Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_RRM1 |
| Enrichment Score (ES) | -0.80954087 |
| Normalized Enrichment Score (NES) | -1.65332 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.7015051E-4 |
| FWER p-Value | 0.005 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCT6A | chaperonin containing TCP1 subunit 6A [Source:HGNC Symbol;Acc:HGNC:1620] | 1807 | 1.008 | -0.0433 | No |
| 2 | PSMD14 | proteasome 26S subunit, non-ATPase 14 [Source:HGNC Symbol;Acc:HGNC:16889] | 1852 | 0.987 | -0.0390 | No |
| 3 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1902 | 0.962 | -0.0350 | No |
| 4 | PTGES3 | prostaglandin E synthase 3 [Source:HGNC Symbol;Acc:HGNC:16049] | 2061 | 0.891 | -0.0344 | No |
| 5 | EIF2S1 | eukaryotic translation initiation factor 2 subunit alpha [Source:HGNC Symbol;Acc:HGNC:3265] | 2120 | 0.869 | -0.0312 | No |
| 6 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 2301 | 0.799 | -0.0316 | No |
| 7 | MRPL35 | mitochondrial ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:14489] | 2396 | 0.767 | -0.0299 | No |
| 8 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 2534 | 0.725 | -0.0296 | No |
| 9 | USP14 | ubiquitin specific peptidase 14 [Source:HGNC Symbol;Acc:HGNC:12612] | 2637 | 0.686 | -0.0286 | No |
| 10 | RAN | RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846] | 5528 | 0.118 | -0.1061 | No |
| 11 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 6236 | 0.018 | -0.1251 | No |
| 12 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25804 | 0.000 | -0.6539 | No |
| 13 | SNRPG | small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163] | 27321 | -0.038 | -0.6946 | No |
| 14 | NUP37 | nucleoporin 37 [Source:HGNC Symbol;Acc:HGNC:29929] | 27941 | -0.114 | -0.7107 | No |
| 15 | METAP2 | methionyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:16672] | 28096 | -0.133 | -0.7142 | No |
| 16 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 28469 | -0.181 | -0.7232 | No |
| 17 | TCP1 | t-complex 1 [Source:HGNC Symbol;Acc:HGNC:11655] | 28874 | -0.238 | -0.7328 | No |
| 18 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 31017 | -0.559 | -0.7876 | No |
| 19 | SERBP1 | SERPINE1 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17860] | 31084 | -0.571 | -0.7862 | No |
| 20 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 31243 | -0.597 | -0.7872 | No |
| 21 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 31808 | -0.715 | -0.7985 | No |
| 22 | SSRP1 | structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327] | 32217 | -0.812 | -0.8051 | Yes |
| 23 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 32355 | -0.847 | -0.8041 | Yes |
| 24 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 32416 | -0.862 | -0.8010 | Yes |
| 25 | CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21906] | 32639 | -0.914 | -0.8019 | Yes |
| 26 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 32718 | -0.936 | -0.7989 | Yes |
| 27 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 32784 | -0.959 | -0.7953 | Yes |
| 28 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32856 | -0.976 | -0.7919 | Yes |
| 29 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33245 | -1.087 | -0.7963 | Yes |
| 30 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33258 | -1.093 | -0.7906 | Yes |
| 31 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 33648 | -1.220 | -0.7944 | Yes |
| 32 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33793 | -1.266 | -0.7913 | Yes |
| 33 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 33884 | -1.299 | -0.7866 | Yes |
| 34 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33887 | -1.300 | -0.7795 | Yes |
| 35 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 34079 | -1.367 | -0.7771 | Yes |
| 36 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 34101 | -1.375 | -0.7701 | Yes |
| 37 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34588 | -1.576 | -0.7745 | Yes |
| 38 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34938 | -1.741 | -0.7744 | Yes |
| 39 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35043 | -1.792 | -0.7673 | Yes |
| 40 | FH | fumarate hydratase [Source:HGNC Symbol;Acc:HGNC:3700] | 35319 | -1.959 | -0.7639 | Yes |
| 41 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35386 | -2.005 | -0.7546 | Yes |
| 42 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35573 | -2.135 | -0.7479 | Yes |
| 43 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35579 | -2.138 | -0.7362 | Yes |
| 44 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35614 | -2.167 | -0.7252 | Yes |
| 45 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35717 | -2.250 | -0.7155 | Yes |
| 46 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35799 | -2.315 | -0.7050 | Yes |
| 47 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35816 | -2.333 | -0.6925 | Yes |
| 48 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35861 | -2.370 | -0.6806 | Yes |
| 49 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35874 | -2.384 | -0.6678 | Yes |
| 50 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35901 | -2.411 | -0.6552 | Yes |
| 51 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36000 | -2.501 | -0.6441 | Yes |
| 52 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36076 | -2.578 | -0.6319 | Yes |
| 53 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 36164 | -2.684 | -0.6194 | Yes |
| 54 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 36174 | -2.692 | -0.6048 | Yes |
| 55 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36206 | -2.726 | -0.5906 | Yes |
| 56 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 36266 | -2.780 | -0.5769 | Yes |
| 57 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36279 | -2.795 | -0.5618 | Yes |
| 58 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36304 | -2.820 | -0.5469 | Yes |
| 59 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36339 | -2.870 | -0.5319 | Yes |
| 60 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36383 | -2.908 | -0.5171 | Yes |
| 61 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36425 | -2.957 | -0.5019 | Yes |
| 62 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 36430 | -2.964 | -0.4856 | Yes |
| 63 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36469 | -2.992 | -0.4701 | Yes |
| 64 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36494 | -3.018 | -0.4541 | Yes |
| 65 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 36556 | -3.101 | -0.4387 | Yes |
| 66 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36586 | -3.138 | -0.4222 | Yes |
| 67 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36592 | -3.140 | -0.4050 | Yes |
| 68 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36607 | -3.171 | -0.3879 | Yes |
| 69 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36611 | -3.176 | -0.3704 | Yes |
| 70 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36622 | -3.191 | -0.3531 | Yes |
| 71 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36630 | -3.207 | -0.3356 | Yes |
| 72 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36663 | -3.250 | -0.3185 | Yes |
| 73 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36667 | -3.270 | -0.3006 | Yes |
| 74 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36674 | -3.282 | -0.2826 | Yes |
| 75 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36709 | -3.356 | -0.2650 | Yes |
| 76 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36811 | -3.559 | -0.2481 | Yes |
| 77 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36833 | -3.603 | -0.2288 | Yes |
| 78 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36863 | -3.662 | -0.2094 | Yes |
| 79 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36870 | -3.679 | -0.1892 | Yes |
| 80 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36876 | -3.698 | -0.1690 | Yes |
| 81 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36882 | -3.715 | -0.1486 | Yes |
| 82 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36891 | -3.747 | -0.1282 | Yes |
| 83 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36894 | -3.758 | -0.1075 | Yes |
| 84 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36922 | -3.842 | -0.0870 | Yes |
| 85 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36931 | -3.886 | -0.0658 | Yes |
| 86 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36955 | -3.967 | -0.0445 | Yes |
| 87 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 37018 | -4.241 | -0.0228 | Yes |
| 88 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 37059 | -4.485 | 0.0008 | Yes |
