Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | MODULE_121 |
| Enrichment Score (ES) | 0.6512789 |
| Normalized Enrichment Score (NES) | 1.6713653 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.055561747 |
| FWER p-Value | 0.327 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 1 | 4.975 | 0.0411 | Yes |
| 2 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 2 | 4.972 | 0.0822 | Yes |
| 3 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 4 | 4.962 | 0.1232 | Yes |
| 4 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 13 | 4.920 | 0.1637 | Yes |
| 5 | VEGFC | vascular endothelial growth factor C [Source:HGNC Symbol;Acc:HGNC:12682] | 25 | 4.804 | 0.2031 | Yes |
| 6 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 30 | 4.761 | 0.2424 | Yes |
| 7 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 48 | 4.592 | 0.2799 | Yes |
| 8 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 54 | 4.518 | 0.3171 | Yes |
| 9 | ISG20 | interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] | 65 | 4.413 | 0.3533 | Yes |
| 10 | OSM | oncostatin M [Source:HGNC Symbol;Acc:HGNC:8506] | 138 | 3.873 | 0.3834 | Yes |
| 11 | EDN1 | endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176] | 242 | 3.262 | 0.4076 | Yes |
| 12 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 251 | 3.232 | 0.4341 | Yes |
| 13 | TSPAN3 | tetraspanin 3 [Source:HGNC Symbol;Acc:HGNC:17752] | 379 | 2.675 | 0.4528 | Yes |
| 14 | BCAT1 | branched chain amino acid transaminase 1 [Source:HGNC Symbol;Acc:HGNC:976] | 412 | 2.566 | 0.4731 | Yes |
| 15 | ZEB1 | zinc finger E-box binding homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11642] | 431 | 2.520 | 0.4935 | Yes |
| 16 | IL2RG | interleukin 2 receptor subunit gamma [Source:HGNC Symbol;Acc:HGNC:6010] | 510 | 2.318 | 0.5105 | Yes |
| 17 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 525 | 2.303 | 0.5292 | Yes |
| 18 | MXD1 | MAX dimerization protein 1 [Source:HGNC Symbol;Acc:HGNC:6761] | 538 | 2.270 | 0.5477 | Yes |
| 19 | NAB2 | NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627] | 591 | 2.157 | 0.5641 | Yes |
| 20 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 713 | 1.960 | 0.5770 | Yes |
| 21 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 722 | 1.944 | 0.5929 | Yes |
| 22 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 732 | 1.930 | 0.6086 | Yes |
| 23 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 870 | 1.699 | 0.6189 | Yes |
| 24 | BCL6 | BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001] | 899 | 1.665 | 0.6320 | Yes |
| 25 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 1267 | 1.338 | 0.6331 | Yes |
| 26 | NAMPT | nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092] | 1365 | 1.268 | 0.6410 | Yes |
| 27 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 1607 | 1.113 | 0.6437 | Yes |
| 28 | EVI2A | ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499] | 1671 | 1.072 | 0.6508 | Yes |
| 29 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 1942 | 0.939 | 0.6513 | Yes |
| 30 | KLF6 | Kruppel like factor 6 [Source:HGNC Symbol;Acc:HGNC:2235] | 2383 | 0.770 | 0.6457 | No |
| 31 | HBEGF | heparin binding EGF like growth factor [Source:HGNC Symbol;Acc:HGNC:3059] | 2579 | 0.708 | 0.6463 | No |
| 32 | DAB2 | DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662] | 2690 | 0.671 | 0.6489 | No |
| 33 | MDK | midkine [Source:HGNC Symbol;Acc:HGNC:6972] | 3580 | 0.445 | 0.6286 | No |
| 34 | EMP3 | epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335] | 3914 | 0.376 | 0.6227 | No |
| 35 | PSPHP1 | phosphoserine phosphatase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9578] | 4930 | 0.203 | 0.5969 | No |
| 36 | CDK5R1 | cyclin dependent kinase 5 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:1775] | 5315 | 0.146 | 0.5877 | No |
| 37 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 5493 | 0.121 | 0.5839 | No |
| 38 | AKR1C3 | aldo-keto reductase family 1 member C3 [Source:HGNC Symbol;Acc:HGNC:386] | 5843 | 0.076 | 0.5751 | No |
| 39 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 6399 | 0.000 | 0.5601 | No |
| 40 | AREG | amphiregulin [Source:HGNC Symbol;Acc:HGNC:651] | 7301 | 0.000 | 0.5358 | No |
| 41 | PDGFRA | platelet derived growth factor receptor alpha [Source:HGNC Symbol;Acc:HGNC:8803] | 7521 | 0.000 | 0.5299 | No |
| 42 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8812 | 0.000 | 0.4950 | No |
| 43 | GRPR | gastrin releasing peptide receptor [Source:HGNC Symbol;Acc:HGNC:4609] | 10008 | 0.000 | 0.4627 | No |
| 44 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 10945 | 0.000 | 0.4374 | No |
| 45 | ERBB2 | erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430] | 11956 | 0.000 | 0.4101 | No |
| 46 | TGFA | transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765] | 12441 | 0.000 | 0.3970 | No |
| 47 | IGF2 | insulin like growth factor 2 [Source:HGNC Symbol;Acc:HGNC:5466] | 12457 | 0.000 | 0.3966 | No |
| 48 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12458 | 0.000 | 0.3966 | No |
| 49 | VIP | vasoactive intestinal peptide [Source:HGNC Symbol;Acc:HGNC:12693] | 13132 | 0.000 | 0.3784 | No |
| 50 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 13734 | 0.000 | 0.3621 | No |
| 51 | IL15RA | interleukin 15 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5978] | 14095 | 0.000 | 0.3524 | No |
| 52 | TACSTD2 | tumor associated calcium signal transducer 2 [Source:HGNC Symbol;Acc:HGNC:11530] | 14409 | 0.000 | 0.3440 | No |
| 53 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15729 | 0.000 | 0.3083 | No |
| 54 | CD4 | CD4 molecule [Source:HGNC Symbol;Acc:HGNC:1678] | 15730 | 0.000 | 0.3083 | No |
| 55 | MST1R | macrophage stimulating 1 receptor [Source:HGNC Symbol;Acc:HGNC:7381] | 16213 | 0.000 | 0.2953 | No |
| 56 | FGA | fibrinogen alpha chain [Source:HGNC Symbol;Acc:HGNC:3661] | 16629 | 0.000 | 0.2840 | No |
| 57 | FGG | fibrinogen gamma chain [Source:HGNC Symbol;Acc:HGNC:3694] | 16630 | 0.000 | 0.2840 | No |
| 58 | GCG | glucagon [Source:HGNC Symbol;Acc:HGNC:4191] | 16862 | 0.000 | 0.2778 | No |
| 59 | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251] | 16986 | 0.000 | 0.2745 | No |
| 60 | IL3 | interleukin 3 [Source:HGNC Symbol;Acc:HGNC:6011] | 17625 | 0.000 | 0.2572 | No |
| 61 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 18865 | 0.000 | 0.2237 | No |
| 62 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19318 | 0.000 | 0.2115 | No |
| 63 | PTN | pleiotrophin [Source:HGNC Symbol;Acc:HGNC:9630] | 19973 | 0.000 | 0.1938 | No |
| 64 | EDNRA | endothelin receptor type A [Source:HGNC Symbol;Acc:HGNC:3179] | 21665 | 0.000 | 0.1481 | No |
| 65 | EGR4 | early growth response 4 [Source:HGNC Symbol;Acc:HGNC:3241] | 22028 | 0.000 | 0.1383 | No |
| 66 | SLAMF1 | signaling lymphocytic activation molecule family member 1 [Source:HGNC Symbol;Acc:HGNC:10903] | 22745 | 0.000 | 0.1190 | No |
| 67 | CD8B | CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707] | 22861 | 0.000 | 0.1159 | No |
| 68 | CD8A | CD8a molecule [Source:HGNC Symbol;Acc:HGNC:1706] | 22862 | 0.000 | 0.1159 | No |
| 69 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 24238 | 0.000 | 0.0787 | No |
| 70 | FGF4 | fibroblast growth factor 4 [Source:HGNC Symbol;Acc:HGNC:3682] | 25053 | 0.000 | 0.0567 | No |
| 71 | REG1B | regenerating family member 1 beta [Source:HGNC Symbol;Acc:HGNC:9952] | 26027 | 0.000 | 0.0304 | No |
| 72 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 26724 | 0.000 | 0.0116 | No |
| 73 | GRN | granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601] | 27340 | -0.041 | -0.0047 | No |
| 74 | TGFB3 | transforming growth factor beta 3 [Source:HGNC Symbol;Acc:HGNC:11769] | 27602 | -0.070 | -0.0112 | No |
| 75 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 27834 | -0.101 | -0.0166 | No |
| 76 | VIPR1 | vasoactive intestinal peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:12694] | 28083 | -0.131 | -0.0222 | No |
| 77 | FGB | fibrinogen beta chain [Source:HGNC Symbol;Acc:HGNC:3662] | 28924 | -0.243 | -0.0429 | No |
| 78 | CCN1 | cellular communication network factor 1 [Source:HGNC Symbol;Acc:HGNC:2654] | 29505 | -0.325 | -0.0559 | No |
| 79 | IL6R | interleukin 6 receptor [Source:HGNC Symbol;Acc:HGNC:6019] | 30010 | -0.398 | -0.0662 | No |
| 80 | FGF7 | fibroblast growth factor 7 [Source:HGNC Symbol;Acc:HGNC:3685] | 30191 | -0.427 | -0.0676 | No |
| 81 | EPHB4 | EPH receptor B4 [Source:HGNC Symbol;Acc:HGNC:3395] | 30205 | -0.429 | -0.0644 | No |
| 82 | EGF | epidermal growth factor [Source:HGNC Symbol;Acc:HGNC:3229] | 31269 | -0.602 | -0.0881 | No |
| 83 | IGF1 | insulin like growth factor 1 [Source:HGNC Symbol;Acc:HGNC:5464] | 32080 | -0.781 | -0.1036 | No |
| 84 | SFN | stratifin [Source:HGNC Symbol;Acc:HGNC:10773] | 32221 | -0.813 | -0.1006 | No |
| 85 | CRIP1 | cysteine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:2360] | 32955 | -1.002 | -0.1122 | No |
| 86 | ERG | ETS transcription factor ERG [Source:HGNC Symbol;Acc:HGNC:3446] | 33466 | -1.158 | -0.1164 | No |
| 87 | BCAR1 | BCAR1 scaffold protein, Cas family member [Source:HGNC Symbol;Acc:HGNC:971] | 33573 | -1.193 | -0.1094 | No |
| 88 | MAPRE2 | microtubule associated protein RP/EB family member 2 [Source:HGNC Symbol;Acc:HGNC:6891] | 34073 | -1.365 | -0.1116 | No |
| 89 | RUNX3 | RUNX family transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10473] | 34150 | -1.392 | -0.1021 | No |
| 90 | CSRP2 | cysteine and glycine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2470] | 34328 | -1.470 | -0.0947 | No |
| 91 | INSIG1 | insulin induced gene 1 [Source:HGNC Symbol;Acc:HGNC:6083] | 34467 | -1.529 | -0.0858 | No |
| 92 | GAS6 | growth arrest specific 6 [Source:HGNC Symbol;Acc:HGNC:4168] | 34778 | -1.661 | -0.0805 | No |
| 93 | EMP1 | epithelial membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3333] | 35249 | -1.918 | -0.0773 | No |
| 94 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 35328 | -1.964 | -0.0632 | No |
| 95 | CREG1 | cellular repressor of E1A stimulated genes 1 [Source:HGNC Symbol;Acc:HGNC:2351] | 35657 | -2.205 | -0.0538 | No |
| 96 | LRP1 | LDL receptor related protein 1 [Source:HGNC Symbol;Acc:HGNC:6692] | 35812 | -2.327 | -0.0387 | No |
| 97 | EPS8 | epidermal growth factor receptor pathway substrate 8 [Source:HGNC Symbol;Acc:HGNC:3420] | 35993 | -2.497 | -0.0230 | No |
| 98 | NRP1 | neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004] | 36578 | -3.130 | -0.0129 | No |
| 99 | ZFP36L2 | ZFP36 ring finger protein like 2 [Source:HGNC Symbol;Acc:HGNC:1108] | 36647 | -3.227 | 0.0120 | No |
