Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_CCNA2 |
| Enrichment Score (ES) | -0.8764432 |
| Normalized Enrichment Score (NES) | -1.7355231 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1902 | 0.962 | -0.0459 | No |
| 2 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25804 | 0.000 | -0.6915 | No |
| 3 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29215 | -0.283 | -0.7820 | No |
| 4 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 31017 | -0.559 | -0.8274 | No |
| 5 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 31272 | -0.602 | -0.8308 | No |
| 6 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 32718 | -0.936 | -0.8645 | No |
| 7 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32856 | -0.976 | -0.8627 | No |
| 8 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33245 | -1.087 | -0.8669 | No |
| 9 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33258 | -1.093 | -0.8610 | No |
| 10 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33793 | -1.266 | -0.8682 | Yes |
| 11 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 33884 | -1.299 | -0.8633 | Yes |
| 12 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33887 | -1.300 | -0.8559 | Yes |
| 13 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 34079 | -1.367 | -0.8533 | Yes |
| 14 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34938 | -1.741 | -0.8665 | Yes |
| 15 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35043 | -1.792 | -0.8591 | Yes |
| 16 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 35148 | -1.850 | -0.8514 | Yes |
| 17 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35386 | -2.005 | -0.8463 | Yes |
| 18 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35573 | -2.135 | -0.8392 | Yes |
| 19 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35717 | -2.250 | -0.8302 | Yes |
| 20 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35799 | -2.315 | -0.8192 | Yes |
| 21 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35816 | -2.333 | -0.8063 | Yes |
| 22 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35837 | -2.347 | -0.7935 | Yes |
| 23 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35861 | -2.370 | -0.7806 | Yes |
| 24 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35874 | -2.384 | -0.7673 | Yes |
| 25 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35901 | -2.411 | -0.7543 | Yes |
| 26 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36000 | -2.501 | -0.7427 | Yes |
| 27 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36076 | -2.578 | -0.7300 | Yes |
| 28 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 36079 | -2.583 | -0.7153 | Yes |
| 29 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 36174 | -2.692 | -0.7025 | Yes |
| 30 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36206 | -2.726 | -0.6878 | Yes |
| 31 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 36227 | -2.746 | -0.6727 | Yes |
| 32 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 36266 | -2.780 | -0.6579 | Yes |
| 33 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36279 | -2.795 | -0.6422 | Yes |
| 34 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36304 | -2.820 | -0.6268 | Yes |
| 35 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36339 | -2.870 | -0.6114 | Yes |
| 36 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36344 | -2.872 | -0.5951 | Yes |
| 37 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36376 | -2.899 | -0.5794 | Yes |
| 38 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36383 | -2.908 | -0.5630 | Yes |
| 39 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36425 | -2.957 | -0.5472 | Yes |
| 40 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 36430 | -2.964 | -0.5304 | Yes |
| 41 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36469 | -2.992 | -0.5144 | Yes |
| 42 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36483 | -3.006 | -0.4976 | Yes |
| 43 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36494 | -3.018 | -0.4807 | Yes |
| 44 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 36516 | -3.057 | -0.4638 | Yes |
| 45 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36535 | -3.075 | -0.4468 | Yes |
| 46 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36586 | -3.138 | -0.4302 | Yes |
| 47 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36591 | -3.140 | -0.4124 | Yes |
| 48 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36592 | -3.140 | -0.3945 | Yes |
| 49 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36607 | -3.171 | -0.3768 | Yes |
| 50 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36611 | -3.176 | -0.3588 | Yes |
| 51 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36622 | -3.191 | -0.3409 | Yes |
| 52 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36630 | -3.207 | -0.3228 | Yes |
| 53 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 36650 | -3.229 | -0.3049 | Yes |
| 54 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36663 | -3.250 | -0.2867 | Yes |
| 55 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36667 | -3.270 | -0.2681 | Yes |
| 56 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36709 | -3.356 | -0.2501 | Yes |
| 57 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36811 | -3.559 | -0.2325 | Yes |
| 58 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36833 | -3.603 | -0.2125 | Yes |
| 59 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36863 | -3.662 | -0.1924 | Yes |
| 60 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36870 | -3.679 | -0.1716 | Yes |
| 61 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36876 | -3.698 | -0.1506 | Yes |
| 62 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36882 | -3.715 | -0.1296 | Yes |
| 63 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36891 | -3.747 | -0.1085 | Yes |
| 64 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36894 | -3.758 | -0.0871 | Yes |
| 65 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36922 | -3.842 | -0.0659 | Yes |
| 66 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36931 | -3.886 | -0.0440 | Yes |
| 67 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36955 | -3.967 | -0.0220 | Yes |
| 68 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 37059 | -4.485 | 0.0008 | Yes |
