Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | GOBP_ACUTE_PHASE_RESPONSE |
| Enrichment Score (ES) | 0.83732593 |
| Normalized Enrichment Score (NES) | 1.898667 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.00781865 |
| FWER p-Value | 0.06 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 2 | 4.972 | 0.1222 | Yes |
| 2 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 4 | 4.962 | 0.2442 | Yes |
| 3 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 7 | 4.952 | 0.3660 | Yes |
| 4 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 51 | 4.548 | 0.4767 | Yes |
| 5 | ASS1 | argininosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:758] | 91 | 4.153 | 0.5777 | Yes |
| 6 | SAA1 | serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513] | 259 | 3.209 | 0.6521 | Yes |
| 7 | SAA2 | serum amyloid A2 [Source:HGNC Symbol;Acc:HGNC:10514] | 430 | 2.523 | 0.7096 | Yes |
| 8 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 490 | 2.381 | 0.7665 | Yes |
| 9 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 732 | 1.930 | 0.8075 | Yes |
| 10 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 1226 | 1.371 | 0.8279 | Yes |
| 11 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 1800 | 1.011 | 0.8373 | Yes |
| 12 | SERPINF2 | serpin family F member 2 [Source:HGNC Symbol;Acc:HGNC:9075] | 4179 | 0.326 | 0.7812 | No |
| 13 | HP | haptoglobin [Source:HGNC Symbol;Acc:HGNC:5141] | 4422 | 0.284 | 0.7816 | No |
| 14 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 4523 | 0.265 | 0.7854 | No |
| 15 | HFE | homeostatic iron regulator [Source:HGNC Symbol;Acc:HGNC:4886] | 4812 | 0.218 | 0.7830 | No |
| 16 | FN1 | fibronectin 1 [Source:HGNC Symbol;Acc:HGNC:3778] | 5802 | 0.082 | 0.7583 | No |
| 17 | SAA4 | serum amyloid A4, constitutive [Source:HGNC Symbol;Acc:HGNC:10516] | 6365 | 0.000 | 0.7432 | No |
| 18 | APCS | amyloid P component, serum [Source:HGNC Symbol;Acc:HGNC:584] | 6692 | 0.000 | 0.7344 | No |
| 19 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 7733 | 0.000 | 0.7063 | No |
| 20 | APOL2 | apolipoprotein L2 [Source:HGNC Symbol;Acc:HGNC:619] | 10074 | 0.000 | 0.6431 | No |
| 21 | CNR1 | cannabinoid receptor 1 [Source:HGNC Symbol;Acc:HGNC:2159] | 12264 | 0.000 | 0.5840 | No |
| 22 | AHSG | alpha 2-HS glycoprotein [Source:HGNC Symbol;Acc:HGNC:349] | 12343 | 0.000 | 0.5819 | No |
| 23 | TNFSF11 | TNF superfamily member 11 [Source:HGNC Symbol;Acc:HGNC:11926] | 12431 | 0.000 | 0.5796 | No |
| 24 | IL22 | interleukin 22 [Source:HGNC Symbol;Acc:HGNC:14900] | 13710 | 0.000 | 0.5451 | No |
| 25 | MBL2 | mannose binding lectin 2 [Source:HGNC Symbol;Acc:HGNC:6922] | 15587 | 0.000 | 0.4944 | No |
| 26 | CRP | C-reactive protein [Source:HGNC Symbol;Acc:HGNC:2367] | 15842 | 0.000 | 0.4876 | No |
| 27 | F2 | coagulation factor II, thrombin [Source:HGNC Symbol;Acc:HGNC:3535] | 16113 | 0.000 | 0.4803 | No |
| 28 | EPO | erythropoietin [Source:HGNC Symbol;Acc:HGNC:3415] | 16427 | 0.000 | 0.4718 | No |
| 29 | INS | insulin [Source:HGNC Symbol;Acc:HGNC:6081] | 17652 | 0.000 | 0.4388 | No |
| 30 | SERPINA1 | serpin family A member 1 [Source:HGNC Symbol;Acc:HGNC:8941] | 17687 | 0.000 | 0.4379 | No |
| 31 | LBP | lipopolysaccharide binding protein [Source:HGNC Symbol;Acc:HGNC:6517] | 18376 | 0.000 | 0.4193 | No |
| 32 | ORM1 | orosomucoid 1 [Source:HGNC Symbol;Acc:HGNC:8498] | 18511 | 0.000 | 0.4157 | No |
| 33 | ORM2 | orosomucoid 2 [Source:HGNC Symbol;Acc:HGNC:8499] | 18512 | 0.000 | 0.4157 | No |
| 34 | MRGPRX1 | MAS related GPR family member X1 [Source:HGNC Symbol;Acc:HGNC:17962] | 19333 | 0.000 | 0.3936 | No |
| 35 | PTGER3 | prostaglandin E receptor 3 [Source:HGNC Symbol;Acc:HGNC:9595] | 19971 | 0.000 | 0.3764 | No |
| 36 | TFR2 | transferrin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11762] | 20688 | 0.000 | 0.3570 | No |
| 37 | EDNRB | endothelin receptor type B [Source:HGNC Symbol;Acc:HGNC:3180] | 21666 | 0.000 | 0.3307 | No |
| 38 | HAMP | hepcidin antimicrobial peptide [Source:HGNC Symbol;Acc:HGNC:15598] | 24595 | 0.000 | 0.2516 | No |
| 39 | REG3A | regenerating family member 3 alpha [Source:HGNC Symbol;Acc:HGNC:8601] | 26042 | 0.000 | 0.2126 | No |
| 40 | REG3G | regenerating family member 3 gamma [Source:HGNC Symbol;Acc:HGNC:29595] | 26046 | 0.000 | 0.2125 | No |
| 41 | UGT1A1 | UDP glucuronosyltransferase family 1 member A1 [Source:HGNC Symbol;Acc:HGNC:12530] | 26276 | 0.000 | 0.2063 | No |
| 42 | ITIH4 | inter-alpha-trypsin inhibitor heavy chain 4 [Source:HGNC Symbol;Acc:HGNC:6169] | 26553 | 0.000 | 0.1989 | No |
| 43 | IL6R | interleukin 6 receptor [Source:HGNC Symbol;Acc:HGNC:6019] | 30010 | -0.398 | 0.1154 | No |
| 44 | F8 | coagulation factor VIII [Source:HGNC Symbol;Acc:HGNC:3546] | 31667 | -0.683 | 0.0875 | No |
| 45 | TNFRSF11A | TNF receptor superfamily member 11a [Source:HGNC Symbol;Acc:HGNC:11908] | 33263 | -1.095 | 0.0714 | No |
| 46 | SIGIRR | single Ig and TIR domain containing [Source:HGNC Symbol;Acc:HGNC:30575] | 33880 | -1.298 | 0.0867 | No |
