Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | TRAVAGLINI_LUNG_MUCOUS_CELL |
| Enrichment Score (ES) | 0.6302071 |
| Normalized Enrichment Score (NES) | 1.6600217 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.06399283 |
| FWER p-Value | 0.175 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 1 | 4.975 | 0.0478 | Yes |
| 2 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 13 | 4.920 | 0.0949 | Yes |
| 3 | DUSP5 | dual specificity phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:3071] | 16 | 4.904 | 0.1420 | Yes |
| 4 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 48 | 4.592 | 0.1853 | Yes |
| 5 | CPD | carboxypeptidase D [Source:HGNC Symbol;Acc:HGNC:2301] | 87 | 4.177 | 0.2245 | Yes |
| 6 | ASS1 | argininosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:758] | 91 | 4.153 | 0.2644 | Yes |
| 7 | PLK2 | polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699] | 147 | 3.806 | 0.2995 | Yes |
| 8 | CFB | complement factor B [Source:HGNC Symbol;Acc:HGNC:1037] | 182 | 3.590 | 0.3331 | Yes |
| 9 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 221 | 3.363 | 0.3644 | Yes |
| 10 | SAA1 | serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513] | 259 | 3.209 | 0.3943 | Yes |
| 11 | LYN | LYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6735] | 341 | 2.816 | 0.4192 | Yes |
| 12 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 419 | 2.554 | 0.4417 | Yes |
| 13 | SAA2 | serum amyloid A2 [Source:HGNC Symbol;Acc:HGNC:10514] | 430 | 2.523 | 0.4657 | Yes |
| 14 | C15orf48 | chromosome 15 open reading frame 48 [Source:HGNC Symbol;Acc:HGNC:29898] | 537 | 2.273 | 0.4847 | Yes |
| 15 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 722 | 1.944 | 0.4984 | Yes |
| 16 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 732 | 1.930 | 0.5167 | Yes |
| 17 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 872 | 1.694 | 0.5293 | Yes |
| 18 | PDZK1IP1 | PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887] | 874 | 1.693 | 0.5455 | Yes |
| 19 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 949 | 1.612 | 0.5590 | Yes |
| 20 | TNIP3 | TNFAIP3 interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:19315] | 984 | 1.578 | 0.5733 | Yes |
| 21 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 1156 | 1.433 | 0.5824 | Yes |
| 22 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 1226 | 1.371 | 0.5938 | Yes |
| 23 | TGM2 | transglutaminase 2 [Source:HGNC Symbol;Acc:HGNC:11778] | 1424 | 1.228 | 0.6002 | Yes |
| 24 | REEP3 | receptor accessory protein 3 [Source:HGNC Symbol;Acc:HGNC:23711] | 1457 | 1.204 | 0.6110 | Yes |
| 25 | ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10862] | 1735 | 1.039 | 0.6135 | Yes |
| 26 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 1800 | 1.011 | 0.6215 | Yes |
| 27 | C3 | complement C3 [Source:HGNC Symbol;Acc:HGNC:1318] | 2058 | 0.892 | 0.6231 | Yes |
| 28 | MED24 | mediator complex subunit 24 [Source:HGNC Symbol;Acc:HGNC:22963] | 2107 | 0.875 | 0.6302 | Yes |
| 29 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 2780 | 0.644 | 0.6182 | No |
| 30 | MDK | midkine [Source:HGNC Symbol;Acc:HGNC:6972] | 3580 | 0.445 | 0.6009 | No |
| 31 | TMEM165 | transmembrane protein 165 [Source:HGNC Symbol;Acc:HGNC:30760] | 3711 | 0.417 | 0.6014 | No |
| 32 | BID | BH3 interacting domain death agonist [Source:HGNC Symbol;Acc:HGNC:1050] | 3879 | 0.384 | 0.6006 | No |
| 33 | RDH10 | retinol dehydrogenase 10 [Source:HGNC Symbol;Acc:HGNC:19975] | 4281 | 0.305 | 0.5926 | No |
| 34 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 5152 | 0.168 | 0.5707 | No |
| 35 | RASD1 | ras related dexamethasone induced 1 [Source:HGNC Symbol;Acc:HGNC:15828] | 5437 | 0.129 | 0.5643 | No |
| 36 | KDR | kinase insert domain receptor [Source:HGNC Symbol;Acc:HGNC:6307] | 6136 | 0.033 | 0.5457 | No |
| 37 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6434 | 0.000 | 0.5377 | No |
| 38 | MUCL1 | mucin like 1 [Source:HGNC Symbol;Acc:HGNC:30588] | 6525 | 0.000 | 0.5353 | No |
| 39 | DEFB4A | defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767] | 7195 | 0.000 | 0.5172 | No |
| 40 | WFDC2 | WAP four-disulfide core domain 2 [Source:HGNC Symbol;Acc:HGNC:15939] | 8135 | 0.000 | 0.4918 | No |
| 41 | PROM1 | prominin 1 [Source:HGNC Symbol;Acc:HGNC:9454] | 8246 | 0.000 | 0.4888 | No |
| 42 | S100A9 | S100 calcium binding protein A9 [Source:HGNC Symbol;Acc:HGNC:10499] | 8520 | 0.000 | 0.4814 | No |
| 43 | CRISP3 | cysteine rich secretory protein 3 [Source:HGNC Symbol;Acc:HGNC:16904] | 9067 | 0.000 | 0.4666 | No |
| 44 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 9164 | 0.000 | 0.4640 | No |
| 45 | SLPI | secretory leukocyte peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:11092] | 9248 | 0.000 | 0.4618 | No |
| 46 | GPX3 | glutathione peroxidase 3 [Source:HGNC Symbol;Acc:HGNC:4555] | 9497 | 0.000 | 0.4551 | No |
| 47 | ADAM28 | ADAM metallopeptidase domain 28 [Source:HGNC Symbol;Acc:HGNC:206] | 9723 | 0.000 | 0.4490 | No |
| 48 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 10000 | 0.000 | 0.4415 | No |
| 49 | CYP2F1 | cytochrome P450 family 2 subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:2632] | 10356 | 0.000 | 0.4319 | No |
| 50 | KLK10 | kallikrein related peptidase 10 [Source:HGNC Symbol;Acc:HGNC:6358] | 10456 | 0.000 | 0.4292 | No |
| 51 | KLK11 | kallikrein related peptidase 11 [Source:HGNC Symbol;Acc:HGNC:6359] | 10457 | 0.000 | 0.4292 | No |
| 52 | KLK12 | kallikrein related peptidase 12 [Source:HGNC Symbol;Acc:HGNC:6360] | 10458 | 0.000 | 0.4292 | No |
| 53 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10724 | 0.000 | 0.4221 | No |
| 54 | LCN2 | lipocalin 2 [Source:HGNC Symbol;Acc:HGNC:6526] | 10905 | 0.000 | 0.4172 | No |
| 55 | SLC26A4 | solute carrier family 26 member 4 [Source:HGNC Symbol;Acc:HGNC:8818] | 11138 | 0.000 | 0.4109 | No |
| 56 | TSPAN8 | tetraspanin 8 [Source:HGNC Symbol;Acc:HGNC:11855] | 11472 | 0.000 | 0.4019 | No |
| 57 | AKR1C1 | aldo-keto reductase family 1 member C1 [Source:HGNC Symbol;Acc:HGNC:384] | 11510 | 0.000 | 0.4009 | No |
| 58 | AKR1C2 | aldo-keto reductase family 1 member C2 [Source:HGNC Symbol;Acc:HGNC:385] | 11512 | 0.000 | 0.4009 | No |
| 59 | S100P | S100 calcium binding protein P [Source:HGNC Symbol;Acc:HGNC:10504] | 11620 | 0.000 | 0.3980 | No |
| 60 | BACE2 | beta-secretase 2 [Source:HGNC Symbol;Acc:HGNC:934] | 11680 | 0.000 | 0.3964 | No |
| 61 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 11730 | 0.000 | 0.3951 | No |
| 62 | MSMB | microseminoprotein beta [Source:HGNC Symbol;Acc:HGNC:7372] | 12392 | 0.000 | 0.3772 | No |
| 63 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12430 | 0.000 | 0.3762 | No |
| 64 | VMO1 | vitelline membrane outer layer 1 homolog [Source:HGNC Symbol;Acc:HGNC:30387] | 12473 | 0.000 | 0.3751 | No |
| 65 | MUC4 | mucin 4, cell surface associated [Source:HGNC Symbol;Acc:HGNC:7514] | 12795 | 0.000 | 0.3664 | No |
| 66 | LINC00342 | long intergenic non-protein coding RNA 342 [Source:HGNC Symbol;Acc:HGNC:42470] | 12981 | 0.000 | 0.3614 | No |
| 67 | ZG16B | zymogen granule protein 16B [Source:HGNC Symbol;Acc:HGNC:30456] | 13245 | 0.000 | 0.3542 | No |
| 68 | TMC5 | transmembrane channel like 5 [Source:HGNC Symbol;Acc:HGNC:22999] | 14353 | 0.000 | 0.3243 | No |
| 69 | TMEM45A | transmembrane protein 45A [Source:HGNC Symbol;Acc:HGNC:25480] | 14692 | 0.000 | 0.3152 | No |
| 70 | CDC42EP5 | CDC42 effector protein 5 [Source:HGNC Symbol;Acc:HGNC:17408] | 16118 | 0.000 | 0.2766 | No |
| 71 | BPIFA1 | BPI fold containing family A member 1 [Source:HGNC Symbol;Acc:HGNC:15749] | 17493 | 0.000 | 0.2394 | No |
| 72 | BPIFB1 | BPI fold containing family B member 1 [Source:HGNC Symbol;Acc:HGNC:16108] | 17540 | 0.000 | 0.2382 | No |
| 73 | ANKRD36C | ankyrin repeat domain 36C [Source:HGNC Symbol;Acc:HGNC:32946] | 17732 | 0.000 | 0.2330 | No |
| 74 | HILPDA | hypoxia inducible lipid droplet associated [Source:HGNC Symbol;Acc:HGNC:28859] | 17777 | 0.000 | 0.2318 | No |
| 75 | HLA-DQA2 | major histocompatibility complex, class II, DQ alpha 2 [Source:HGNC Symbol;Acc:HGNC:4943] | 18274 | 0.000 | 0.2184 | No |
| 76 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18275 | 0.000 | 0.2184 | No |
| 77 | LTF | lactotransferrin [Source:HGNC Symbol;Acc:HGNC:6720] | 18608 | 0.000 | 0.2094 | No |
| 78 | MMP7 | matrix metallopeptidase 7 [Source:HGNC Symbol;Acc:HGNC:7174] | 18961 | 0.000 | 0.1999 | No |
| 79 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19304 | 0.000 | 0.1907 | No |
| 80 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19309 | 0.000 | 0.1906 | No |
| 81 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19318 | 0.000 | 0.1903 | No |
| 82 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19320 | 0.000 | 0.1903 | No |
| 83 | SMIM31 | small integral membrane protein 31 [Source:HGNC Symbol;Acc:HGNC:49638] | 19570 | 0.000 | 0.1836 | No |
| 84 | HSD17B2 | hydroxysteroid 17-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5211] | 19632 | 0.000 | 0.1819 | No |
| 85 | PI3 | peptidase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:8947] | 19855 | 0.000 | 0.1759 | No |
| 86 | IDO1 | indoleamine 2,3-dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:6059] | 20032 | 0.000 | 0.1712 | No |
| 87 | TFF3 | trefoil factor 3 [Source:HGNC Symbol;Acc:HGNC:11757] | 20536 | 0.000 | 0.1576 | No |
| 88 | KYNU | kynureninase [Source:HGNC Symbol;Acc:HGNC:6469] | 21812 | 0.000 | 0.1231 | No |
| 89 | PIGR | polymeric immunoglobulin receptor [Source:HGNC Symbol;Acc:HGNC:8968] | 22535 | 0.000 | 0.1035 | No |
| 90 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22684 | 0.000 | 0.0995 | No |
| 91 | SCGB3A1 | secretoglobin family 3A member 1 [Source:HGNC Symbol;Acc:HGNC:18384] | 23259 | 0.000 | 0.0840 | No |
| 92 | SCGB1A1 | secretoglobin family 1A member 1 [Source:HGNC Symbol;Acc:HGNC:12523] | 23933 | 0.000 | 0.0658 | No |
| 93 | RARRES1 | retinoic acid receptor responder 1 [Source:HGNC Symbol;Acc:HGNC:9867] | 24067 | 0.000 | 0.0622 | No |
| 94 | CRYM | crystallin mu [Source:HGNC Symbol;Acc:HGNC:2418] | 24135 | 0.000 | 0.0604 | No |
| 95 | MUC5B | mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:HGNC:7516] | 24143 | 0.000 | 0.0602 | No |
| 96 | TFPI2 | tissue factor pathway inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:11761] | 24672 | 0.000 | 0.0459 | No |
| 97 | SLC4A4 | solute carrier family 4 member 4 [Source:HGNC Symbol;Acc:HGNC:11030] | 24984 | 0.000 | 0.0375 | No |
| 98 | RIMS1 | regulating synaptic membrane exocytosis 1 [Source:HGNC Symbol;Acc:HGNC:17282] | 25057 | 0.000 | 0.0356 | No |
| 99 | ALDH1A3 | aldehyde dehydrogenase 1 family member A3 [Source:HGNC Symbol;Acc:HGNC:409] | 25324 | 0.000 | 0.0284 | No |
| 100 | AZGP1 | alpha-2-glycoprotein 1, zinc-binding [Source:HGNC Symbol;Acc:HGNC:910] | 26328 | 0.000 | 0.0012 | No |
| 101 | FCGBP | Fc fragment of IgG binding protein [Source:HGNC Symbol;Acc:HGNC:13572] | 26395 | 0.000 | -0.0006 | No |
| 102 | XBP1 | X-box binding protein 1 [Source:HGNC Symbol;Acc:HGNC:12801] | 27305 | -0.035 | -0.0248 | No |
| 103 | ATP12A | ATPase H+/K+ transporting non-gastric alpha2 subunit [Source:HGNC Symbol;Acc:HGNC:13816] | 27428 | -0.052 | -0.0276 | No |
| 104 | SRD5A3 | steroid 5 alpha-reductase 3 [Source:HGNC Symbol;Acc:HGNC:25812] | 27906 | -0.110 | -0.0395 | No |
| 105 | SLC5A5 | solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040] | 28166 | -0.141 | -0.0451 | No |
| 106 | IRAK3 | interleukin 1 receptor associated kinase 3 [Source:HGNC Symbol;Acc:HGNC:17020] | 28304 | -0.157 | -0.0473 | No |
| 107 | CSTB | cystatin B [Source:HGNC Symbol;Acc:HGNC:2482] | 28612 | -0.201 | -0.0537 | No |
| 108 | RHOV | ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313] | 29121 | -0.271 | -0.0648 | No |
| 109 | LAG3 | lymphocyte activating 3 [Source:HGNC Symbol;Acc:HGNC:6476] | 29380 | -0.310 | -0.0688 | No |
| 110 | ANPEP | alanyl aminopeptidase, membrane [Source:HGNC Symbol;Acc:HGNC:500] | 29628 | -0.344 | -0.0722 | No |
| 111 | SLC26A2 | solute carrier family 26 member 2 [Source:HGNC Symbol;Acc:HGNC:10994] | 30054 | -0.405 | -0.0798 | No |
| 112 | CP | ceruloplasmin [Source:HGNC Symbol;Acc:HGNC:2295] | 30058 | -0.406 | -0.0760 | No |
| 113 | DUSP23 | dual specificity phosphatase 23 [Source:HGNC Symbol;Acc:HGNC:21480] | 30657 | -0.499 | -0.0873 | No |
| 114 | HIPK2 | homeodomain interacting protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:14402] | 30704 | -0.506 | -0.0837 | No |
| 115 | RPS26 | ribosomal protein S26 [Source:HGNC Symbol;Acc:HGNC:10414] | 31532 | -0.653 | -0.0998 | No |
| 116 | CTSB | cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527] | 31922 | -0.743 | -0.1032 | No |
| 117 | STT3B | STT3 oligosaccharyltransferase complex catalytic subunit B [Source:HGNC Symbol;Acc:HGNC:30611] | 34210 | -1.414 | -0.1514 | No |
| 118 | ERO1A | endoplasmic reticulum oxidoreductase 1 alpha [Source:HGNC Symbol;Acc:HGNC:13280] | 35421 | -2.027 | -0.1647 | No |
| 119 | ADM | adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259] | 36003 | -2.504 | -0.1563 | No |
| 120 | SLC9A3R2 | SLC9A3 regulator 2 [Source:HGNC Symbol;Acc:HGNC:11076] | 36145 | -2.660 | -0.1345 | No |
| 121 | INSR | insulin receptor [Source:HGNC Symbol;Acc:HGNC:6091] | 36416 | -2.949 | -0.1135 | No |
| 122 | SORD | sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184] | 36574 | -3.127 | -0.0876 | No |
| 123 | CBR3 | carbonyl reductase 3 [Source:HGNC Symbol;Acc:HGNC:1549] | 36594 | -3.142 | -0.0579 | No |
| 124 | PTP4A3 | protein tyrosine phosphatase 4A3 [Source:HGNC Symbol;Acc:HGNC:9636] | 36707 | -3.354 | -0.0287 | No |
| 125 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 36984 | -4.057 | 0.0029 | No |
