Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | RB_P130_DN.V1_UP |
| Enrichment Score (ES) | -0.62952995 |
| Normalized Enrichment Score (NES) | -1.332609 |
| Nominal p-value | 0.02181025 |
| FDR q-value | 0.1511501 |
| FWER p-Value | 0.923 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RGS16 | regulator of G protein signaling 16 [Source:HGNC Symbol;Acc:HGNC:9997] | 95 | 4.128 | 0.0282 | No |
| 2 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 106 | 4.064 | 0.0581 | No |
| 3 | HMGA2 | high mobility group AT-hook 2 [Source:HGNC Symbol;Acc:HGNC:5009] | 324 | 2.907 | 0.0739 | No |
| 4 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 758 | 1.886 | 0.0762 | No |
| 5 | LITAF | lipopolysaccharide induced TNF factor [Source:HGNC Symbol;Acc:HGNC:16841] | 921 | 1.640 | 0.0841 | No |
| 6 | QTRT1 | queuine tRNA-ribosyltransferase catalytic subunit 1 [Source:HGNC Symbol;Acc:HGNC:23797] | 1102 | 1.473 | 0.0902 | No |
| 7 | PPP1R15B | protein phosphatase 1 regulatory subunit 15B [Source:HGNC Symbol;Acc:HGNC:14951] | 1215 | 1.378 | 0.0974 | No |
| 8 | ATP2A1 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 [Source:HGNC Symbol;Acc:HGNC:811] | 1609 | 1.113 | 0.0950 | No |
| 9 | COL11A2 | collagen type XI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2187] | 2069 | 0.890 | 0.0892 | No |
| 10 | FST | follistatin [Source:HGNC Symbol;Acc:HGNC:3971] | 2427 | 0.759 | 0.0852 | No |
| 11 | TRAF2 | TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032] | 2449 | 0.750 | 0.0903 | No |
| 12 | SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 [Source:HGNC Symbol;Acc:HGNC:11153] | 2970 | 0.585 | 0.0805 | No |
| 13 | CASP7 | caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508] | 3386 | 0.485 | 0.0729 | No |
| 14 | ZBTB17 | zinc finger and BTB domain containing 17 [Source:HGNC Symbol;Acc:HGNC:12936] | 3456 | 0.470 | 0.0746 | No |
| 15 | RASA4 | RAS p21 protein activator 4 [Source:HGNC Symbol;Acc:HGNC:23181] | 3885 | 0.382 | 0.0658 | No |
| 16 | EFTUD2 | elongation factor Tu GTP binding domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30858] | 4333 | 0.297 | 0.0559 | No |
| 17 | MIGA2 | mitoguardin 2 [Source:HGNC Symbol;Acc:HGNC:23621] | 4521 | 0.265 | 0.0529 | No |
| 18 | RIPK3 | receptor interacting serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:10021] | 4632 | 0.247 | 0.0517 | No |
| 19 | MYLK | myosin light chain kinase [Source:HGNC Symbol;Acc:HGNC:7590] | 4839 | 0.215 | 0.0477 | No |
| 20 | CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 [Source:HGNC Symbol;Acc:HGNC:28314] | 5171 | 0.166 | 0.0400 | No |
| 21 | LSM4 | LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17259] | 5196 | 0.162 | 0.0406 | No |
| 22 | RASD1 | ras related dexamethasone induced 1 [Source:HGNC Symbol;Acc:HGNC:15828] | 5437 | 0.129 | 0.0350 | No |
| 23 | GC | GC vitamin D binding protein [Source:HGNC Symbol;Acc:HGNC:4187] | 5472 | 0.124 | 0.0350 | No |
| 24 | RHOJ | ras homolog family member J [Source:HGNC Symbol;Acc:HGNC:688] | 5952 | 0.061 | 0.0225 | No |
| 25 | TAL2 | TAL bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11557] | 6143 | 0.032 | 0.0176 | No |
| 26 | C11orf71 | chromosome 11 open reading frame 71 [Source:HGNC Symbol;Acc:HGNC:25937] | 6412 | 0.000 | 0.0104 | No |
| 27 | VSIG2 | V-set and immunoglobulin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:17149] | 6520 | 0.000 | 0.0075 | No |
| 28 | MYOZ2 | myozenin 2 [Source:HGNC Symbol;Acc:HGNC:1330] | 6523 | 0.000 | 0.0074 | No |
| 29 | USP13 | ubiquitin specific peptidase 13 [Source:HGNC Symbol;Acc:HGNC:12611] | 6624 | 0.000 | 0.0047 | No |
| 30 | FGF10 | fibroblast growth factor 10 [Source:HGNC Symbol;Acc:HGNC:3666] | 6926 | 0.000 | -0.0034 | No |
| 31 | AQP5 | aquaporin 5 [Source:HGNC Symbol;Acc:HGNC:638] | 7078 | 0.000 | -0.0075 | No |
| 32 | ART1 | ADP-ribosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:723] | 7460 | 0.000 | -0.0178 | No |
| 33 | GREM2 | gremlin 2, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:17655] | 8216 | 0.000 | -0.0382 | No |
| 34 | SIM1 | SIM bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10882] | 8356 | 0.000 | -0.0420 | No |
| 35 | SIM2 | SIM bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:10883] | 8357 | 0.000 | -0.0420 | No |
| 36 | B4GALT4 | beta-1,4-galactosyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:927] | 9628 | 0.000 | -0.0764 | No |
| 37 | PIWIL1 | piwi like RNA-mediated gene silencing 1 [Source:HGNC Symbol;Acc:HGNC:9007] | 9810 | 0.000 | -0.0812 | No |
| 38 | SLC22A3 | solute carrier family 22 member 3 [Source:HGNC Symbol;Acc:HGNC:10967] | 10171 | 0.000 | -0.0910 | No |
| 39 | FAM187A | family with sequence similarity 187 member A [Source:HGNC Symbol;Acc:HGNC:35153] | 10776 | 0.000 | -0.1073 | No |
| 40 | CRLF1 | cytokine receptor like factor 1 [Source:HGNC Symbol;Acc:HGNC:2364] | 10886 | 0.000 | -0.1103 | No |
| 41 | NKD2 | NKD inhibitor of WNT signaling pathway 2 [Source:HGNC Symbol;Acc:HGNC:17046] | 11217 | 0.000 | -0.1192 | No |
| 42 | PDZK1 | PDZ domain containing 1 [Source:HGNC Symbol;Acc:HGNC:8821] | 11299 | 0.000 | -0.1214 | No |
| 43 | NXNL1 | nucleoredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:25179] | 14726 | 0.000 | -0.2141 | No |
| 44 | PCSK5 | proprotein convertase subtilisin/kexin type 5 [Source:HGNC Symbol;Acc:HGNC:8747] | 16224 | 0.000 | -0.2546 | No |
| 45 | SLC7A9 | solute carrier family 7 member 9 [Source:HGNC Symbol;Acc:HGNC:11067] | 16686 | 0.000 | -0.2671 | No |
| 46 | TEAD1 | TEA domain transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11714] | 17060 | 0.000 | -0.2772 | No |
| 47 | TWIST2 | twist family bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:20670] | 17150 | 0.000 | -0.2796 | No |
| 48 | TINAG | tubulointerstitial nephritis antigen [Source:HGNC Symbol;Acc:HGNC:14599] | 17182 | 0.000 | -0.2804 | No |
| 49 | KAZN | kazrin, periplakin interacting protein [Source:HGNC Symbol;Acc:HGNC:29173] | 17274 | 0.000 | -0.2829 | No |
| 50 | SEMA5B | semaphorin 5B [Source:HGNC Symbol;Acc:HGNC:10737] | 17725 | 0.000 | -0.2950 | No |
| 51 | NKX2-8 | NK2 homeobox 8 [Source:HGNC Symbol;Acc:HGNC:16364] | 19035 | 0.000 | -0.3304 | No |
| 52 | PF4 | platelet factor 4 [Source:HGNC Symbol;Acc:HGNC:8861] | 19839 | 0.000 | -0.3522 | No |
| 53 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 20482 | 0.000 | -0.3695 | No |
| 54 | RSPH9 | radial spoke head component 9 [Source:HGNC Symbol;Acc:HGNC:21057] | 22129 | 0.000 | -0.4141 | No |
| 55 | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1 [Source:HGNC Symbol;Acc:HGNC:9875] | 22645 | 0.000 | -0.4280 | No |
| 56 | FOXI1 | forkhead box I1 [Source:HGNC Symbol;Acc:HGNC:3815] | 23329 | 0.000 | -0.4465 | No |
| 57 | NPPB | natriuretic peptide B [Source:HGNC Symbol;Acc:HGNC:7940] | 23403 | 0.000 | -0.4485 | No |
| 58 | SULT1B1 | sulfotransferase family 1B member 1 [Source:HGNC Symbol;Acc:HGNC:17845] | 23770 | 0.000 | -0.4584 | No |
| 59 | CRB3 | crumbs cell polarity complex component 3 [Source:HGNC Symbol;Acc:HGNC:20237] | 23851 | 0.000 | -0.4605 | No |
| 60 | WNT2B | Wnt family member 2B [Source:HGNC Symbol;Acc:HGNC:12781] | 24505 | 0.000 | -0.4782 | No |
| 61 | SPATA13 | spermatogenesis associated 13 [Source:HGNC Symbol;Acc:HGNC:23222] | 24737 | 0.000 | -0.4844 | No |
| 62 | STMN3 | stathmin 3 [Source:HGNC Symbol;Acc:HGNC:15926] | 26718 | 0.000 | -0.5380 | No |
| 63 | ALK | ALK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:427] | 26888 | 0.000 | -0.5426 | No |
| 64 | AVP | arginine vasopressin [Source:HGNC Symbol;Acc:HGNC:894] | 27050 | 0.000 | -0.5469 | No |
| 65 | EXOSC2 | exosome component 2 [Source:HGNC Symbol;Acc:HGNC:17097] | 27314 | -0.038 | -0.5538 | No |
| 66 | SLC13A2 | solute carrier family 13 member 2 [Source:HGNC Symbol;Acc:HGNC:10917] | 28226 | -0.149 | -0.5773 | No |
| 67 | GPN3 | GPN-loop GTPase 3 [Source:HGNC Symbol;Acc:HGNC:30186] | 28654 | -0.206 | -0.5873 | No |
| 68 | SNN | stannin [Source:HGNC Symbol;Acc:HGNC:11149] | 28705 | -0.214 | -0.5871 | No |
| 69 | GLIS2 | GLIS family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:29450] | 28898 | -0.241 | -0.5905 | No |
| 70 | ZNF428 | zinc finger protein 428 [Source:HGNC Symbol;Acc:HGNC:20804] | 29242 | -0.287 | -0.5976 | No |
| 71 | CRTAC1 | cartilage acidic protein 1 [Source:HGNC Symbol;Acc:HGNC:14882] | 29276 | -0.292 | -0.5964 | No |
| 72 | HINT1 | histidine triad nucleotide binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4912] | 29494 | -0.323 | -0.5998 | No |
| 73 | FAM220A | family with sequence similarity 220 member A [Source:HGNC Symbol;Acc:HGNC:22422] | 29616 | -0.341 | -0.6006 | No |
| 74 | CYBA | cytochrome b-245 alpha chain [Source:HGNC Symbol;Acc:HGNC:2577] | 29776 | -0.364 | -0.6021 | No |
| 75 | DUSP13 | dual specificity phosphatase 13 [Source:HGNC Symbol;Acc:HGNC:19681] | 30135 | -0.418 | -0.6087 | No |
| 76 | MBD3 | methyl-CpG binding domain protein 3 [Source:HGNC Symbol;Acc:HGNC:6918] | 30165 | -0.423 | -0.6064 | No |
| 77 | STAT5B | signal transducer and activator of transcription 5B [Source:HGNC Symbol;Acc:HGNC:11367] | 30827 | -0.529 | -0.6203 | No |
| 78 | RENBP | renin binding protein [Source:HGNC Symbol;Acc:HGNC:9959] | 30849 | -0.532 | -0.6169 | No |
| 79 | CMTM7 | CKLF like MARVEL transmembrane domain containing 7 [Source:HGNC Symbol;Acc:HGNC:19178] | 31230 | -0.594 | -0.6228 | No |
| 80 | ELOF1 | elongation factor 1 homolog [Source:HGNC Symbol;Acc:HGNC:28691] | 31481 | -0.642 | -0.6247 | Yes |
| 81 | RUVBL2 | RuvB like AAA ATPase 2 [Source:HGNC Symbol;Acc:HGNC:10475] | 31546 | -0.657 | -0.6216 | Yes |
| 82 | RGL3 | ral guanine nucleotide dissociation stimulator like 3 [Source:HGNC Symbol;Acc:HGNC:30282] | 31570 | -0.663 | -0.6173 | Yes |
| 83 | SDF2L1 | stromal cell derived factor 2 like 1 [Source:HGNC Symbol;Acc:HGNC:10676] | 31728 | -0.693 | -0.6164 | Yes |
| 84 | ORC1 | origin recognition complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:8487] | 31790 | -0.713 | -0.6127 | Yes |
| 85 | MRAS | muscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227] | 31897 | -0.736 | -0.6101 | Yes |
| 86 | EIF1B | eukaryotic translation initiation factor 1B [Source:HGNC Symbol;Acc:HGNC:30792] | 32267 | -0.823 | -0.6140 | Yes |
| 87 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 32439 | -0.866 | -0.6121 | Yes |
| 88 | PARS2 | prolyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:30563] | 32788 | -0.960 | -0.6144 | Yes |
| 89 | CARD19 | caspase recruitment domain family member 19 [Source:HGNC Symbol;Acc:HGNC:28148] | 32892 | -0.986 | -0.6098 | Yes |
| 90 | CHCHD6 | coiled-coil-helix-coiled-coil-helix domain containing 6 [Source:HGNC Symbol;Acc:HGNC:28184] | 32921 | -0.995 | -0.6032 | Yes |
| 91 | POLR2I | RNA polymerase II subunit I [Source:HGNC Symbol;Acc:HGNC:9196] | 32981 | -1.009 | -0.5973 | Yes |
| 92 | RABEPK | Rab9 effector protein with kelch motifs [Source:HGNC Symbol;Acc:HGNC:16896] | 33002 | -1.017 | -0.5902 | Yes |
| 93 | CUEDC2 | CUE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28352] | 33379 | -1.132 | -0.5920 | Yes |
| 94 | ERG | ETS transcription factor ERG [Source:HGNC Symbol;Acc:HGNC:3446] | 33466 | -1.158 | -0.5857 | Yes |
| 95 | ANAPC5 | anaphase promoting complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:15713] | 33626 | -1.210 | -0.5810 | Yes |
| 96 | MYG1 | MYG1 exonuclease [Source:HGNC Symbol;Acc:HGNC:17590] | 33795 | -1.268 | -0.5761 | Yes |
| 97 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33887 | -1.300 | -0.5689 | Yes |
| 98 | CDC7 | cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745] | 34380 | -1.492 | -0.5711 | Yes |
| 99 | RAD51D | RAD51 paralog D [Source:HGNC Symbol;Acc:HGNC:9823] | 34425 | -1.512 | -0.5610 | Yes |
| 100 | GFER | growth factor, augmenter of liver regeneration [Source:HGNC Symbol;Acc:HGNC:4236] | 34696 | -1.626 | -0.5562 | Yes |
| 101 | SLC43A3 | solute carrier family 43 member 3 [Source:HGNC Symbol;Acc:HGNC:17466] | 34808 | -1.676 | -0.5468 | Yes |
| 102 | COQ8A | coenzyme Q8A [Source:HGNC Symbol;Acc:HGNC:16812] | 34873 | -1.704 | -0.5358 | Yes |
| 103 | NSMCE1 | NSE1 homolog, SMC5-SMC6 complex component [Source:HGNC Symbol;Acc:HGNC:29897] | 34933 | -1.735 | -0.5245 | Yes |
| 104 | ENKD1 | enkurin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25246] | 35357 | -1.984 | -0.5212 | Yes |
| 105 | ABCG4 | ATP binding cassette subfamily G member 4 [Source:HGNC Symbol;Acc:HGNC:13884] | 35406 | -2.016 | -0.5074 | Yes |
| 106 | SELENOH | selenoprotein H [Source:HGNC Symbol;Acc:HGNC:18251] | 35610 | -2.161 | -0.4968 | Yes |
| 107 | OXLD1 | oxidoreductase like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27901] | 35655 | -2.203 | -0.4816 | Yes |
| 108 | POLD2 | DNA polymerase delta 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9176] | 35708 | -2.242 | -0.4664 | Yes |
| 109 | SGSM3 | small G protein signaling modulator 3 [Source:HGNC Symbol;Acc:HGNC:25228] | 35790 | -2.307 | -0.4514 | Yes |
| 110 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35816 | -2.333 | -0.4347 | Yes |
| 111 | SEMA6B | semaphorin 6B [Source:HGNC Symbol;Acc:HGNC:10739] | 35835 | -2.347 | -0.4177 | Yes |
| 112 | PIMREG | PICALM interacting mitotic regulator [Source:HGNC Symbol;Acc:HGNC:25483] | 36059 | -2.552 | -0.4047 | Yes |
| 113 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 36227 | -2.746 | -0.3888 | Yes |
| 114 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36279 | -2.795 | -0.3694 | Yes |
| 115 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36304 | -2.820 | -0.3490 | Yes |
| 116 | ICA1 | islet cell autoantigen 1 [Source:HGNC Symbol;Acc:HGNC:5343] | 36397 | -2.922 | -0.3298 | Yes |
| 117 | HYAL3 | hyaluronidase 3 [Source:HGNC Symbol;Acc:HGNC:5322] | 36475 | -2.999 | -0.3095 | Yes |
| 118 | FADS2 | fatty acid desaturase 2 [Source:HGNC Symbol;Acc:HGNC:3575] | 36575 | -3.127 | -0.2889 | Yes |
| 119 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36630 | -3.207 | -0.2665 | Yes |
| 120 | TRAF4 | TNF receptor associated factor 4 [Source:HGNC Symbol;Acc:HGNC:12034] | 36668 | -3.273 | -0.2431 | Yes |
| 121 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 36692 | -3.321 | -0.2190 | Yes |
| 122 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003] | 36790 | -3.513 | -0.1955 | Yes |
| 123 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36811 | -3.559 | -0.1696 | Yes |
| 124 | GRTP1 | growth hormone regulated TBC protein 1 [Source:HGNC Symbol;Acc:HGNC:20310] | 36817 | -3.573 | -0.1431 | Yes |
| 125 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36833 | -3.603 | -0.1167 | Yes |
| 126 | ZBTB12 | zinc finger and BTB domain containing 12 [Source:HGNC Symbol;Acc:HGNC:19066] | 36848 | -3.629 | -0.0900 | Yes |
| 127 | ATP2A3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 [Source:HGNC Symbol;Acc:HGNC:813] | 36941 | -3.914 | -0.0634 | Yes |
| 128 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37060 | -4.490 | -0.0332 | Yes |
| 129 | SNTA1 | syntrophin alpha 1 [Source:HGNC Symbol;Acc:HGNC:11167] | 37066 | -4.559 | 0.0006 | Yes |
