Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_CENPE |
| Enrichment Score (ES) | -0.8952903 |
| Normalized Enrichment Score (NES) | -1.672334 |
| Nominal p-value | 0.0 |
| FDR q-value | 6.540697E-5 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1902 | 0.962 | -0.0428 | No |
| 2 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25804 | 0.000 | -0.6879 | No |
| 3 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 31017 | -0.559 | -0.8236 | No |
| 4 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32856 | -0.976 | -0.8645 | No |
| 5 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33245 | -1.087 | -0.8653 | No |
| 6 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33258 | -1.093 | -0.8559 | No |
| 7 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33887 | -1.300 | -0.8613 | No |
| 8 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 35148 | -1.850 | -0.8788 | Yes |
| 9 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 35201 | -1.889 | -0.8634 | Yes |
| 10 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35717 | -2.250 | -0.8573 | Yes |
| 11 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35816 | -2.333 | -0.8392 | Yes |
| 12 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35901 | -2.411 | -0.8200 | Yes |
| 13 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 36174 | -2.692 | -0.8034 | Yes |
| 14 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36206 | -2.726 | -0.7800 | Yes |
| 15 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 36266 | -2.780 | -0.7568 | Yes |
| 16 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36279 | -2.795 | -0.7323 | Yes |
| 17 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36304 | -2.820 | -0.7078 | Yes |
| 18 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36344 | -2.872 | -0.6833 | Yes |
| 19 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36383 | -2.908 | -0.6585 | Yes |
| 20 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36425 | -2.957 | -0.6333 | Yes |
| 21 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 36430 | -2.964 | -0.6070 | Yes |
| 22 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36469 | -2.992 | -0.5814 | Yes |
| 23 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36535 | -3.075 | -0.5558 | Yes |
| 24 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36592 | -3.140 | -0.5294 | Yes |
| 25 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36607 | -3.171 | -0.5015 | Yes |
| 26 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36611 | -3.176 | -0.4734 | Yes |
| 27 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36622 | -3.191 | -0.4452 | Yes |
| 28 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36630 | -3.207 | -0.4169 | Yes |
| 29 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36663 | -3.250 | -0.3888 | Yes |
| 30 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36709 | -3.356 | -0.3602 | Yes |
| 31 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36724 | -3.390 | -0.3304 | Yes |
| 32 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36833 | -3.603 | -0.3013 | Yes |
| 33 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 36862 | -3.659 | -0.2695 | Yes |
| 34 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36870 | -3.679 | -0.2369 | Yes |
| 35 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36876 | -3.698 | -0.2041 | Yes |
| 36 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36882 | -3.715 | -0.1712 | Yes |
| 37 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36891 | -3.747 | -0.1381 | Yes |
| 38 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36917 | -3.817 | -0.1048 | Yes |
| 39 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36922 | -3.842 | -0.0707 | Yes |
| 40 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36955 | -3.967 | -0.0363 | Yes |
| 41 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 37059 | -4.485 | 0.0008 | Yes |
