Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | SANA_TNF_SIGNALING_UP |
| Enrichment Score (ES) | 0.8376216 |
| Normalized Enrichment Score (NES) | 2.0987594 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 8 | 4.948 | 0.0346 | Yes |
| 2 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 24 | 4.813 | 0.0680 | Yes |
| 3 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 31 | 4.755 | 0.1013 | Yes |
| 4 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 35 | 4.721 | 0.1344 | Yes |
| 5 | SLC15A3 | solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068] | 44 | 4.633 | 0.1667 | Yes |
| 6 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 48 | 4.592 | 0.1989 | Yes |
| 7 | IFIH1 | interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873] | 53 | 4.525 | 0.2306 | Yes |
| 8 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 55 | 4.511 | 0.2623 | Yes |
| 9 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 68 | 4.348 | 0.2926 | Yes |
| 10 | PLA1A | phospholipase A1 member A [Source:HGNC Symbol;Acc:HGNC:17661] | 109 | 4.034 | 0.3199 | Yes |
| 11 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 134 | 3.887 | 0.3465 | Yes |
| 12 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 143 | 3.828 | 0.3732 | Yes |
| 13 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 144 | 3.824 | 0.4001 | Yes |
| 14 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 149 | 3.787 | 0.4266 | Yes |
| 15 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 158 | 3.722 | 0.4526 | Yes |
| 16 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 160 | 3.711 | 0.4787 | Yes |
| 17 | SERPINE1 | serpin family E member 1 [Source:HGNC Symbol;Acc:HGNC:8583] | 177 | 3.605 | 0.5036 | Yes |
| 18 | ITGAV | integrin subunit alpha V [Source:HGNC Symbol;Acc:HGNC:6150] | 189 | 3.534 | 0.5281 | Yes |
| 19 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 198 | 3.495 | 0.5525 | Yes |
| 20 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 216 | 3.383 | 0.5758 | Yes |
| 21 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 221 | 3.363 | 0.5993 | Yes |
| 22 | TAPBP | TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566] | 250 | 3.232 | 0.6213 | Yes |
| 23 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 254 | 3.217 | 0.6438 | Yes |
| 24 | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:15925] | 318 | 2.927 | 0.6627 | Yes |
| 25 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 400 | 2.600 | 0.6788 | Yes |
| 26 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 419 | 2.554 | 0.6963 | Yes |
| 27 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 442 | 2.499 | 0.7132 | Yes |
| 28 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 525 | 2.303 | 0.7272 | Yes |
| 29 | DNAJA1 | DnaJ heat shock protein family (Hsp40) member A1 [Source:HGNC Symbol;Acc:HGNC:5229] | 617 | 2.116 | 0.7396 | Yes |
| 30 | CASP1 | caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499] | 759 | 1.884 | 0.7491 | Yes |
| 31 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 766 | 1.873 | 0.7621 | Yes |
| 32 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 850 | 1.724 | 0.7720 | Yes |
| 33 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 949 | 1.612 | 0.7806 | Yes |
| 34 | HLA-E | major histocompatibility complex, class I, E [Source:HGNC Symbol;Acc:HGNC:4962] | 999 | 1.553 | 0.7902 | Yes |
| 35 | LIPG | lipase G, endothelial type [Source:HGNC Symbol;Acc:HGNC:6623] | 1000 | 1.551 | 0.8011 | Yes |
| 36 | HLA-A | major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931] | 1007 | 1.543 | 0.8118 | Yes |
| 37 | RABL3 | RAB, member of RAS oncogene family like 3 [Source:HGNC Symbol;Acc:HGNC:18072] | 1223 | 1.372 | 0.8157 | Yes |
| 38 | HLA-B | major histocompatibility complex, class I, B [Source:HGNC Symbol;Acc:HGNC:4932] | 1230 | 1.368 | 0.8251 | Yes |
| 39 | FTH1 | ferritin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:3976] | 1256 | 1.345 | 0.8339 | Yes |
| 40 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 1674 | 1.068 | 0.8301 | Yes |
| 41 | INHBA | inhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066] | 1676 | 1.067 | 0.8376 | Yes |
| 42 | DENND11 | DENN domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29472] | 2774 | 0.645 | 0.8125 | No |
| 43 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 2862 | 0.618 | 0.8145 | No |
| 44 | SPAG9 | sperm associated antigen 9 [Source:HGNC Symbol;Acc:HGNC:14524] | 3764 | 0.409 | 0.7930 | No |
| 45 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 4193 | 0.325 | 0.7838 | No |
| 46 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 4623 | 0.248 | 0.7739 | No |
| 47 | MMP10 | matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156] | 4847 | 0.214 | 0.7694 | No |
| 48 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 5152 | 0.168 | 0.7624 | No |
| 49 | RAC3 | Rac family small GTPase 3 [Source:HGNC Symbol;Acc:HGNC:9803] | 5726 | 0.093 | 0.7475 | No |
| 50 | MMP3 | matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173] | 5731 | 0.092 | 0.7481 | No |
| 51 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6401 | 0.000 | 0.7300 | No |
| 52 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6434 | 0.000 | 0.7291 | No |
| 53 | PDGFRL | platelet derived growth factor receptor like [Source:HGNC Symbol;Acc:HGNC:8805] | 7528 | 0.000 | 0.6996 | No |
| 54 | APOL1 | apolipoprotein L1 [Source:HGNC Symbol;Acc:HGNC:618] | 10071 | 0.000 | 0.6309 | No |
| 55 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 10073 | 0.000 | 0.6309 | No |
| 56 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10724 | 0.000 | 0.6133 | No |
| 57 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 11064 | 0.000 | 0.6042 | No |
| 58 | ICOSLG | inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087] | 11170 | 0.000 | 0.6013 | No |
| 59 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12458 | 0.000 | 0.5665 | No |
| 60 | IL32 | interleukin 32 [Source:HGNC Symbol;Acc:HGNC:16830] | 13769 | 0.000 | 0.5311 | No |
| 61 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 13825 | 0.000 | 0.5297 | No |
| 62 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18143 | 0.000 | 0.4130 | No |
| 63 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18785 | 0.000 | 0.3957 | No |
| 64 | CTHRC1 | collagen triple helix repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:18831] | 18810 | 0.000 | 0.3950 | No |
| 65 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19304 | 0.000 | 0.3817 | No |
| 66 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19309 | 0.000 | 0.3816 | No |
| 67 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19320 | 0.000 | 0.3813 | No |
| 68 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22675 | 0.000 | 0.2907 | No |
| 69 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22677 | 0.000 | 0.2907 | No |
| 70 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22684 | 0.000 | 0.2905 | No |
| 71 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 23463 | 0.000 | 0.2695 | No |
| 72 | ANO9 | anoctamin 9 [Source:HGNC Symbol;Acc:HGNC:20679] | 24760 | 0.000 | 0.2345 | No |
| 73 | SSPN | sarcospan [Source:HGNC Symbol;Acc:HGNC:11322] | 26731 | 0.000 | 0.1812 | No |
| 74 | HSD17B11 | hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960] | 27683 | -0.079 | 0.1561 | No |
| 75 | C1S | complement C1s [Source:HGNC Symbol;Acc:HGNC:1247] | 29570 | -0.335 | 0.1075 | No |
| 76 | C1QTNF1 | C1q and TNF related 1 [Source:HGNC Symbol;Acc:HGNC:14324] | 30747 | -0.514 | 0.0793 | No |
| 77 | ATP13A3 | ATPase 13A3 [Source:HGNC Symbol;Acc:HGNC:24113] | 31274 | -0.603 | 0.0694 | No |
| 78 | DRAM1 | DNA damage regulated autophagy modulator 1 [Source:HGNC Symbol;Acc:HGNC:25645] | 34391 | -1.497 | -0.0043 | No |
| 79 | RHOB | ras homolog family member B [Source:HGNC Symbol;Acc:HGNC:668] | 34715 | -1.633 | -0.0016 | No |
| 80 | NCEH1 | neutral cholesterol ester hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:29260] | 35003 | -1.769 | 0.0031 | No |
| 81 | BPGM | bisphosphoglycerate mutase [Source:HGNC Symbol;Acc:HGNC:1093] | 35428 | -2.032 | 0.0060 | No |
| 82 | OXR1 | oxidation resistance 1 [Source:HGNC Symbol;Acc:HGNC:15822] | 35521 | -2.095 | 0.0182 | No |
| 83 | SMAD3 | SMAD family member 3 [Source:HGNC Symbol;Acc:HGNC:6769] | 36750 | -3.438 | 0.0092 | No |
