Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | GGGNNTTTCC_NFKB_Q6_01 |
| Enrichment Score (ES) | 0.5016592 |
| Normalized Enrichment Score (NES) | 1.3309561 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 0 | 4.989 | 0.0324 | Yes |
| 2 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 12 | 4.922 | 0.0641 | Yes |
| 3 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 49 | 4.576 | 0.0929 | Yes |
| 4 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 62 | 4.435 | 0.1214 | Yes |
| 5 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 143 | 3.828 | 0.1441 | Yes |
| 6 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 157 | 3.739 | 0.1681 | Yes |
| 7 | TNFSF15 | TNF superfamily member 15 [Source:HGNC Symbol;Acc:HGNC:11931] | 159 | 3.711 | 0.1922 | Yes |
| 8 | CCND2 | cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583] | 168 | 3.656 | 0.2157 | Yes |
| 9 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 170 | 3.641 | 0.2394 | Yes |
| 10 | BCL3 | BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998] | 174 | 3.625 | 0.2628 | Yes |
| 11 | EHD1 | EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242] | 207 | 3.424 | 0.2842 | Yes |
| 12 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 216 | 3.383 | 0.3060 | Yes |
| 13 | SH2B3 | SH2B adaptor protein 3 [Source:HGNC Symbol;Acc:HGNC:29605] | 480 | 2.394 | 0.3144 | Yes |
| 14 | IPO4 | importin 4 [Source:HGNC Symbol;Acc:HGNC:19426] | 500 | 2.344 | 0.3292 | Yes |
| 15 | CCDC80 | coiled-coil domain containing 80 [Source:HGNC Symbol;Acc:HGNC:30649] | 503 | 2.334 | 0.3443 | Yes |
| 16 | RAP2C | RAP2C, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:21165] | 544 | 2.248 | 0.3578 | Yes |
| 17 | RYBP | RING1 and YY1 binding protein [Source:HGNC Symbol;Acc:HGNC:10480] | 628 | 2.101 | 0.3692 | Yes |
| 18 | FHL3 | four and a half LIM domains 3 [Source:HGNC Symbol;Acc:HGNC:3704] | 670 | 2.033 | 0.3813 | Yes |
| 19 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 732 | 1.930 | 0.3922 | Yes |
| 20 | IER5 | immediate early response 5 [Source:HGNC Symbol;Acc:HGNC:5393] | 838 | 1.741 | 0.4007 | Yes |
| 21 | LASP1 | LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513] | 1028 | 1.520 | 0.4055 | Yes |
| 22 | ORAI1 | ORAI calcium release-activated calcium modulator 1 [Source:HGNC Symbol;Acc:HGNC:25896] | 1053 | 1.503 | 0.4146 | Yes |
| 23 | PFN1 | profilin 1 [Source:HGNC Symbol;Acc:HGNC:8881] | 1071 | 1.494 | 0.4238 | Yes |
| 24 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 1226 | 1.371 | 0.4286 | Yes |
| 25 | ZFAND3 | zinc finger AN1-type containing 3 [Source:HGNC Symbol;Acc:HGNC:18019] | 1283 | 1.327 | 0.4357 | Yes |
| 26 | CPEB4 | cytoplasmic polyadenylation element binding protein 4 [Source:HGNC Symbol;Acc:HGNC:21747] | 1288 | 1.321 | 0.4442 | Yes |
| 27 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 1384 | 1.254 | 0.4498 | Yes |
| 28 | TPM3 | tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012] | 1544 | 1.154 | 0.4530 | Yes |
| 29 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 1607 | 1.113 | 0.4585 | Yes |
| 30 | SLAMF8 | SLAM family member 8 [Source:HGNC Symbol;Acc:HGNC:21391] | 1617 | 1.106 | 0.4655 | Yes |
| 31 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 1674 | 1.068 | 0.4709 | Yes |
| 32 | MT2A | metallothionein 2A [Source:HGNC Symbol;Acc:HGNC:7406] | 1689 | 1.060 | 0.4774 | Yes |
| 33 | KY | kyphoscoliosis peptidase [Source:HGNC Symbol;Acc:HGNC:26576] | 1871 | 0.978 | 0.4789 | Yes |
| 34 | E2F3 | E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115] | 1924 | 0.946 | 0.4836 | Yes |
| 35 | MAML2 | mastermind like transcriptional coactivator 2 [Source:HGNC Symbol;Acc:HGNC:16259] | 2015 | 0.913 | 0.4871 | Yes |
| 36 | CXCR5 | C-X-C motif chemokine receptor 5 [Source:HGNC Symbol;Acc:HGNC:1060] | 2085 | 0.884 | 0.4910 | Yes |
| 37 | RELB | RELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956] | 2200 | 0.838 | 0.4933 | Yes |
| 38 | CNIH2 | cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744] | 2229 | 0.825 | 0.4979 | Yes |
| 39 | UBE2M | ubiquitin conjugating enzyme E2 M [Source:HGNC Symbol;Acc:HGNC:12491] | 2286 | 0.806 | 0.5017 | Yes |
| 40 | BATF | basic leucine zipper ATF-like transcription factor [Source:HGNC Symbol;Acc:HGNC:958] | 2940 | 0.594 | 0.4878 | No |
| 41 | RBMS1 | RNA binding motif single stranded interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9907] | 2955 | 0.590 | 0.4913 | No |
| 42 | ETV1 | ETS variant transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3490] | 3066 | 0.565 | 0.4920 | No |
| 43 | STAT6 | signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368] | 3302 | 0.507 | 0.4889 | No |
| 44 | WNT10A | Wnt family member 10A [Source:HGNC Symbol;Acc:HGNC:13829] | 3758 | 0.410 | 0.4793 | No |
| 45 | UPF2 | UPF2 regulator of nonsense mediated mRNA decay [Source:HGNC Symbol;Acc:HGNC:17854] | 3862 | 0.389 | 0.4790 | No |
| 46 | N4BP1 | NEDD4 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29850] | 3880 | 0.383 | 0.4811 | No |
| 47 | TFEC | transcription factor EC [Source:HGNC Symbol;Acc:HGNC:11754] | 3905 | 0.378 | 0.4829 | No |
| 48 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 4409 | 0.286 | 0.4711 | No |
| 49 | RSPRY1 | ring finger and SPRY domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29420] | 4763 | 0.225 | 0.4630 | No |
| 50 | HIVEP1 | HIVEP zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:4920] | 5084 | 0.180 | 0.4555 | No |
| 51 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 5152 | 0.168 | 0.4548 | No |
| 52 | C1QL1 | complement C1q like 1 [Source:HGNC Symbol;Acc:HGNC:24182] | 5324 | 0.144 | 0.4511 | No |
| 53 | CSF2RB | colony stimulating factor 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:2436] | 5628 | 0.106 | 0.4436 | No |
| 54 | CNTF | ciliary neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:2169] | 5681 | 0.098 | 0.4429 | No |
| 55 | ENTHD1 | ENTH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26352] | 5886 | 0.070 | 0.4378 | No |
| 56 | SLC25A18 | solute carrier family 25 member 18 [Source:HGNC Symbol;Acc:HGNC:10988] | 6231 | 0.018 | 0.4286 | No |
| 57 | GREM1 | gremlin 1, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:2001] | 8215 | 0.000 | 0.3750 | No |
| 58 | POU2F3 | POU class 2 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:19864] | 8402 | 0.000 | 0.3699 | No |
| 59 | PRR34 | PRR34 long non-coding RNA [Source:HGNC Symbol;Acc:HGNC:25606] | 8816 | 0.000 | 0.3587 | No |
| 60 | MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:6765] | 9070 | 0.000 | 0.3519 | No |
| 61 | TNFRSF9 | TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924] | 9802 | 0.000 | 0.3321 | No |
| 62 | KCNS3 | potassium voltage-gated channel modifier subfamily S member 3 [Source:HGNC Symbol;Acc:HGNC:6302] | 9911 | 0.000 | 0.3292 | No |
| 63 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 10312 | 0.000 | 0.3184 | No |
| 64 | IL1RAPL1 | interleukin 1 receptor accessory protein like 1 [Source:HGNC Symbol;Acc:HGNC:5996] | 10398 | 0.000 | 0.3161 | No |
| 65 | NRIP2 | nuclear receptor interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:23078] | 10806 | 0.000 | 0.3051 | No |
| 66 | NTRK3 | neurotrophic receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:8033] | 10923 | 0.000 | 0.3019 | No |
| 67 | MSX1 | msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391] | 12493 | 0.000 | 0.2595 | No |
| 68 | TLX1 | T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5056] | 14258 | 0.000 | 0.2117 | No |
| 69 | PCSK2 | proprotein convertase subtilisin/kexin type 2 [Source:HGNC Symbol;Acc:HGNC:8744] | 16218 | 0.000 | 0.1587 | No |
| 70 | IL2 | interleukin 2 [Source:HGNC Symbol;Acc:HGNC:6001] | 17623 | 0.000 | 0.1207 | No |
| 71 | LPO | lactoperoxidase [Source:HGNC Symbol;Acc:HGNC:6678] | 18558 | 0.000 | 0.0955 | No |
| 72 | MSC | musculin [Source:HGNC Symbol;Acc:HGNC:7321] | 18917 | 0.000 | 0.0858 | No |
| 73 | BNC2 | basonuclin 2 [Source:HGNC Symbol;Acc:HGNC:30988] | 19130 | 0.000 | 0.0800 | No |
| 74 | NR2F2 | nuclear receptor subfamily 2 group F member 2 [Source:HGNC Symbol;Acc:HGNC:7976] | 19421 | 0.000 | 0.0722 | No |
| 75 | ZNF532 | zinc finger protein 532 [Source:HGNC Symbol;Acc:HGNC:30940] | 21607 | 0.000 | 0.0131 | No |
| 76 | CD70 | CD70 molecule [Source:HGNC Symbol;Acc:HGNC:11937] | 22833 | 0.000 | -0.0201 | No |
| 77 | FOXS1 | forkhead box S1 [Source:HGNC Symbol;Acc:HGNC:3735] | 23168 | 0.000 | -0.0291 | No |
| 78 | LAMA1 | laminin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6481] | 23455 | 0.000 | -0.0369 | No |
| 79 | NRGN | neurogranin [Source:HGNC Symbol;Acc:HGNC:8000] | 23876 | 0.000 | -0.0482 | No |
| 80 | FTHL17 | ferritin heavy chain like 17 [Source:HGNC Symbol;Acc:HGNC:3987] | 24126 | 0.000 | -0.0550 | No |
| 81 | FGF1 | fibroblast growth factor 1 [Source:HGNC Symbol;Acc:HGNC:3665] | 25050 | 0.000 | -0.0799 | No |
| 82 | SOX5 | SRY-box transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:11201] | 25785 | 0.000 | -0.0998 | No |
| 83 | PPP2R5E | protein phosphatase 2 regulatory subunit B'epsilon [Source:HGNC Symbol;Acc:HGNC:9313] | 27121 | -0.003 | -0.1359 | No |
| 84 | GPR182 | G protein-coupled receptor 182 [Source:HGNC Symbol;Acc:HGNC:13708] | 27595 | -0.069 | -0.1482 | No |
| 85 | TP53 | tumor protein p53 [Source:HGNC Symbol;Acc:HGNC:11998] | 27705 | -0.083 | -0.1506 | No |
| 86 | SMPD3 | sphingomyelin phosphodiesterase 3 [Source:HGNC Symbol;Acc:HGNC:14240] | 27828 | -0.099 | -0.1533 | No |
| 87 | TNKS1BP1 | tankyrase 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19081] | 27994 | -0.122 | -0.1570 | No |
| 88 | DCLK1 | doublecortin like kinase 1 [Source:HGNC Symbol;Acc:HGNC:2700] | 28117 | -0.135 | -0.1594 | No |
| 89 | GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28804] | 28140 | -0.138 | -0.1591 | No |
| 90 | BMP2K | BMP2 inducible kinase [Source:HGNC Symbol;Acc:HGNC:18041] | 28329 | -0.161 | -0.1631 | No |
| 91 | SP6 | Sp6 transcription factor [Source:HGNC Symbol;Acc:HGNC:14530] | 28481 | -0.183 | -0.1660 | No |
| 92 | PSME3IP1 | proteasome activator subunit 3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29856] | 28859 | -0.236 | -0.1747 | No |
| 93 | CCR10 | C-C motif chemokine receptor 10 [Source:HGNC Symbol;Acc:HGNC:4474] | 28960 | -0.248 | -0.1758 | No |
| 94 | PLXNB1 | plexin B1 [Source:HGNC Symbol;Acc:HGNC:9103] | 29043 | -0.259 | -0.1763 | No |
| 95 | LTB | lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711] | 29053 | -0.261 | -0.1749 | No |
| 96 | WRAP53 | WD repeat containing antisense to TP53 [Source:HGNC Symbol;Acc:HGNC:25522] | 29138 | -0.273 | -0.1754 | No |
| 97 | CREB1 | cAMP responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2345] | 29540 | -0.330 | -0.1841 | No |
| 98 | CDC27 | cell division cycle 27 [Source:HGNC Symbol;Acc:HGNC:1728] | 29692 | -0.353 | -0.1859 | No |
| 99 | UBE2H | ubiquitin conjugating enzyme E2 H [Source:HGNC Symbol;Acc:HGNC:12484] | 30208 | -0.430 | -0.1970 | No |
| 100 | G3BP1 | G3BP stress granule assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30292] | 31529 | -0.653 | -0.2285 | No |
| 101 | ARID1A | AT-rich interaction domain 1A [Source:HGNC Symbol;Acc:HGNC:11110] | 31620 | -0.674 | -0.2265 | No |
| 102 | FUT7 | fucosyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4018] | 31742 | -0.695 | -0.2253 | No |
| 103 | TCEA2 | transcription elongation factor A2 [Source:HGNC Symbol;Acc:HGNC:11614] | 31789 | -0.713 | -0.2219 | No |
| 104 | SH3KBP1 | SH3 domain containing kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:13867] | 32054 | -0.774 | -0.2240 | No |
| 105 | NFAT5 | nuclear factor of activated T cells 5 [Source:HGNC Symbol;Acc:HGNC:7774] | 32418 | -0.862 | -0.2282 | No |
| 106 | RPS6KA4 | ribosomal protein S6 kinase A4 [Source:HGNC Symbol;Acc:HGNC:10433] | 32596 | -0.904 | -0.2272 | No |
| 107 | PKN1 | protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405] | 32637 | -0.913 | -0.2223 | No |
| 108 | ENO3 | enolase 3 [Source:HGNC Symbol;Acc:HGNC:3354] | 32675 | -0.924 | -0.2173 | No |
| 109 | GEM | GTP binding protein overexpressed in skeletal muscle [Source:HGNC Symbol;Acc:HGNC:4234] | 33564 | -1.191 | -0.2336 | No |
| 110 | SLC12A2 | solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911] | 33668 | -1.225 | -0.2284 | No |
| 111 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 33680 | -1.230 | -0.2207 | No |
| 112 | STX4 | syntaxin 4 [Source:HGNC Symbol;Acc:HGNC:11439] | 33805 | -1.270 | -0.2158 | No |
| 113 | HOXA4 | homeobox A4 [Source:HGNC Symbol;Acc:HGNC:5105] | 34048 | -1.358 | -0.2135 | No |
| 114 | KAT7 | lysine acetyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:17016] | 34130 | -1.386 | -0.2067 | No |
| 115 | CYLD | CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584] | 34240 | -1.428 | -0.2004 | No |
| 116 | CHD6 | chromodomain helicase DNA binding protein 6 [Source:HGNC Symbol;Acc:HGNC:19057] | 34402 | -1.501 | -0.1950 | No |
| 117 | JAK3 | Janus kinase 3 [Source:HGNC Symbol;Acc:HGNC:6193] | 34408 | -1.504 | -0.1853 | No |
| 118 | CCDC107 | coiled-coil domain containing 107 [Source:HGNC Symbol;Acc:HGNC:28465] | 34596 | -1.581 | -0.1801 | No |
| 119 | SLC44A1 | solute carrier family 44 member 1 [Source:HGNC Symbol;Acc:HGNC:18798] | 34916 | -1.729 | -0.1775 | No |
| 120 | CNTNAP1 | contactin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:8011] | 34997 | -1.767 | -0.1682 | No |
| 121 | PNKD | PNKD metallo-beta-lactamase domain containing [Source:HGNC Symbol;Acc:HGNC:9153] | 35315 | -1.956 | -0.1641 | No |
| 122 | SLC6A12 | solute carrier family 6 member 12 [Source:HGNC Symbol;Acc:HGNC:11045] | 35325 | -1.963 | -0.1515 | No |
| 123 | ALG6 | ALG6 alpha-1,3-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:23157] | 35336 | -1.971 | -0.1390 | No |
| 124 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 35345 | -1.974 | -0.1264 | No |
| 125 | ENKD1 | enkurin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25246] | 35357 | -1.984 | -0.1138 | No |
| 126 | RASSF2 | Ras association domain family member 2 [Source:HGNC Symbol;Acc:HGNC:9883] | 35463 | -2.058 | -0.1033 | No |
| 127 | TOM1L1 | target of myb1 like 1 membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:11983] | 35697 | -2.232 | -0.0951 | No |
| 128 | TRIM47 | tripartite motif containing 47 [Source:HGNC Symbol;Acc:HGNC:19020] | 35744 | -2.274 | -0.0815 | No |
| 129 | S1PR2 | sphingosine-1-phosphate receptor 2 [Source:HGNC Symbol;Acc:HGNC:3169] | 36023 | -2.517 | -0.0727 | No |
| 130 | LIX1L | limb and CNS expressed 1 like [Source:HGNC Symbol;Acc:HGNC:28715] | 36056 | -2.549 | -0.0570 | No |
| 131 | MIDEAS | mitotic deacetylase associated SANT domain protein [Source:HGNC Symbol;Acc:HGNC:19853] | 36190 | -2.711 | -0.0429 | No |
| 132 | CALCOCO1 | calcium binding and coiled-coil domain 1 [Source:HGNC Symbol;Acc:HGNC:29306] | 36507 | -3.033 | -0.0318 | No |
| 133 | FAM117A | family with sequence similarity 117 member A [Source:HGNC Symbol;Acc:HGNC:24179] | 36841 | -3.621 | -0.0173 | No |
| 134 | CSF1R | colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433] | 36874 | -3.688 | 0.0058 | No |
