Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | MODULE_208 |
| Enrichment Score (ES) | 0.5964076 |
| Normalized Enrichment Score (NES) | 1.558127 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.12604772 |
| FWER p-Value | 0.762 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 8 | 4.948 | 0.0369 | Yes |
| 2 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 13 | 4.920 | 0.0737 | Yes |
| 3 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 35 | 4.721 | 0.1086 | Yes |
| 4 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 55 | 4.511 | 0.1419 | Yes |
| 5 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 67 | 4.389 | 0.1746 | Yes |
| 6 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 82 | 4.215 | 0.2058 | Yes |
| 7 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 85 | 4.196 | 0.2373 | Yes |
| 8 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 92 | 4.151 | 0.2683 | Yes |
| 9 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 103 | 4.085 | 0.2987 | Yes |
| 10 | PELI1 | pellino E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:8827] | 116 | 3.985 | 0.3282 | Yes |
| 11 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 134 | 3.887 | 0.3570 | Yes |
| 12 | CFB | complement factor B [Source:HGNC Symbol;Acc:HGNC:1037] | 182 | 3.590 | 0.3826 | Yes |
| 13 | AQP9 | aquaporin 9 [Source:HGNC Symbol;Acc:HGNC:643] | 217 | 3.381 | 0.4071 | Yes |
| 14 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 230 | 3.311 | 0.4316 | Yes |
| 15 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 254 | 3.217 | 0.4551 | Yes |
| 16 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 285 | 3.080 | 0.4774 | Yes |
| 17 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 457 | 2.456 | 0.4912 | Yes |
| 18 | IFITM2 | interferon induced transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:5413] | 468 | 2.433 | 0.5092 | Yes |
| 19 | KCTD12 | potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678] | 576 | 2.179 | 0.5227 | Yes |
| 20 | RRP15 | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] | 584 | 2.163 | 0.5387 | Yes |
| 21 | NLRC5 | NLR family CARD domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29933] | 614 | 2.127 | 0.5539 | Yes |
| 22 | FOXP1 | forkhead box P1 [Source:HGNC Symbol;Acc:HGNC:3823] | 1131 | 1.445 | 0.5508 | Yes |
| 23 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 1267 | 1.338 | 0.5572 | Yes |
| 24 | CNRIP1 | cannabinoid receptor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24546] | 1406 | 1.241 | 0.5628 | Yes |
| 25 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 1607 | 1.113 | 0.5657 | Yes |
| 26 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 1647 | 1.087 | 0.5728 | Yes |
| 27 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 1724 | 1.043 | 0.5786 | Yes |
| 28 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1775 | 1.020 | 0.5849 | Yes |
| 29 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 1992 | 0.922 | 0.5860 | Yes |
| 30 | MCU | mitochondrial calcium uniporter [Source:HGNC Symbol;Acc:HGNC:23526] | 2097 | 0.879 | 0.5897 | Yes |
| 31 | KLF6 | Kruppel like factor 6 [Source:HGNC Symbol;Acc:HGNC:2235] | 2383 | 0.770 | 0.5878 | Yes |
| 32 | CCDC186 | coiled-coil domain containing 186 [Source:HGNC Symbol;Acc:HGNC:24349] | 2406 | 0.763 | 0.5929 | Yes |
| 33 | P2RY10 | P2Y receptor family member 10 [Source:HGNC Symbol;Acc:HGNC:19906] | 2484 | 0.739 | 0.5964 | Yes |
| 34 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 2780 | 0.644 | 0.5933 | No |
| 35 | PPP1R16B | protein phosphatase 1 regulatory subunit 16B [Source:HGNC Symbol;Acc:HGNC:15850] | 3104 | 0.557 | 0.5887 | No |
| 36 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 4193 | 0.325 | 0.5617 | No |
| 37 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 4195 | 0.324 | 0.5641 | No |
| 38 | CPVL | carboxypeptidase vitellogenic like [Source:HGNC Symbol;Acc:HGNC:14399] | 4398 | 0.288 | 0.5608 | No |
| 39 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 4523 | 0.265 | 0.5594 | No |
| 40 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 4623 | 0.248 | 0.5586 | No |
| 41 | IL2RB | interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009] | 4664 | 0.242 | 0.5594 | No |
| 42 | KLRK1 | killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788] | 4707 | 0.235 | 0.5600 | No |
| 43 | UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [Source:HGNC Symbol;Acc:HGNC:12638] | 4747 | 0.228 | 0.5606 | No |
| 44 | CD200 | CD200 molecule [Source:HGNC Symbol;Acc:HGNC:7203] | 4807 | 0.219 | 0.5607 | No |
| 45 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 5493 | 0.121 | 0.5431 | No |
| 46 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6421 | 0.000 | 0.5180 | No |
| 47 | SDC2 | syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] | 6847 | 0.000 | 0.5065 | No |
| 48 | SELP | selectin P [Source:HGNC Symbol;Acc:HGNC:10721] | 7172 | 0.000 | 0.4977 | No |
| 49 | STAG3 | stromal antigen 3 [Source:HGNC Symbol;Acc:HGNC:11356] | 7829 | 0.000 | 0.4800 | No |
| 50 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 9026 | 0.000 | 0.4476 | No |
| 51 | KCNQ5 | potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299] | 9861 | 0.000 | 0.4251 | No |
| 52 | ADAM19 | ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197] | 9927 | 0.000 | 0.4233 | No |
| 53 | CARD16 | caspase recruitment domain family member 16 [Source:HGNC Symbol;Acc:HGNC:33701] | 9932 | 0.000 | 0.4232 | No |
| 54 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 10073 | 0.000 | 0.4194 | No |
| 55 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2597] | 10553 | 0.000 | 0.4065 | No |
| 56 | MS4A1 | membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315] | 11052 | 0.000 | 0.3930 | No |
| 57 | GZMA | granzyme A [Source:HGNC Symbol;Acc:HGNC:4708] | 12120 | 0.000 | 0.3641 | No |
| 58 | NEK11 | NIMA related kinase 11 [Source:HGNC Symbol;Acc:HGNC:18593] | 12184 | 0.000 | 0.3624 | No |
| 59 | UNC79 | unc-79 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:19966] | 12426 | 0.000 | 0.3559 | No |
| 60 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12430 | 0.000 | 0.3558 | No |
| 61 | IGKC | immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716] | 12491 | 0.000 | 0.3542 | No |
| 62 | LILRB1 | leukocyte immunoglobulin like receptor B1 [Source:HGNC Symbol;Acc:HGNC:6605] | 13392 | 0.000 | 0.3299 | No |
| 63 | TPTE2 | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:HGNC:17299] | 13800 | 0.000 | 0.3189 | No |
| 64 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 13825 | 0.000 | 0.3182 | No |
| 65 | PNMA8A | PNMA family member 8A [Source:HGNC Symbol;Acc:HGNC:25578] | 14553 | 0.000 | 0.2985 | No |
| 66 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15729 | 0.000 | 0.2668 | No |
| 67 | XCL1 | X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10645] | 15839 | 0.000 | 0.2638 | No |
| 68 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16145 | 0.000 | 0.2556 | No |
| 69 | HLA-DRA | major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947] | 16174 | 0.000 | 0.2548 | No |
| 70 | TREM1 | triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760] | 16461 | 0.000 | 0.2471 | No |
| 71 | IL3RA | interleukin 3 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6012] | 16470 | 0.000 | 0.2468 | No |
| 72 | IGHG3 | immunoglobulin heavy constant gamma 3 (G3m marker) [Source:HGNC Symbol;Acc:HGNC:5527] | 17082 | 0.000 | 0.2303 | No |
| 73 | SERPINA5 | serpin family A member 5 [Source:HGNC Symbol;Acc:HGNC:8723] | 17694 | 0.000 | 0.2138 | No |
| 74 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18275 | 0.000 | 0.1981 | No |
| 75 | IGLJ3 | immunoglobulin lambda joining 3 [Source:HGNC Symbol;Acc:HGNC:5865] | 18294 | 0.000 | 0.1976 | No |
| 76 | CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene [Source:HGNC Symbol;Acc:HGNC:2098] | 18575 | 0.000 | 0.1900 | No |
| 77 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 [Source:HGNC Symbol;Acc:HGNC:4938] | 18725 | 0.000 | 0.1860 | No |
| 78 | CXCL13 | C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] | 18748 | 0.000 | 0.1854 | No |
| 79 | MAL | mal, T cell differentiation protein [Source:HGNC Symbol;Acc:HGNC:6817] | 18766 | 0.000 | 0.1850 | No |
| 80 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19306 | 0.000 | 0.1704 | No |
| 81 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 20482 | 0.000 | 0.1386 | No |
| 82 | UNC5D | unc-5 netrin receptor D [Source:HGNC Symbol;Acc:HGNC:18634] | 20676 | 0.000 | 0.1334 | No |
| 83 | CMKLR1 | chemerin chemokine-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:2121] | 22156 | 0.000 | 0.0934 | No |
| 84 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 22199 | 0.000 | 0.0922 | No |
| 85 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22677 | 0.000 | 0.0793 | No |
| 86 | CD3D | CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673] | 22767 | 0.000 | 0.0769 | No |
| 87 | CD48 | CD48 molecule [Source:HGNC Symbol;Acc:HGNC:1683] | 22795 | 0.000 | 0.0762 | No |
| 88 | CD8B | CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707] | 22861 | 0.000 | 0.0744 | No |
| 89 | IFIT5 | interferon induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:HGNC:13328] | 22992 | 0.000 | 0.0709 | No |
| 90 | DEFA1 | defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761] | 23251 | 0.000 | 0.0639 | No |
| 91 | CTSL | cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537] | 24754 | 0.000 | 0.0233 | No |
| 92 | HBA2 | hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824] | 24762 | 0.000 | 0.0231 | No |
| 93 | CD79A | CD79a molecule [Source:HGNC Symbol;Acc:HGNC:1698] | 25193 | 0.000 | 0.0115 | No |
| 94 | STK31 | serine/threonine kinase 31 [Source:HGNC Symbol;Acc:HGNC:11407] | 25462 | 0.000 | 0.0042 | No |
| 95 | HLA-DMB | major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935] | 27921 | -0.112 | -0.0614 | No |
| 96 | AXIN1 | axin 1 [Source:HGNC Symbol;Acc:HGNC:903] | 27949 | -0.116 | -0.0613 | No |
| 97 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:HGNC:4944] | 28576 | -0.196 | -0.0767 | No |
| 98 | TCF7 | transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:11639] | 29437 | -0.317 | -0.0976 | No |
| 99 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 [Source:HGNC Symbol;Acc:HGNC:4940] | 30174 | -0.425 | -0.1143 | No |
| 100 | KIAA0753 | KIAA0753 [Source:HGNC Symbol;Acc:HGNC:29110] | 30682 | -0.503 | -0.1243 | No |
| 101 | TNFRSF25 | TNF receptor superfamily member 25 [Source:HGNC Symbol;Acc:HGNC:11910] | 30879 | -0.537 | -0.1256 | No |
| 102 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 31585 | -0.666 | -0.1396 | No |
| 103 | POLR3B | RNA polymerase III subunit B [Source:HGNC Symbol;Acc:HGNC:30348] | 31791 | -0.713 | -0.1398 | No |
| 104 | KCNA3 | potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221] | 31847 | -0.726 | -0.1359 | No |
| 105 | HVCN1 | hydrogen voltage gated channel 1 [Source:HGNC Symbol;Acc:HGNC:28240] | 31931 | -0.746 | -0.1325 | No |
| 106 | LIMD2 | LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142] | 32756 | -0.949 | -0.1477 | No |
| 107 | BANK1 | B cell scaffold protein with ankyrin repeats 1 [Source:HGNC Symbol;Acc:HGNC:18233] | 32760 | -0.950 | -0.1406 | No |
| 108 | USP30 | ubiquitin specific peptidase 30 [Source:HGNC Symbol;Acc:HGNC:20065] | 32868 | -0.979 | -0.1362 | No |
| 109 | TXLNGY | taxilin gamma pseudogene, Y-linked [Source:HGNC Symbol;Acc:HGNC:18473] | 33377 | -1.131 | -0.1414 | No |
| 110 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 33411 | -1.141 | -0.1338 | No |
| 111 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 33680 | -1.230 | -0.1318 | No |
| 112 | HLA-DMA | major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:HGNC:4934] | 34628 | -1.595 | -0.1454 | No |
| 113 | ZNF292 | zinc finger protein 292 [Source:HGNC Symbol;Acc:HGNC:18410] | 34671 | -1.615 | -0.1344 | No |
| 114 | FAM53B | family with sequence similarity 53 member B [Source:HGNC Symbol;Acc:HGNC:28968] | 34708 | -1.630 | -0.1232 | No |
| 115 | ABTB1 | ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275] | 35486 | -2.073 | -0.1286 | No |
| 116 | SLC40A1 | solute carrier family 40 member 1 [Source:HGNC Symbol;Acc:HGNC:10909] | 35718 | -2.252 | -0.1180 | No |
| 117 | S1PR1 | sphingosine-1-phosphate receptor 1 [Source:HGNC Symbol;Acc:HGNC:3165] | 35738 | -2.268 | -0.1015 | No |
| 118 | TTC30A | tetratricopeptide repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:25853] | 35786 | -2.305 | -0.0854 | No |
| 119 | GMCL1 | germ cell-less 1, spermatogenesis associated [Source:HGNC Symbol;Acc:HGNC:23843] | 36272 | -2.786 | -0.0777 | No |
| 120 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 36400 | -2.929 | -0.0591 | No |
| 121 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 36426 | -2.958 | -0.0376 | No |
| 122 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 36694 | -3.323 | -0.0199 | No |
| 123 | IGHM | immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541] | 36986 | -4.071 | 0.0028 | No |
