Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_PCNA |
| Enrichment Score (ES) | -0.86696005 |
| Normalized Enrichment Score (NES) | -1.7306316 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1902 | 0.962 | -0.0457 | No |
| 2 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 2301 | 0.799 | -0.0518 | No |
| 3 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 2534 | 0.725 | -0.0538 | No |
| 4 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25804 | 0.000 | -0.6823 | No |
| 5 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 31017 | -0.559 | -0.8198 | No |
| 6 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 32355 | -0.847 | -0.8509 | No |
| 7 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 32416 | -0.862 | -0.8475 | No |
| 8 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 32718 | -0.936 | -0.8501 | No |
| 9 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32856 | -0.976 | -0.8481 | No |
| 10 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33245 | -1.087 | -0.8522 | No |
| 11 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33793 | -1.266 | -0.8595 | Yes |
| 12 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 33884 | -1.299 | -0.8543 | Yes |
| 13 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33887 | -1.300 | -0.8468 | Yes |
| 14 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 34079 | -1.367 | -0.8439 | Yes |
| 15 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 34151 | -1.393 | -0.8376 | Yes |
| 16 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34588 | -1.576 | -0.8401 | Yes |
| 17 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34938 | -1.741 | -0.8393 | Yes |
| 18 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35043 | -1.792 | -0.8316 | Yes |
| 19 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 35201 | -1.889 | -0.8248 | Yes |
| 20 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35386 | -2.005 | -0.8180 | Yes |
| 21 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35573 | -2.135 | -0.8105 | Yes |
| 22 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35614 | -2.167 | -0.7988 | Yes |
| 23 | PAXIP1 | PAX interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:8624] | 35617 | -2.168 | -0.7861 | Yes |
| 24 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35717 | -2.250 | -0.7756 | Yes |
| 25 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35799 | -2.315 | -0.7642 | Yes |
| 26 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35816 | -2.333 | -0.7509 | Yes |
| 27 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35837 | -2.347 | -0.7377 | Yes |
| 28 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35861 | -2.370 | -0.7244 | Yes |
| 29 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35874 | -2.384 | -0.7107 | Yes |
| 30 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35901 | -2.411 | -0.6973 | Yes |
| 31 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36000 | -2.501 | -0.6852 | Yes |
| 32 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36076 | -2.578 | -0.6721 | Yes |
| 33 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36099 | -2.607 | -0.6574 | Yes |
| 34 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 36164 | -2.684 | -0.6433 | Yes |
| 35 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 36174 | -2.692 | -0.6278 | Yes |
| 36 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36206 | -2.726 | -0.6126 | Yes |
| 37 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 36266 | -2.780 | -0.5979 | Yes |
| 38 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36304 | -2.820 | -0.5823 | Yes |
| 39 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36339 | -2.870 | -0.5664 | Yes |
| 40 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36344 | -2.872 | -0.5496 | Yes |
| 41 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36358 | -2.884 | -0.5330 | Yes |
| 42 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36383 | -2.908 | -0.5166 | Yes |
| 43 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36425 | -2.957 | -0.5004 | Yes |
| 44 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 36430 | -2.964 | -0.4831 | Yes |
| 45 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36469 | -2.992 | -0.4665 | Yes |
| 46 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36586 | -3.138 | -0.4512 | Yes |
| 47 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36592 | -3.140 | -0.4329 | Yes |
| 48 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36607 | -3.171 | -0.4147 | Yes |
| 49 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36611 | -3.176 | -0.3961 | Yes |
| 50 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36622 | -3.191 | -0.3776 | Yes |
| 51 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36630 | -3.207 | -0.3590 | Yes |
| 52 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36663 | -3.250 | -0.3408 | Yes |
| 53 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36667 | -3.270 | -0.3216 | Yes |
| 54 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36674 | -3.282 | -0.3025 | Yes |
| 55 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36709 | -3.356 | -0.2837 | Yes |
| 56 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36811 | -3.559 | -0.2656 | Yes |
| 57 | KIF15 | kinesin family member 15 [Source:HGNC Symbol;Acc:HGNC:17273] | 36837 | -3.615 | -0.2450 | Yes |
| 58 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36870 | -3.679 | -0.2243 | Yes |
| 59 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36876 | -3.698 | -0.2027 | Yes |
| 60 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36882 | -3.715 | -0.1810 | Yes |
| 61 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36891 | -3.747 | -0.1592 | Yes |
| 62 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36894 | -3.758 | -0.1372 | Yes |
| 63 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36917 | -3.817 | -0.1154 | Yes |
| 64 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36922 | -3.842 | -0.0929 | Yes |
| 65 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36931 | -3.886 | -0.0703 | Yes |
| 66 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36955 | -3.967 | -0.0477 | Yes |
| 67 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 37018 | -4.241 | -0.0244 | Yes |
| 68 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 37059 | -4.485 | 0.0008 | Yes |
