Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | HALLMARK_COAGULATION |
| Enrichment Score (ES) | 0.4163294 |
| Normalized Enrichment Score (NES) | 1.0935858 |
| Nominal p-value | 0.2159091 |
| FDR q-value | 0.24108756 |
| FWER p-Value | 0.576 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SERPINB2 | serpin family B member 2 [Source:HGNC Symbol;Acc:HGNC:8584] | 10 | 4.944 | 0.0476 | Yes |
| 2 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 54 | 4.518 | 0.0901 | Yes |
| 3 | SERPINE1 | serpin family E member 1 [Source:HGNC Symbol;Acc:HGNC:8583] | 177 | 3.605 | 0.1217 | Yes |
| 4 | CFB | complement factor B [Source:HGNC Symbol;Acc:HGNC:1037] | 182 | 3.590 | 0.1563 | Yes |
| 5 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 190 | 3.533 | 0.1903 | Yes |
| 6 | PLEK | pleckstrin [Source:HGNC Symbol;Acc:HGNC:9070] | 369 | 2.700 | 0.2116 | Yes |
| 7 | MMP2 | matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:7166] | 426 | 2.528 | 0.2346 | Yes |
| 8 | MAFF | MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780] | 459 | 2.451 | 0.2574 | Yes |
| 9 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 474 | 2.407 | 0.2803 | Yes |
| 10 | F9 | coagulation factor IX [Source:HGNC Symbol;Acc:HGNC:3551] | 552 | 2.235 | 0.2999 | Yes |
| 11 | SERPINC1 | serpin family C member 1 [Source:HGNC Symbol;Acc:HGNC:775] | 668 | 2.036 | 0.3165 | Yes |
| 12 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 722 | 1.944 | 0.3338 | Yes |
| 13 | WDR1 | WD repeat domain 1 [Source:HGNC Symbol;Acc:HGNC:12754] | 739 | 1.920 | 0.3520 | Yes |
| 14 | ANXA1 | annexin A1 [Source:HGNC Symbol;Acc:HGNC:533] | 1019 | 1.534 | 0.3593 | Yes |
| 15 | CD9 | CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709] | 1060 | 1.500 | 0.3727 | Yes |
| 16 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 1156 | 1.433 | 0.3840 | Yes |
| 17 | MMP14 | matrix metallopeptidase 14 [Source:HGNC Symbol;Acc:HGNC:7160] | 1512 | 1.169 | 0.3857 | Yes |
| 18 | FBN1 | fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603] | 1561 | 1.142 | 0.3955 | Yes |
| 19 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 1647 | 1.087 | 0.4037 | Yes |
| 20 | FYN | FYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4037] | 1770 | 1.022 | 0.4103 | Yes |
| 21 | C3 | complement C3 [Source:HGNC Symbol;Acc:HGNC:1318] | 2058 | 0.892 | 0.4111 | Yes |
| 22 | VWF | von Willebrand factor [Source:HGNC Symbol;Acc:HGNC:12726] | 2397 | 0.766 | 0.4094 | Yes |
| 23 | CTSV | cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538] | 2548 | 0.716 | 0.4123 | Yes |
| 24 | ARF4 | ADP ribosylation factor 4 [Source:HGNC Symbol;Acc:HGNC:655] | 2644 | 0.685 | 0.4163 | Yes |
| 25 | GNG12 | G protein subunit gamma 12 [Source:HGNC Symbol;Acc:HGNC:19663] | 3411 | 0.480 | 0.4002 | No |
| 26 | CTSO | cathepsin O [Source:HGNC Symbol;Acc:HGNC:2542] | 3446 | 0.471 | 0.4039 | No |
| 27 | KLF7 | Kruppel like factor 7 [Source:HGNC Symbol;Acc:HGNC:6350] | 3724 | 0.415 | 0.4004 | No |
| 28 | ITIH1 | inter-alpha-trypsin inhibitor heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:6166] | 3792 | 0.403 | 0.4025 | No |
| 29 | PREP | prolyl endopeptidase [Source:HGNC Symbol;Acc:HGNC:9358] | 4260 | 0.310 | 0.3928 | No |
| 30 | F3 | coagulation factor III, tissue factor [Source:HGNC Symbol;Acc:HGNC:3541] | 4431 | 0.282 | 0.3910 | No |
| 31 | RABIF | RAB interacting factor [Source:HGNC Symbol;Acc:HGNC:9797] | 4499 | 0.268 | 0.3918 | No |
| 32 | GNB2 | G protein subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:4398] | 4701 | 0.236 | 0.3886 | No |
| 33 | MMP10 | matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156] | 4847 | 0.214 | 0.3868 | No |
| 34 | BMP1 | bone morphogenetic protein 1 [Source:HGNC Symbol;Acc:HGNC:1067] | 4914 | 0.205 | 0.3870 | No |
| 35 | C2 | complement C2 [Source:HGNC Symbol;Acc:HGNC:1248] | 4983 | 0.193 | 0.3870 | No |
| 36 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 4987 | 0.192 | 0.3888 | No |
| 37 | LAMP2 | lysosomal associated membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:6501] | 5010 | 0.190 | 0.3900 | No |
| 38 | ADAM9 | ADAM metallopeptidase domain 9 [Source:HGNC Symbol;Acc:HGNC:216] | 5132 | 0.172 | 0.3884 | No |
| 39 | HTRA1 | HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HGNC:9476] | 5305 | 0.147 | 0.3852 | No |
| 40 | F10 | coagulation factor X [Source:HGNC Symbol;Acc:HGNC:3528] | 5422 | 0.130 | 0.3833 | No |
| 41 | SPARC | secreted protein acidic and cysteine rich [Source:HGNC Symbol;Acc:HGNC:11219] | 5558 | 0.114 | 0.3807 | No |
| 42 | MMP3 | matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173] | 5731 | 0.092 | 0.3770 | No |
| 43 | FN1 | fibronectin 1 [Source:HGNC Symbol;Acc:HGNC:3778] | 5802 | 0.082 | 0.3759 | No |
| 44 | ITGB3 | integrin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6156] | 6364 | 0.000 | 0.3607 | No |
| 45 | RAPGEF3 | Rap guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:16629] | 6691 | 0.000 | 0.3519 | No |
| 46 | PLAT | plasminogen activator, tissue type [Source:HGNC Symbol;Acc:HGNC:9051] | 9916 | 0.000 | 0.2646 | No |
| 47 | APOA1 | apolipoprotein A1 [Source:HGNC Symbol;Acc:HGNC:600] | 10124 | 0.000 | 0.2590 | No |
| 48 | APOC3 | apolipoprotein C3 [Source:HGNC Symbol;Acc:HGNC:610] | 10138 | 0.000 | 0.2587 | No |
| 49 | APOC2 | apolipoprotein C2 [Source:HGNC Symbol;Acc:HGNC:609] | 10140 | 0.000 | 0.2586 | No |
| 50 | APOC1 | apolipoprotein C1 [Source:HGNC Symbol;Acc:HGNC:607] | 10141 | 0.000 | 0.2586 | No |
| 51 | F13B | coagulation factor XIII B chain [Source:HGNC Symbol;Acc:HGNC:3534] | 10849 | 0.000 | 0.2395 | No |
| 52 | KLKB1 | kallikrein B1 [Source:HGNC Symbol;Acc:HGNC:6371] | 11110 | 0.000 | 0.2325 | No |
| 53 | TMPRSS6 | transmembrane serine protease 6 [Source:HGNC Symbol;Acc:HGNC:16517] | 11500 | 0.000 | 0.2220 | No |
| 54 | PROZ | protein Z, vitamin K dependent plasma glycoprotein [Source:HGNC Symbol;Acc:HGNC:9460] | 11547 | 0.000 | 0.2207 | No |
| 55 | PROC | protein C, inactivator of coagulation factors Va and VIIIa [Source:HGNC Symbol;Acc:HGNC:9451] | 11564 | 0.000 | 0.2203 | No |
| 56 | ACOX2 | acyl-CoA oxidase 2 [Source:HGNC Symbol;Acc:HGNC:120] | 12255 | 0.000 | 0.2016 | No |
| 57 | P2RY1 | purinergic receptor P2Y1 [Source:HGNC Symbol;Acc:HGNC:8539] | 14056 | 0.000 | 0.1529 | No |
| 58 | MBL2 | mannose binding lectin 2 [Source:HGNC Symbol;Acc:HGNC:6922] | 15587 | 0.000 | 0.1115 | No |
| 59 | C8B | complement C8 beta chain [Source:HGNC Symbol;Acc:HGNC:1353] | 15653 | 0.000 | 0.1097 | No |
| 60 | C8A | complement C8 alpha chain [Source:HGNC Symbol;Acc:HGNC:1352] | 15654 | 0.000 | 0.1097 | No |
| 61 | C8G | complement C8 gamma chain [Source:HGNC Symbol;Acc:HGNC:1354] | 15656 | 0.000 | 0.1097 | No |
| 62 | CFD | complement factor D [Source:HGNC Symbol;Acc:HGNC:2771] | 15753 | 0.000 | 0.1071 | No |
| 63 | CFI | complement factor I [Source:HGNC Symbol;Acc:HGNC:5394] | 15754 | 0.000 | 0.1071 | No |
| 64 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 15994 | 0.000 | 0.1006 | No |
| 65 | C9 | complement C9 [Source:HGNC Symbol;Acc:HGNC:1358] | 16069 | 0.000 | 0.0986 | No |
| 66 | F2 | coagulation factor II, thrombin [Source:HGNC Symbol;Acc:HGNC:3535] | 16113 | 0.000 | 0.0975 | No |
| 67 | F12 | coagulation factor XII [Source:HGNC Symbol;Acc:HGNC:3530] | 16403 | 0.000 | 0.0897 | No |
| 68 | F11 | coagulation factor XI [Source:HGNC Symbol;Acc:HGNC:3529] | 16404 | 0.000 | 0.0897 | No |
| 69 | FGA | fibrinogen alpha chain [Source:HGNC Symbol;Acc:HGNC:3661] | 16629 | 0.000 | 0.0836 | No |
| 70 | FGG | fibrinogen gamma chain [Source:HGNC Symbol;Acc:HGNC:3694] | 16630 | 0.000 | 0.0836 | No |
| 71 | OLR1 | oxidized low density lipoprotein receptor 1 [Source:HGNC Symbol;Acc:HGNC:8133] | 16676 | 0.000 | 0.0824 | No |
| 72 | GP9 | glycoprotein IX platelet [Source:HGNC Symbol;Acc:HGNC:4444] | 17052 | 0.000 | 0.0722 | No |
| 73 | TIMP3 | TIMP metallopeptidase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:11822] | 17059 | 0.000 | 0.0721 | No |
| 74 | HRG | histidine rich glycoprotein [Source:HGNC Symbol;Acc:HGNC:5181] | 17389 | 0.000 | 0.0632 | No |
| 75 | HNF4A | hepatocyte nuclear factor 4 alpha [Source:HGNC Symbol;Acc:HGNC:5024] | 17562 | 0.000 | 0.0585 | No |
| 76 | SERPING1 | serpin family G member 1 [Source:HGNC Symbol;Acc:HGNC:1228] | 17676 | 0.000 | 0.0554 | No |
| 77 | SERPINA1 | serpin family A member 1 [Source:HGNC Symbol;Acc:HGNC:8941] | 17687 | 0.000 | 0.0552 | No |
| 78 | DPP4 | dipeptidyl peptidase 4 [Source:HGNC Symbol;Acc:HGNC:3009] | 17829 | 0.000 | 0.0514 | No |
| 79 | MMP7 | matrix metallopeptidase 7 [Source:HGNC Symbol;Acc:HGNC:7174] | 18961 | 0.000 | 0.0208 | No |
| 80 | MMP1 | matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155] | 18964 | 0.000 | 0.0207 | No |
| 81 | MMP8 | matrix metallopeptidase 8 [Source:HGNC Symbol;Acc:HGNC:7175] | 18973 | 0.000 | 0.0205 | No |
| 82 | PF4 | platelet factor 4 [Source:HGNC Symbol;Acc:HGNC:8861] | 19839 | 0.000 | -0.0029 | No |
| 83 | HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 [Source:HGNC Symbol;Acc:HGNC:5008] | 19880 | 0.000 | -0.0040 | No |
| 84 | PLG | plasminogen [Source:HGNC Symbol;Acc:HGNC:9071] | 19913 | 0.000 | -0.0049 | No |
| 85 | C1QA | complement C1q A chain [Source:HGNC Symbol;Acc:HGNC:1241] | 19969 | 0.000 | -0.0064 | No |
| 86 | LEFTY2 | left-right determination factor 2 [Source:HGNC Symbol;Acc:HGNC:3122] | 20078 | 0.000 | -0.0093 | No |
| 87 | KLK8 | kallikrein related peptidase 8 [Source:HGNC Symbol;Acc:HGNC:6369] | 20511 | 0.000 | -0.0210 | No |
| 88 | MMP11 | matrix metallopeptidase 11 [Source:HGNC Symbol;Acc:HGNC:7157] | 20735 | 0.000 | -0.0270 | No |
| 89 | MMP15 | matrix metallopeptidase 15 [Source:HGNC Symbol;Acc:HGNC:7161] | 20740 | 0.000 | -0.0271 | No |
| 90 | F2RL2 | coagulation factor II thrombin receptor like 2 [Source:HGNC Symbol;Acc:HGNC:3539] | 20952 | 0.000 | -0.0328 | No |
| 91 | MEP1A | meprin A subunit alpha [Source:HGNC Symbol;Acc:HGNC:7015] | 22976 | 0.000 | -0.0876 | No |
| 92 | GP1BA | glycoprotein Ib platelet subunit alpha [Source:HGNC Symbol;Acc:HGNC:4439] | 23034 | 0.000 | -0.0891 | No |
| 93 | CPB2 | carboxypeptidase B2 [Source:HGNC Symbol;Acc:HGNC:2300] | 23210 | 0.000 | -0.0938 | No |
| 94 | TFPI2 | tissue factor pathway inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:11761] | 24672 | 0.000 | -0.1334 | No |
| 95 | PRSS23 | serine protease 23 [Source:HGNC Symbol;Acc:HGNC:14370] | 24937 | 0.000 | -0.1405 | No |
| 96 | ITGA2 | integrin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6137] | 26075 | 0.000 | -0.1713 | No |
| 97 | A2M | alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7] | 26618 | 0.000 | -0.1860 | No |
| 98 | RAC1 | Rac family small GTPase 1 [Source:HGNC Symbol;Acc:HGNC:9801] | 27366 | -0.044 | -0.2058 | No |
| 99 | THBD | thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784] | 27398 | -0.047 | -0.2061 | No |
| 100 | RGN | regucalcin [Source:HGNC Symbol;Acc:HGNC:9989] | 28106 | -0.134 | -0.2240 | No |
| 101 | CPN1 | carboxypeptidase N subunit 1 [Source:HGNC Symbol;Acc:HGNC:2312] | 28262 | -0.153 | -0.2267 | No |
| 102 | DUSP6 | dual specificity phosphatase 6 [Source:HGNC Symbol;Acc:HGNC:3072] | 28901 | -0.241 | -0.2416 | No |
| 103 | C1S | complement C1s [Source:HGNC Symbol;Acc:HGNC:1247] | 29570 | -0.335 | -0.2564 | No |
| 104 | HPN | hepsin [Source:HGNC Symbol;Acc:HGNC:5155] | 29933 | -0.388 | -0.2625 | No |
| 105 | MASP2 | mannan binding lectin serine peptidase 2 [Source:HGNC Symbol;Acc:HGNC:6902] | 30119 | -0.415 | -0.2635 | No |
| 106 | PEF1 | penta-EF-hand domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30009] | 30128 | -0.417 | -0.2597 | No |
| 107 | C1R | complement C1r [Source:HGNC Symbol;Acc:HGNC:1246] | 30614 | -0.493 | -0.2680 | No |
| 108 | S100A13 | S100 calcium binding protein A13 [Source:HGNC Symbol;Acc:HGNC:10490] | 31162 | -0.583 | -0.2772 | No |
| 109 | CTSK | cathepsin K [Source:HGNC Symbol;Acc:HGNC:2536] | 31355 | -0.616 | -0.2764 | No |
| 110 | MSRB2 | methionine sulfoxide reductase B2 [Source:HGNC Symbol;Acc:HGNC:17061] | 31497 | -0.646 | -0.2740 | No |
| 111 | MST1 | macrophage stimulating 1 [Source:HGNC Symbol;Acc:HGNC:7380] | 31511 | -0.648 | -0.2681 | No |
| 112 | SIRT2 | sirtuin 2 [Source:HGNC Symbol;Acc:HGNC:10886] | 31626 | -0.676 | -0.2646 | No |
| 113 | GDA | guanine deaminase [Source:HGNC Symbol;Acc:HGNC:4212] | 31648 | -0.680 | -0.2586 | No |
| 114 | F8 | coagulation factor VIII [Source:HGNC Symbol;Acc:HGNC:3546] | 31667 | -0.683 | -0.2525 | No |
| 115 | CTSB | cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527] | 31922 | -0.743 | -0.2521 | No |
| 116 | CTSE | cathepsin E [Source:HGNC Symbol;Acc:HGNC:2530] | 31972 | -0.756 | -0.2462 | No |
| 117 | CTSH | cathepsin H [Source:HGNC Symbol;Acc:HGNC:2535] | 32196 | -0.808 | -0.2444 | No |
| 118 | CRIP2 | cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361] | 33008 | -1.019 | -0.2565 | No |
| 119 | ISCU | iron-sulfur cluster assembly enzyme [Source:HGNC Symbol;Acc:HGNC:29882] | 33356 | -1.125 | -0.2550 | No |
| 120 | CASP9 | caspase 9 [Source:HGNC Symbol;Acc:HGNC:1511] | 33489 | -1.166 | -0.2473 | No |
| 121 | CPQ | carboxypeptidase Q [Source:HGNC Symbol;Acc:HGNC:16910] | 33579 | -1.195 | -0.2381 | No |
| 122 | SH2B2 | SH2B adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:17381] | 33705 | -1.237 | -0.2295 | No |
| 123 | PROS1 | protein S [Source:HGNC Symbol;Acc:HGNC:9456] | 33784 | -1.263 | -0.2194 | No |
| 124 | CAPN2 | calpain 2 [Source:HGNC Symbol;Acc:HGNC:1479] | 34158 | -1.395 | -0.2160 | No |
| 125 | S100A1 | S100 calcium binding protein A1 [Source:HGNC Symbol;Acc:HGNC:10486] | 34199 | -1.409 | -0.2034 | No |
| 126 | USP11 | ubiquitin specific peptidase 11 [Source:HGNC Symbol;Acc:HGNC:12609] | 34280 | -1.445 | -0.1916 | No |
| 127 | TF | transferrin [Source:HGNC Symbol;Acc:HGNC:11740] | 34452 | -1.522 | -0.1815 | No |
| 128 | CSRP1 | cysteine and glycine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:2469] | 34570 | -1.571 | -0.1695 | No |
| 129 | COMP | cartilage oligomeric matrix protein [Source:HGNC Symbol;Acc:HGNC:2227] | 35032 | -1.785 | -0.1647 | No |
| 130 | LTA4H | leukotriene A4 hydrolase [Source:HGNC Symbol;Acc:HGNC:6710] | 35232 | -1.905 | -0.1517 | No |
| 131 | CAPN5 | calpain 5 [Source:HGNC Symbol;Acc:HGNC:1482] | 35331 | -1.966 | -0.1353 | No |
| 132 | LRP1 | LDL receptor related protein 1 [Source:HGNC Symbol;Acc:HGNC:6692] | 35812 | -2.327 | -0.1258 | No |
| 133 | PLAU | plasminogen activator, urokinase [Source:HGNC Symbol;Acc:HGNC:9052] | 36385 | -2.909 | -0.1131 | No |
| 134 | GSN | gelsolin [Source:HGNC Symbol;Acc:HGNC:4620] | 36652 | -3.230 | -0.0890 | No |
| 135 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 36694 | -3.323 | -0.0580 | No |
| 136 | ANG | angiogenin [Source:HGNC Symbol;Acc:HGNC:483] | 36713 | -3.369 | -0.0259 | No |
| 137 | CFH | complement factor H [Source:HGNC Symbol;Acc:HGNC:4883] | 36888 | -3.726 | 0.0055 | No |
