Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GOBP_HOMOLOGOUS_CHROMOSOME_SEGREGATION |
| Enrichment Score (ES) | -0.79953414 |
| Normalized Enrichment Score (NES) | -1.5877413 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.063013054 |
| FWER p-Value | 0.539 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PTTG3P | pituitary tumor-transforming 3, pseudogene [Source:HGNC Symbol;Acc:HGNC:13422] | 4519 | 0.265 | -0.1160 | No |
| 2 | MAJIN | membrane anchored junction protein [Source:HGNC Symbol;Acc:HGNC:27441] | 4935 | 0.202 | -0.1226 | No |
| 3 | MSH4 | mutS homolog 4 [Source:HGNC Symbol;Acc:HGNC:7327] | 5509 | 0.119 | -0.1353 | No |
| 4 | RNF212 | ring finger protein 212 [Source:HGNC Symbol;Acc:HGNC:27729] | 5747 | 0.089 | -0.1397 | No |
| 5 | UBE2B | ubiquitin conjugating enzyme E2 B [Source:HGNC Symbol;Acc:HGNC:12473] | 6332 | 0.005 | -0.1554 | No |
| 6 | ANKRD31 | ankyrin repeat domain 31 [Source:HGNC Symbol;Acc:HGNC:26853] | 7677 | 0.000 | -0.1917 | No |
| 7 | STAG3 | stromal antigen 3 [Source:HGNC Symbol;Acc:HGNC:11356] | 7829 | 0.000 | -0.1957 | No |
| 8 | PTTG2 | pituitary tumor-transforming 2 [Source:HGNC Symbol;Acc:HGNC:9691] | 7897 | 0.000 | -0.1975 | No |
| 9 | RAD21L1 | RAD21 cohesin complex component like 1 [Source:HGNC Symbol;Acc:HGNC:16271] | 8048 | 0.000 | -0.2016 | No |
| 10 | C1orf146 | chromosome 1 open reading frame 146 [Source:HGNC Symbol;Acc:HGNC:24032] | 10120 | 0.000 | -0.2575 | No |
| 11 | MEIOC | meiosis specific with coiled-coil domain [Source:HGNC Symbol;Acc:HGNC:26670] | 10760 | 0.000 | -0.2748 | No |
| 12 | RNF212B | ring finger protein 212B [Source:HGNC Symbol;Acc:HGNC:20438] | 11579 | 0.000 | -0.2969 | No |
| 13 | IHO1 | interactor of HORMAD1 1 [Source:HGNC Symbol;Acc:HGNC:27945] | 12755 | 0.000 | -0.3286 | No |
| 14 | MEIKIN | meiotic kinetochore factor [Source:HGNC Symbol;Acc:HGNC:51253] | 12813 | 0.000 | -0.3301 | No |
| 15 | TERB1 | telomere repeat binding bouquet formation protein 1 [Source:HGNC Symbol;Acc:HGNC:26675] | 13096 | 0.000 | -0.3378 | No |
| 16 | TERB2 | telomere repeat binding bouquet formation protein 2 [Source:HGNC Symbol;Acc:HGNC:28520] | 13097 | 0.000 | -0.3378 | No |
| 17 | REC8 | REC8 meiotic recombination protein [Source:HGNC Symbol;Acc:HGNC:16879] | 13643 | 0.000 | -0.3525 | No |
| 18 | TEX11 | testis expressed 11 [Source:HGNC Symbol;Acc:HGNC:11733] | 15151 | 0.000 | -0.3932 | No |
| 19 | TEX12 | testis expressed 12 [Source:HGNC Symbol;Acc:HGNC:11734] | 15152 | 0.000 | -0.3932 | No |
| 20 | TEX15 | testis expressed 15, meiosis and synapsis associated [Source:HGNC Symbol;Acc:HGNC:11738] | 15153 | 0.000 | -0.3932 | No |
| 21 | MEI4 | meiotic double-stranded break formation protein 4 [Source:HGNC Symbol;Acc:HGNC:43638] | 16349 | 0.000 | -0.4254 | No |
| 22 | DMC1 | DNA meiotic recombinase 1 [Source:HGNC Symbol;Acc:HGNC:2927] | 16834 | 0.000 | -0.4385 | No |
| 23 | SYCE3 | synaptonemal complex central element protein 3 [Source:HGNC Symbol;Acc:HGNC:35245] | 16918 | 0.000 | -0.4407 | No |
| 24 | SYCE1 | synaptonemal complex central element protein 1 [Source:HGNC Symbol;Acc:HGNC:28852] | 16919 | 0.000 | -0.4407 | No |
| 25 | SYCP2 | synaptonemal complex protein 2 [Source:HGNC Symbol;Acc:HGNC:11490] | 17750 | 0.000 | -0.4632 | No |
| 26 | SYCP1 | synaptonemal complex protein 1 [Source:HGNC Symbol;Acc:HGNC:11487] | 17751 | 0.000 | -0.4632 | No |
| 27 | CCNB1IP1 | cyclin B1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:19437] | 18196 | 0.000 | -0.4752 | No |
| 28 | P3H4 | prolyl 3-hydroxylase family member 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:16946] | 18444 | 0.000 | -0.4818 | No |
| 29 | SPO11 | SPO11 initiator of meiotic double stranded breaks [Source:HGNC Symbol;Acc:HGNC:11250] | 19312 | 0.000 | -0.5052 | No |
| 30 | C14orf39 | chromosome 14 open reading frame 39 [Source:HGNC Symbol;Acc:HGNC:19849] | 19546 | 0.000 | -0.5115 | No |
| 31 | SYCE1L | synaptonemal complex central element protein 1 like [Source:HGNC Symbol;Acc:HGNC:37236] | 22452 | 0.000 | -0.5900 | No |
| 32 | SPATA22 | spermatogenesis associated 22 [Source:HGNC Symbol;Acc:HGNC:30705] | 24731 | 0.000 | -0.6515 | No |
| 33 | FMN2 | formin 2 [Source:HGNC Symbol;Acc:HGNC:14074] | 26734 | 0.000 | -0.7056 | No |
| 34 | MAEL | maelstrom spermatogenic transposon silencer [Source:HGNC Symbol;Acc:HGNC:25929] | 26802 | 0.000 | -0.7074 | No |
| 35 | BAG6 | BAG cochaperone 6 [Source:HGNC Symbol;Acc:HGNC:13919] | 27312 | -0.037 | -0.7203 | No |
| 36 | HORMAD1 | HORMA domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25245] | 28939 | -0.245 | -0.7586 | No |
| 37 | KASH5 | KASH domain containing 5 [Source:HGNC Symbol;Acc:HGNC:26520] | 30214 | -0.430 | -0.7832 | No |
| 38 | MEIOB | meiosis specific with OB-fold [Source:HGNC Symbol;Acc:HGNC:28569] | 30271 | -0.438 | -0.7747 | No |
| 39 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 30731 | -0.511 | -0.7755 | No |
| 40 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 31585 | -0.666 | -0.7834 | Yes |
| 41 | ZCWPW1 | zinc finger CW-type and PWWP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23486] | 32185 | -0.805 | -0.7812 | Yes |
| 42 | CENPC | centromere protein C [Source:HGNC Symbol;Acc:HGNC:1854] | 32733 | -0.943 | -0.7745 | Yes |
| 43 | NDC1 | NDC1 transmembrane nucleoporin [Source:HGNC Symbol;Acc:HGNC:25525] | 33125 | -1.054 | -0.7611 | Yes |
| 44 | SIRT7 | sirtuin 7 [Source:HGNC Symbol;Acc:HGNC:14935] | 33286 | -1.104 | -0.7402 | Yes |
| 45 | BRIP1 | BRCA1 interacting protein C-terminal helicase 1 [Source:HGNC Symbol;Acc:HGNC:20473] | 33729 | -1.244 | -0.7238 | Yes |
| 46 | ATM | ATM serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:795] | 34125 | -1.385 | -0.7030 | Yes |
| 47 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 34333 | -1.473 | -0.6750 | Yes |
| 48 | MLH1 | mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127] | 34741 | -1.644 | -0.6486 | Yes |
| 49 | MRE11 | MRE11 homolog, double strand break repair nuclease [Source:HGNC Symbol;Acc:HGNC:7230] | 34836 | -1.689 | -0.6127 | Yes |
| 50 | PRDM9 | PR/SET domain 9 [Source:HGNC Symbol;Acc:HGNC:13994] | 35397 | -2.010 | -0.5820 | Yes |
| 51 | FANCD2 | FA complementation group D2 [Source:HGNC Symbol;Acc:HGNC:3585] | 35587 | -2.146 | -0.5383 | Yes |
| 52 | RAD21 | RAD21 cohesin complex component [Source:HGNC Symbol;Acc:HGNC:9811] | 35640 | -2.191 | -0.4898 | Yes |
| 53 | MLH3 | mutL homolog 3 [Source:HGNC Symbol;Acc:HGNC:7128] | 35679 | -2.218 | -0.4403 | Yes |
| 54 | AGO4 | argonaute RISC component 4 [Source:HGNC Symbol;Acc:HGNC:18424] | 35838 | -2.349 | -0.3911 | Yes |
| 55 | SGO1 | shugoshin 1 [Source:HGNC Symbol;Acc:HGNC:25088] | 36030 | -2.528 | -0.3387 | Yes |
| 56 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 36261 | -2.777 | -0.2816 | Yes |
| 57 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36344 | -2.872 | -0.2185 | Yes |
| 58 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 36478 | -3.003 | -0.1537 | Yes |
| 59 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36483 | -3.006 | -0.0853 | Yes |
| 60 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 37055 | -4.466 | 0.0009 | Yes |
