | IL12A | interleukin 12A [Source:HGNC Symbol;Acc:HGNC:5969] | 26600 | 0.000 | 0.2704 | No |
| 46 | IL10RB | interleukin 10 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:5965] | 32949 | -1.001 | 0.1118 | No |
