Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GOBP_SYNAPTONEMAL_COMPLEX_ORGANIZATION |
| Enrichment Score (ES) | -0.9111079 |
| Normalized Enrichment Score (NES) | -1.5660529 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0943933 |
| FWER p-Value | 0.806 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | UBE2B | ubiquitin conjugating enzyme E2 B [Source:HGNC Symbol;Acc:HGNC:12473] | 6332 | 0.005 | -0.1705 | No |
| 2 | STAG3 | stromal antigen 3 [Source:HGNC Symbol;Acc:HGNC:11356] | 7829 | 0.000 | -0.2109 | No |
| 3 | RAD21L1 | RAD21 cohesin complex component like 1 [Source:HGNC Symbol;Acc:HGNC:16271] | 8048 | 0.000 | -0.2168 | No |
| 4 | C1orf146 | chromosome 1 open reading frame 146 [Source:HGNC Symbol;Acc:HGNC:24032] | 10120 | 0.000 | -0.2726 | No |
| 5 | MEIOC | meiosis specific with coiled-coil domain [Source:HGNC Symbol;Acc:HGNC:26670] | 10760 | 0.000 | -0.2899 | No |
| 6 | REC8 | REC8 meiotic recombination protein [Source:HGNC Symbol;Acc:HGNC:16879] | 13643 | 0.000 | -0.3676 | No |
| 7 | TEX11 | testis expressed 11 [Source:HGNC Symbol;Acc:HGNC:11733] | 15151 | 0.000 | -0.4083 | No |
| 8 | TEX12 | testis expressed 12 [Source:HGNC Symbol;Acc:HGNC:11734] | 15152 | 0.000 | -0.4083 | No |
| 9 | SYCE3 | synaptonemal complex central element protein 3 [Source:HGNC Symbol;Acc:HGNC:35245] | 16918 | 0.000 | -0.4559 | No |
| 10 | SYCE1 | synaptonemal complex central element protein 1 [Source:HGNC Symbol;Acc:HGNC:28852] | 16919 | 0.000 | -0.4559 | No |
| 11 | SYCP2 | synaptonemal complex protein 2 [Source:HGNC Symbol;Acc:HGNC:11490] | 17750 | 0.000 | -0.4783 | No |
| 12 | SYCP1 | synaptonemal complex protein 1 [Source:HGNC Symbol;Acc:HGNC:11487] | 17751 | 0.000 | -0.4783 | No |
| 13 | P3H4 | prolyl 3-hydroxylase family member 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:16946] | 18444 | 0.000 | -0.4970 | No |
| 14 | SPO11 | SPO11 initiator of meiotic double stranded breaks [Source:HGNC Symbol;Acc:HGNC:11250] | 19312 | 0.000 | -0.5204 | No |
| 15 | SYCE1L | synaptonemal complex central element protein 1 like [Source:HGNC Symbol;Acc:HGNC:37236] | 22452 | 0.000 | -0.6050 | No |
| 16 | BAG6 | BAG cochaperone 6 [Source:HGNC Symbol;Acc:HGNC:13919] | 27312 | -0.037 | -0.7338 | No |
| 17 | HORMAD1 | HORMA domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25245] | 28939 | -0.245 | -0.7623 | No |
| 18 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 30731 | -0.511 | -0.7787 | Yes |
| 19 | RAD21 | RAD21 cohesin complex component [Source:HGNC Symbol;Acc:HGNC:9811] | 35640 | -2.191 | -0.7741 | Yes |
| 20 | MLH3 | mutL homolog 3 [Source:HGNC Symbol;Acc:HGNC:7128] | 35679 | -2.218 | -0.6365 | Yes |
| 21 | AGO4 | argonaute RISC component 4 [Source:HGNC Symbol;Acc:HGNC:18424] | 35838 | -2.349 | -0.4940 | Yes |
| 22 | HSPA2 | heat shock protein family A (Hsp70) member 2 [Source:HGNC Symbol;Acc:HGNC:5235] | 36143 | -2.659 | -0.3360 | Yes |
| 23 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 36261 | -2.777 | -0.1656 | Yes |
| 24 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36483 | -3.006 | 0.0164 | Yes |
