Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | RB_P107_DN.V1_UP |
| Enrichment Score (ES) | -0.73311824 |
| Normalized Enrichment Score (NES) | -1.5593337 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.004791069 |
| FWER p-Value | 0.006 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 122 | 3.964 | 0.0176 | No |
| 2 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 198 | 3.495 | 0.0341 | No |
| 3 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 340 | 2.823 | 0.0452 | No |
| 4 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 475 | 2.404 | 0.0542 | No |
| 5 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 687 | 2.005 | 0.0591 | No |
| 6 | TRPV2 | transient receptor potential cation channel subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:18082] | 1297 | 1.313 | 0.0496 | No |
| 7 | FBN1 | fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603] | 1561 | 1.142 | 0.0485 | No |
| 8 | SPIRE2 | spire type actin nucleation factor 2 [Source:HGNC Symbol;Acc:HGNC:30623] | 2129 | 0.866 | 0.0377 | No |
| 9 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 2429 | 0.759 | 0.0336 | No |
| 10 | TAGLN | transgelin [Source:HGNC Symbol;Acc:HGNC:11553] | 4221 | 0.319 | -0.0131 | No |
| 11 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 5200 | 0.161 | -0.0387 | No |
| 12 | CA2 | carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] | 5283 | 0.151 | -0.0402 | No |
| 13 | H1-10 | H1.10 linker histone [Source:HGNC Symbol;Acc:HGNC:4722] | 5486 | 0.122 | -0.0450 | No |
| 14 | RBPMS2 | RNA binding protein, mRNA processing factor 2 [Source:HGNC Symbol;Acc:HGNC:19098] | 5593 | 0.110 | -0.0473 | No |
| 15 | FANCL | FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748] | 5971 | 0.057 | -0.0572 | No |
| 16 | SI | sucrase-isomaltase [Source:HGNC Symbol;Acc:HGNC:10856] | 6131 | 0.034 | -0.0613 | No |
| 17 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 6236 | 0.018 | -0.0640 | No |
| 18 | CES5A | carboxylesterase 5A [Source:HGNC Symbol;Acc:HGNC:26459] | 6734 | 0.000 | -0.0775 | No |
| 19 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 8097 | 0.000 | -0.1143 | No |
| 20 | CDH2 | cadherin 2 [Source:HGNC Symbol;Acc:HGNC:1759] | 9466 | 0.000 | -0.1513 | No |
| 21 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9670 | 0.000 | -0.1568 | No |
| 22 | ABAT | 4-aminobutyrate aminotransferase [Source:HGNC Symbol;Acc:HGNC:23] | 10547 | 0.000 | -0.1805 | No |
| 23 | FBLN2 | fibulin 2 [Source:HGNC Symbol;Acc:HGNC:3601] | 11244 | 0.000 | -0.1993 | No |
| 24 | LYPD1 | LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28431] | 11995 | 0.000 | -0.2196 | No |
| 25 | BICC1 | BicC family RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19351] | 12419 | 0.000 | -0.2311 | No |
| 26 | SLIT3 | slit guidance ligand 3 [Source:HGNC Symbol;Acc:HGNC:11087] | 12562 | 0.000 | -0.2349 | No |
| 27 | CDKN1C | cyclin dependent kinase inhibitor 1C [Source:HGNC Symbol;Acc:HGNC:1786] | 12604 | 0.000 | -0.2360 | No |
| 28 | COL1A2 | collagen type I alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2198] | 12858 | 0.000 | -0.2429 | No |
| 29 | TMEM119 | transmembrane protein 119 [Source:HGNC Symbol;Acc:HGNC:27884] | 13435 | 0.000 | -0.2585 | No |
| 30 | TMEM45B | transmembrane protein 45B [Source:HGNC Symbol;Acc:HGNC:25194] | 14681 | 0.000 | -0.2921 | No |
| 31 | BGN | biglycan [Source:HGNC Symbol;Acc:HGNC:1044] | 15538 | 0.000 | -0.3153 | No |
| 32 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 15994 | 0.000 | -0.3276 | No |
| 33 | EFS | embryonal Fyn-associated substrate [Source:HGNC Symbol;Acc:HGNC:16898] | 16285 | 0.000 | -0.3355 | No |
| 34 | COL16A1 | collagen type XVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2193] | 16426 | 0.000 | -0.3392 | No |
| 35 | BEX2 | brain expressed X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30933] | 16522 | 0.000 | -0.3418 | No |
| 36 | SRPX2 | sushi repeat containing protein X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30668] | 17426 | 0.000 | -0.3662 | No |
| 37 | COL6A2 | collagen type VI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2212] | 18595 | 0.000 | -0.3978 | No |
| 38 | COL6A1 | collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211] | 18596 | 0.000 | -0.3978 | No |
| 39 | FKBP10 | FKBP prolyl isomerase 10 [Source:HGNC Symbol;Acc:HGNC:18169] | 18852 | 0.000 | -0.4047 | No |
| 40 | KHDRBS3 | KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117] | 19516 | 0.000 | -0.4227 | No |
| 41 | LOXL1 | lysyl oxidase like 1 [Source:HGNC Symbol;Acc:HGNC:6665] | 19653 | 0.000 | -0.4264 | No |
| 42 | COL5A1 | collagen type V alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2209] | 20203 | 0.000 | -0.4412 | No |
| 43 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 20895 | 0.000 | -0.4599 | No |
| 44 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 21132 | 0.000 | -0.4663 | No |
| 45 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 21640 | 0.000 | -0.4800 | No |
| 46 | COX6B2 | cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380] | 24033 | 0.000 | -0.5447 | No |
| 47 | TSSC4 | tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;Acc:HGNC:12386] | 24329 | 0.000 | -0.5527 | No |
| 48 | SNCG | synuclein gamma [Source:HGNC Symbol;Acc:HGNC:11141] | 25338 | 0.000 | -0.5800 | No |
| 49 | KCNA1 | potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218] | 27253 | -0.025 | -0.6316 | No |
| 50 | TEK | TEK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11724] | 28170 | -0.141 | -0.6557 | No |
| 51 | BLVRB | biliverdin reductase B [Source:HGNC Symbol;Acc:HGNC:1063] | 28844 | -0.234 | -0.6726 | No |
| 52 | PCOLCE | procollagen C-endopeptidase enhancer [Source:HGNC Symbol;Acc:HGNC:8738] | 29408 | -0.314 | -0.6862 | No |
| 53 | ANAPC11 | anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452] | 29624 | -0.343 | -0.6902 | No |
| 54 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 30241 | -0.434 | -0.7046 | No |
| 55 | MRGPRF | MAS related GPR family member F [Source:HGNC Symbol;Acc:HGNC:24828] | 30250 | -0.435 | -0.7025 | No |
| 56 | FBLN5 | fibulin 5 [Source:HGNC Symbol;Acc:HGNC:3602] | 30367 | -0.452 | -0.7033 | No |
| 57 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 30477 | -0.467 | -0.7038 | No |
| 58 | MFGE8 | milk fat globule EGF and factor V/VIII domain containing [Source:HGNC Symbol;Acc:HGNC:7036] | 30716 | -0.509 | -0.7075 | No |
| 59 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 30731 | -0.511 | -0.7052 | No |
| 60 | DYNLT1 | dynein light chain Tctex-type 1 [Source:HGNC Symbol;Acc:HGNC:11697] | 30932 | -0.546 | -0.7077 | No |
| 61 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 31053 | -0.567 | -0.7080 | No |
| 62 | TCFL5 | transcription factor like 5 [Source:HGNC Symbol;Acc:HGNC:11646] | 31165 | -0.583 | -0.7079 | No |
| 63 | CDH11 | cadherin 11 [Source:HGNC Symbol;Acc:HGNC:1750] | 31756 | -0.699 | -0.7202 | No |
| 64 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 32236 | -0.816 | -0.7288 | Yes |
| 65 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 32355 | -0.847 | -0.7275 | Yes |
| 66 | PTMA | prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623] | 32391 | -0.857 | -0.7239 | Yes |
| 67 | SAMD10 | sterile alpha motif domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16129] | 32605 | -0.905 | -0.7249 | Yes |
| 68 | NELFE | negative elongation factor complex member E [Source:HGNC Symbol;Acc:HGNC:13974] | 32643 | -0.915 | -0.7211 | Yes |
| 69 | PIDD1 | p53-induced death domain protein 1 [Source:HGNC Symbol;Acc:HGNC:16491] | 32826 | -0.969 | -0.7209 | Yes |
| 70 | NAA40 | N-alpha-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845] | 32993 | -1.013 | -0.7200 | Yes |
| 71 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 33196 | -1.074 | -0.7198 | Yes |
| 72 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33245 | -1.087 | -0.7154 | Yes |
| 73 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33258 | -1.093 | -0.7100 | Yes |
| 74 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 33394 | -1.135 | -0.7076 | Yes |
| 75 | ORC6 | origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151] | 33625 | -1.210 | -0.7074 | Yes |
| 76 | HEXD | hexosaminidase D [Source:HGNC Symbol;Acc:HGNC:26307] | 33945 | -1.322 | -0.7091 | Yes |
| 77 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 34079 | -1.367 | -0.7055 | Yes |
| 78 | IPO9 | importin 9 [Source:HGNC Symbol;Acc:HGNC:19425] | 34093 | -1.372 | -0.6986 | Yes |
| 79 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 34151 | -1.393 | -0.6928 | Yes |
| 80 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 34301 | -1.457 | -0.6891 | Yes |
| 81 | DCLRE1A | DNA cross-link repair 1A [Source:HGNC Symbol;Acc:HGNC:17660] | 34325 | -1.469 | -0.6820 | Yes |
| 82 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 34333 | -1.473 | -0.6744 | Yes |
| 83 | GINS4 | GINS complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:28226] | 34732 | -1.640 | -0.6765 | Yes |
| 84 | PRIM2 | DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370] | 34784 | -1.663 | -0.6691 | Yes |
| 85 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 34857 | -1.696 | -0.6621 | Yes |
| 86 | RPA2 | replication protein A2 [Source:HGNC Symbol;Acc:HGNC:10290] | 34954 | -1.749 | -0.6554 | Yes |
| 87 | FANCA | FA complementation group A [Source:HGNC Symbol;Acc:HGNC:3582] | 35160 | -1.856 | -0.6512 | Yes |
| 88 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 35328 | -1.964 | -0.6453 | Yes |
| 89 | ETHE1 | ETHE1 persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287] | 35586 | -2.145 | -0.6409 | Yes |
| 90 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35614 | -2.167 | -0.6302 | Yes |
| 91 | RHEBL1 | RHEB like 1 [Source:HGNC Symbol;Acc:HGNC:21166] | 35757 | -2.285 | -0.6220 | Yes |
| 92 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 35868 | -2.378 | -0.6124 | Yes |
| 93 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 35923 | -2.431 | -0.6010 | Yes |
| 94 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35937 | -2.441 | -0.5885 | Yes |
| 95 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 35965 | -2.473 | -0.5762 | Yes |
| 96 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36000 | -2.501 | -0.5639 | Yes |
| 97 | PAQR4 | progestin and adipoQ receptor family member 4 [Source:HGNC Symbol;Acc:HGNC:26386] | 36057 | -2.550 | -0.5519 | Yes |
| 98 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36076 | -2.578 | -0.5388 | Yes |
| 99 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 36081 | -2.586 | -0.5252 | Yes |
| 100 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36099 | -2.607 | -0.5119 | Yes |
| 101 | TRPM1 | transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146] | 36113 | -2.620 | -0.4984 | Yes |
| 102 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36139 | -2.657 | -0.4851 | Yes |
| 103 | POLE | DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177] | 36213 | -2.732 | -0.4726 | Yes |
| 104 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 36266 | -2.780 | -0.4593 | Yes |
| 105 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36303 | -2.820 | -0.4454 | Yes |
| 106 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 36346 | -2.873 | -0.4314 | Yes |
| 107 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36371 | -2.891 | -0.4168 | Yes |
| 108 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36425 | -2.957 | -0.4026 | Yes |
| 109 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36491 | -3.015 | -0.3884 | Yes |
| 110 | RFC2 | replication factor C subunit 2 [Source:HGNC Symbol;Acc:HGNC:9970] | 36566 | -3.117 | -0.3740 | Yes |
| 111 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36591 | -3.140 | -0.3580 | Yes |
| 112 | TCF19 | transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11629] | 36597 | -3.152 | -0.3415 | Yes |
| 113 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36606 | -3.169 | -0.3250 | Yes |
| 114 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36622 | -3.191 | -0.3085 | Yes |
| 115 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 36650 | -3.229 | -0.2922 | Yes |
| 116 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36667 | -3.270 | -0.2754 | Yes |
| 117 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36680 | -3.288 | -0.2583 | Yes |
| 118 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 36737 | -3.406 | -0.2419 | Yes |
| 119 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36857 | -3.648 | -0.2258 | Yes |
| 120 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 36862 | -3.659 | -0.2066 | Yes |
| 121 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36863 | -3.662 | -0.1872 | Yes |
| 122 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36891 | -3.747 | -0.1682 | Yes |
| 123 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36931 | -3.886 | -0.1487 | Yes |
| 124 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36949 | -3.950 | -0.1283 | Yes |
| 125 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36964 | -3.986 | -0.1076 | Yes |
| 126 | WDHD1 | WD repeat and HMG-box DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23170] | 36968 | -3.994 | -0.0866 | Yes |
| 127 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 36984 | -4.057 | -0.0656 | Yes |
| 128 | VEGFB | vascular endothelial growth factor B [Source:HGNC Symbol;Acc:HGNC:12681] | 37000 | -4.143 | -0.0441 | Yes |
| 129 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 37033 | -4.339 | -0.0221 | Yes |
| 130 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 37055 | -4.466 | 0.0009 | Yes |
