Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | MODULE_345 |
| Enrichment Score (ES) | 0.6763551 |
| Normalized Enrichment Score (NES) | 1.8035712 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.01947811 |
| FWER p-Value | 0.045 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 6 | 4.960 | 0.0343 | Yes |
| 2 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 8 | 4.948 | 0.0686 | Yes |
| 3 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 13 | 4.920 | 0.1027 | Yes |
| 4 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 31 | 4.755 | 0.1353 | Yes |
| 5 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 55 | 4.511 | 0.1660 | Yes |
| 6 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 67 | 4.389 | 0.1962 | Yes |
| 7 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 82 | 4.215 | 0.2251 | Yes |
| 8 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 85 | 4.196 | 0.2541 | Yes |
| 9 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 92 | 4.151 | 0.2828 | Yes |
| 10 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 103 | 4.085 | 0.3109 | Yes |
| 11 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 112 | 4.003 | 0.3385 | Yes |
| 12 | PELI1 | pellino E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:8827] | 116 | 3.985 | 0.3661 | Yes |
| 13 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 134 | 3.887 | 0.3926 | Yes |
| 14 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 198 | 3.495 | 0.4152 | Yes |
| 15 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 201 | 3.473 | 0.4393 | Yes |
| 16 | AQP9 | aquaporin 9 [Source:HGNC Symbol;Acc:HGNC:643] | 217 | 3.381 | 0.4623 | Yes |
| 17 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 230 | 3.311 | 0.4850 | Yes |
| 18 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 254 | 3.217 | 0.5067 | Yes |
| 19 | POU2F2 | POU class 2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9213] | 257 | 3.211 | 0.5290 | Yes |
| 20 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 285 | 3.080 | 0.5496 | Yes |
| 21 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 400 | 2.600 | 0.5646 | Yes |
| 22 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 457 | 2.456 | 0.5802 | Yes |
| 23 | KCTD12 | potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678] | 576 | 2.179 | 0.5921 | Yes |
| 24 | RRP15 | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] | 584 | 2.163 | 0.6069 | Yes |
| 25 | UBE2L6 | ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490] | 618 | 2.114 | 0.6207 | Yes |
| 26 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 850 | 1.724 | 0.6264 | Yes |
| 27 | HLA-A | major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931] | 1007 | 1.543 | 0.6329 | Yes |
| 28 | FOXP1 | forkhead box P1 [Source:HGNC Symbol;Acc:HGNC:3823] | 1131 | 1.445 | 0.6397 | Yes |
| 29 | CNRIP1 | cannabinoid receptor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24546] | 1406 | 1.241 | 0.6409 | Yes |
| 30 | BLNK | B cell linker [Source:HGNC Symbol;Acc:HGNC:14211] | 1593 | 1.126 | 0.6436 | Yes |
| 31 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 1607 | 1.113 | 0.6510 | Yes |
| 32 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 1647 | 1.087 | 0.6575 | Yes |
| 33 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 1724 | 1.043 | 0.6627 | Yes |
| 34 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1775 | 1.020 | 0.6684 | Yes |
| 35 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 1992 | 0.922 | 0.6690 | Yes |
| 36 | FCRL2 | Fc receptor like 2 [Source:HGNC Symbol;Acc:HGNC:14875] | 2376 | 0.773 | 0.6640 | Yes |
| 37 | CCDC186 | coiled-coil domain containing 186 [Source:HGNC Symbol;Acc:HGNC:24349] | 2406 | 0.763 | 0.6685 | Yes |
| 38 | P2RY10 | P2Y receptor family member 10 [Source:HGNC Symbol;Acc:HGNC:19906] | 2484 | 0.739 | 0.6716 | Yes |
| 39 | ZNF436 | zinc finger protein 436 [Source:HGNC Symbol;Acc:HGNC:20814] | 2497 | 0.734 | 0.6764 | Yes |
| 40 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 2780 | 0.644 | 0.6732 | No |
| 41 | PPP1R16B | protein phosphatase 1 regulatory subunit 16B [Source:HGNC Symbol;Acc:HGNC:15850] | 3104 | 0.557 | 0.6683 | No |
| 42 | SPIB | Spi-B transcription factor [Source:HGNC Symbol;Acc:HGNC:11242] | 3447 | 0.471 | 0.6623 | No |
| 43 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 3904 | 0.378 | 0.6526 | No |
| 44 | UNKL | unk like zinc finger [Source:HGNC Symbol;Acc:HGNC:14184] | 4171 | 0.328 | 0.6477 | No |
| 45 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 4193 | 0.325 | 0.6494 | No |
| 46 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 4195 | 0.324 | 0.6516 | No |
| 47 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 4623 | 0.248 | 0.6418 | No |
| 48 | IL2RB | interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009] | 4664 | 0.242 | 0.6424 | No |
| 49 | KLRK1 | killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788] | 4707 | 0.235 | 0.6429 | No |
| 50 | UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [Source:HGNC Symbol;Acc:HGNC:12638] | 4747 | 0.228 | 0.6434 | No |
| 51 | UNC13B | unc-13 homolog B [Source:HGNC Symbol;Acc:HGNC:12566] | 5343 | 0.141 | 0.6283 | No |
| 52 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 5493 | 0.121 | 0.6251 | No |
| 53 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6421 | 0.000 | 0.6000 | No |
| 54 | SDC2 | syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] | 6847 | 0.000 | 0.5885 | No |
| 55 | SELL | selectin L [Source:HGNC Symbol;Acc:HGNC:10720] | 7173 | 0.000 | 0.5798 | No |
| 56 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 9026 | 0.000 | 0.5297 | No |
| 57 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9670 | 0.000 | 0.5123 | No |
| 58 | KCNQ5 | potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299] | 9861 | 0.000 | 0.5071 | No |
| 59 | ADAM19 | ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197] | 9927 | 0.000 | 0.5054 | No |
| 60 | CARD16 | caspase recruitment domain family member 16 [Source:HGNC Symbol;Acc:HGNC:33701] | 9932 | 0.000 | 0.5053 | No |
| 61 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 10073 | 0.000 | 0.5015 | No |
| 62 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2597] | 10553 | 0.000 | 0.4885 | No |
| 63 | MS4A1 | membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315] | 11052 | 0.000 | 0.4750 | No |
| 64 | NEK11 | NIMA related kinase 11 [Source:HGNC Symbol;Acc:HGNC:18593] | 12184 | 0.000 | 0.4444 | No |
| 65 | UNC79 | unc-79 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:19966] | 12426 | 0.000 | 0.4379 | No |
| 66 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12430 | 0.000 | 0.4378 | No |
| 67 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12458 | 0.000 | 0.4371 | No |
| 68 | IGKC | immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716] | 12491 | 0.000 | 0.4362 | No |
| 69 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 13043 | 0.000 | 0.4213 | No |
| 70 | TPTE2 | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:HGNC:17299] | 13800 | 0.000 | 0.4009 | No |
| 71 | PNMA8A | PNMA family member 8A [Source:HGNC Symbol;Acc:HGNC:25578] | 14553 | 0.000 | 0.3805 | No |
| 72 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15729 | 0.000 | 0.3488 | No |
| 73 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16145 | 0.000 | 0.3375 | No |
| 74 | HLA-DRA | major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947] | 16174 | 0.000 | 0.3368 | No |
| 75 | MST1L | macrophage stimulating 1 like [Source:HGNC Symbol;Acc:HGNC:7390] | 16214 | 0.000 | 0.3357 | No |
| 76 | TREM1 | triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760] | 16461 | 0.000 | 0.3291 | No |
| 77 | IL3RA | interleukin 3 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6012] | 16470 | 0.000 | 0.3288 | No |
| 78 | IGHG3 | immunoglobulin heavy constant gamma 3 (G3m marker) [Source:HGNC Symbol;Acc:HGNC:5527] | 17082 | 0.000 | 0.3123 | No |
| 79 | SERPINA5 | serpin family A member 5 [Source:HGNC Symbol;Acc:HGNC:8723] | 17694 | 0.000 | 0.2958 | No |
| 80 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18275 | 0.000 | 0.2801 | No |
| 81 | IGLJ3 | immunoglobulin lambda joining 3 [Source:HGNC Symbol;Acc:HGNC:5865] | 18294 | 0.000 | 0.2796 | No |
| 82 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18322 | 0.000 | 0.2789 | No |
| 83 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 [Source:HGNC Symbol;Acc:HGNC:4938] | 18725 | 0.000 | 0.2680 | No |
| 84 | MAL | mal, T cell differentiation protein [Source:HGNC Symbol;Acc:HGNC:6817] | 18766 | 0.000 | 0.2669 | No |
| 85 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19306 | 0.000 | 0.2523 | No |
| 86 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 20482 | 0.000 | 0.2206 | No |
| 87 | UNC5D | unc-5 netrin receptor D [Source:HGNC Symbol;Acc:HGNC:18634] | 20676 | 0.000 | 0.2153 | No |
| 88 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 22199 | 0.000 | 0.1742 | No |
| 89 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22677 | 0.000 | 0.1613 | No |
| 90 | CD19 | CD19 molecule [Source:HGNC Symbol;Acc:HGNC:1633] | 22739 | 0.000 | 0.1596 | No |
| 91 | CD27 | CD27 molecule [Source:HGNC Symbol;Acc:HGNC:11922] | 22756 | 0.000 | 0.1592 | No |
| 92 | CD3D | CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673] | 22767 | 0.000 | 0.1589 | No |
| 93 | UCP1 | uncoupling protein 1 [Source:HGNC Symbol;Acc:HGNC:12517] | 23165 | 0.000 | 0.1482 | No |
| 94 | DEFA1 | defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761] | 23251 | 0.000 | 0.1459 | No |
| 95 | ADGRE2 | adhesion G protein-coupled receptor E2 [Source:HGNC Symbol;Acc:HGNC:3337] | 24089 | 0.000 | 0.1232 | No |
| 96 | CTSL | cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537] | 24754 | 0.000 | 0.1053 | No |
| 97 | HBA2 | hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824] | 24762 | 0.000 | 0.1051 | No |
| 98 | CD79B | CD79b molecule [Source:HGNC Symbol;Acc:HGNC:1699] | 25192 | 0.000 | 0.0935 | No |
| 99 | CD79A | CD79a molecule [Source:HGNC Symbol;Acc:HGNC:1698] | 25193 | 0.000 | 0.0935 | No |
| 100 | STK31 | serine/threonine kinase 31 [Source:HGNC Symbol;Acc:HGNC:11407] | 25462 | 0.000 | 0.0862 | No |
| 101 | SLC22A23 | solute carrier family 22 member 23 [Source:HGNC Symbol;Acc:HGNC:21106] | 26376 | 0.000 | 0.0615 | No |
| 102 | HLA-DMB | major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935] | 27921 | -0.112 | 0.0205 | No |
| 103 | AXIN1 | axin 1 [Source:HGNC Symbol;Acc:HGNC:903] | 27949 | -0.116 | 0.0206 | No |
| 104 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:HGNC:4944] | 28576 | -0.196 | 0.0050 | No |
| 105 | FCRLA | Fc receptor like A [Source:HGNC Symbol;Acc:HGNC:18504] | 29114 | -0.270 | -0.0076 | No |
| 106 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 [Source:HGNC Symbol;Acc:HGNC:4940] | 30174 | -0.425 | -0.0333 | No |
| 107 | MECP2 | methyl-CpG binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6990] | 30317 | -0.444 | -0.0341 | No |
| 108 | CD37 | CD37 molecule [Source:HGNC Symbol;Acc:HGNC:1666] | 30664 | -0.500 | -0.0400 | No |
| 109 | KIAA0753 | KIAA0753 [Source:HGNC Symbol;Acc:HGNC:29110] | 30682 | -0.503 | -0.0369 | No |
| 110 | TNFRSF25 | TNF receptor superfamily member 25 [Source:HGNC Symbol;Acc:HGNC:11910] | 30879 | -0.537 | -0.0385 | No |
| 111 | POLR3B | RNA polymerase III subunit B [Source:HGNC Symbol;Acc:HGNC:30348] | 31791 | -0.713 | -0.0582 | No |
| 112 | HVCN1 | hydrogen voltage gated channel 1 [Source:HGNC Symbol;Acc:HGNC:28240] | 31931 | -0.746 | -0.0568 | No |
| 113 | RUBCNL | rubicon like autophagy enhancer [Source:HGNC Symbol;Acc:HGNC:20420] | 32741 | -0.945 | -0.0721 | No |
| 114 | LIMD2 | LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142] | 32756 | -0.949 | -0.0659 | No |
| 115 | BANK1 | B cell scaffold protein with ankyrin repeats 1 [Source:HGNC Symbol;Acc:HGNC:18233] | 32760 | -0.950 | -0.0594 | No |
| 116 | TXLNGY | taxilin gamma pseudogene, Y-linked [Source:HGNC Symbol;Acc:HGNC:18473] | 33377 | -1.131 | -0.0682 | No |
| 117 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 33411 | -1.141 | -0.0612 | No |
| 118 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 33680 | -1.230 | -0.0599 | No |
| 119 | HLA-DMA | major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:HGNC:4934] | 34628 | -1.595 | -0.0744 | No |
| 120 | FAM53B | family with sequence similarity 53 member B [Source:HGNC Symbol;Acc:HGNC:28968] | 34708 | -1.630 | -0.0652 | No |
| 121 | ABTB1 | ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275] | 35486 | -2.073 | -0.0718 | No |
| 122 | TTC30A | tetratricopeptide repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:25853] | 35786 | -2.305 | -0.0639 | No |
| 123 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 36426 | -2.958 | -0.0607 | No |
| 124 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 36694 | -3.323 | -0.0448 | No |
| 125 | ATP2A3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 [Source:HGNC Symbol;Acc:HGNC:813] | 36941 | -3.914 | -0.0243 | No |
| 126 | IGHM | immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541] | 36986 | -4.071 | 0.0028 | No |
