Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | RB_DN.V1_DN |
| Enrichment Score (ES) | 0.55744606 |
| Normalized Enrichment Score (NES) | 1.4775361 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.06889822 |
| FWER p-Value | 0.115 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TNC | tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] | 15 | 4.908 | 0.0371 | Yes |
| 2 | CISH | cytokine inducible SH2 containing protein [Source:HGNC Symbol;Acc:HGNC:1984] | 18 | 4.880 | 0.0742 | Yes |
| 3 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 46 | 4.625 | 0.1088 | Yes |
| 4 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 54 | 4.518 | 0.1431 | Yes |
| 5 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 68 | 4.348 | 0.1759 | Yes |
| 6 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 190 | 3.533 | 0.1996 | Yes |
| 7 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 199 | 3.493 | 0.2261 | Yes |
| 8 | PSMB10 | proteasome 20S subunit beta 10 [Source:HGNC Symbol;Acc:HGNC:9538] | 209 | 3.421 | 0.2519 | Yes |
| 9 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 232 | 3.304 | 0.2766 | Yes |
| 10 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 433 | 2.515 | 0.2904 | Yes |
| 11 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 474 | 2.407 | 0.3076 | Yes |
| 12 | HSPA5 | heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238] | 489 | 2.381 | 0.3254 | Yes |
| 13 | ATF5 | activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790] | 543 | 2.249 | 0.3412 | Yes |
| 14 | AGRN | agrin [Source:HGNC Symbol;Acc:HGNC:329] | 561 | 2.221 | 0.3577 | Yes |
| 15 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 585 | 2.161 | 0.3735 | Yes |
| 16 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 728 | 1.940 | 0.3845 | Yes |
| 17 | CHAC1 | ChaC glutathione specific gamma-glutamylcyclotransferase 1 [Source:HGNC Symbol;Acc:HGNC:28680] | 763 | 1.875 | 0.3979 | Yes |
| 18 | ANKFY1 | ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20763] | 818 | 1.773 | 0.4100 | Yes |
| 19 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 872 | 1.694 | 0.4215 | Yes |
| 20 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 998 | 1.554 | 0.4299 | Yes |
| 21 | CD9 | CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709] | 1060 | 1.500 | 0.4397 | Yes |
| 22 | MMP13 | matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159] | 1073 | 1.492 | 0.4508 | Yes |
| 23 | BASP1 | brain abundant membrane attached signal protein 1 [Source:HGNC Symbol;Acc:HGNC:957] | 1142 | 1.439 | 0.4599 | Yes |
| 24 | SLC7A5 | solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063] | 1266 | 1.338 | 0.4668 | Yes |
| 25 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 1384 | 1.254 | 0.4732 | Yes |
| 26 | NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 [Source:HGNC Symbol;Acc:HGNC:7733] | 1428 | 1.223 | 0.4814 | Yes |
| 27 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 1431 | 1.222 | 0.4907 | Yes |
| 28 | DDIT3 | DNA damage inducible transcript 3 [Source:HGNC Symbol;Acc:HGNC:2726] | 1487 | 1.182 | 0.4982 | Yes |
| 29 | BCCIP | BRCA2 and CDKN1A interacting protein [Source:HGNC Symbol;Acc:HGNC:978] | 1772 | 1.021 | 0.4983 | Yes |
| 30 | PRKAR1A | protein kinase cAMP-dependent type I regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9388] | 1787 | 1.014 | 0.5057 | Yes |
| 31 | DYNLL1 | dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476] | 1822 | 1.001 | 0.5124 | Yes |
| 32 | DDIT4 | DNA damage inducible transcript 4 [Source:HGNC Symbol;Acc:HGNC:24944] | 1824 | 0.999 | 0.5200 | Yes |
| 33 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 1842 | 0.989 | 0.5271 | Yes |
| 34 | STARD3NL | STARD3 N-terminal like [Source:HGNC Symbol;Acc:HGNC:19169] | 1877 | 0.975 | 0.5336 | Yes |
| 35 | TMEM50B | transmembrane protein 50B [Source:HGNC Symbol;Acc:HGNC:1280] | 1884 | 0.973 | 0.5409 | Yes |
| 36 | TMEM42 | transmembrane protein 42 [Source:HGNC Symbol;Acc:HGNC:28444] | 1956 | 0.935 | 0.5461 | Yes |
| 37 | PPP2R1B | protein phosphatase 2 scaffold subunit Abeta [Source:HGNC Symbol;Acc:HGNC:9303] | 2257 | 0.815 | 0.5442 | Yes |
| 38 | SH3BP5L | SH3 binding domain protein 5 like [Source:HGNC Symbol;Acc:HGNC:29360] | 2268 | 0.813 | 0.5501 | Yes |
| 39 | DDX3Y | DEAD-box helicase 3 Y-linked [Source:HGNC Symbol;Acc:HGNC:2699] | 2363 | 0.777 | 0.5535 | Yes |
| 40 | P4HA1 | prolyl 4-hydroxylase subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8546] | 2675 | 0.676 | 0.5503 | Yes |
| 41 | SLCO2A1 | solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955] | 2770 | 0.646 | 0.5527 | Yes |
| 42 | SLC7A3 | solute carrier family 7 member 3 [Source:HGNC Symbol;Acc:HGNC:11061] | 2776 | 0.645 | 0.5574 | Yes |
| 43 | CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Source:HGNC Symbol;Acc:HGNC:1769] | 3270 | 0.514 | 0.5480 | No |
| 44 | UROS | uroporphyrinogen III synthase [Source:HGNC Symbol;Acc:HGNC:12592] | 3686 | 0.423 | 0.5400 | No |
| 45 | CAP1 | cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040] | 3908 | 0.378 | 0.5369 | No |
| 46 | UBA5 | ubiquitin like modifier activating enzyme 5 [Source:HGNC Symbol;Acc:HGNC:23230] | 4009 | 0.358 | 0.5370 | No |
| 47 | NKAP | NFKB activating protein [Source:HGNC Symbol;Acc:HGNC:29873] | 4141 | 0.334 | 0.5360 | No |
| 48 | CALCB | calcitonin related polypeptide beta [Source:HGNC Symbol;Acc:HGNC:1438] | 4304 | 0.301 | 0.5339 | No |
| 49 | ARL1 | ADP ribosylation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:692] | 4448 | 0.278 | 0.5321 | No |
| 50 | LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [Source:HGNC Symbol;Acc:HGNC:15606] | 4493 | 0.270 | 0.5330 | No |
| 51 | FEZ2 | fasciculation and elongation protein zeta 2 [Source:HGNC Symbol;Acc:HGNC:3660] | 4791 | 0.221 | 0.5267 | No |
| 52 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 4987 | 0.192 | 0.5229 | No |
| 53 | TMCC3 | transmembrane and coiled-coil domain family 3 [Source:HGNC Symbol;Acc:HGNC:29199] | 5395 | 0.135 | 0.5129 | No |
| 54 | MSMO1 | methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545] | 5432 | 0.129 | 0.5129 | No |
| 55 | LAMC2 | laminin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:6493] | 5929 | 0.064 | 0.5000 | No |
| 56 | LMAN1 | lectin, mannose binding 1 [Source:HGNC Symbol;Acc:HGNC:6631] | 5942 | 0.062 | 0.5001 | No |
| 57 | EIF4E | eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:HGNC:3287] | 6009 | 0.053 | 0.4987 | No |
| 58 | PDCD6 | programmed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765] | 6256 | 0.015 | 0.4922 | No |
| 59 | CYTH1 | cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501] | 6258 | 0.015 | 0.4923 | No |
| 60 | LCE5A | late cornified envelope 5A [Source:HGNC Symbol;Acc:HGNC:16614] | 9401 | 0.000 | 0.4073 | No |
| 61 | RASL11B | RAS like family 11 member B [Source:HGNC Symbol;Acc:HGNC:23804] | 9742 | 0.000 | 0.3981 | No |
| 62 | ADAM12 | ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190] | 9929 | 0.000 | 0.3931 | No |
| 63 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 10000 | 0.000 | 0.3912 | No |
| 64 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 10945 | 0.000 | 0.3656 | No |
| 65 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 11064 | 0.000 | 0.3624 | No |
| 66 | C10orf99 | chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428] | 11104 | 0.000 | 0.3614 | No |
| 67 | S100A16 | S100 calcium binding protein A16 [Source:HGNC Symbol;Acc:HGNC:20441] | 11656 | 0.000 | 0.3465 | No |
| 68 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 11730 | 0.000 | 0.3445 | No |
| 69 | AGR3 | anterior gradient 3, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:24167] | 12043 | 0.000 | 0.3361 | No |
| 70 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12458 | 0.000 | 0.3249 | No |
| 71 | MOXD1 | monooxygenase DBH like 1 [Source:HGNC Symbol;Acc:HGNC:21063] | 12980 | 0.000 | 0.3108 | No |
| 72 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 13771 | 0.000 | 0.2894 | No |
| 73 | TLL1 | tolloid like 1 [Source:HGNC Symbol;Acc:HGNC:11843] | 14072 | 0.000 | 0.2813 | No |
| 74 | GJB2 | gap junction protein beta 2 [Source:HGNC Symbol;Acc:HGNC:4284] | 15421 | 0.000 | 0.2448 | No |
| 75 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16313 | 0.000 | 0.2207 | No |
| 76 | H19 | H19 imprinted maternally expressed transcript [Source:HGNC Symbol;Acc:HGNC:4713] | 17051 | 0.000 | 0.2008 | No |
| 77 | S1PR5 | sphingosine-1-phosphate receptor 5 [Source:HGNC Symbol;Acc:HGNC:14299] | 17872 | 0.000 | 0.1786 | No |
| 78 | BNC1 | basonuclin 1 [Source:HGNC Symbol;Acc:HGNC:1081] | 19131 | 0.000 | 0.1446 | No |
| 79 | F2RL1 | F2R like trypsin receptor 1 [Source:HGNC Symbol;Acc:HGNC:3538] | 20945 | 0.000 | 0.0955 | No |
| 80 | LRRC4 | leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586] | 22537 | 0.000 | 0.0525 | No |
| 81 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 23463 | 0.000 | 0.0275 | No |
| 82 | C18orf32 | chromosome 18 open reading frame 32 [Source:HGNC Symbol;Acc:HGNC:31690] | 24225 | 0.000 | 0.0069 | No |
| 83 | CST9 | cystatin 9 [Source:HGNC Symbol;Acc:HGNC:13261] | 24421 | 0.000 | 0.0016 | No |
| 84 | WNT3 | Wnt family member 3 [Source:HGNC Symbol;Acc:HGNC:12782] | 24813 | 0.000 | -0.0090 | No |
| 85 | FHL1 | four and a half LIM domains 1 [Source:HGNC Symbol;Acc:HGNC:3702] | 25473 | 0.000 | -0.0268 | No |
| 86 | ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10870] | 26620 | 0.000 | -0.0578 | No |
| 87 | CELSR1 | cadherin EGF LAG seven-pass G-type receptor 1 [Source:HGNC Symbol;Acc:HGNC:1850] | 27241 | -0.022 | -0.0744 | No |
| 88 | EFL1 | elongation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25789] | 27873 | -0.105 | -0.0907 | No |
| 89 | SARAF | store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789] | 28025 | -0.125 | -0.0938 | No |
| 90 | RPS2 | ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404] | 28109 | -0.135 | -0.0950 | No |
| 91 | GOSR2 | golgi SNAP receptor complex member 2 [Source:HGNC Symbol;Acc:HGNC:4431] | 28661 | -0.207 | -0.1083 | No |
| 92 | NFIL3 | nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:HGNC:7787] | 29018 | -0.256 | -0.1160 | No |
| 93 | MYORG | myogenesis regulating glycosidase (putative) [Source:HGNC Symbol;Acc:HGNC:19918] | 29082 | -0.266 | -0.1157 | No |
| 94 | RHOV | ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313] | 29121 | -0.271 | -0.1146 | No |
| 95 | UNC119B | unc-119 lipid binding chaperone B [Source:HGNC Symbol;Acc:HGNC:16488] | 29181 | -0.279 | -0.1141 | No |
| 96 | DNAJC4 | DnaJ heat shock protein family (Hsp40) member C4 [Source:HGNC Symbol;Acc:HGNC:5271] | 29352 | -0.304 | -0.1164 | No |
| 97 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 29695 | -0.353 | -0.1229 | No |
| 98 | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1 [Source:HGNC Symbol;Acc:HGNC:217] | 29794 | -0.367 | -0.1228 | No |
| 99 | IRX4 | iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6129] | 29826 | -0.372 | -0.1208 | No |
| 100 | H2BC14 | H2B clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4750] | 30342 | -0.447 | -0.1313 | No |
| 101 | ANXA11 | annexin A11 [Source:HGNC Symbol;Acc:HGNC:535] | 30370 | -0.452 | -0.1286 | No |
| 102 | SEC23A | Sec23 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10701] | 30481 | -0.468 | -0.1280 | No |
| 103 | ANKRD40 | ankyrin repeat domain 40 [Source:HGNC Symbol;Acc:HGNC:28233] | 30693 | -0.504 | -0.1299 | No |
| 104 | CAV1 | caveolin 1 [Source:HGNC Symbol;Acc:HGNC:1527] | 31616 | -0.673 | -0.1497 | No |
| 105 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 32259 | -0.821 | -0.1608 | No |
| 106 | SMIM3 | small integral membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:30248] | 32438 | -0.866 | -0.1590 | No |
| 107 | CREB3L2 | cAMP responsive element binding protein 3 like 2 [Source:HGNC Symbol;Acc:HGNC:23720] | 32950 | -1.001 | -0.1651 | No |
| 108 | CTNNAL1 | catenin alpha like 1 [Source:HGNC Symbol;Acc:HGNC:2512] | 33256 | -1.092 | -0.1651 | No |
| 109 | TRAPPC12 | trafficking protein particle complex 12 [Source:HGNC Symbol;Acc:HGNC:24284] | 33257 | -1.093 | -0.1567 | No |
| 110 | CDC42SE2 | CDC42 small effector 2 [Source:HGNC Symbol;Acc:HGNC:18547] | 34035 | -1.355 | -0.1674 | No |
| 111 | PMVK | phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141] | 34763 | -1.654 | -0.1744 | No |
| 112 | H2BC4 | H2B clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4757] | 34860 | -1.697 | -0.1641 | No |
| 113 | SQLE | squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279] | 35094 | -1.821 | -0.1565 | No |
| 114 | MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24693] | 35104 | -1.828 | -0.1428 | No |
| 115 | NSDHL | NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398] | 35194 | -1.884 | -0.1308 | No |
| 116 | FAM102A | family with sequence similarity 102 member A [Source:HGNC Symbol;Acc:HGNC:31419] | 35734 | -2.263 | -0.1281 | No |
| 117 | PLXNA2 | plexin A2 [Source:HGNC Symbol;Acc:HGNC:9100] | 36075 | -2.576 | -0.1176 | No |
| 118 | ANXA6 | annexin A6 [Source:HGNC Symbol;Acc:HGNC:544] | 36205 | -2.726 | -0.1003 | No |
| 119 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 36283 | -2.797 | -0.0811 | No |
| 120 | LIFR | LIF receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6597] | 36366 | -2.888 | -0.0612 | No |
| 121 | COL18A1 | collagen type XVIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2195] | 36379 | -2.901 | -0.0394 | No |
| 122 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36916 | -3.817 | -0.0248 | No |
| 123 | NDRG1 | N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679] | 36925 | -3.862 | 0.0045 | No |
