Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | CAHOY_OLIGODENDROCUTIC |
| Enrichment Score (ES) | -0.6529414 |
| Normalized Enrichment Score (NES) | -1.3465323 |
| Nominal p-value | 0.021300448 |
| FDR q-value | 0.15346669 |
| FWER p-Value | 0.859 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DOCK10 | dedicator of cytokinesis 10 [Source:HGNC Symbol;Acc:HGNC:23479] | 421 | 2.534 | 0.0166 | No |
| 2 | EFHD2 | EF-hand domain family member D2 [Source:HGNC Symbol;Acc:HGNC:28670] | 765 | 1.873 | 0.0280 | No |
| 3 | ADGRL2 | adhesion G protein-coupled receptor L2 [Source:HGNC Symbol;Acc:HGNC:18582] | 916 | 1.645 | 0.0420 | No |
| 4 | ZNF276 | zinc finger protein 276 [Source:HGNC Symbol;Acc:HGNC:23330] | 1375 | 1.262 | 0.0436 | No |
| 5 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 1431 | 1.222 | 0.0556 | No |
| 6 | EVI2A | ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499] | 1671 | 1.072 | 0.0610 | No |
| 7 | USP16 | ubiquitin specific peptidase 16 [Source:HGNC Symbol;Acc:HGNC:12614] | 2226 | 0.826 | 0.0551 | No |
| 8 | HIP1R | huntingtin interacting protein 1 related [Source:HGNC Symbol;Acc:HGNC:18415] | 2984 | 0.583 | 0.0410 | No |
| 9 | AHR | aryl hydrocarbon receptor [Source:HGNC Symbol;Acc:HGNC:348] | 3649 | 0.429 | 0.0278 | No |
| 10 | MYRF | myelin regulatory factor [Source:HGNC Symbol;Acc:HGNC:1181] | 3781 | 0.406 | 0.0288 | No |
| 11 | POP4 | POP4 homolog, ribonuclease P/MRP subunit [Source:HGNC Symbol;Acc:HGNC:30081] | 3919 | 0.375 | 0.0292 | No |
| 12 | GAL3ST1 | galactose-3-O-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:24240] | 4182 | 0.326 | 0.0257 | No |
| 13 | NINJ2 | ninjurin 2 [Source:HGNC Symbol;Acc:HGNC:7825] | 4590 | 0.254 | 0.0175 | No |
| 14 | FAM89A | family with sequence similarity 89 member A [Source:HGNC Symbol;Acc:HGNC:25057] | 5489 | 0.122 | -0.0054 | No |
| 15 | COL20A1 | collagen type XX alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:14670] | 5974 | 0.057 | -0.0179 | No |
| 16 | BCAS1 | brain enriched myelin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:974] | 6271 | 0.011 | -0.0258 | No |
| 17 | NCMAP | non-compact myelin associated protein [Source:HGNC Symbol;Acc:HGNC:29332] | 6904 | 0.000 | -0.0428 | No |
| 18 | CNTNAP2 | contactin associated protein 2 [Source:HGNC Symbol;Acc:HGNC:13830] | 7380 | 0.000 | -0.0557 | No |
| 19 | FA2H | fatty acid 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:21197] | 7626 | 0.000 | -0.0623 | No |
| 20 | FBP1 | fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606] | 8224 | 0.000 | -0.0785 | No |
| 21 | MAP6D1 | MAP6 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25753] | 8405 | 0.000 | -0.0833 | No |
| 22 | SOX10 | SRY-box transcription factor 10 [Source:HGNC Symbol;Acc:HGNC:11190] | 8769 | 0.000 | -0.0931 | No |
| 23 | PLLP | plasmolipin [Source:HGNC Symbol;Acc:HGNC:18553] | 10054 | 0.000 | -0.1278 | No |
| 24 | TSPAN2 | tetraspanin 2 [Source:HGNC Symbol;Acc:HGNC:20659] | 11476 | 0.000 | -0.1663 | No |
| 25 | ATP10B | ATPase phospholipid transporting 10B (putative) [Source:HGNC Symbol;Acc:HGNC:13543] | 12112 | 0.000 | -0.1834 | No |
| 26 | TENM1 | teneurin transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:8117] | 12726 | 0.000 | -0.2000 | No |
| 27 | CDR2L | cerebellar degeneration related protein 2 like [Source:HGNC Symbol;Acc:HGNC:29999] | 13036 | 0.000 | -0.2083 | No |
| 28 | DMRTA1 | DMRT like family A1 [Source:HGNC Symbol;Acc:HGNC:13826] | 14849 | 0.000 | -0.2573 | No |
| 29 | GJE1 | gap junction protein epsilon 1 [Source:HGNC Symbol;Acc:HGNC:33251] | 15431 | 0.000 | -0.2730 | No |
| 30 | BCR | BCR activator of RhoGEF and GTPase [Source:HGNC Symbol;Acc:HGNC:1014] | 15521 | 0.000 | -0.2754 | No |
| 31 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 15994 | 0.000 | -0.2882 | No |
| 32 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16313 | 0.000 | -0.2968 | No |
| 33 | GPR17 | G protein-coupled receptor 17 [Source:HGNC Symbol;Acc:HGNC:4471] | 17382 | 0.000 | -0.3257 | No |
| 34 | SEMA3D | semaphorin 3D [Source:HGNC Symbol;Acc:HGNC:10726] | 17757 | 0.000 | -0.3358 | No |
| 35 | BFSP2 | beaded filament structural protein 2 [Source:HGNC Symbol;Acc:HGNC:1041] | 18088 | 0.000 | -0.3447 | No |
| 36 | FEZF2 | FEZ family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:13506] | 18518 | 0.000 | -0.3563 | No |
| 37 | AGAP11 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 11 [Source:HGNC Symbol;Acc:HGNC:29421] | 19517 | 0.000 | -0.3833 | No |
| 38 | DUSP15 | dual specificity phosphatase 15 [Source:HGNC Symbol;Acc:HGNC:16236] | 20453 | 0.000 | -0.4086 | No |
| 39 | GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 [Source:HGNC Symbol;Acc:HGNC:30488] | 20559 | 0.000 | -0.4114 | No |
| 40 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 21132 | 0.000 | -0.4269 | No |
| 41 | ZNF536 | zinc finger protein 536 [Source:HGNC Symbol;Acc:HGNC:29025] | 21603 | 0.000 | -0.4396 | No |
| 42 | LHFPL6 | LHFPL tetraspan subfamily member 6 [Source:HGNC Symbol;Acc:HGNC:6586] | 22445 | 0.000 | -0.4623 | No |
| 43 | CCN2 | cellular communication network factor 2 [Source:HGNC Symbol;Acc:HGNC:2500] | 22713 | 0.000 | -0.4695 | No |
| 44 | RBM11 | RNA binding motif protein 11 [Source:HGNC Symbol;Acc:HGNC:9897] | 23352 | 0.000 | -0.4868 | No |
| 45 | CRYM | crystallin mu [Source:HGNC Symbol;Acc:HGNC:2418] | 24135 | 0.000 | -0.5079 | No |
| 46 | UGT8 | UDP glycosyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:12555] | 24578 | 0.000 | -0.5199 | No |
| 47 | FIGN | fidgetin, microtubule severing factor [Source:HGNC Symbol;Acc:HGNC:13285] | 25711 | 0.000 | -0.5505 | No |
| 48 | SOX8 | SRY-box transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:11203] | 25780 | 0.000 | -0.5523 | No |
| 49 | PRKCQ | protein kinase C theta [Source:HGNC Symbol;Acc:HGNC:9410] | 27528 | -0.063 | -0.5988 | No |
| 50 | NGRN | neugrin, neurite outgrowth associated [Source:HGNC Symbol;Acc:HGNC:18077] | 27776 | -0.092 | -0.6045 | No |
| 51 | PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:9581] | 28102 | -0.134 | -0.6118 | No |
| 52 | ERBB3 | erb-b2 receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3431] | 28147 | -0.139 | -0.6115 | No |
| 53 | CSDC2 | cold shock domain containing C2 [Source:HGNC Symbol;Acc:HGNC:30359] | 28266 | -0.154 | -0.6130 | No |
| 54 | FBXO7 | F-box protein 7 [Source:HGNC Symbol;Acc:HGNC:13586] | 28298 | -0.157 | -0.6121 | No |
| 55 | CLN8 | CLN8 transmembrane ER and ERGIC protein [Source:HGNC Symbol;Acc:HGNC:2079] | 28579 | -0.197 | -0.6175 | No |
| 56 | EPN2 | epsin 2 [Source:HGNC Symbol;Acc:HGNC:18639] | 28635 | -0.204 | -0.6167 | No |
| 57 | PUS7 | pseudouridine synthase 7 [Source:HGNC Symbol;Acc:HGNC:26033] | 28689 | -0.212 | -0.6158 | No |
| 58 | BACE1 | beta-secretase 1 [Source:HGNC Symbol;Acc:HGNC:933] | 28690 | -0.212 | -0.6135 | No |
| 59 | CPOX | coproporphyrinogen oxidase [Source:HGNC Symbol;Acc:HGNC:2321] | 29555 | -0.332 | -0.6332 | No |
| 60 | TLCD3A | TLC domain containing 3A [Source:HGNC Symbol;Acc:HGNC:29646] | 29975 | -0.393 | -0.6401 | No |
| 61 | WIPF1 | WAS/WASL interacting protein family member 1 [Source:HGNC Symbol;Acc:HGNC:12736] | 30261 | -0.437 | -0.6430 | No |
| 62 | RNASEH2B | ribonuclease H2 subunit B [Source:HGNC Symbol;Acc:HGNC:25671] | 30542 | -0.478 | -0.6453 | Yes |
| 63 | SRPK3 | SRSF protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:11402] | 30684 | -0.503 | -0.6436 | Yes |
| 64 | GNG8 | G protein subunit gamma 8 [Source:HGNC Symbol;Acc:HGNC:19664] | 30935 | -0.546 | -0.6443 | Yes |
| 65 | PHLDB1 | pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697] | 30943 | -0.547 | -0.6385 | Yes |
| 66 | NR2C1 | nuclear receptor subfamily 2 group C member 1 [Source:HGNC Symbol;Acc:HGNC:7971] | 31225 | -0.594 | -0.6395 | Yes |
| 67 | GAB3 | GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515] | 31433 | -0.635 | -0.6381 | Yes |
| 68 | SIRT2 | sirtuin 2 [Source:HGNC Symbol;Acc:HGNC:10886] | 31626 | -0.676 | -0.6359 | Yes |
| 69 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 32259 | -0.821 | -0.6439 | Yes |
| 70 | DRC3 | dynein regulatory complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25384] | 32281 | -0.827 | -0.6353 | Yes |
| 71 | AP5Z1 | adaptor related protein complex 5 subunit zeta 1 [Source:HGNC Symbol;Acc:HGNC:22197] | 32341 | -0.842 | -0.6276 | Yes |
| 72 | PKIG | cAMP-dependent protein kinase inhibitor gamma [Source:HGNC Symbol;Acc:HGNC:9019] | 32739 | -0.945 | -0.6279 | Yes |
| 73 | SPEG | striated muscle enriched protein kinase [Source:HGNC Symbol;Acc:HGNC:16901] | 32861 | -0.977 | -0.6204 | Yes |
| 74 | RNF122 | ring finger protein 122 [Source:HGNC Symbol;Acc:HGNC:21147] | 32925 | -0.996 | -0.6112 | Yes |
| 75 | CRIP2 | cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361] | 33008 | -1.019 | -0.6021 | Yes |
| 76 | KCTD1 | potassium channel tetramerization domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18249] | 33251 | -1.090 | -0.5967 | Yes |
| 77 | DUSP19 | dual specificity phosphatase 19 [Source:HGNC Symbol;Acc:HGNC:18894] | 33374 | -1.130 | -0.5875 | Yes |
| 78 | SEMA5A | semaphorin 5A [Source:HGNC Symbol;Acc:HGNC:10736] | 33412 | -1.141 | -0.5759 | Yes |
| 79 | SERINC5 | serine incorporator 5 [Source:HGNC Symbol;Acc:HGNC:18825] | 33462 | -1.157 | -0.5645 | Yes |
| 80 | RTKN | rhotekin [Source:HGNC Symbol;Acc:HGNC:10466] | 34173 | -1.399 | -0.5682 | Yes |
| 81 | DOCK7 | dedicator of cytokinesis 7 [Source:HGNC Symbol;Acc:HGNC:19190] | 34177 | -1.400 | -0.5529 | Yes |
| 82 | G2E3 | G2/M-phase specific E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:20338] | 34441 | -1.517 | -0.5432 | Yes |
| 83 | PPP1R21 | protein phosphatase 1 regulatory subunit 21 [Source:HGNC Symbol;Acc:HGNC:30595] | 34678 | -1.618 | -0.5318 | Yes |
| 84 | DCPS | decapping enzyme, scavenger [Source:HGNC Symbol;Acc:HGNC:29812] | 34912 | -1.726 | -0.5190 | Yes |
| 85 | RCBTB1 | RCC1 and BTB domain containing protein 1 [Source:HGNC Symbol;Acc:HGNC:18243] | 35356 | -1.984 | -0.5091 | Yes |
| 86 | IFFO1 | intermediate filament family orphan 1 [Source:HGNC Symbol;Acc:HGNC:24970] | 36097 | -2.607 | -0.5004 | Yes |
| 87 | KIAA1958 | KIAA1958 [Source:HGNC Symbol;Acc:HGNC:23427] | 36120 | -2.628 | -0.4720 | Yes |
| 88 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 36365 | -2.887 | -0.4467 | Yes |
| 89 | CLYBL | citramalyl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:18355] | 36431 | -2.964 | -0.4158 | Yes |
| 90 | PLXNB3 | plexin B3 [Source:HGNC Symbol;Acc:HGNC:9105] | 36487 | -3.009 | -0.3841 | Yes |
| 91 | MAP3K15 | mitogen-activated protein kinase kinase kinase 15 [Source:HGNC Symbol;Acc:HGNC:31689] | 36498 | -3.021 | -0.3510 | Yes |
| 92 | NRP1 | neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004] | 36578 | -3.130 | -0.3186 | Yes |
| 93 | ABHD8 | abhydrolase domain containing 8 [Source:HGNC Symbol;Acc:HGNC:23759] | 36705 | -3.352 | -0.2851 | Yes |
| 94 | CILK1 | ciliogenesis associated kinase 1 [Source:HGNC Symbol;Acc:HGNC:21219] | 36712 | -3.368 | -0.2481 | Yes |
| 95 | LCORL | ligand dependent nuclear receptor corepressor like [Source:HGNC Symbol;Acc:HGNC:30776] | 36721 | -3.387 | -0.2109 | Yes |
| 96 | ELOVL6 | ELOVL fatty acid elongase 6 [Source:HGNC Symbol;Acc:HGNC:15829] | 36826 | -3.587 | -0.1742 | Yes |
| 97 | PRKAG2 | protein kinase AMP-activated non-catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:9386] | 36839 | -3.618 | -0.1346 | Yes |
| 98 | P4HA2 | prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8547] | 36994 | -4.109 | -0.0934 | Yes |
| 99 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 37033 | -4.339 | -0.0466 | Yes |
| 100 | LRRC75A | leucine rich repeat containing 75A [Source:HGNC Symbol;Acc:HGNC:32403] | 37038 | -4.360 | 0.0014 | Yes |
