Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | RB_DN.V1_UP |
| Enrichment Score (ES) | -0.708558 |
| Normalized Enrichment Score (NES) | -1.4872233 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.034210913 |
| FWER p-Value | 0.08 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ID1 | inhibitor of DNA binding 1, HLH protein [Source:HGNC Symbol;Acc:HGNC:5360] | 78 | 4.234 | 0.0234 | No |
| 2 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 251 | 3.232 | 0.0383 | No |
| 3 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 454 | 2.459 | 0.0477 | No |
| 4 | BTG2 | BTG anti-proliferation factor 2 [Source:HGNC Symbol;Acc:HGNC:1131] | 563 | 2.219 | 0.0581 | No |
| 5 | SLC7A7 | solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065] | 638 | 2.089 | 0.0687 | No |
| 6 | MDM2 | MDM2 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:6973] | 656 | 2.060 | 0.0807 | No |
| 7 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 671 | 2.029 | 0.0926 | No |
| 8 | PRKCE | protein kinase C epsilon [Source:HGNC Symbol;Acc:HGNC:9401] | 1887 | 0.969 | 0.0656 | No |
| 9 | ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10864] | 2139 | 0.862 | 0.0640 | No |
| 10 | PLA2G6 | phospholipase A2 group VI [Source:HGNC Symbol;Acc:HGNC:9039] | 2164 | 0.851 | 0.0685 | No |
| 11 | PRKAB1 | protein kinase AMP-activated non-catalytic subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:9378] | 2410 | 0.763 | 0.0664 | No |
| 12 | ADGRE1 | adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336] | 4004 | 0.359 | 0.0255 | No |
| 13 | NOXO1 | NADPH oxidase organizer 1 [Source:HGNC Symbol;Acc:HGNC:19404] | 5252 | 0.155 | -0.0073 | No |
| 14 | NUDT5 | nudix hydrolase 5 [Source:HGNC Symbol;Acc:HGNC:8052] | 5833 | 0.078 | -0.0225 | No |
| 15 | FXYD6 | FXYD domain containing ion transport regulator 6 [Source:HGNC Symbol;Acc:HGNC:4030] | 6673 | 0.000 | -0.0452 | No |
| 16 | HES1 | hes family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:5192] | 7206 | 0.000 | -0.0596 | No |
| 17 | ARTN | artemin [Source:HGNC Symbol;Acc:HGNC:727] | 7478 | 0.000 | -0.0669 | No |
| 18 | FBP1 | fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606] | 8224 | 0.000 | -0.0871 | No |
| 19 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8812 | 0.000 | -0.1029 | No |
| 20 | TNFRSF18 | TNF receptor superfamily member 18 [Source:HGNC Symbol;Acc:HGNC:11914] | 9197 | 0.000 | -0.1133 | No |
| 21 | GRB7 | growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567] | 9866 | 0.000 | -0.1314 | No |
| 22 | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin [Source:HGNC Symbol;Acc:HGNC:9016] | 9868 | 0.000 | -0.1314 | No |
| 23 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 9965 | 0.000 | -0.1340 | No |
| 24 | OVOL2 | ovo like zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:15804] | 10705 | 0.000 | -0.1540 | No |
| 25 | LYNX1 | Ly6/neurotoxin 1 [Source:HGNC Symbol;Acc:HGNC:29604] | 11491 | 0.000 | -0.1752 | No |
| 26 | IL36RN | interleukin 36 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:15561] | 12521 | 0.000 | -0.2031 | No |
| 27 | DDIT4L | DNA damage inducible transcript 4 like [Source:HGNC Symbol;Acc:HGNC:30555] | 13367 | 0.000 | -0.2259 | No |
| 28 | MANSC1 | MANSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25505] | 13842 | 0.000 | -0.2387 | No |
| 29 | PCDH10 | protocadherin 10 [Source:HGNC Symbol;Acc:HGNC:13404] | 14534 | 0.000 | -0.2574 | No |
| 30 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 15994 | 0.000 | -0.2969 | No |
| 31 | PALMD | palmdelphin [Source:HGNC Symbol;Acc:HGNC:15846] | 16641 | 0.000 | -0.3144 | No |
| 32 | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251] | 16986 | 0.000 | -0.3237 | No |
| 33 | SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 [Source:HGNC Symbol;Acc:HGNC:11097] | 19607 | 0.000 | -0.3945 | No |
| 34 | TMEM54 | transmembrane protein 54 [Source:HGNC Symbol;Acc:HGNC:24143] | 20083 | 0.000 | -0.4074 | No |
| 35 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 21640 | 0.000 | -0.4494 | No |
| 36 | SFRP1 | secreted frizzled related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776] | 23336 | 0.000 | -0.4953 | No |
| 37 | SNAP25 | synaptosome associated protein 25 [Source:HGNC Symbol;Acc:HGNC:11132] | 23873 | 0.000 | -0.5098 | No |
| 38 | DUOXA1 | dual oxidase maturation factor 1 [Source:HGNC Symbol;Acc:HGNC:26507] | 25564 | 0.000 | -0.5555 | No |
| 39 | ALPK3 | alpha kinase 3 [Source:HGNC Symbol;Acc:HGNC:17574] | 27245 | -0.023 | -0.6008 | No |
| 40 | SLC24A1 | solute carrier family 24 member 1 [Source:HGNC Symbol;Acc:HGNC:10975] | 27636 | -0.073 | -0.6109 | No |
| 41 | HEY2 | hes related family bHLH transcription factor with YRPW motif 2 [Source:HGNC Symbol;Acc:HGNC:4881] | 27669 | -0.077 | -0.6113 | No |
| 42 | POLD4 | DNA polymerase delta 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:14106] | 27951 | -0.116 | -0.6182 | No |
| 43 | TIMELESS | timeless circadian regulator [Source:HGNC Symbol;Acc:HGNC:11813] | 28224 | -0.148 | -0.6247 | No |
| 44 | TGM1 | transglutaminase 1 [Source:HGNC Symbol;Acc:HGNC:11777] | 28573 | -0.196 | -0.6329 | No |
| 45 | ZFP30 | ZFP30 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:29555] | 28805 | -0.228 | -0.6378 | No |
| 46 | UCK1 | uridine-cytidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:14859] | 29052 | -0.261 | -0.6428 | No |
| 47 | MAN1B1 | mannosidase alpha class 1B member 1 [Source:HGNC Symbol;Acc:HGNC:6823] | 29333 | -0.300 | -0.6486 | No |
| 48 | PLEKHA6 | pleckstrin homology domain containing A6 [Source:HGNC Symbol;Acc:HGNC:17053] | 29631 | -0.344 | -0.6546 | No |
| 49 | ZSCAN22 | zinc finger and SCAN domain containing 22 [Source:HGNC Symbol;Acc:HGNC:4929] | 29971 | -0.392 | -0.6614 | No |
| 50 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 30477 | -0.467 | -0.6722 | No |
| 51 | ACOX3 | acyl-CoA oxidase 3, pristanoyl [Source:HGNC Symbol;Acc:HGNC:121] | 30975 | -0.552 | -0.6823 | No |
| 52 | GAB3 | GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515] | 31433 | -0.635 | -0.6908 | No |
| 53 | SULF2 | sulfatase 2 [Source:HGNC Symbol;Acc:HGNC:20392] | 31729 | -0.694 | -0.6946 | No |
| 54 | SLC2A9 | solute carrier family 2 member 9 [Source:HGNC Symbol;Acc:HGNC:13446] | 31799 | -0.714 | -0.6922 | No |
| 55 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 32355 | -0.847 | -0.7021 | No |
| 56 | EI24 | EI24 autophagy associated transmembrane protein [Source:HGNC Symbol;Acc:HGNC:13276] | 32595 | -0.904 | -0.7031 | Yes |
| 57 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 32784 | -0.959 | -0.7024 | Yes |
| 58 | PCBP2 | poly(rC) binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8648] | 32790 | -0.961 | -0.6967 | Yes |
| 59 | MRPL49 | mitochondrial ribosomal protein L49 [Source:HGNC Symbol;Acc:HGNC:1176] | 32900 | -0.988 | -0.6937 | Yes |
| 60 | AHCY | adenosylhomocysteinase [Source:HGNC Symbol;Acc:HGNC:343] | 32929 | -0.997 | -0.6885 | Yes |
| 61 | ZW10 | zw10 kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13194] | 32984 | -1.010 | -0.6838 | Yes |
| 62 | CRIP2 | cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361] | 33008 | -1.019 | -0.6783 | Yes |
| 63 | BAZ1B | bromodomain adjacent to zinc finger domain 1B [Source:HGNC Symbol;Acc:HGNC:961] | 33124 | -1.054 | -0.6751 | Yes |
| 64 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33245 | -1.087 | -0.6717 | Yes |
| 65 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33258 | -1.093 | -0.6655 | Yes |
| 66 | CTDSP1 | CTD small phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:21614] | 33392 | -1.135 | -0.6622 | Yes |
| 67 | MAPK13 | mitogen-activated protein kinase 13 [Source:HGNC Symbol;Acc:HGNC:6875] | 33824 | -1.276 | -0.6662 | Yes |
| 68 | LCMT1 | leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557] | 34010 | -1.346 | -0.6631 | Yes |
| 69 | GANC | glucosidase alpha, neutral C [Source:HGNC Symbol;Acc:HGNC:4139] | 34029 | -1.351 | -0.6554 | Yes |
| 70 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 34151 | -1.393 | -0.6503 | Yes |
| 71 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 34301 | -1.457 | -0.6455 | Yes |
| 72 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 34333 | -1.473 | -0.6374 | Yes |
| 73 | AAAS | aladin WD repeat nucleoporin [Source:HGNC Symbol;Acc:HGNC:13666] | 34395 | -1.498 | -0.6301 | Yes |
| 74 | NANS | N-acetylneuraminate synthase [Source:HGNC Symbol;Acc:HGNC:19237] | 34454 | -1.524 | -0.6224 | Yes |
| 75 | MRPL45 | mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651] | 34527 | -1.551 | -0.6150 | Yes |
| 76 | NUMBL | NUMB like endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8061] | 34560 | -1.566 | -0.6064 | Yes |
| 77 | ADA | adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186] | 34642 | -1.602 | -0.5989 | Yes |
| 78 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 34707 | -1.630 | -0.5908 | Yes |
| 79 | MRE11 | MRE11 homolog, double strand break repair nuclease [Source:HGNC Symbol;Acc:HGNC:7230] | 34836 | -1.689 | -0.5841 | Yes |
| 80 | IFT27 | intraflagellar transport 27 [Source:HGNC Symbol;Acc:HGNC:18626] | 34918 | -1.729 | -0.5759 | Yes |
| 81 | GNB1L | G protein subunit beta 1 like [Source:HGNC Symbol;Acc:HGNC:4397] | 34961 | -1.752 | -0.5664 | Yes |
| 82 | TKFC | triokinase and FMN cyclase [Source:HGNC Symbol;Acc:HGNC:24552] | 35027 | -1.783 | -0.5574 | Yes |
| 83 | TIPIN | TIMELESS interacting protein [Source:HGNC Symbol;Acc:HGNC:30750] | 35066 | -1.805 | -0.5476 | Yes |
| 84 | PEX11B | peroxisomal biogenesis factor 11 beta [Source:HGNC Symbol;Acc:HGNC:8853] | 35168 | -1.860 | -0.5391 | Yes |
| 85 | RAD51C | RAD51 paralog C [Source:HGNC Symbol;Acc:HGNC:9820] | 35456 | -2.055 | -0.5344 | Yes |
| 86 | STUB1 | STIP1 homology and U-box containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11427] | 35483 | -2.072 | -0.5226 | Yes |
| 87 | VPS16 | VPS16 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14584] | 35781 | -2.303 | -0.5168 | Yes |
| 88 | PDXP | pyridoxal phosphatase [Source:HGNC Symbol;Acc:HGNC:30259] | 35826 | -2.342 | -0.5038 | Yes |
| 89 | PLXNB2 | plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104] | 35830 | -2.344 | -0.4898 | Yes |
| 90 | PMS2 | PMS1 homolog 2, mismatch repair system component [Source:HGNC Symbol;Acc:HGNC:9122] | 35865 | -2.377 | -0.4763 | Yes |
| 91 | PPM1M | protein phosphatase, Mg2+/Mn2+ dependent 1M [Source:HGNC Symbol;Acc:HGNC:26506] | 35879 | -2.389 | -0.4623 | Yes |
| 92 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 35965 | -2.473 | -0.4497 | Yes |
| 93 | DNASE1L1 | deoxyribonuclease 1 like 1 [Source:HGNC Symbol;Acc:HGNC:2957] | 35974 | -2.478 | -0.4349 | Yes |
| 94 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36000 | -2.501 | -0.4205 | Yes |
| 95 | SPICE1 | spindle and centriole associated protein 1 [Source:HGNC Symbol;Acc:HGNC:25083] | 36019 | -2.513 | -0.4058 | Yes |
| 96 | NME4 | NME/NM23 nucleoside diphosphate kinase 4 [Source:HGNC Symbol;Acc:HGNC:7852] | 36042 | -2.544 | -0.3911 | Yes |
| 97 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36099 | -2.607 | -0.3768 | Yes |
| 98 | MMGT1 | membrane magnesium transporter 1 [Source:HGNC Symbol;Acc:HGNC:28100] | 36107 | -2.614 | -0.3613 | Yes |
| 99 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36187 | -2.707 | -0.3471 | Yes |
| 100 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 36266 | -2.780 | -0.3324 | Yes |
| 101 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 36346 | -2.873 | -0.3172 | Yes |
| 102 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36358 | -2.884 | -0.3001 | Yes |
| 103 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 36365 | -2.887 | -0.2828 | Yes |
| 104 | TPRA1 | transmembrane protein adipocyte associated 1 [Source:HGNC Symbol;Acc:HGNC:30413] | 36386 | -2.912 | -0.2658 | Yes |
| 105 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36491 | -3.015 | -0.2504 | Yes |
| 106 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 36605 | -3.169 | -0.2343 | Yes |
| 107 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36606 | -3.169 | -0.2152 | Yes |
| 108 | THRA | thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796] | 36646 | -3.221 | -0.1968 | Yes |
| 109 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36667 | -3.270 | -0.1776 | Yes |
| 110 | MSH6 | mutS homolog 6 [Source:HGNC Symbol;Acc:HGNC:7329] | 36676 | -3.285 | -0.1580 | Yes |
| 111 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36821 | -3.579 | -0.1403 | Yes |
| 112 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36891 | -3.747 | -0.1196 | Yes |
| 113 | CLN6 | CLN6 transmembrane ER protein [Source:HGNC Symbol;Acc:HGNC:2077] | 36957 | -3.970 | -0.0974 | Yes |
| 114 | PMM1 | phosphomannomutase 1 [Source:HGNC Symbol;Acc:HGNC:9114] | 36961 | -3.983 | -0.0734 | Yes |
| 115 | SLC2A8 | solute carrier family 2 member 8 [Source:HGNC Symbol;Acc:HGNC:13812] | 36998 | -4.120 | -0.0495 | Yes |
| 116 | EPHX1 | epoxide hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3401] | 37001 | -4.148 | -0.0246 | Yes |
| 117 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 37055 | -4.466 | 0.0009 | Yes |
