Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | SEKI_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.85779244 |
| Normalized Enrichment Score (NES) | 2.1752186 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 1 | 4.975 | 0.0312 | Yes |
| 2 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 6 | 4.960 | 0.0622 | Yes |
| 3 | GBP4 | guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480] | 14 | 4.909 | 0.0928 | Yes |
| 4 | GBP6 | guanylate binding protein family member 6 [Source:HGNC Symbol;Acc:HGNC:25395] | 19 | 4.873 | 0.1232 | Yes |
| 5 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 26 | 4.802 | 0.1532 | Yes |
| 6 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 27 | 4.798 | 0.1832 | Yes |
| 7 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 30 | 4.761 | 0.2131 | Yes |
| 8 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 43 | 4.635 | 0.2418 | Yes |
| 9 | SLC15A3 | solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068] | 44 | 4.633 | 0.2708 | Yes |
| 10 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 48 | 4.592 | 0.2996 | Yes |
| 11 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 92 | 4.151 | 0.3244 | Yes |
| 12 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 106 | 4.064 | 0.3496 | Yes |
| 13 | RND1 | Rho family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:18314] | 110 | 4.024 | 0.3747 | Yes |
| 14 | ZC3H12A | zinc finger CCCH-type containing 12A [Source:HGNC Symbol;Acc:HGNC:26259] | 120 | 3.966 | 0.3993 | Yes |
| 15 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 128 | 3.919 | 0.4237 | Yes |
| 16 | ZMYND15 | zinc finger MYND-type containing 15 [Source:HGNC Symbol;Acc:HGNC:20997] | 133 | 3.893 | 0.4480 | Yes |
| 17 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 143 | 3.828 | 0.4718 | Yes |
| 18 | PLK2 | polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699] | 147 | 3.806 | 0.4956 | Yes |
| 19 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 157 | 3.739 | 0.5188 | Yes |
| 20 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 158 | 3.722 | 0.5421 | Yes |
| 21 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 170 | 3.641 | 0.5647 | Yes |
| 22 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 202 | 3.471 | 0.5856 | Yes |
| 23 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 216 | 3.383 | 0.6064 | Yes |
| 24 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 221 | 3.363 | 0.6274 | Yes |
| 25 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 232 | 3.304 | 0.6479 | Yes |
| 26 | RAB20 | RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260] | 284 | 3.081 | 0.6658 | Yes |
| 27 | SLC4A7 | solute carrier family 4 member 7 [Source:HGNC Symbol;Acc:HGNC:11033] | 298 | 3.016 | 0.6844 | Yes |
| 28 | SLC11A2 | solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908] | 367 | 2.707 | 0.6995 | Yes |
| 29 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 419 | 2.554 | 0.7141 | Yes |
| 30 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 442 | 2.499 | 0.7292 | Yes |
| 31 | MAFF | MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780] | 459 | 2.451 | 0.7442 | Yes |
| 32 | EXOC3L4 | exocyst complex component 3 like 4 [Source:HGNC Symbol;Acc:HGNC:20120] | 463 | 2.445 | 0.7594 | Yes |
| 33 | JDP2 | Jun dimerization protein 2 [Source:HGNC Symbol;Acc:HGNC:17546] | 485 | 2.387 | 0.7738 | Yes |
| 34 | SH3PXD2B | SH3 and PX domains 2B [Source:HGNC Symbol;Acc:HGNC:29242] | 521 | 2.305 | 0.7873 | Yes |
| 35 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 525 | 2.303 | 0.8017 | Yes |
| 36 | NFKBIE | NFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799] | 580 | 2.171 | 0.8138 | Yes |
| 37 | FAS | Fas cell surface death receptor [Source:HGNC Symbol;Acc:HGNC:11920] | 647 | 2.072 | 0.8250 | Yes |
| 38 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 713 | 1.960 | 0.8356 | Yes |
| 39 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 755 | 1.889 | 0.8463 | Yes |
| 40 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 766 | 1.873 | 0.8578 | Yes |
| 41 | GSAP | gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042] | 1570 | 1.138 | 0.8432 | No |
| 42 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 1595 | 1.124 | 0.8496 | No |
| 43 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 1674 | 1.068 | 0.8542 | No |
| 44 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 1800 | 1.011 | 0.8572 | No |
| 45 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 3097 | 0.559 | 0.8257 | No |
| 46 | CEMIP2 | cell migration inducing hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:11869] | 3152 | 0.546 | 0.8276 | No |
| 47 | NEURL3 | neuralized E3 ubiquitin protein ligase 3 [Source:HGNC Symbol;Acc:HGNC:25162] | 4390 | 0.288 | 0.7960 | No |
| 48 | TCIM | transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] | 5143 | 0.170 | 0.7768 | No |
| 49 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 5362 | 0.139 | 0.7718 | No |
| 50 | SELE | selectin E [Source:HGNC Symbol;Acc:HGNC:10718] | 7171 | 0.000 | 0.7229 | No |
| 51 | PRRX1 | paired related homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9142] | 8580 | 0.000 | 0.6849 | No |
| 52 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8710 | 0.000 | 0.6814 | No |
| 53 | NGFR | nerve growth factor receptor [Source:HGNC Symbol;Acc:HGNC:7809] | 10326 | 0.000 | 0.6378 | No |
| 54 | ICOSLG | inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087] | 11170 | 0.000 | 0.6150 | No |
| 55 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 13825 | 0.000 | 0.5433 | No |
| 56 | LRATD1 | LRAT domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20743] | 17922 | 0.000 | 0.4326 | No |
| 57 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18143 | 0.000 | 0.4267 | No |
| 58 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 18752 | 0.000 | 0.4102 | No |
| 59 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 18865 | 0.000 | 0.4072 | No |
| 60 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19304 | 0.000 | 0.3954 | No |
| 61 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19318 | 0.000 | 0.3950 | No |
| 62 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19320 | 0.000 | 0.3950 | No |
| 63 | ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif 7 [Source:HGNC Symbol;Acc:HGNC:223] | 19889 | 0.000 | 0.3797 | No |
| 64 | TSLP | thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743] | 21883 | 0.000 | 0.3258 | No |
| 65 | EGFR | epidermal growth factor receptor [Source:HGNC Symbol;Acc:HGNC:3236] | 21916 | 0.000 | 0.3249 | No |
| 66 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22677 | 0.000 | 0.3044 | No |
| 67 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22684 | 0.000 | 0.3043 | No |
| 68 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 26426 | 0.000 | 0.2032 | No |
| 69 | BIRC2 | baculoviral IAP repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:590] | 30595 | -0.487 | 0.0936 | No |
| 70 | SCHIP1 | schwannomin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:15678] | 30888 | -0.538 | 0.0891 | No |
| 71 | EGR3 | early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240] | 31757 | -0.699 | 0.0700 | No |
| 72 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 32277 | -0.825 | 0.0612 | No |
| 73 | GPR68 | G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519] | 33868 | -1.293 | 0.0263 | No |
| 74 | ABCB1 | ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] | 34365 | -1.485 | 0.0223 | No |
| 75 | RFX5 | regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:9986] | 34940 | -1.742 | 0.0177 | No |
| 76 | BMP2 | bone morphogenetic protein 2 [Source:HGNC Symbol;Acc:HGNC:1069] | 35197 | -1.888 | 0.0226 | No |
| 77 | TJP2 | tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828] | 35690 | -2.224 | 0.0232 | No |
| 78 | SLCO4A1 | solute carrier organic anion transporter family member 4A1 [Source:HGNC Symbol;Acc:HGNC:10953] | 35807 | -2.321 | 0.0347 | No |
