Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | KRAS.KIDNEY_UP.V1_DN |
| Enrichment Score (ES) | 0.52619994 |
| Normalized Enrichment Score (NES) | 1.3877872 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07718973 |
| FWER p-Value | 0.202 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 6 | 4.960 | 0.0522 | Yes |
| 2 | PTGER2 | prostaglandin E receptor 2 [Source:HGNC Symbol;Acc:HGNC:9594] | 17 | 4.883 | 0.1034 | Yes |
| 3 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 31 | 4.755 | 0.1532 | Yes |
| 4 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 35 | 4.721 | 0.2029 | Yes |
| 5 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 48 | 4.592 | 0.2510 | Yes |
| 6 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 134 | 3.887 | 0.2897 | Yes |
| 7 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 202 | 3.471 | 0.3245 | Yes |
| 8 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 230 | 3.311 | 0.3587 | Yes |
| 9 | ETS1 | ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488] | 240 | 3.272 | 0.3930 | Yes |
| 10 | KCND1 | potassium voltage-gated channel subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:6237] | 317 | 2.937 | 0.4219 | Yes |
| 11 | SRC | SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283] | 333 | 2.867 | 0.4517 | Yes |
| 12 | ACTC1 | actin alpha cardiac muscle 1 [Source:HGNC Symbol;Acc:HGNC:143] | 443 | 2.498 | 0.4751 | Yes |
| 13 | EFHD1 | EF-hand domain family member D1 [Source:HGNC Symbol;Acc:HGNC:29556] | 701 | 1.978 | 0.4890 | Yes |
| 14 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 732 | 1.930 | 0.5086 | Yes |
| 15 | GPR35 | G protein-coupled receptor 35 [Source:HGNC Symbol;Acc:HGNC:4492] | 1392 | 1.249 | 0.5039 | Yes |
| 16 | IL23A | interleukin 23 subunit alpha [Source:HGNC Symbol;Acc:HGNC:15488] | 1606 | 1.114 | 0.5099 | Yes |
| 17 | HINFP | histone H4 transcription factor [Source:HGNC Symbol;Acc:HGNC:17850] | 1752 | 1.032 | 0.5169 | Yes |
| 18 | LIPE | lipase E, hormone sensitive type [Source:HGNC Symbol;Acc:HGNC:6621] | 1888 | 0.968 | 0.5234 | Yes |
| 19 | PDCD1 | programmed cell death 1 [Source:HGNC Symbol;Acc:HGNC:8760] | 2124 | 0.867 | 0.5262 | Yes |
| 20 | NES | nestin [Source:HGNC Symbol;Acc:HGNC:7756] | 2529 | 0.727 | 0.5229 | No |
| 21 | CLEC3B | C-type lectin domain family 3 member B [Source:HGNC Symbol;Acc:HGNC:11891] | 3004 | 0.577 | 0.5162 | No |
| 22 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 3205 | 0.529 | 0.5164 | No |
| 23 | TACR2 | tachykinin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11527] | 3907 | 0.378 | 0.5014 | No |
| 24 | HHIPL2 | HHIP like 2 [Source:HGNC Symbol;Acc:HGNC:25842] | 4095 | 0.342 | 0.4999 | No |
| 25 | THRB | thyroid hormone receptor beta [Source:HGNC Symbol;Acc:HGNC:11799] | 4212 | 0.321 | 0.5002 | No |
| 26 | KCNN1 | potassium calcium-activated channel subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:6290] | 4369 | 0.292 | 0.4990 | No |
| 27 | SEC31B | SEC31 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:23197] | 4376 | 0.291 | 0.5019 | No |
| 28 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 4409 | 0.286 | 0.5041 | No |
| 29 | CBL | Cbl proto-oncogene [Source:HGNC Symbol;Acc:HGNC:1541] | 4530 | 0.264 | 0.5036 | No |
| 30 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 4623 | 0.248 | 0.5038 | No |
| 31 | RPL10P17 | ribosomal protein L10 pseudogene 17 [Source:HGNC Symbol;Acc:HGNC:52348] | 4644 | 0.246 | 0.5058 | No |
| 32 | CBARP | CACN subunit beta associated regulatory protein [Source:HGNC Symbol;Acc:HGNC:28617] | 4919 | 0.205 | 0.5006 | No |
| 33 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 5362 | 0.139 | 0.4901 | No |
| 34 | ASPN | asporin [Source:HGNC Symbol;Acc:HGNC:14872] | 5609 | 0.109 | 0.4846 | No |
| 35 | ABCB11 | ATP binding cassette subfamily B member 11 [Source:HGNC Symbol;Acc:HGNC:42] | 5677 | 0.099 | 0.4838 | No |
| 36 | NPC1L1 | NPC1 like intracellular cholesterol transporter 1 [Source:HGNC Symbol;Acc:HGNC:7898] | 5949 | 0.062 | 0.4771 | No |
| 37 | CARD9 | caspase recruitment domain family member 9 [Source:HGNC Symbol;Acc:HGNC:16391] | 6260 | 0.014 | 0.4689 | No |
| 38 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6434 | 0.000 | 0.4642 | No |
| 39 | CCL27 | C-C motif chemokine ligand 27 [Source:HGNC Symbol;Acc:HGNC:10626] | 6451 | 0.000 | 0.4637 | No |
| 40 | IL1RL2 | interleukin 1 receptor like 2 [Source:HGNC Symbol;Acc:HGNC:5999] | 6935 | 0.000 | 0.4507 | No |
| 41 | EPHA5 | EPH receptor A5 [Source:HGNC Symbol;Acc:HGNC:3389] | 7439 | 0.000 | 0.4371 | No |
| 42 | SGK2 | serum/glucocorticoid regulated kinase 2 [Source:HGNC Symbol;Acc:HGNC:13900] | 7862 | 0.000 | 0.4256 | No |
| 43 | OR7A10 | olfactory receptor family 7 subfamily A member 10 [Source:HGNC Symbol;Acc:HGNC:8356] | 8074 | 0.000 | 0.4199 | No |
| 44 | PROP1 | PROP paired-like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9455] | 8309 | 0.000 | 0.4136 | No |
| 45 | SIM1 | SIM bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10882] | 8356 | 0.000 | 0.4124 | No |
| 46 | FOLR2 | folate receptor beta [Source:HGNC Symbol;Acc:HGNC:3793] | 9513 | 0.000 | 0.3811 | No |
| 47 | SERHL2 | serine hydrolase like 2 [Source:HGNC Symbol;Acc:HGNC:29446] | 9593 | 0.000 | 0.3789 | No |
| 48 | KCNF1 | potassium voltage-gated channel modifier subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:6246] | 9797 | 0.000 | 0.3734 | No |
| 49 | CETP | cholesteryl ester transfer protein [Source:HGNC Symbol;Acc:HGNC:1869] | 9865 | 0.000 | 0.3716 | No |
| 50 | GRM4 | glutamate metabotropic receptor 4 [Source:HGNC Symbol;Acc:HGNC:4596] | 9962 | 0.000 | 0.3690 | No |
| 51 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 9965 | 0.000 | 0.3690 | No |
| 52 | AADAC | arylacetamide deacetylase [Source:HGNC Symbol;Acc:HGNC:17] | 10363 | 0.000 | 0.3582 | No |
| 53 | LRRC31 | leucine rich repeat containing 31 [Source:HGNC Symbol;Acc:HGNC:26261] | 11355 | 0.000 | 0.3314 | No |
| 54 | IFI30 | IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398] | 11456 | 0.000 | 0.3287 | No |
| 55 | PRG2 | proteoglycan 2, pro eosinophil major basic protein [Source:HGNC Symbol;Acc:HGNC:9362] | 11481 | 0.000 | 0.3281 | No |
| 56 | LMAN1L | lectin, mannose binding 1 like [Source:HGNC Symbol;Acc:HGNC:6632] | 11788 | 0.000 | 0.3198 | No |
| 57 | SLC6A20 | solute carrier family 6 member 20 [Source:HGNC Symbol;Acc:HGNC:30927] | 11812 | 0.000 | 0.3192 | No |
| 58 | RYR2 | ryanodine receptor 2 [Source:HGNC Symbol;Acc:HGNC:10484] | 11837 | 0.000 | 0.3185 | No |
| 59 | CNN1 | calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155] | 12220 | 0.000 | 0.3082 | No |
| 60 | ADAMTSL2 | ADAMTS like 2 [Source:HGNC Symbol;Acc:HGNC:14631] | 12614 | 0.000 | 0.2975 | No |
| 61 | TENM2 | teneurin transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:29943] | 12728 | 0.000 | 0.2945 | No |
| 62 | LILRA4 | leukocyte immunoglobulin like receptor A4 [Source:HGNC Symbol;Acc:HGNC:15503] | 13387 | 0.000 | 0.2767 | No |
| 63 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13395 | 0.000 | 0.2765 | No |
| 64 | IL26 | interleukin 26 [Source:HGNC Symbol;Acc:HGNC:17119] | 13716 | 0.000 | 0.2678 | No |
| 65 | TMEM262 | transmembrane protein 262 [Source:HGNC Symbol;Acc:HGNC:49389] | 13795 | 0.000 | 0.2657 | No |
| 66 | KRT2 | keratin 2 [Source:HGNC Symbol;Acc:HGNC:6439] | 14104 | 0.000 | 0.2574 | No |
| 67 | B3GALT5 | beta-1,3-galactosyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:920] | 14420 | 0.000 | 0.2489 | No |
| 68 | C3orf36 | chromosome 3 putative open reading frame 36 [Source:HGNC Symbol;Acc:HGNC:26170] | 15988 | 0.000 | 0.2065 | No |
| 69 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16145 | 0.000 | 0.2022 | No |
| 70 | HYAL4 | hyaluronidase 4 [Source:HGNC Symbol;Acc:HGNC:5323] | 16227 | 0.000 | 0.2000 | No |
| 71 | HRG | histidine rich glycoprotein [Source:HGNC Symbol;Acc:HGNC:5181] | 17389 | 0.000 | 0.1686 | No |
| 72 | SLC9A3 | solute carrier family 9 member A3 [Source:HGNC Symbol;Acc:HGNC:11073] | 17461 | 0.000 | 0.1667 | No |
| 73 | CHRNG | cholinergic receptor nicotinic gamma subunit [Source:HGNC Symbol;Acc:HGNC:1967] | 17714 | 0.000 | 0.1599 | No |
| 74 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17724 | 0.000 | 0.1596 | No |
| 75 | IFNA17 | interferon alpha 17 [Source:HGNC Symbol;Acc:HGNC:5422] | 18072 | 0.000 | 0.1503 | No |
| 76 | PTPRCAP | protein tyrosine phosphatase receptor type C associated protein [Source:HGNC Symbol;Acc:HGNC:9667] | 18078 | 0.000 | 0.1501 | No |
| 77 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18785 | 0.000 | 0.1310 | No |
| 78 | DSG3 | desmoglein 3 [Source:HGNC Symbol;Acc:HGNC:3050] | 18802 | 0.000 | 0.1306 | No |
| 79 | MSC | musculin [Source:HGNC Symbol;Acc:HGNC:7321] | 18917 | 0.000 | 0.1275 | No |
| 80 | BMP4 | bone morphogenetic protein 4 [Source:HGNC Symbol;Acc:HGNC:1071] | 18938 | 0.000 | 0.1270 | No |
| 81 | EPS8L3 | EPS8 like 3 [Source:HGNC Symbol;Acc:HGNC:21297] | 18999 | 0.000 | 0.1253 | No |
| 82 | NGF | nerve growth factor [Source:HGNC Symbol;Acc:HGNC:7808] | 19140 | 0.000 | 0.1215 | No |
| 83 | HSD17B2 | hydroxysteroid 17-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5211] | 19632 | 0.000 | 0.1083 | No |
| 84 | NR1I3 | nuclear receptor subfamily 1 group I member 3 [Source:HGNC Symbol;Acc:HGNC:7969] | 19801 | 0.000 | 0.1037 | No |
| 85 | KLHDC8A | kelch domain containing 8A [Source:HGNC Symbol;Acc:HGNC:25573] | 19951 | 0.000 | 0.0997 | No |
| 86 | TCF21 | transcription factor 21 [Source:HGNC Symbol;Acc:HGNC:11632] | 20319 | 0.000 | 0.0898 | No |
| 87 | KLK1 | kallikrein 1 [Source:HGNC Symbol;Acc:HGNC:6357] | 20505 | 0.000 | 0.0847 | No |
| 88 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 20895 | 0.000 | 0.0742 | No |
| 89 | INSL5 | insulin like 5 [Source:HGNC Symbol;Acc:HGNC:6088] | 21620 | 0.000 | 0.0546 | No |
| 90 | INSL4 | insulin like 4 [Source:HGNC Symbol;Acc:HGNC:6087] | 21621 | 0.000 | 0.0546 | No |
| 91 | KRT17 | keratin 17 [Source:HGNC Symbol;Acc:HGNC:6427] | 21758 | 0.000 | 0.0510 | No |
| 92 | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1 [Source:HGNC Symbol;Acc:HGNC:9875] | 22645 | 0.000 | 0.0270 | No |
| 93 | ATP1B4 | ATPase Na+/K+ transporting family member beta 4 [Source:HGNC Symbol;Acc:HGNC:808] | 23068 | 0.000 | 0.0156 | No |
| 94 | FOXA1 | forkhead box A1 [Source:HGNC Symbol;Acc:HGNC:5021] | 23399 | 0.000 | 0.0066 | No |
| 95 | NPPB | natriuretic peptide B [Source:HGNC Symbol;Acc:HGNC:7940] | 23403 | 0.000 | 0.0065 | No |
| 96 | TCP10L3 | t-complex 10 like 3, pseudogene [Source:HGNC Symbol;Acc:HGNC:11656] | 23552 | 0.000 | 0.0025 | No |
| 97 | IGKV3D-15 | immunoglobulin kappa variable 3D-15 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5824] | 23568 | 0.000 | 0.0021 | No |
| 98 | NPFFR1 | neuropeptide FF receptor 1 [Source:HGNC Symbol;Acc:HGNC:17425] | 23943 | 0.000 | -0.0080 | No |
| 99 | CST5 | cystatin D [Source:HGNC Symbol;Acc:HGNC:2477] | 24425 | 0.000 | -0.0210 | No |
| 100 | CHRNA9 | cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079] | 24489 | 0.000 | -0.0227 | No |
| 101 | PRSS21 | serine protease 21 [Source:HGNC Symbol;Acc:HGNC:9485] | 24939 | 0.000 | -0.0349 | No |
| 102 | CAPN9 | calpain 9 [Source:HGNC Symbol;Acc:HGNC:1486] | 25561 | 0.000 | -0.0517 | No |
| 103 | PAGE1 | PAGE family member 1 [Source:HGNC Symbol;Acc:HGNC:4107] | 26160 | 0.000 | -0.0678 | No |
| 104 | MAGEA10 | MAGE family member A10 [Source:HGNC Symbol;Acc:HGNC:6797] | 26165 | 0.000 | -0.0679 | No |
| 105 | ITIH5 | inter-alpha-trypsin inhibitor heavy chain 5 [Source:HGNC Symbol;Acc:HGNC:21449] | 26552 | 0.000 | -0.0784 | No |
| 106 | ACE | angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] | 26728 | 0.000 | -0.0831 | No |
| 107 | BAAT | bile acid-CoA:amino acid N-acyltransferase [Source:HGNC Symbol;Acc:HGNC:932] | 26750 | 0.000 | -0.0837 | No |
| 108 | AGRP | agouti related neuropeptide [Source:HGNC Symbol;Acc:HGNC:330] | 27131 | -0.004 | -0.0939 | No |
| 109 | THBD | thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784] | 27398 | -0.047 | -0.1006 | No |
| 110 | MDFI | MyoD family inhibitor [Source:HGNC Symbol;Acc:HGNC:6967] | 27485 | -0.057 | -0.1024 | No |
| 111 | RBIS | ribosomal biogenesis factor [Source:HGNC Symbol;Acc:HGNC:32235] | 27511 | -0.060 | -0.1024 | No |
| 112 | SRD5A3 | steroid 5 alpha-reductase 3 [Source:HGNC Symbol;Acc:HGNC:25812] | 27906 | -0.110 | -0.1119 | No |
| 113 | SLC5A5 | solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040] | 28166 | -0.141 | -0.1174 | No |
| 114 | GRM2 | glutamate metabotropic receptor 2 [Source:HGNC Symbol;Acc:HGNC:4594] | 28233 | -0.150 | -0.1176 | No |
| 115 | VILL | villin like [Source:HGNC Symbol;Acc:HGNC:30906] | 28659 | -0.207 | -0.1269 | No |
| 116 | BRDT | bromodomain testis associated [Source:HGNC Symbol;Acc:HGNC:1105] | 29027 | -0.257 | -0.1342 | No |
| 117 | FCHO1 | FCH and mu domain containing endocytic adaptor 1 [Source:HGNC Symbol;Acc:HGNC:29002] | 29099 | -0.267 | -0.1333 | No |
| 118 | SPATA6 | spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309] | 29327 | -0.299 | -0.1362 | No |
| 119 | ZDHHC8P1 | ZDHHC8 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:26461] | 29386 | -0.311 | -0.1345 | No |
| 120 | DDX51 | DEAD-box helicase 51 [Source:HGNC Symbol;Acc:HGNC:20082] | 30776 | -0.520 | -0.1666 | No |
| 121 | DRC3 | dynein regulatory complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25384] | 32281 | -0.827 | -0.1986 | No |
| 122 | EGFL7 | EGF like domain multiple 7 [Source:HGNC Symbol;Acc:HGNC:20594] | 32775 | -0.957 | -0.2019 | No |
| 123 | SEMA5A | semaphorin 5A [Source:HGNC Symbol;Acc:HGNC:10736] | 33412 | -1.141 | -0.2070 | No |
| 124 | TYROBP | transmembrane immune signaling adaptor TYROBP [Source:HGNC Symbol;Acc:HGNC:12449] | 34116 | -1.382 | -0.2115 | No |
| 125 | DEPDC5 | DEP domain containing 5, GATOR1 subcomplex subunit [Source:HGNC Symbol;Acc:HGNC:18423] | 34242 | -1.430 | -0.1998 | No |
| 126 | PHLDA3 | pleckstrin homology like domain family A member 3 [Source:HGNC Symbol;Acc:HGNC:8934] | 34689 | -1.623 | -0.1947 | No |
| 127 | H2AC13 | H2A clustered histone 13 [Source:HGNC Symbol;Acc:HGNC:4725] | 34812 | -1.678 | -0.1803 | No |
| 128 | ECEL1 | endothelin converting enzyme like 1 [Source:HGNC Symbol;Acc:HGNC:3147] | 35562 | -2.123 | -0.1782 | No |
| 129 | KIF21B | kinesin family member 21B [Source:HGNC Symbol;Acc:HGNC:29442] | 35696 | -2.231 | -0.1583 | No |
| 130 | KLF3 | Kruppel like factor 3 [Source:HGNC Symbol;Acc:HGNC:16516] | 35788 | -2.305 | -0.1364 | No |
| 131 | ABCA3 | ATP binding cassette subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:33] | 35910 | -2.418 | -0.1142 | No |
| 132 | LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:6560] | 36488 | -3.010 | -0.0981 | No |
| 133 | TREM2 | triggering receptor expressed on myeloid cells 2 [Source:HGNC Symbol;Acc:HGNC:17761] | 36763 | -3.461 | -0.0690 | No |
| 134 | CACNA1S | calcium voltage-gated channel subunit alpha1 S [Source:HGNC Symbol;Acc:HGNC:1397] | 36873 | -3.687 | -0.0331 | No |
| 135 | CSF1R | colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433] | 36874 | -3.688 | 0.0058 | No |
