Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | HALLMARK_PANCREAS_BETA_CELLS |
| Enrichment Score (ES) | -0.6035643 |
| Normalized Enrichment Score (NES) | -1.1254922 |
| Nominal p-value | 0.29746836 |
| FDR q-value | 0.5469694 |
| FWER p-Value | 0.999 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | STXBP1 | syntaxin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11444] | 1046 | 1.508 | 0.0609 | No |
| 2 | SRPRB | SRP receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:24085] | 2378 | 0.773 | 0.0707 | No |
| 3 | SRP14 | signal recognition particle 14 [Source:HGNC Symbol;Acc:HGNC:11299] | 3439 | 0.474 | 0.0701 | No |
| 4 | SEC11A | SEC11 homolog A, signal peptidase complex subunit [Source:HGNC Symbol;Acc:HGNC:17718] | 3577 | 0.445 | 0.0927 | No |
| 5 | AKT3 | AKT serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:393] | 4684 | 0.239 | 0.0770 | No |
| 6 | SPCS1 | signal peptidase complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:23401] | 5821 | 0.080 | 0.0510 | No |
| 7 | SRP9 | signal recognition particle 9 [Source:HGNC Symbol;Acc:HGNC:11304] | 6025 | 0.050 | 0.0485 | No |
| 8 | SCGN | secretagogin, EF-hand calcium binding protein [Source:HGNC Symbol;Acc:HGNC:16941] | 6560 | 0.000 | 0.0341 | No |
| 9 | CHGA | chromogranin A [Source:HGNC Symbol;Acc:HGNC:1929] | 10534 | 0.000 | -0.0731 | No |
| 10 | G6PC2 | glucose-6-phosphatase catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:28906] | 12376 | 0.000 | -0.1228 | No |
| 11 | SST | somatostatin [Source:HGNC Symbol;Acc:HGNC:11329] | 12421 | 0.000 | -0.1240 | No |
| 12 | SYT13 | synaptotagmin 13 [Source:HGNC Symbol;Acc:HGNC:14962] | 13642 | 0.000 | -0.1569 | No |
| 13 | PAX4 | paired box 4 [Source:HGNC Symbol;Acc:HGNC:8618] | 14740 | 0.000 | -0.1865 | No |
| 14 | DCX | doublecortin [Source:HGNC Symbol;Acc:HGNC:2714] | 15996 | 0.000 | -0.2204 | No |
| 15 | PCSK2 | proprotein convertase subtilisin/kexin type 2 [Source:HGNC Symbol;Acc:HGNC:8744] | 16218 | 0.000 | -0.2264 | No |
| 16 | PCSK1 | proprotein convertase subtilisin/kexin type 1 [Source:HGNC Symbol;Acc:HGNC:8743] | 16219 | 0.000 | -0.2264 | No |
| 17 | GCG | glucagon [Source:HGNC Symbol;Acc:HGNC:4191] | 16862 | 0.000 | -0.2437 | No |
| 18 | INS | insulin [Source:HGNC Symbol;Acc:HGNC:6081] | 17652 | 0.000 | -0.2650 | No |
| 19 | DPP4 | dipeptidyl peptidase 4 [Source:HGNC Symbol;Acc:HGNC:3009] | 17829 | 0.000 | -0.2697 | No |
| 20 | NKX2-2 | NK2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:7835] | 19063 | 0.000 | -0.3030 | No |
| 21 | IAPP | islet amyloid polypeptide [Source:HGNC Symbol;Acc:HGNC:5329] | 19113 | 0.000 | -0.3043 | No |
| 22 | NEUROD1 | neuronal differentiation 1 [Source:HGNC Symbol;Acc:HGNC:7762] | 19119 | 0.000 | -0.3045 | No |
| 23 | NEUROG3 | neurogenin 3 [Source:HGNC Symbol;Acc:HGNC:13806] | 19233 | 0.000 | -0.3075 | No |
| 24 | NKX6-1 | NK6 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7839] | 20438 | 0.000 | -0.3400 | No |
| 25 | PDX1 | pancreatic and duodenal homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6107] | 21047 | 0.000 | -0.3564 | No |
| 26 | INSM1 | INSM transcriptional repressor 1 [Source:HGNC Symbol;Acc:HGNC:6090] | 21655 | 0.000 | -0.3728 | No |
| 27 | ISL1 | ISL LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6132] | 21866 | 0.000 | -0.3785 | No |
| 28 | FOXA2 | forkhead box A2 [Source:HGNC Symbol;Acc:HGNC:5022] | 23398 | 0.000 | -0.4198 | No |
| 29 | SLC2A2 | solute carrier family 2 member 2 [Source:HGNC Symbol;Acc:HGNC:11006] | 27080 | 0.000 | -0.5191 | No |
| 30 | ABCC8 | ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59] | 27091 | 0.000 | -0.5194 | No |
| 31 | ELP4 | elongator acetyltransferase complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:1171] | 27642 | -0.074 | -0.5299 | No |
| 32 | GCK | glucokinase [Source:HGNC Symbol;Acc:HGNC:4195] | 28088 | -0.132 | -0.5341 | No |
| 33 | HNF1A | HNF1 homeobox A [Source:HGNC Symbol;Acc:HGNC:11621] | 28187 | -0.143 | -0.5283 | No |
| 34 | VDR | vitamin D receptor [Source:HGNC Symbol;Acc:HGNC:12679] | 29503 | -0.325 | -0.5446 | No |
| 35 | PAK3 | p21 (RAC1) activated kinase 3 [Source:HGNC Symbol;Acc:HGNC:8592] | 30681 | -0.503 | -0.5466 | No |
| 36 | FOXO1 | forkhead box O1 [Source:HGNC Symbol;Acc:HGNC:3819] | 32792 | -0.961 | -0.5468 | Yes |
| 37 | PKLR | pyruvate kinase L/R [Source:HGNC Symbol;Acc:HGNC:9020] | 33619 | -1.208 | -0.4977 | Yes |
| 38 | LMO2 | LIM domain only 2 [Source:HGNC Symbol;Acc:HGNC:6642] | 35242 | -1.913 | -0.4284 | Yes |
| 39 | MAFB | MAF bZIP transcription factor B [Source:HGNC Symbol;Acc:HGNC:6408] | 36840 | -3.618 | -0.2576 | Yes |
| 40 | PAX6 | paired box 6 [Source:HGNC Symbol;Acc:HGNC:8620] | 37056 | -4.471 | 0.0009 | Yes |
