Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | HALLMARK_INTERFERON_ALPHA_RESPONSE |
| Enrichment Score (ES) | 0.880686 |
| Normalized Enrichment Score (NES) | 2.2885575 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 6 | 4.960 | 0.0220 | Yes |
| 2 | GBP4 | guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480] | 14 | 4.909 | 0.0438 | Yes |
| 3 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 23 | 4.827 | 0.0652 | Yes |
| 4 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 24 | 4.813 | 0.0867 | Yes |
| 5 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 31 | 4.755 | 0.1078 | Yes |
| 6 | OASL | 2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] | 33 | 4.742 | 0.1290 | Yes |
| 7 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 46 | 4.625 | 0.1493 | Yes |
| 8 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 48 | 4.592 | 0.1698 | Yes |
| 9 | IFIH1 | interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873] | 53 | 4.525 | 0.1899 | Yes |
| 10 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 56 | 4.507 | 0.2100 | Yes |
| 11 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [Source:HGNC Symbol;Acc:HGNC:26072] | 59 | 4.474 | 0.2300 | Yes |
| 12 | DHX58 | DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517] | 64 | 4.416 | 0.2496 | Yes |
| 13 | ISG20 | interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] | 65 | 4.413 | 0.2694 | Yes |
| 14 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 67 | 4.389 | 0.2890 | Yes |
| 15 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 82 | 4.215 | 0.3074 | Yes |
| 16 | TRAFD1 | TRAF-type zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24808] | 84 | 4.202 | 0.3262 | Yes |
| 17 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 85 | 4.196 | 0.3450 | Yes |
| 18 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 92 | 4.151 | 0.3634 | Yes |
| 19 | PROCR | protein C receptor [Source:HGNC Symbol;Acc:HGNC:9452] | 94 | 4.136 | 0.3818 | Yes |
| 20 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 132 | 3.896 | 0.3983 | Yes |
| 21 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 134 | 3.887 | 0.4156 | Yes |
| 22 | SAMD9 | sterile alpha motif domain containing 9 [Source:HGNC Symbol;Acc:HGNC:1348] | 139 | 3.871 | 0.4328 | Yes |
| 23 | PARP12 | poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919] | 140 | 3.863 | 0.4501 | Yes |
| 24 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 144 | 3.824 | 0.4671 | Yes |
| 25 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 149 | 3.787 | 0.4839 | Yes |
| 26 | EPSTI1 | epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] | 167 | 3.662 | 0.4999 | Yes |
| 27 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 198 | 3.495 | 0.5147 | Yes |
| 28 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 201 | 3.473 | 0.5302 | Yes |
| 29 | TRIM25 | tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932] | 249 | 3.241 | 0.5434 | Yes |
| 30 | TRIM21 | tripartite motif containing 21 [Source:HGNC Symbol;Acc:HGNC:11312] | 273 | 3.123 | 0.5567 | Yes |
| 31 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 285 | 3.080 | 0.5702 | Yes |
| 32 | UBA7 | ubiquitin like modifier activating enzyme 7 [Source:HGNC Symbol;Acc:HGNC:12471] | 290 | 3.067 | 0.5838 | Yes |
| 33 | PNPT1 | polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166] | 292 | 3.064 | 0.5975 | Yes |
| 34 | MOV10 | Mov10 RISC complex RNA helicase [Source:HGNC Symbol;Acc:HGNC:7200] | 304 | 2.987 | 0.6105 | Yes |
| 35 | PARP9 | poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118] | 309 | 2.964 | 0.6237 | Yes |
| 36 | ADAR | adenosine deaminase RNA specific [Source:HGNC Symbol;Acc:HGNC:225] | 336 | 2.835 | 0.6357 | Yes |
| 37 | OGFR | opioid growth factor receptor [Source:HGNC Symbol;Acc:HGNC:15768] | 344 | 2.803 | 0.6480 | Yes |
| 38 | TENT5A | terminal nucleotidyltransferase 5A [Source:HGNC Symbol;Acc:HGNC:18345] | 361 | 2.735 | 0.6598 | Yes |
| 39 | TDRD7 | tudor domain containing 7 [Source:HGNC Symbol;Acc:HGNC:30831] | 396 | 2.620 | 0.6706 | Yes |
| 40 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 400 | 2.600 | 0.6821 | Yes |
| 41 | TRIM14 | tripartite motif containing 14 [Source:HGNC Symbol;Acc:HGNC:16283] | 403 | 2.596 | 0.6937 | Yes |
| 42 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 433 | 2.515 | 0.7042 | Yes |
| 43 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 442 | 2.499 | 0.7151 | Yes |
| 44 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 457 | 2.456 | 0.7257 | Yes |
| 45 | IFITM2 | interferon induced transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:5413] | 468 | 2.433 | 0.7363 | Yes |
| 46 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 520 | 2.305 | 0.7453 | Yes |
| 47 | IRF9 | interferon regulatory factor 9 [Source:HGNC Symbol;Acc:HGNC:6131] | 524 | 2.304 | 0.7555 | Yes |
| 48 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 525 | 2.303 | 0.7658 | Yes |
| 49 | PSMB9 | proteasome 20S subunit beta 9 [Source:HGNC Symbol;Acc:HGNC:9546] | 527 | 2.297 | 0.7760 | Yes |
| 50 | PSMB8 | proteasome 20S subunit beta 8 [Source:HGNC Symbol;Acc:HGNC:9545] | 582 | 2.169 | 0.7843 | Yes |
| 51 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 585 | 2.161 | 0.7939 | Yes |
| 52 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 606 | 2.135 | 0.8029 | Yes |
| 53 | UBE2L6 | ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490] | 618 | 2.114 | 0.8120 | Yes |
| 54 | CMTR1 | cap methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:21077] | 657 | 2.059 | 0.8202 | Yes |
| 55 | CD47 | CD47 molecule [Source:HGNC Symbol;Acc:HGNC:1682] | 693 | 1.998 | 0.8282 | Yes |
| 56 | IRF1 | interferon regulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:6116] | 704 | 1.969 | 0.8367 | Yes |
| 57 | CASP1 | caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499] | 759 | 1.884 | 0.8437 | Yes |
| 58 | CASP8 | caspase 8 [Source:HGNC Symbol;Acc:HGNC:1509] | 773 | 1.858 | 0.8517 | Yes |
| 59 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 850 | 1.724 | 0.8573 | Yes |
| 60 | TRIM26 | tripartite motif containing 26 [Source:HGNC Symbol;Acc:HGNC:12962] | 881 | 1.686 | 0.8640 | Yes |
| 61 | LAP3 | leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] | 1012 | 1.542 | 0.8674 | Yes |
| 62 | IL7 | interleukin 7 [Source:HGNC Symbol;Acc:HGNC:6023] | 1166 | 1.423 | 0.8696 | Yes |
| 63 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 1267 | 1.338 | 0.8729 | Yes |
| 64 | SP110 | SP110 nuclear body protein [Source:HGNC Symbol;Acc:HGNC:5401] | 1374 | 1.263 | 0.8757 | Yes |
| 65 | PSMA3 | proteasome 20S subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:9532] | 1397 | 1.247 | 0.8807 | Yes |
| 66 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 1842 | 0.989 | 0.8731 | No |
| 67 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 1992 | 0.922 | 0.8732 | No |
| 68 | WARS1 | tryptophanyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12729] | 2535 | 0.724 | 0.8618 | No |
| 69 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 2780 | 0.644 | 0.8581 | No |
| 70 | B2M | beta-2-microglobulin [Source:HGNC Symbol;Acc:HGNC:914] | 3047 | 0.572 | 0.8534 | No |
| 71 | TRIM5 | tripartite motif containing 5 [Source:HGNC Symbol;Acc:HGNC:16276] | 3219 | 0.526 | 0.8512 | No |
| 72 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 3904 | 0.378 | 0.8344 | No |
| 73 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 4523 | 0.265 | 0.8189 | No |
| 74 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 4623 | 0.248 | 0.8173 | No |
| 75 | SELL | selectin L [Source:HGNC Symbol;Acc:HGNC:10720] | 7173 | 0.000 | 0.7484 | No |
| 76 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8710 | 0.000 | 0.7069 | No |
| 77 | BATF2 | basic leucine zipper ATF-like transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:25163] | 8823 | 0.000 | 0.7038 | No |
| 78 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 9164 | 0.000 | 0.6946 | No |
| 79 | RTP4 | receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992] | 10503 | 0.000 | 0.6585 | No |
| 80 | IFI30 | IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398] | 11456 | 0.000 | 0.6327 | No |
| 81 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12458 | 0.000 | 0.6057 | No |
| 82 | IL4R | interleukin 4 receptor [Source:HGNC Symbol;Acc:HGNC:6015] | 13801 | 0.000 | 0.5694 | No |
| 83 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18785 | 0.000 | 0.4347 | No |
| 84 | NMI | N-myc and STAT interactor [Source:HGNC Symbol;Acc:HGNC:7854] | 19186 | 0.000 | 0.4239 | No |
| 85 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 24238 | 0.000 | 0.2874 | No |
| 86 | NUB1 | negative regulator of ubiquitin like proteins 1 [Source:HGNC Symbol;Acc:HGNC:17623] | 27551 | -0.066 | 0.1981 | No |
| 87 | NCOA7 | nuclear receptor coactivator 7 [Source:HGNC Symbol;Acc:HGNC:21081] | 27882 | -0.106 | 0.1897 | No |
| 88 | IRF2 | interferon regulatory factor 2 [Source:HGNC Symbol;Acc:HGNC:6117] | 29040 | -0.259 | 0.1596 | No |
| 89 | C1S | complement C1s [Source:HGNC Symbol;Acc:HGNC:1247] | 29570 | -0.335 | 0.1468 | No |
| 90 | ELF1 | E74 like ETS transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3316] | 30042 | -0.403 | 0.1358 | No |
| 91 | SLC25A28 | solute carrier family 25 member 28 [Source:HGNC Symbol;Acc:HGNC:23472] | 32314 | -0.836 | 0.0782 | No |
| 92 | CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase [Source:HGNC Symbol;Acc:HGNC:2158] | 32976 | -1.008 | 0.0648 | No |
| 93 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 33411 | -1.141 | 0.0582 | No |
| 94 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 33680 | -1.230 | 0.0564 | No |
| 95 | MVB12A | multivesicular body subunit 12A [Source:HGNC Symbol;Acc:HGNC:25153] | 33980 | -1.334 | 0.0543 | No |
| 96 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 36400 | -2.929 | 0.0020 | No |
| 97 | GMPR | guanosine monophosphate reductase [Source:HGNC Symbol;Acc:HGNC:4376] | 36880 | -3.710 | 0.0057 | No |
