Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | HALLMARK_PEROXISOME |
| Enrichment Score (ES) | -0.6093755 |
| Normalized Enrichment Score (NES) | -1.2606945 |
| Nominal p-value | 0.05381166 |
| FDR q-value | 0.19160004 |
| FWER p-Value | 0.899 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit [Source:HGNC Symbol;Acc:HGNC:3433] | 203 | 3.470 | 0.0215 | No |
| 2 | ATXN1 | ataxin 1 [Source:HGNC Symbol;Acc:HGNC:10548] | 210 | 3.412 | 0.0479 | No |
| 3 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 221 | 3.363 | 0.0737 | No |
| 4 | PRDX5 | peroxiredoxin 5 [Source:HGNC Symbol;Acc:HGNC:9355] | 414 | 2.564 | 0.0885 | No |
| 5 | TSPO | translocator protein [Source:HGNC Symbol;Acc:HGNC:1158] | 637 | 2.096 | 0.0988 | No |
| 6 | ACSL4 | acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571] | 665 | 2.041 | 0.1139 | No |
| 7 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 870 | 1.699 | 0.1216 | No |
| 8 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 998 | 1.554 | 0.1302 | No |
| 9 | BCL10 | BCL10 immune signaling adaptor [Source:HGNC Symbol;Acc:HGNC:989] | 1476 | 1.188 | 0.1266 | No |
| 10 | CNBP | CCHC-type zinc finger nucleic acid binding protein [Source:HGNC Symbol;Acc:HGNC:13164] | 1730 | 1.041 | 0.1278 | No |
| 11 | CDK7 | cyclin dependent kinase 7 [Source:HGNC Symbol;Acc:HGNC:1778] | 1969 | 0.929 | 0.1286 | No |
| 12 | YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta [Source:HGNC Symbol;Acc:HGNC:12853] | 2605 | 0.697 | 0.1169 | No |
| 13 | PEX11A | peroxisomal biogenesis factor 11 alpha [Source:HGNC Symbol;Acc:HGNC:8852] | 2618 | 0.694 | 0.1219 | No |
| 14 | SLC25A19 | solute carrier family 25 member 19 [Source:HGNC Symbol;Acc:HGNC:14409] | 2621 | 0.693 | 0.1273 | No |
| 15 | ERCC3 | ERCC excision repair 3, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3435] | 2766 | 0.646 | 0.1284 | No |
| 16 | VPS4B | vacuolar protein sorting 4 homolog B [Source:HGNC Symbol;Acc:HGNC:10895] | 2964 | 0.587 | 0.1276 | No |
| 17 | SEMA3C | semaphorin 3C [Source:HGNC Symbol;Acc:HGNC:10725] | 4310 | 0.300 | 0.0936 | No |
| 18 | PEX5 | peroxisomal biogenesis factor 5 [Source:HGNC Symbol;Acc:HGNC:9719] | 4433 | 0.282 | 0.0925 | No |
| 19 | DHRS3 | dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693] | 4705 | 0.236 | 0.0870 | No |
| 20 | ITGB1BP1 | integrin subunit beta 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23927] | 4840 | 0.215 | 0.0850 | No |
| 21 | SLC27A2 | solute carrier family 27 member 2 [Source:HGNC Symbol;Acc:HGNC:10996] | 4964 | 0.197 | 0.0832 | No |
| 22 | PABPC1 | poly(A) binding protein cytoplasmic 1 [Source:HGNC Symbol;Acc:HGNC:8554] | 5533 | 0.118 | 0.0688 | No |
| 23 | ACOX1 | acyl-CoA oxidase 1 [Source:HGNC Symbol;Acc:HGNC:119] | 5960 | 0.060 | 0.0577 | No |
| 24 | PEX14 | peroxisomal biogenesis factor 14 [Source:HGNC Symbol;Acc:HGNC:8856] | 6294 | 0.011 | 0.0488 | No |
| 25 | EPHX2 | epoxide hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3402] | 7927 | 0.000 | 0.0047 | No |
| 26 | EHHADH | enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3247] | 7943 | 0.000 | 0.0043 | No |
| 27 | GSTK1 | glutathione S-transferase kappa 1 [Source:HGNC Symbol;Acc:HGNC:16906] | 9658 | 0.000 | -0.0420 | No |
| 28 | ESR2 | estrogen receptor 2 [Source:HGNC Symbol;Acc:HGNC:3468] | 11906 | 0.000 | -0.1028 | No |
| 29 | STS | steroid sulfatase [Source:HGNC Symbol;Acc:HGNC:11425] | 12429 | 0.000 | -0.1169 | No |
| 30 | TTR | transthyretin [Source:HGNC Symbol;Acc:HGNC:12405] | 12680 | 0.000 | -0.1237 | No |
| 31 | HSD11B2 | hydroxysteroid 11-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5209] | 14327 | 0.000 | -0.1682 | No |
| 32 | CEL | carboxyl ester lipase [Source:HGNC Symbol;Acc:HGNC:1848] | 15745 | 0.000 | -0.2065 | No |
| 33 | DIO1 | iodothyronine deiodinase 1 [Source:HGNC Symbol;Acc:HGNC:2883] | 15803 | 0.000 | -0.2080 | No |
| 34 | SERPINA6 | serpin family A member 6 [Source:HGNC Symbol;Acc:HGNC:1540] | 17691 | 0.000 | -0.2590 | No |
| 35 | UGT2B17 | UDP glucuronosyltransferase family 2 member B17 [Source:HGNC Symbol;Acc:HGNC:12547] | 18074 | 0.000 | -0.2694 | No |
| 36 | SULT2B1 | sulfotransferase family 2B member 1 [Source:HGNC Symbol;Acc:HGNC:11459] | 23477 | 0.000 | -0.4154 | No |
| 37 | CRABP2 | cellular retinoic acid binding protein 2 [Source:HGNC Symbol;Acc:HGNC:2339] | 23747 | 0.000 | -0.4227 | No |
| 38 | CRABP1 | cellular retinoic acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2338] | 23748 | 0.000 | -0.4227 | No |
| 39 | SCGB1A1 | secretoglobin family 1A member 1 [Source:HGNC Symbol;Acc:HGNC:12523] | 23933 | 0.000 | -0.4277 | No |
| 40 | HAO2 | hydroxyacid oxidase 2 [Source:HGNC Symbol;Acc:HGNC:4810] | 24586 | 0.000 | -0.4453 | No |
| 41 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 25326 | 0.000 | -0.4653 | No |
| 42 | FABP6 | fatty acid binding protein 6 [Source:HGNC Symbol;Acc:HGNC:3561] | 26494 | 0.000 | -0.4968 | No |
| 43 | ALB | albumin [Source:HGNC Symbol;Acc:HGNC:399] | 26884 | 0.000 | -0.5073 | No |
| 44 | ABCC8 | ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59] | 27091 | 0.000 | -0.5129 | No |
| 45 | CACNA1B | calcium voltage-gated channel subunit alpha1 B [Source:HGNC Symbol;Acc:HGNC:1389] | 27212 | -0.017 | -0.5160 | No |
| 46 | HSD17B11 | hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960] | 27683 | -0.079 | -0.5281 | No |
| 47 | PEX13 | peroxisomal biogenesis factor 13 [Source:HGNC Symbol;Acc:HGNC:8855] | 27712 | -0.084 | -0.5282 | No |
| 48 | ISOC1 | isochorismatase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24254] | 27762 | -0.091 | -0.5288 | No |
| 49 | NR1I2 | nuclear receptor subfamily 1 group I member 2 [Source:HGNC Symbol;Acc:HGNC:7968] | 28453 | -0.179 | -0.5461 | No |
| 50 | FIS1 | fission, mitochondrial 1 [Source:HGNC Symbol;Acc:HGNC:21689] | 28569 | -0.195 | -0.5477 | No |
| 51 | CLN8 | CLN8 transmembrane ER and ERGIC protein [Source:HGNC Symbol;Acc:HGNC:2079] | 28579 | -0.197 | -0.5464 | No |
| 52 | IDI1 | isopentenyl-diphosphate delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:5387] | 28721 | -0.216 | -0.5485 | No |
| 53 | NUDT19 | nudix hydrolase 19 [Source:HGNC Symbol;Acc:HGNC:32036] | 28758 | -0.221 | -0.5478 | No |
| 54 | HRAS | HRas proto-oncogene, GTPase [Source:HGNC Symbol;Acc:HGNC:5173] | 29250 | -0.288 | -0.5588 | No |
| 55 | SLC23A2 | solute carrier family 23 member 2 [Source:HGNC Symbol;Acc:HGNC:10973] | 29497 | -0.324 | -0.5630 | No |
| 56 | SOD1 | superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179] | 29601 | -0.340 | -0.5631 | No |
| 57 | PEX2 | peroxisomal biogenesis factor 2 [Source:HGNC Symbol;Acc:HGNC:9717] | 30321 | -0.444 | -0.5791 | No |
| 58 | CTBP1 | C-terminal binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2494] | 30371 | -0.452 | -0.5769 | No |
| 59 | ACOT8 | acyl-CoA thioesterase 8 [Source:HGNC Symbol;Acc:HGNC:15919] | 30820 | -0.527 | -0.5849 | No |
| 60 | MLYCD | malonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150] | 30903 | -0.540 | -0.5829 | No |
| 61 | ACSL1 | acyl-CoA synthetase long chain family member 1 [Source:HGNC Symbol;Acc:HGNC:3569] | 31206 | -0.590 | -0.5865 | No |
| 62 | ABCB9 | ATP binding cassette subfamily B member 9 [Source:HGNC Symbol;Acc:HGNC:50] | 31527 | -0.652 | -0.5901 | No |
| 63 | ACSL5 | acyl-CoA synthetase long chain family member 5 [Source:HGNC Symbol;Acc:HGNC:16526] | 31905 | -0.739 | -0.5945 | No |
| 64 | PEX6 | peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859] | 32260 | -0.821 | -0.5977 | No |
| 65 | RDH11 | retinol dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:17964] | 32285 | -0.828 | -0.5919 | No |
| 66 | SIAH1 | siah E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:10857] | 32395 | -0.858 | -0.5882 | No |
| 67 | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 [Source:HGNC Symbol;Acc:HGNC:11104] | 32575 | -0.897 | -0.5861 | No |
| 68 | SLC25A17 | solute carrier family 25 member 17 [Source:HGNC Symbol;Acc:HGNC:10987] | 32852 | -0.975 | -0.5860 | No |
| 69 | RXRG | retinoid X receptor gamma [Source:HGNC Symbol;Acc:HGNC:10479] | 33719 | -1.240 | -0.5997 | Yes |
| 70 | LONP2 | lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:HGNC:20598] | 33859 | -1.289 | -0.5935 | Yes |
| 71 | GNPAT | glyceronephosphate O-acyltransferase [Source:HGNC Symbol;Acc:HGNC:4416] | 33892 | -1.302 | -0.5842 | Yes |
| 72 | ABCB1 | ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] | 34365 | -1.485 | -0.5854 | Yes |
| 73 | FDPS | farnesyl diphosphate synthase [Source:HGNC Symbol;Acc:HGNC:3631] | 34489 | -1.536 | -0.5768 | Yes |
| 74 | HMGCL | 3-hydroxy-3-methylglutaryl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:5005] | 34523 | -1.550 | -0.5657 | Yes |
| 75 | SLC25A4 | solute carrier family 25 member 4 [Source:HGNC Symbol;Acc:HGNC:10990] | 34652 | -1.608 | -0.5566 | Yes |
| 76 | ABCD3 | ATP binding cassette subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:67] | 34703 | -1.629 | -0.5453 | Yes |
| 77 | IDE | insulin degrading enzyme [Source:HGNC Symbol;Acc:HGNC:5381] | 34779 | -1.661 | -0.5344 | Yes |
| 78 | PEX11B | peroxisomal biogenesis factor 11 beta [Source:HGNC Symbol;Acc:HGNC:8853] | 35168 | -1.860 | -0.5305 | Yes |
| 79 | CTPS1 | CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519] | 35341 | -1.973 | -0.5198 | Yes |
| 80 | SCP2 | sterol carrier protein 2 [Source:HGNC Symbol;Acc:HGNC:10606] | 35417 | -2.022 | -0.5061 | Yes |
| 81 | ABCD1 | ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61] | 35552 | -2.116 | -0.4933 | Yes |
| 82 | ACAA1 | acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82] | 35654 | -2.203 | -0.4789 | Yes |
| 83 | CAT | catalase [Source:HGNC Symbol;Acc:HGNC:1516] | 35726 | -2.257 | -0.4632 | Yes |
| 84 | DLG4 | discs large MAGUK scaffold protein 4 [Source:HGNC Symbol;Acc:HGNC:2903] | 35770 | -2.295 | -0.4466 | Yes |
| 85 | RETSAT | retinol saturase [Source:HGNC Symbol;Acc:HGNC:25991] | 35792 | -2.309 | -0.4292 | Yes |
| 86 | IDH2 | isocitrate dehydrogenase (NADP(+)) 2 [Source:HGNC Symbol;Acc:HGNC:5383] | 35823 | -2.340 | -0.4118 | Yes |
| 87 | CADM1 | cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5951] | 35916 | -2.422 | -0.3955 | Yes |
| 88 | ECI2 | enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601] | 35927 | -2.434 | -0.3768 | Yes |
| 89 | CRAT | carnitine O-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2342] | 36149 | -2.664 | -0.3621 | Yes |
| 90 | HSD17B4 | hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213] | 36219 | -2.736 | -0.3427 | Yes |
| 91 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36339 | -2.870 | -0.3236 | Yes |
| 92 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 36365 | -2.887 | -0.3018 | Yes |
| 93 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 36426 | -2.958 | -0.2804 | Yes |
| 94 | ABCC5 | ATP binding cassette subfamily C member 5 [Source:HGNC Symbol;Acc:HGNC:56] | 36427 | -2.958 | -0.2574 | Yes |
| 95 | ALDH9A1 | aldehyde dehydrogenase 9 family member A1 [Source:HGNC Symbol;Acc:HGNC:412] | 36441 | -2.969 | -0.2347 | Yes |
| 96 | HSD3B7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 [Source:HGNC Symbol;Acc:HGNC:18324] | 36463 | -2.987 | -0.2121 | Yes |
| 97 | ECH1 | enoyl-CoA hydratase 1 [Source:HGNC Symbol;Acc:HGNC:3149] | 36482 | -3.006 | -0.1892 | Yes |
| 98 | ABCB4 | ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45] | 36583 | -3.137 | -0.1675 | Yes |
| 99 | ELOVL5 | ELOVL fatty acid elongase 5 [Source:HGNC Symbol;Acc:HGNC:21308] | 36598 | -3.154 | -0.1434 | Yes |
| 100 | DHCR24 | 24-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2859] | 36670 | -3.276 | -0.1198 | Yes |
| 101 | IDH1 | isocitrate dehydrogenase (NADP(+)) 1 [Source:HGNC Symbol;Acc:HGNC:5382] | 36928 | -3.878 | -0.0966 | Yes |
| 102 | CLN6 | CLN6 transmembrane ER protein [Source:HGNC Symbol;Acc:HGNC:2077] | 36957 | -3.970 | -0.0665 | Yes |
| 103 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 37018 | -4.241 | -0.0352 | Yes |
| 104 | ABCD2 | ATP binding cassette subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:66] | 37080 | -4.769 | 0.0003 | Yes |
