Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_TTK |
| Enrichment Score (ES) | -0.8804312 |
| Normalized Enrichment Score (NES) | -1.6532587 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.542593E-4 |
| FWER p-Value | 0.005 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1902 | 0.962 | -0.0415 | No |
| 2 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 25804 | 0.000 | -0.6866 | No |
| 3 | CCT2 | chaperonin containing TCP1 subunit 2 [Source:HGNC Symbol;Acc:HGNC:1615] | 27190 | -0.012 | -0.7238 | No |
| 4 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29215 | -0.283 | -0.7756 | No |
| 5 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32856 | -0.976 | -0.8638 | No |
| 6 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33245 | -1.087 | -0.8632 | No |
| 7 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 33884 | -1.299 | -0.8672 | Yes |
| 8 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33887 | -1.300 | -0.8539 | Yes |
| 9 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 34079 | -1.367 | -0.8451 | Yes |
| 10 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34588 | -1.576 | -0.8428 | Yes |
| 11 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 35120 | -1.833 | -0.8384 | Yes |
| 12 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35386 | -2.005 | -0.8250 | Yes |
| 13 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35573 | -2.135 | -0.8083 | Yes |
| 14 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35799 | -2.315 | -0.7907 | Yes |
| 15 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35837 | -2.347 | -0.7677 | Yes |
| 16 | CENPU | centromere protein U [Source:HGNC Symbol;Acc:HGNC:21348] | 35859 | -2.368 | -0.7441 | Yes |
| 17 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35861 | -2.370 | -0.7199 | Yes |
| 18 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35874 | -2.384 | -0.6959 | Yes |
| 19 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35901 | -2.411 | -0.6720 | Yes |
| 20 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36076 | -2.578 | -0.6504 | Yes |
| 21 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36339 | -2.870 | -0.6281 | Yes |
| 22 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36383 | -2.908 | -0.5996 | Yes |
| 23 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36425 | -2.957 | -0.5705 | Yes |
| 24 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36586 | -3.138 | -0.5428 | Yes |
| 25 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36611 | -3.176 | -0.5110 | Yes |
| 26 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36622 | -3.191 | -0.4787 | Yes |
| 27 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36630 | -3.207 | -0.4461 | Yes |
| 28 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36663 | -3.250 | -0.4138 | Yes |
| 29 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36709 | -3.356 | -0.3807 | Yes |
| 30 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36811 | -3.559 | -0.3471 | Yes |
| 31 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36868 | -3.675 | -0.3111 | Yes |
| 32 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36870 | -3.679 | -0.2736 | Yes |
| 33 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36876 | -3.698 | -0.2359 | Yes |
| 34 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36882 | -3.715 | -0.1981 | Yes |
| 35 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36894 | -3.758 | -0.1601 | Yes |
| 36 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36922 | -3.842 | -0.1215 | Yes |
| 37 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36931 | -3.886 | -0.0821 | Yes |
| 38 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36955 | -3.967 | -0.0422 | Yes |
| 39 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 37059 | -4.485 | 0.0008 | Yes |
