Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | CSR_EARLY_UP.V1_DN |
| Enrichment Score (ES) | -0.6432591 |
| Normalized Enrichment Score (NES) | -1.3741791 |
| Nominal p-value | 0.0077348067 |
| FDR q-value | 0.12888934 |
| FWER p-Value | 0.668 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 23 | 4.827 | 0.0393 | No |
| 2 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 132 | 3.896 | 0.0687 | No |
| 3 | TRIM56 | tripartite motif containing 56 [Source:HGNC Symbol;Acc:HGNC:19028] | 636 | 2.097 | 0.0724 | No |
| 4 | MINDY1 | MINDY lysine 48 deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:25648] | 788 | 1.831 | 0.0835 | No |
| 5 | IP6K2 | inositol hexakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:17313] | 834 | 1.745 | 0.0967 | No |
| 6 | ELMOD2 | ELMO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28111] | 2330 | 0.791 | 0.0628 | No |
| 7 | DENND11 | DENN domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29472] | 2774 | 0.645 | 0.0562 | No |
| 8 | TENT5C | terminal nucleotidyltransferase 5C [Source:HGNC Symbol;Acc:HGNC:24712] | 2805 | 0.635 | 0.0606 | No |
| 9 | LRIG2 | leucine rich repeats and immunoglobulin like domains 2 [Source:HGNC Symbol;Acc:HGNC:20889] | 2896 | 0.609 | 0.0632 | No |
| 10 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 3205 | 0.529 | 0.0593 | No |
| 11 | GRHL1 | grainyhead like transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:17923] | 3763 | 0.409 | 0.0476 | No |
| 12 | FBXO38 | F-box protein 38 [Source:HGNC Symbol;Acc:HGNC:28844] | 4468 | 0.275 | 0.0308 | No |
| 13 | FBXO25 | F-box protein 25 [Source:HGNC Symbol;Acc:HGNC:13596] | 4681 | 0.239 | 0.0271 | No |
| 14 | DHRS3 | dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693] | 4705 | 0.236 | 0.0284 | No |
| 15 | NR1H3 | nuclear receptor subfamily 1 group H member 3 [Source:HGNC Symbol;Acc:HGNC:7966] | 4743 | 0.229 | 0.0293 | No |
| 16 | PLCD1 | phospholipase C delta 1 [Source:HGNC Symbol;Acc:HGNC:9060] | 4830 | 0.216 | 0.0288 | No |
| 17 | RNF20 | ring finger protein 20 [Source:HGNC Symbol;Acc:HGNC:10062] | 4904 | 0.207 | 0.0285 | No |
| 18 | DXO | decapping exoribonuclease [Source:HGNC Symbol;Acc:HGNC:2992] | 5181 | 0.165 | 0.0224 | No |
| 19 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 5200 | 0.161 | 0.0233 | No |
| 20 | STX16 | syntaxin 16 [Source:HGNC Symbol;Acc:HGNC:11431] | 5344 | 0.141 | 0.0206 | No |
| 21 | ZNF33A | zinc finger protein 33A [Source:HGNC Symbol;Acc:HGNC:13096] | 5913 | 0.066 | 0.0057 | No |
| 22 | ZFP64 | ZFP64 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:15940] | 5958 | 0.060 | 0.0050 | No |
| 23 | ABCC10 | ATP binding cassette subfamily C member 10 [Source:HGNC Symbol;Acc:HGNC:52] | 5984 | 0.056 | 0.0048 | No |
| 24 | ZFYVE1 | zinc finger FYVE-type containing 1 [Source:HGNC Symbol;Acc:HGNC:13180] | 5986 | 0.056 | 0.0053 | No |
| 25 | TAF15 | TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547] | 6314 | 0.008 | -0.0035 | No |
| 26 | RAPGEF3 | Rap guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:16629] | 6691 | 0.000 | -0.0137 | No |
| 27 | DAAM2 | dishevelled associated activator of morphogenesis 2 [Source:HGNC Symbol;Acc:HGNC:18143] | 6952 | 0.000 | -0.0207 | No |
| 28 | ASPA | aspartoacylase [Source:HGNC Symbol;Acc:HGNC:756] | 7776 | 0.000 | -0.0430 | No |
| 29 | PMS2P1 | PMS1 homolog 2, mismatch repair system component pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9123] | 7910 | 0.000 | -0.0466 | No |
| 30 | TDRD6 | tudor domain containing 6 [Source:HGNC Symbol;Acc:HGNC:21339] | 9061 | 0.000 | -0.0777 | No |
| 31 | NDNF | neuron derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:26256] | 9503 | 0.000 | -0.0896 | No |
| 32 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 10312 | 0.000 | -0.1115 | No |
| 33 | GFRA1 | GDNF family receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4243] | 11195 | 0.000 | -0.1353 | No |
| 34 | ERAP2 | endoplasmic reticulum aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:29499] | 11443 | 0.000 | -0.1420 | No |
| 35 | GSDMB | gasdermin B [Source:HGNC Symbol;Acc:HGNC:23690] | 13154 | 0.000 | -0.1883 | No |
| 36 | CDRT4 | CMT1A duplicated region transcript 4 [Source:HGNC Symbol;Acc:HGNC:14383] | 13317 | 0.000 | -0.1927 | No |
| 37 | NYNRIN | NYN domain and retroviral integrase containing [Source:HGNC Symbol;Acc:HGNC:20165] | 13897 | 0.000 | -0.2083 | No |
| 38 | HOXA10 | homeobox A10 [Source:HGNC Symbol;Acc:HGNC:5100] | 14236 | 0.000 | -0.2175 | No |
| 39 | STOX1 | storkhead box 1 [Source:HGNC Symbol;Acc:HGNC:23508] | 15849 | 0.000 | -0.2611 | No |
| 40 | MAB21L1 | mab-21 like 1 [Source:HGNC Symbol;Acc:HGNC:6757] | 15857 | 0.000 | -0.2613 | No |
| 41 | SLC7A14 | solute carrier family 7 member 14 [Source:HGNC Symbol;Acc:HGNC:29326] | 16220 | 0.000 | -0.2711 | No |
| 42 | SLC9A7 | solute carrier family 9 member A7 [Source:HGNC Symbol;Acc:HGNC:17123] | 17462 | 0.000 | -0.3046 | No |
| 43 | PAPLN | papilin, proteoglycan like sulfated glycoprotein [Source:HGNC Symbol;Acc:HGNC:19262] | 17794 | 0.000 | -0.3136 | No |
| 44 | C14orf132 | chromosome 14 open reading frame 132 [Source:HGNC Symbol;Acc:HGNC:20346] | 17812 | 0.000 | -0.3141 | No |
| 45 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18322 | 0.000 | -0.3278 | No |
| 46 | SULF1 | sulfatase 1 [Source:HGNC Symbol;Acc:HGNC:20391] | 21559 | 0.000 | -0.4154 | No |
| 47 | ZNF337 | zinc finger protein 337 [Source:HGNC Symbol;Acc:HGNC:15809] | 22245 | 0.000 | -0.4339 | No |
| 48 | ZNF302 | zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848] | 22289 | 0.000 | -0.4351 | No |
| 49 | CYP2R1 | cytochrome P450 family 2 subfamily R member 1 [Source:HGNC Symbol;Acc:HGNC:20580] | 22487 | 0.000 | -0.4404 | No |
| 50 | CAVIN2 | caveolae associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10690] | 23389 | 0.000 | -0.4648 | No |
| 51 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 25326 | 0.000 | -0.5171 | No |
| 52 | SNPH | syntaphilin [Source:HGNC Symbol;Acc:HGNC:15931] | 25484 | 0.000 | -0.5214 | No |
| 53 | NSUN5P2 | NSUN5 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:16609] | 25675 | 0.000 | -0.5265 | No |
| 54 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 26886 | 0.000 | -0.5593 | No |
| 55 | TFAP2A | transcription factor AP-2 alpha [Source:HGNC Symbol;Acc:HGNC:11742] | 27317 | -0.038 | -0.5706 | No |
| 56 | ZNF585B | zinc finger protein 585B [Source:HGNC Symbol;Acc:HGNC:30948] | 27457 | -0.056 | -0.5739 | No |
| 57 | EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3 [Source:HGNC Symbol;Acc:HGNC:3290] | 27541 | -0.065 | -0.5756 | No |
| 58 | CROCCP2 | CROCC pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:28170] | 27593 | -0.069 | -0.5764 | No |
| 59 | GDF5 | growth differentiation factor 5 [Source:HGNC Symbol;Acc:HGNC:4220] | 27813 | -0.098 | -0.5815 | No |
| 60 | RABGAP1 | RAB GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:17155] | 27987 | -0.121 | -0.5852 | No |
| 61 | SAG | S-antigen visual arrestin [Source:HGNC Symbol;Acc:HGNC:10521] | 28144 | -0.139 | -0.5883 | No |
| 62 | CC2D1A | coiled-coil and C2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:30237] | 28411 | -0.173 | -0.5940 | No |
| 63 | GTPBP8 | GTP binding protein 8 (putative) [Source:HGNC Symbol;Acc:HGNC:25007] | 28749 | -0.220 | -0.6013 | No |
| 64 | PHIP | pleckstrin homology domain interacting protein [Source:HGNC Symbol;Acc:HGNC:15673] | 28889 | -0.240 | -0.6031 | No |
| 65 | TCAIM | T cell activation inhibitor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25241] | 29152 | -0.276 | -0.6079 | No |
| 66 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 29695 | -0.353 | -0.6196 | No |
| 67 | PDE5A | phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784] | 29755 | -0.360 | -0.6183 | No |
| 68 | SLC25A46 | solute carrier family 25 member 46 [Source:HGNC Symbol;Acc:HGNC:25198] | 29825 | -0.372 | -0.6170 | No |
| 69 | ZNF500 | zinc finger protein 500 [Source:HGNC Symbol;Acc:HGNC:23716] | 30424 | -0.458 | -0.6294 | No |
| 70 | LTN1 | listerin E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:13082] | 30689 | -0.503 | -0.6324 | No |
| 71 | HEBP2 | heme binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15716] | 30705 | -0.506 | -0.6286 | No |
| 72 | PRRT2 | proline rich transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:30500] | 30921 | -0.544 | -0.6299 | No |
| 73 | ARL4D | ADP ribosylation factor like GTPase 4D [Source:HGNC Symbol;Acc:HGNC:656] | 30959 | -0.550 | -0.6264 | No |
| 74 | PAN2 | poly(A) specific ribonuclease subunit PAN2 [Source:HGNC Symbol;Acc:HGNC:20074] | 31114 | -0.575 | -0.6258 | No |
| 75 | UBN2 | ubinuclein 2 [Source:HGNC Symbol;Acc:HGNC:21931] | 31642 | -0.679 | -0.6344 | No |
| 76 | LRRK2 | leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618] | 31970 | -0.754 | -0.6370 | Yes |
| 77 | SIX1 | SIX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10887] | 32062 | -0.777 | -0.6330 | Yes |
| 78 | MOSPD2 | motile sperm domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28381] | 32258 | -0.821 | -0.6315 | Yes |
| 79 | PEX6 | peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859] | 32260 | -0.821 | -0.6248 | Yes |
| 80 | USP33 | ubiquitin specific peptidase 33 [Source:HGNC Symbol;Acc:HGNC:20059] | 32516 | -0.882 | -0.6244 | Yes |
| 81 | ZNF467 | zinc finger protein 467 [Source:HGNC Symbol;Acc:HGNC:23154] | 32936 | -0.998 | -0.6274 | Yes |
| 82 | NATD1 | N-acetyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30770] | 33113 | -1.049 | -0.6235 | Yes |
| 83 | ACBD4 | acyl-CoA binding domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23337] | 33151 | -1.061 | -0.6157 | Yes |
| 84 | MSRB1 | methionine sulfoxide reductase B1 [Source:HGNC Symbol;Acc:HGNC:14133] | 33165 | -1.064 | -0.6073 | Yes |
| 85 | KBTBD6 | kelch repeat and BTB domain containing 6 [Source:HGNC Symbol;Acc:HGNC:25340] | 33950 | -1.323 | -0.6175 | Yes |
| 86 | DCP1B | decapping mRNA 1B [Source:HGNC Symbol;Acc:HGNC:24451] | 34223 | -1.421 | -0.6131 | Yes |
| 87 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 34311 | -1.461 | -0.6034 | Yes |
| 88 | ATF7IP | activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092] | 34362 | -1.484 | -0.5925 | Yes |
| 89 | ALDH3B2 | aldehyde dehydrogenase 3 family member B2 [Source:HGNC Symbol;Acc:HGNC:411] | 34374 | -1.490 | -0.5804 | Yes |
| 90 | YEATS2 | YEATS domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25489] | 34384 | -1.493 | -0.5683 | Yes |
| 91 | ALDH1L2 | aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777] | 34465 | -1.528 | -0.5578 | Yes |
| 92 | NMT2 | N-myristoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:7858] | 34622 | -1.592 | -0.5488 | Yes |
| 93 | ANKZF1 | ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:25527] | 34658 | -1.609 | -0.5365 | Yes |
| 94 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 34707 | -1.630 | -0.5243 | Yes |
| 95 | SIX5 | SIX homeobox 5 [Source:HGNC Symbol;Acc:HGNC:10891] | 34754 | -1.649 | -0.5119 | Yes |
| 96 | ARRDC3 | arrestin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29263] | 34773 | -1.659 | -0.4986 | Yes |
| 97 | SLC16A7 | solute carrier family 16 member 7 [Source:HGNC Symbol;Acc:HGNC:10928] | 34780 | -1.661 | -0.4850 | Yes |
| 98 | ADAMTSL4 | ADAMTS like 4 [Source:HGNC Symbol;Acc:HGNC:19706] | 34854 | -1.696 | -0.4730 | Yes |
| 99 | NDUFAF7 | NADH:ubiquinone oxidoreductase complex assembly factor 7 [Source:HGNC Symbol;Acc:HGNC:28816] | 34967 | -1.754 | -0.4615 | Yes |
| 100 | UFSP2 | UFM1 specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:25640] | 34971 | -1.757 | -0.4470 | Yes |
| 101 | HBP1 | HMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200] | 34992 | -1.766 | -0.4329 | Yes |
| 102 | DDX17 | DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:2740] | 35005 | -1.770 | -0.4186 | Yes |
| 103 | BRD8 | bromodomain containing 8 [Source:HGNC Symbol;Acc:HGNC:19874] | 35047 | -1.793 | -0.4049 | Yes |
| 104 | POLL | DNA polymerase lambda [Source:HGNC Symbol;Acc:HGNC:9184] | 35097 | -1.824 | -0.3911 | Yes |
| 105 | NPHP3 | nephrocystin 3 [Source:HGNC Symbol;Acc:HGNC:7907] | 35184 | -1.872 | -0.3779 | Yes |
| 106 | MPPE1 | metallophosphoesterase 1 [Source:HGNC Symbol;Acc:HGNC:15988] | 35517 | -2.092 | -0.3696 | Yes |
| 107 | ACCS | 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) [Source:HGNC Symbol;Acc:HGNC:23989] | 35545 | -2.110 | -0.3528 | Yes |
| 108 | ZNF226 | zinc finger protein 226 [Source:HGNC Symbol;Acc:HGNC:13019] | 35550 | -2.114 | -0.3355 | Yes |
| 109 | OTUD1 | OTU deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:27346] | 35565 | -2.127 | -0.3182 | Yes |
| 110 | CDKN1B | cyclin dependent kinase inhibitor 1B [Source:HGNC Symbol;Acc:HGNC:1785] | 35569 | -2.133 | -0.3006 | Yes |
| 111 | AKIP1 | A-kinase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:1170] | 35592 | -2.152 | -0.2834 | Yes |
| 112 | CIRBP | cold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:1982] | 35606 | -2.161 | -0.2659 | Yes |
| 113 | LRIG3 | leucine rich repeats and immunoglobulin like domains 3 [Source:HGNC Symbol;Acc:HGNC:30991] | 35626 | -2.178 | -0.2484 | Yes |
| 114 | AMT | aminomethyltransferase [Source:HGNC Symbol;Acc:HGNC:473] | 35689 | -2.223 | -0.2316 | Yes |
| 115 | ING4 | inhibitor of growth family member 4 [Source:HGNC Symbol;Acc:HGNC:19423] | 35705 | -2.238 | -0.2135 | Yes |
| 116 | LDB1 | LIM domain binding 1 [Source:HGNC Symbol;Acc:HGNC:6532] | 35854 | -2.364 | -0.1980 | Yes |
| 117 | FUT10 | fucosyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:19234] | 35877 | -2.387 | -0.1788 | Yes |
| 118 | CKB | creatine kinase B [Source:HGNC Symbol;Acc:HGNC:1991] | 35911 | -2.418 | -0.1597 | Yes |
| 119 | ACYP1 | acylphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:179] | 35939 | -2.447 | -0.1401 | Yes |
| 120 | ELMOD3 | ELMO domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26158] | 35941 | -2.450 | -0.1199 | Yes |
| 121 | ADM | adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259] | 36003 | -2.504 | -0.1008 | Yes |
| 122 | C2CD5 | C2 calcium dependent domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29062] | 36069 | -2.567 | -0.0813 | Yes |
| 123 | MRI1 | methylthioribose-1-phosphate isomerase 1 [Source:HGNC Symbol;Acc:HGNC:28469] | 36222 | -2.739 | -0.0628 | Yes |
| 124 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 36400 | -2.929 | -0.0433 | Yes |
| 125 | FZD2 | frizzled class receptor 2 [Source:HGNC Symbol;Acc:HGNC:4040] | 36723 | -3.389 | -0.0240 | Yes |
| 126 | WEE1 | WEE1 G2 checkpoint kinase [Source:HGNC Symbol;Acc:HGNC:12761] | 36989 | -4.089 | 0.0027 | Yes |
