Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | DESCARTES_FETAL_SPLEEN_MYELOID_CELLS |
| Enrichment Score (ES) | 0.6010525 |
| Normalized Enrichment Score (NES) | 1.6053535 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.06128535 |
| FWER p-Value | 0.295 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 4 | 4.962 | 0.0439 | Yes |
| 2 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 12 | 4.922 | 0.0874 | Yes |
| 3 | MNDA | myeloid cell nuclear differentiation antigen [Source:HGNC Symbol;Acc:HGNC:7183] | 36 | 4.719 | 0.1286 | Yes |
| 4 | KCNAB1 | potassium voltage-gated channel subfamily A member regulatory beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:6228] | 47 | 4.613 | 0.1693 | Yes |
| 5 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 48 | 4.592 | 0.2100 | Yes |
| 6 | NLRP3 | NLR family pyrin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:16400] | 90 | 4.161 | 0.2458 | Yes |
| 7 | SIGLEC1 | sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127] | 108 | 4.052 | 0.2813 | Yes |
| 8 | OSM | oncostatin M [Source:HGNC Symbol;Acc:HGNC:8506] | 138 | 3.873 | 0.3149 | Yes |
| 9 | RGS1 | regulator of G protein signaling 1 [Source:HGNC Symbol;Acc:HGNC:9991] | 164 | 3.689 | 0.3469 | Yes |
| 10 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 213 | 3.401 | 0.3758 | Yes |
| 11 | HCK | HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] | 229 | 3.311 | 0.4047 | Yes |
| 12 | ADAP2 | ArfGAP with dual PH domains 2 [Source:HGNC Symbol;Acc:HGNC:16487] | 252 | 3.226 | 0.4328 | Yes |
| 13 | RAB20 | RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260] | 284 | 3.081 | 0.4593 | Yes |
| 14 | NABP1 | nucleic acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:26232] | 356 | 2.749 | 0.4817 | Yes |
| 15 | IL10 | interleukin 10 [Source:HGNC Symbol;Acc:HGNC:5962] | 377 | 2.677 | 0.5049 | Yes |
| 16 | THEMIS2 | thymocyte selection associated family member 2 [Source:HGNC Symbol;Acc:HGNC:16839] | 608 | 2.134 | 0.5176 | Yes |
| 17 | RASSF4 | Ras association domain family member 4 [Source:HGNC Symbol;Acc:HGNC:20793] | 615 | 2.123 | 0.5363 | Yes |
| 18 | NOD2 | nucleotide binding oligomerization domain containing 2 [Source:HGNC Symbol;Acc:HGNC:5331] | 746 | 1.903 | 0.5497 | Yes |
| 19 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 755 | 1.889 | 0.5662 | Yes |
| 20 | CD274 | CD274 molecule [Source:HGNC Symbol;Acc:HGNC:17635] | 982 | 1.579 | 0.5741 | Yes |
| 21 | PID1 | phosphotyrosine interaction domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26084] | 1066 | 1.497 | 0.5851 | Yes |
| 22 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 1267 | 1.338 | 0.5916 | Yes |
| 23 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 1607 | 1.113 | 0.5923 | Yes |
| 24 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 1724 | 1.043 | 0.5984 | Yes |
| 25 | LY96 | lymphocyte antigen 96 [Source:HGNC Symbol;Acc:HGNC:17156] | 1948 | 0.938 | 0.6007 | Yes |
| 26 | ITGAX | integrin subunit alpha X [Source:HGNC Symbol;Acc:HGNC:6152] | 2209 | 0.833 | 0.6011 | Yes |
| 27 | NAIP | NLR family apoptosis inhibitory protein [Source:HGNC Symbol;Acc:HGNC:7634] | 2533 | 0.725 | 0.5987 | No |
| 28 | SMIM35 | small integral membrane protein 35 [Source:HGNC Symbol;Acc:HGNC:44179] | 2817 | 0.632 | 0.5967 | No |
| 29 | NCF2 | neutrophil cytosolic factor 2 [Source:HGNC Symbol;Acc:HGNC:7661] | 3084 | 0.561 | 0.5945 | No |
| 30 | FCGR1A | Fc fragment of IgG receptor Ia [Source:HGNC Symbol;Acc:HGNC:3613] | 3513 | 0.458 | 0.5870 | No |
| 31 | ITGAD | integrin subunit alpha D [Source:HGNC Symbol;Acc:HGNC:6146] | 3598 | 0.440 | 0.5886 | No |
| 32 | CD200R1 | CD200 receptor 1 [Source:HGNC Symbol;Acc:HGNC:24235] | 3707 | 0.418 | 0.5894 | No |
| 33 | ADGRE1 | adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336] | 4004 | 0.359 | 0.5846 | No |
| 34 | GHRL | ghrelin and obestatin prepropeptide [Source:HGNC Symbol;Acc:HGNC:18129] | 4340 | 0.297 | 0.5781 | No |
| 35 | CABP4 | calcium binding protein 4 [Source:HGNC Symbol;Acc:HGNC:1386] | 4622 | 0.248 | 0.5727 | No |
| 36 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 4623 | 0.248 | 0.5749 | No |
| 37 | HRH1 | histamine receptor H1 [Source:HGNC Symbol;Acc:HGNC:5182] | 4884 | 0.209 | 0.5697 | No |
| 38 | RAB39A | RAB39A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16521] | 5580 | 0.112 | 0.5519 | No |
| 39 | IL10RA | interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964] | 6317 | 0.007 | 0.5321 | No |
| 40 | FAM20A | FAM20A golgi associated secretory pathway pseudokinase [Source:HGNC Symbol;Acc:HGNC:23015] | 6328 | 0.005 | 0.5319 | No |
| 41 | VSIG4 | V-set and immunoglobulin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:17032] | 6522 | 0.000 | 0.5266 | No |
| 42 | LINC01645 | long intergenic non-protein coding RNA 1645 [Source:HGNC Symbol;Acc:HGNC:52432] | 7274 | 0.000 | 0.5063 | No |
| 43 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 7733 | 0.000 | 0.4939 | No |
| 44 | EPB41L3 | erythrocyte membrane protein band 4.1 like 3 [Source:HGNC Symbol;Acc:HGNC:3380] | 8000 | 0.000 | 0.4867 | No |
| 45 | RASGEF1C | RasGEF domain family member 1C [Source:HGNC Symbol;Acc:HGNC:27400] | 8205 | 0.000 | 0.4812 | No |
| 46 | FCAR | Fc fragment of IgA receptor [Source:HGNC Symbol;Acc:HGNC:3608] | 8304 | 0.000 | 0.4786 | No |
| 47 | FCN1 | ficolin 1 [Source:HGNC Symbol;Acc:HGNC:3623] | 8378 | 0.000 | 0.4766 | No |
| 48 | AL606970.3 | novel transcript | 8383 | 0.000 | 0.4765 | No |
| 49 | BATF3 | basic leucine zipper ATF-like transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:28915] | 8824 | 0.000 | 0.4646 | No |
| 50 | CLEC7A | C-type lectin domain containing 7A [Source:HGNC Symbol;Acc:HGNC:14558] | 9485 | 0.000 | 0.4467 | No |
| 51 | ADGRE4P | adhesion G protein-coupled receptor E4, pseudogene [Source:HGNC Symbol;Acc:HGNC:19240] | 10554 | 0.000 | 0.4178 | No |
| 52 | CHN2 | chimerin 2 [Source:HGNC Symbol;Acc:HGNC:1944] | 10619 | 0.000 | 0.4161 | No |
| 53 | IGSF21 | immunoglobin superfamily member 21 [Source:HGNC Symbol;Acc:HGNC:28246] | 10899 | 0.000 | 0.4086 | No |
| 54 | MS4A7 | membrane spanning 4-domains A7 [Source:HGNC Symbol;Acc:HGNC:13378] | 11035 | 0.000 | 0.4049 | No |
| 55 | S100Z | S100 calcium binding protein Z [Source:HGNC Symbol;Acc:HGNC:30367] | 11617 | 0.000 | 0.3892 | No |
| 56 | CLNK | cytokine dependent hematopoietic cell linker [Source:HGNC Symbol;Acc:HGNC:17438] | 11619 | 0.000 | 0.3892 | No |
| 57 | SIGLEC16 | sialic acid binding Ig like lectin 16 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:24851] | 11821 | 0.000 | 0.3837 | No |
| 58 | CSF2RA | colony stimulating factor 2 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:2435] | 11896 | 0.000 | 0.3817 | No |
| 59 | AGR2 | anterior gradient 2, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:328] | 12040 | 0.000 | 0.3779 | No |
| 60 | LINC00996 | long intergenic non-protein coding RNA 996 [Source:HGNC Symbol;Acc:HGNC:27800] | 12042 | 0.000 | 0.3778 | No |
| 61 | TGFA | transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765] | 12441 | 0.000 | 0.3671 | No |
| 62 | LILRA5 | leukocyte immunoglobulin like receptor A5 [Source:HGNC Symbol;Acc:HGNC:16309] | 13388 | 0.000 | 0.3415 | No |
| 63 | LILRB1 | leukocyte immunoglobulin like receptor B1 [Source:HGNC Symbol;Acc:HGNC:6605] | 13392 | 0.000 | 0.3414 | No |
| 64 | LILRB2 | leukocyte immunoglobulin like receptor B2 [Source:HGNC Symbol;Acc:HGNC:6606] | 13393 | 0.000 | 0.3414 | No |
| 65 | LILRB3 | leukocyte immunoglobulin like receptor B3 [Source:HGNC Symbol;Acc:HGNC:6607] | 13394 | 0.000 | 0.3414 | No |
| 66 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13395 | 0.000 | 0.3414 | No |
| 67 | LILRB5 | leukocyte immunoglobulin like receptor B5 [Source:HGNC Symbol;Acc:HGNC:6609] | 13396 | 0.000 | 0.3414 | No |
| 68 | MEGF11 | multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635] | 14264 | 0.000 | 0.3179 | No |
| 69 | EBI3 | Epstein-Barr virus induced 3 [Source:HGNC Symbol;Acc:HGNC:3129] | 14930 | 0.000 | 0.2999 | No |
| 70 | ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 [Source:HGNC Symbol;Acc:HGNC:3357] | 15669 | 0.000 | 0.2800 | No |
| 71 | CD300LF | CD300 molecule like family member f [Source:HGNC Symbol;Acc:HGNC:29883] | 15815 | 0.000 | 0.2761 | No |
| 72 | IL1R2 | interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994] | 15869 | 0.000 | 0.2746 | No |
| 73 | NEXMIF | neurite extension and migration factor [Source:HGNC Symbol;Acc:HGNC:29433] | 16023 | 0.000 | 0.2705 | No |
| 74 | TIMD4 | T cell immunoglobulin and mucin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25132] | 16205 | 0.000 | 0.2656 | No |
| 75 | TMEM63C | transmembrane protein 63C [Source:HGNC Symbol;Acc:HGNC:23787] | 18152 | 0.000 | 0.2129 | No |
| 76 | RN7SL138P | RNA, 7SL, cytoplasmic 138, pseudogene [Source:HGNC Symbol;Acc:HGNC:46154] | 18262 | 0.000 | 0.2100 | No |
| 77 | MRO | maestro [Source:HGNC Symbol;Acc:HGNC:24121] | 18912 | 0.000 | 0.1924 | No |
| 78 | RUFY4 | RUN and FYVE domain containing 4 [Source:HGNC Symbol;Acc:HGNC:24804] | 20027 | 0.000 | 0.1623 | No |
| 79 | IDO1 | indoleamine 2,3-dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:6059] | 20032 | 0.000 | 0.1622 | No |
| 80 | CMKLR1 | chemerin chemokine-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:2121] | 22156 | 0.000 | 0.1048 | No |
| 81 | DSCAM-IT1 | DSCAM intronic transcript 1 [Source:HGNC Symbol;Acc:HGNC:41327] | 22414 | 0.000 | 0.0978 | No |
| 82 | CLEC9A | C-type lectin domain containing 9A [Source:HGNC Symbol;Acc:HGNC:26705] | 22765 | 0.000 | 0.0883 | No |
| 83 | CD163L1 | CD163 molecule like 1 [Source:HGNC Symbol;Acc:HGNC:30375] | 23694 | 0.000 | 0.0632 | No |
| 84 | SIGLEC7 | sialic acid binding Ig like lectin 7 [Source:HGNC Symbol;Acc:HGNC:10876] | 23848 | 0.000 | 0.0591 | No |
| 85 | NRIR | negative regulator of interferon response [Source:HGNC Symbol;Acc:HGNC:51269] | 23915 | 0.000 | 0.0573 | No |
| 86 | ADGRE2 | adhesion G protein-coupled receptor E2 [Source:HGNC Symbol;Acc:HGNC:3337] | 24089 | 0.000 | 0.0526 | No |
| 87 | EYA2 | EYA transcriptional coactivator and phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3520] | 24139 | 0.000 | 0.0513 | No |
| 88 | NCKAP5 | NCK associated protein 5 [Source:HGNC Symbol;Acc:HGNC:29847] | 24153 | 0.000 | 0.0509 | No |
| 89 | PDCD1LG2 | programmed cell death 1 ligand 2 [Source:HGNC Symbol;Acc:HGNC:18731] | 25228 | 0.000 | 0.0219 | No |
| 90 | CCDC170 | coiled-coil domain containing 170 [Source:HGNC Symbol;Acc:HGNC:21177] | 25641 | 0.000 | 0.0107 | No |
| 91 | MS4A4E | membrane spanning 4-domains A4E [Source:HGNC Symbol;Acc:HGNC:14284] | 25686 | 0.000 | 0.0096 | No |
| 92 | MS4A4A | membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371] | 25691 | 0.000 | 0.0094 | No |
| 93 | MS4A6A | membrane spanning 4-domains A6A [Source:HGNC Symbol;Acc:HGNC:13375] | 25698 | 0.000 | 0.0093 | No |
| 94 | SPIC | Spi-C transcription factor [Source:HGNC Symbol;Acc:HGNC:29549] | 25987 | 0.000 | 0.0015 | No |
| 95 | OSCAR | osteoclast associated Ig-like receptor [Source:HGNC Symbol;Acc:HGNC:29960] | 26671 | 0.000 | -0.0170 | No |
| 96 | SIRPB2 | signal regulatory protein beta 2 [Source:HGNC Symbol;Acc:HGNC:16247] | 26686 | 0.000 | -0.0174 | No |
| 97 | DSCAM | DS cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:3039] | 27067 | 0.000 | -0.0276 | No |
| 98 | MERTK | MER proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:7027] | 28358 | -0.166 | -0.0611 | No |
| 99 | FMN1 | formin 1 [Source:HGNC Symbol;Acc:HGNC:3768] | 28363 | -0.167 | -0.0597 | No |
| 100 | PPARG | peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236] | 28404 | -0.172 | -0.0593 | No |
| 101 | FABP5 | fatty acid binding protein 5 [Source:HGNC Symbol;Acc:HGNC:3560] | 29051 | -0.261 | -0.0744 | No |
| 102 | KCNMA1 | potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284] | 29111 | -0.269 | -0.0736 | No |
| 103 | IGSF6 | immunoglobulin superfamily member 6 [Source:HGNC Symbol;Acc:HGNC:5953] | 29130 | -0.272 | -0.0717 | No |
| 104 | ANKRD24 | ankyrin repeat domain 24 [Source:HGNC Symbol;Acc:HGNC:29424] | 29691 | -0.353 | -0.0837 | No |
| 105 | ZNF415P1 | zinc finger protein 415 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49869] | 30217 | -0.431 | -0.0941 | No |
| 106 | CARD14 | caspase recruitment domain family member 14 [Source:HGNC Symbol;Acc:HGNC:16446] | 31097 | -0.574 | -0.1128 | No |
| 107 | FLVCR2 | FLVCR heme transporter 2 [Source:HGNC Symbol;Acc:HGNC:20105] | 31229 | -0.594 | -0.1111 | No |
| 108 | TRIM36 | tripartite motif containing 36 [Source:HGNC Symbol;Acc:HGNC:16280] | 31276 | -0.603 | -0.1070 | No |
| 109 | HK3 | hexokinase 3 [Source:HGNC Symbol;Acc:HGNC:4925] | 31300 | -0.607 | -0.1022 | No |
| 110 | MKNK1 | MAPK interacting serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:7110] | 31339 | -0.614 | -0.0978 | No |
| 111 | RGL3 | ral guanine nucleotide dissociation stimulator like 3 [Source:HGNC Symbol;Acc:HGNC:30282] | 31570 | -0.663 | -0.0981 | No |
| 112 | PRAM1 | PML-RARA regulated adaptor molecule 1 [Source:HGNC Symbol;Acc:HGNC:30091] | 31723 | -0.693 | -0.0961 | No |
| 113 | ALMS1P1 | ALMS1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:29586] | 32275 | -0.825 | -0.1037 | No |
| 114 | DMXL2 | Dmx like 2 [Source:HGNC Symbol;Acc:HGNC:2938] | 32327 | -0.839 | -0.0976 | No |
| 115 | GPR137B | G protein-coupled receptor 137B [Source:HGNC Symbol;Acc:HGNC:11862] | 32820 | -0.968 | -0.1023 | No |
| 116 | CDS1 | CDP-diacylglycerol synthase 1 [Source:HGNC Symbol;Acc:HGNC:1800] | 32961 | -1.003 | -0.0972 | No |
| 117 | TRPV4 | transient receptor potential cation channel subfamily V member 4 [Source:HGNC Symbol;Acc:HGNC:18083] | 34268 | -1.442 | -0.1198 | No |
| 118 | LYZ | lysozyme [Source:HGNC Symbol;Acc:HGNC:6740] | 34592 | -1.578 | -0.1145 | No |
| 119 | ZNF710 | zinc finger protein 710 [Source:HGNC Symbol;Acc:HGNC:25352] | 34616 | -1.590 | -0.1010 | No |
| 120 | MCOLN1 | mucolipin 1 [Source:HGNC Symbol;Acc:HGNC:13356] | 34753 | -1.649 | -0.0901 | No |
| 121 | KCNK13 | potassium two pore domain channel subfamily K member 13 [Source:HGNC Symbol;Acc:HGNC:6275] | 35044 | -1.792 | -0.0820 | No |
| 122 | LRRK1 | leucine rich repeat kinase 1 [Source:HGNC Symbol;Acc:HGNC:18608] | 35368 | -1.993 | -0.0731 | No |
| 123 | SIRPB1 | signal regulatory protein beta 1 [Source:HGNC Symbol;Acc:HGNC:15928] | 35849 | -2.359 | -0.0652 | No |
| 124 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 36694 | -3.323 | -0.0585 | No |
| 125 | WWP1 | WW domain containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:17004] | 36915 | -3.811 | -0.0307 | No |
| 126 | SLC8A1 | solute carrier family 8 member A1 [Source:HGNC Symbol;Acc:HGNC:11068] | 36966 | -3.986 | 0.0034 | No |
