Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GOBP_SEROTONIN_RECEPTOR_SIGNALING_PATHWAY |
| Enrichment Score (ES) | -0.8893723 |
| Normalized Enrichment Score (NES) | -1.6635596 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.008464219 |
| FWER p-Value | 0.046 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | HRH1 | histamine receptor H1 [Source:HGNC Symbol;Acc:HGNC:5182] | 4884 | 0.209 | -0.1028 | No |
| 2 | HTR2B | 5-hydroxytryptamine receptor 2B [Source:HGNC Symbol;Acc:HGNC:5294] | 5761 | 0.087 | -0.1143 | No |
| 3 | HTR2C | 5-hydroxytryptamine receptor 2C [Source:HGNC Symbol;Acc:HGNC:5295] | 6079 | 0.041 | -0.1172 | No |
| 4 | OR6T1 | olfactory receptor family 6 subfamily T member 1 [Source:HGNC Symbol;Acc:HGNC:14848] | 14314 | 0.000 | -0.3394 | No |
| 5 | OR5T3 | olfactory receptor family 5 subfamily T member 3 [Source:HGNC Symbol;Acc:HGNC:15297] | 14757 | 0.000 | -0.3513 | No |
| 6 | OR5T2 | olfactory receptor family 5 subfamily T member 2 [Source:HGNC Symbol;Acc:HGNC:15296] | 14759 | 0.000 | -0.3513 | No |
| 7 | HTR4 | 5-hydroxytryptamine receptor 4 [Source:HGNC Symbol;Acc:HGNC:5299] | 15513 | 0.000 | -0.3717 | No |
| 8 | HTR6 | 5-hydroxytryptamine receptor 6 [Source:HGNC Symbol;Acc:HGNC:5301] | 15515 | 0.000 | -0.3717 | No |
| 9 | HTR7 | 5-hydroxytryptamine receptor 7 [Source:HGNC Symbol;Acc:HGNC:5302] | 15516 | 0.000 | -0.3717 | No |
| 10 | HTR1E | 5-hydroxytryptamine receptor 1E [Source:HGNC Symbol;Acc:HGNC:5291] | 15576 | 0.000 | -0.3733 | No |
| 11 | HTR1F | 5-hydroxytryptamine receptor 1F [Source:HGNC Symbol;Acc:HGNC:5292] | 15578 | 0.000 | -0.3733 | No |
| 12 | HTR1D | 5-hydroxytryptamine receptor 1D [Source:HGNC Symbol;Acc:HGNC:5289] | 15579 | 0.000 | -0.3733 | No |
| 13 | HTR1A | 5-hydroxytryptamine receptor 1A [Source:HGNC Symbol;Acc:HGNC:5286] | 15580 | 0.000 | -0.3733 | No |
| 14 | HTR3E | 5-hydroxytryptamine receptor 3E [Source:HGNC Symbol;Acc:HGNC:24005] | 15589 | 0.000 | -0.3735 | No |
| 15 | HTR3C | 5-hydroxytryptamine receptor 3C [Source:HGNC Symbol;Acc:HGNC:24003] | 15590 | 0.000 | -0.3735 | No |
| 16 | HTR3D | 5-hydroxytryptamine receptor 3D [Source:HGNC Symbol;Acc:HGNC:24004] | 15591 | 0.000 | -0.3735 | No |
| 17 | HTR3A | 5-hydroxytryptamine receptor 3A [Source:HGNC Symbol;Acc:HGNC:5297] | 15592 | 0.000 | -0.3735 | No |
| 18 | HTR3B | 5-hydroxytryptamine receptor 3B [Source:HGNC Symbol;Acc:HGNC:5298] | 15593 | 0.000 | -0.3735 | No |
| 19 | HTR5A | 5-hydroxytryptamine receptor 5A [Source:HGNC Symbol;Acc:HGNC:5300] | 15604 | 0.000 | -0.3738 | No |
| 20 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17724 | 0.000 | -0.4310 | No |
| 21 | CHRM1 | cholinergic receptor muscarinic 1 [Source:HGNC Symbol;Acc:HGNC:1950] | 17726 | 0.000 | -0.4310 | No |
| 22 | CHRM5 | cholinergic receptor muscarinic 5 [Source:HGNC Symbol;Acc:HGNC:1954] | 17727 | 0.000 | -0.4310 | No |
| 23 | DRD4 | dopamine receptor D4 [Source:HGNC Symbol;Acc:HGNC:3025] | 18361 | 0.000 | -0.4481 | No |
| 24 | OR10J5 | olfactory receptor family 10 subfamily J member 5 [Source:HGNC Symbol;Acc:HGNC:14993] | 25402 | 0.000 | -0.6381 | No |
| 25 | OR10H1 | olfactory receptor family 10 subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:8172] | 25425 | 0.000 | -0.6387 | No |
| 26 | OR10H3 | olfactory receptor family 10 subfamily H member 3 [Source:HGNC Symbol;Acc:HGNC:8174] | 25426 | 0.000 | -0.6387 | No |
| 27 | OR10H2 | olfactory receptor family 10 subfamily H member 2 [Source:HGNC Symbol;Acc:HGNC:8173] | 25427 | 0.000 | -0.6387 | No |
| 28 | OR10H5 | olfactory receptor family 10 subfamily H member 5 [Source:HGNC Symbol;Acc:HGNC:15389] | 25428 | 0.000 | -0.6387 | No |
| 29 | OR10H4 | olfactory receptor family 10 subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:15388] | 25429 | 0.000 | -0.6387 | No |
| 30 | OR11H4 | olfactory receptor family 11 subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:15347] | 25650 | 0.000 | -0.6446 | No |
| 31 | OR11H7 | olfactory receptor family 11 subfamily H member 7 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:15350] | 25659 | 0.000 | -0.6448 | No |
| 32 | HRH3 | histamine receptor H3 [Source:HGNC Symbol;Acc:HGNC:5184] | 26414 | 0.000 | -0.6652 | No |
| 33 | HRH2 | histamine receptor H2 [Source:HGNC Symbol;Acc:HGNC:5183] | 26416 | 0.000 | -0.6652 | No |
| 34 | HRH4 | histamine receptor H4 [Source:HGNC Symbol;Acc:HGNC:17383] | 26419 | 0.000 | -0.6653 | No |
| 35 | OR10J6P | olfactory receptor family 10 subfamily J member 6 pseudogene [Source:HGNC Symbol;Acc:HGNC:14994] | 26707 | 0.000 | -0.6730 | No |
| 36 | HTR2A | 5-hydroxytryptamine receptor 2A [Source:HGNC Symbol;Acc:HGNC:5293] | 27565 | -0.068 | -0.6867 | Yes |
| 37 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 27834 | -0.101 | -0.6800 | Yes |
| 38 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 35594 | -2.154 | -0.5906 | Yes |
| 39 | HTR1B | 5-hydroxytryptamine receptor 1B [Source:HGNC Symbol;Acc:HGNC:5287] | 37065 | -4.547 | 0.0007 | Yes |
