Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | HALLMARK_MYC_TARGETS_V2 |
| Enrichment Score (ES) | 0.38663298 |
| Normalized Enrichment Score (NES) | 0.9179508 |
| Nominal p-value | 0.6768293 |
| FDR q-value | 0.7342289 |
| FWER p-Value | 0.961 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 45 | 4.632 | 0.0610 | Yes |
| 2 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 251 | 3.232 | 0.0988 | Yes |
| 3 | IPO4 | importin 4 [Source:HGNC Symbol;Acc:HGNC:19426] | 500 | 2.344 | 0.1236 | Yes |
| 4 | GRWD1 | glutamate rich WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:21270] | 504 | 2.332 | 0.1549 | Yes |
| 5 | RRP9 | ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16829] | 697 | 1.988 | 0.1764 | Yes |
| 6 | UTP20 | UTP20 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:17897] | 1033 | 1.519 | 0.1877 | Yes |
| 7 | RRP12 | ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100] | 1081 | 1.488 | 0.2064 | Yes |
| 8 | NOP2 | NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867] | 1149 | 1.437 | 0.2239 | Yes |
| 9 | NIP7 | nucleolar pre-rRNA processing protein NIP7 [Source:HGNC Symbol;Acc:HGNC:24328] | 1265 | 1.338 | 0.2388 | Yes |
| 10 | NOP16 | NOP16 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:26934] | 1388 | 1.252 | 0.2523 | Yes |
| 11 | WDR43 | WD repeat domain 43 [Source:HGNC Symbol;Acc:HGNC:28945] | 1461 | 1.200 | 0.2665 | Yes |
| 12 | MYBBP1A | MYB binding protein 1a [Source:HGNC Symbol;Acc:HGNC:7546] | 1517 | 1.167 | 0.2807 | Yes |
| 13 | MRTO4 | MRT4 homolog, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:18477] | 1529 | 1.162 | 0.2960 | Yes |
| 14 | HK2 | hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923] | 1655 | 1.084 | 0.3072 | Yes |
| 15 | FARSA | phenylalanyl-tRNA synthetase subunit alpha [Source:HGNC Symbol;Acc:HGNC:3592] | 1668 | 1.075 | 0.3213 | Yes |
| 16 | BYSL | bystin like [Source:HGNC Symbol;Acc:HGNC:1157] | 1872 | 0.978 | 0.3289 | Yes |
| 17 | TCOF1 | treacle ribosome biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:11654] | 2020 | 0.910 | 0.3372 | Yes |
| 18 | PUS1 | pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:15508] | 2094 | 0.880 | 0.3470 | Yes |
| 19 | DDX18 | DEAD-box helicase 18 [Source:HGNC Symbol;Acc:HGNC:2741] | 2114 | 0.871 | 0.3582 | Yes |
| 20 | PPRC1 | PPARG related coactivator 1 [Source:HGNC Symbol;Acc:HGNC:30025] | 2157 | 0.853 | 0.3685 | Yes |
| 21 | HSPE1 | heat shock protein family E (Hsp10) member 1 [Source:HGNC Symbol;Acc:HGNC:5269] | 2206 | 0.836 | 0.3784 | Yes |
| 22 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 2301 | 0.799 | 0.3866 | Yes |
| 23 | MPHOSPH10 | M-phase phosphoprotein 10 [Source:HGNC Symbol;Acc:HGNC:7213] | 2927 | 0.596 | 0.3778 | No |
| 24 | NOC4L | nucleolar complex associated 4 homolog [Source:HGNC Symbol;Acc:HGNC:28461] | 3059 | 0.569 | 0.3819 | No |
| 25 | RCL1 | RNA terminal phosphate cyclase like 1 [Source:HGNC Symbol;Acc:HGNC:17687] | 3444 | 0.472 | 0.3778 | No |
| 26 | HSPD1 | heat shock protein family D (Hsp60) member 1 [Source:HGNC Symbol;Acc:HGNC:5261] | 3495 | 0.462 | 0.3827 | No |
| 27 | PHB | prohibitin [Source:HGNC Symbol;Acc:HGNC:8912] | 3893 | 0.380 | 0.3771 | No |
| 28 | IMP4 | IMP U3 small nucleolar ribonucleoprotein 4 [Source:HGNC Symbol;Acc:HGNC:30856] | 4049 | 0.351 | 0.3776 | No |
| 29 | AIMP2 | aminoacyl tRNA synthetase complex interacting multifunctional protein 2 [Source:HGNC Symbol;Acc:HGNC:20609] | 4788 | 0.222 | 0.3607 | No |
| 30 | WDR74 | WD repeat domain 74 [Source:HGNC Symbol;Acc:HGNC:25529] | 5011 | 0.190 | 0.3572 | No |
| 31 | PES1 | pescadillo ribosomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8848] | 5271 | 0.153 | 0.3523 | No |
| 32 | NOP56 | NOP56 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:15911] | 5322 | 0.145 | 0.3529 | No |
| 33 | SRM | spermidine synthase [Source:HGNC Symbol;Acc:HGNC:11296] | 5347 | 0.140 | 0.3541 | No |
| 34 | LAS1L | LAS1 like ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:25726] | 6323 | 0.006 | 0.3279 | No |
| 35 | GNL3 | G protein nucleolar 3 [Source:HGNC Symbol;Acc:HGNC:29931] | 27438 | -0.053 | -0.2416 | No |
| 36 | TBRG4 | transforming growth factor beta regulator 4 [Source:HGNC Symbol;Acc:HGNC:17443] | 27495 | -0.058 | -0.2423 | No |
| 37 | NPM1 | nucleophosmin 1 [Source:HGNC Symbol;Acc:HGNC:7910] | 27558 | -0.067 | -0.2431 | No |
| 38 | NDUFAF4 | NADH:ubiquinone oxidoreductase complex assembly factor 4 [Source:HGNC Symbol;Acc:HGNC:21034] | 29493 | -0.323 | -0.2910 | No |
| 39 | NOLC1 | nucleolar and coiled-body phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15608] | 29932 | -0.388 | -0.2976 | No |
| 40 | PPAN | peter pan homolog [Source:HGNC Symbol;Acc:HGNC:9227] | 30686 | -0.503 | -0.3112 | No |
| 41 | TFB2M | transcription factor B2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:18559] | 30788 | -0.522 | -0.3069 | No |
| 42 | PRMT3 | protein arginine methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30163] | 31317 | -0.610 | -0.3129 | No |
| 43 | SLC19A1 | solute carrier family 19 member 1 [Source:HGNC Symbol;Acc:HGNC:10937] | 31466 | -0.640 | -0.3084 | No |
| 44 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 32439 | -0.866 | -0.3230 | No |
| 45 | RABEPK | Rab9 effector protein with kelch motifs [Source:HGNC Symbol;Acc:HGNC:16896] | 33002 | -1.017 | -0.3245 | No |
| 46 | TMEM97 | transmembrane protein 97 [Source:HGNC Symbol;Acc:HGNC:28106] | 33383 | -1.132 | -0.3195 | No |
| 47 | SUPV3L1 | Suv3 like RNA helicase [Source:HGNC Symbol;Acc:HGNC:11471] | 33863 | -1.290 | -0.3152 | No |
| 48 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34588 | -1.576 | -0.3135 | No |
| 49 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 35386 | -2.005 | -0.3081 | No |
| 50 | CDK4 | cyclin dependent kinase 4 [Source:HGNC Symbol;Acc:HGNC:1773] | 35505 | -2.086 | -0.2833 | No |
| 51 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35614 | -2.167 | -0.2571 | No |
| 52 | SLC29A2 | solute carrier family 29 member 2 [Source:HGNC Symbol;Acc:HGNC:11004] | 35931 | -2.436 | -0.2330 | No |
| 53 | EXOSC5 | exosome component 5 [Source:HGNC Symbol;Acc:HGNC:24662] | 36005 | -2.504 | -0.2013 | No |
| 54 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36483 | -3.006 | -0.1738 | No |
| 55 | SORD | sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184] | 36574 | -3.127 | -0.1343 | No |
| 56 | CBX3 | chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553] | 36764 | -3.461 | -0.0929 | No |
| 57 | MAP3K6 | mitogen-activated protein kinase kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6858] | 36824 | -3.583 | -0.0464 | No |
| 58 | UNG | uracil DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:12572] | 36965 | -3.986 | 0.0034 | No |
