Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | ZHONG_PFC_C2_UNKNOWN_NPC |
| Enrichment Score (ES) | -0.8921476 |
| Normalized Enrichment Score (NES) | -1.8027941 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1902 | 0.962 | -0.0460 | No |
| 2 | CNOT7 | CCR4-NOT transcription complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:14101] | 2494 | 0.736 | -0.0579 | No |
| 3 | CALB2 | calbindin 2 [Source:HGNC Symbol;Acc:HGNC:1435] | 3829 | 0.395 | -0.0917 | No |
| 4 | KDM4A | lysine demethylase 4A [Source:HGNC Symbol;Acc:HGNC:22978] | 6059 | 0.044 | -0.1517 | No |
| 5 | AC091057.1 | OTU deubiquitinase 7A pseudogene [Source:NCBI gene (formerly Entrezgene);Acc:100288637] | 12783 | 0.000 | -0.3333 | No |
| 6 | NDST4 | N-deacetylase and N-sulfotransferase 4 [Source:HGNC Symbol;Acc:HGNC:20779] | 13472 | 0.000 | -0.3519 | No |
| 7 | DNALI1 | dynein axonemal light intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:14353] | 17753 | 0.000 | -0.4675 | No |
| 8 | ZNF649 | zinc finger protein 649 [Source:HGNC Symbol;Acc:HGNC:25741] | 21187 | 0.000 | -0.5603 | No |
| 9 | AMBN | ameloblastin [Source:HGNC Symbol;Acc:HGNC:452] | 24292 | 0.000 | -0.6441 | No |
| 10 | MFAP2 | microfibril associated protein 2 [Source:HGNC Symbol;Acc:HGNC:7033] | 25152 | 0.000 | -0.6673 | No |
| 11 | ITCH | itchy E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13890] | 28651 | -0.206 | -0.7607 | No |
| 12 | TUBB6 | tubulin beta 6 class V [Source:HGNC Symbol;Acc:HGNC:20776] | 29054 | -0.261 | -0.7701 | No |
| 13 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29215 | -0.283 | -0.7728 | No |
| 14 | PRR11 | proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] | 31394 | -0.626 | -0.8281 | No |
| 15 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 31585 | -0.666 | -0.8296 | No |
| 16 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 33447 | -1.152 | -0.8734 | No |
| 17 | ARL6IP1 | ADP ribosylation factor like GTPase 6 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:697] | 33885 | -1.299 | -0.8779 | No |
| 18 | TROAP | trophinin associated protein [Source:HGNC Symbol;Acc:HGNC:12327] | 34306 | -1.460 | -0.8811 | No |
| 19 | G2E3 | G2/M-phase specific E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:20338] | 34441 | -1.517 | -0.8763 | No |
| 20 | LDHA | lactate dehydrogenase A [Source:HGNC Symbol;Acc:HGNC:6535] | 35030 | -1.784 | -0.8822 | Yes |
| 21 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 35063 | -1.804 | -0.8730 | Yes |
| 22 | ARHGAP11A | Rho GTPase activating protein 11A [Source:HGNC Symbol;Acc:HGNC:15783] | 35215 | -1.897 | -0.8664 | Yes |
| 23 | RANGAP1 | Ran GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9854] | 35245 | -1.916 | -0.8565 | Yes |
| 24 | DEPDC1 | DEP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22949] | 35388 | -2.006 | -0.8491 | Yes |
| 25 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 35484 | -2.073 | -0.8401 | Yes |
| 26 | REEP4 | receptor accessory protein 4 [Source:HGNC Symbol;Acc:HGNC:26176] | 35544 | -2.109 | -0.8299 | Yes |
| 27 | MZT1 | mitotic spindle organizing protein 1 [Source:HGNC Symbol;Acc:HGNC:33830] | 35653 | -2.203 | -0.8205 | Yes |
| 28 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35717 | -2.250 | -0.8096 | Yes |
| 29 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 35735 | -2.266 | -0.7974 | Yes |
| 30 | NDE1 | nudE neurodevelopment protein 1 [Source:HGNC Symbol;Acc:HGNC:17619] | 35777 | -2.301 | -0.7857 | Yes |
| 31 | TUBA1C | tubulin alpha 1c [Source:HGNC Symbol;Acc:HGNC:20768] | 35782 | -2.303 | -0.7729 | Yes |
| 32 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35816 | -2.333 | -0.7608 | Yes |
| 33 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35837 | -2.347 | -0.7482 | Yes |
| 34 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 35899 | -2.411 | -0.7363 | Yes |
| 35 | SPDL1 | spindle apparatus coiled-coil protein 1 [Source:HGNC Symbol;Acc:HGNC:26010] | 35981 | -2.483 | -0.7246 | Yes |
| 36 | PHF19 | PHD finger protein 19 [Source:HGNC Symbol;Acc:HGNC:24566] | 36051 | -2.548 | -0.7123 | Yes |
| 37 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 36081 | -2.586 | -0.6986 | Yes |
| 38 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 36108 | -2.616 | -0.6847 | Yes |
| 39 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 36141 | -2.658 | -0.6707 | Yes |
| 40 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 36174 | -2.692 | -0.6565 | Yes |
| 41 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 36227 | -2.746 | -0.6426 | Yes |
| 42 | CIT | citron rho-interacting serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1985] | 36259 | -2.775 | -0.6279 | Yes |
| 43 | MIS18BP1 | MIS18 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:20190] | 36262 | -2.779 | -0.6124 | Yes |
| 44 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36279 | -2.795 | -0.5972 | Yes |
| 45 | CEP70 | centrosomal protein 70 [Source:HGNC Symbol;Acc:HGNC:29972] | 36295 | -2.815 | -0.5819 | Yes |
| 46 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36339 | -2.870 | -0.5670 | Yes |
| 47 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36376 | -2.899 | -0.5518 | Yes |
| 48 | TRIM59 | tripartite motif containing 59 [Source:HGNC Symbol;Acc:HGNC:30834] | 36428 | -2.961 | -0.5366 | Yes |
| 49 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36469 | -2.992 | -0.5209 | Yes |
| 50 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 36478 | -3.003 | -0.5044 | Yes |
| 51 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36483 | -3.006 | -0.4877 | Yes |
| 52 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36535 | -3.075 | -0.4719 | Yes |
| 53 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36592 | -3.140 | -0.4558 | Yes |
| 54 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 36605 | -3.169 | -0.4384 | Yes |
| 55 | FAM83D | family with sequence similarity 83 member D [Source:HGNC Symbol;Acc:HGNC:16122] | 36609 | -3.173 | -0.4208 | Yes |
| 56 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36630 | -3.207 | -0.4034 | Yes |
| 57 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 36650 | -3.229 | -0.3858 | Yes |
| 58 | CDCA2 | cell division cycle associated 2 [Source:HGNC Symbol;Acc:HGNC:14623] | 36673 | -3.282 | -0.3681 | Yes |
| 59 | CKAP2L | cytoskeleton associated protein 2 like [Source:HGNC Symbol;Acc:HGNC:26877] | 36687 | -3.310 | -0.3499 | Yes |
| 60 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 36692 | -3.321 | -0.3315 | Yes |
| 61 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36709 | -3.356 | -0.3132 | Yes |
| 62 | KNSTRN | kinetochore localized astrin (SPAG5) binding protein [Source:HGNC Symbol;Acc:HGNC:30767] | 36731 | -3.399 | -0.2947 | Yes |
| 63 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36811 | -3.559 | -0.2770 | Yes |
| 64 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36833 | -3.603 | -0.2574 | Yes |
| 65 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36868 | -3.675 | -0.2378 | Yes |
| 66 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36870 | -3.679 | -0.2172 | Yes |
| 67 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36882 | -3.715 | -0.1967 | Yes |
| 68 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36894 | -3.758 | -0.1760 | Yes |
| 69 | PIF1 | PIF1 5'-to-3' DNA helicase [Source:HGNC Symbol;Acc:HGNC:26220] | 36919 | -3.828 | -0.1553 | Yes |
| 70 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36922 | -3.842 | -0.1339 | Yes |
| 71 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36955 | -3.967 | -0.1125 | Yes |
| 72 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36964 | -3.986 | -0.0905 | Yes |
| 73 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36971 | -4.005 | -0.0683 | Yes |
| 74 | NEIL3 | nei like DNA glycosylase 3 [Source:HGNC Symbol;Acc:HGNC:24573] | 36996 | -4.111 | -0.0459 | Yes |
| 75 | PSRC1 | proline and serine rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:24472] | 37009 | -4.173 | -0.0229 | Yes |
| 76 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 37059 | -4.485 | 0.0008 | Yes |
